Job Title: Director, Immunology Cell Therapy Discovery Location: Waltham, MA Hybrid Working: 3 days per week in the office About the Position AstraZeneca, a global leader in biopharmaceuticals, is committed to discoverin…
Skills: Cell Therapy Discovery, Immunological Disease Biology, Strategic Leadership, Ex Vivo Technologies, In Vivo Technologies
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$225k–$338k/yr
Full-time
postgraduate degree
401(k) plan, Paid vacation, Paid holidays, Paid leaves, Medical insurance, Prescription drug coverage
Posted 15d ago
Apply by Aug 13
~40 hrs/week
Responsibilities
Lead ex vivo and in vivo cell therapy discovery efforts to build a robust pipeline for immunological diseases. Manage a high-performing team and collaborate across functions to advance programs from discovery through regulatory stages.
Requirements
Requires a PhD in Immunology or a related field with 5-10 years of industry experience in immunological disease biology. Must have a proven track record of leading scientific teams and a deep understanding of the cell therapy regulatory landscape.
Full job description
Job Title: Director, Immunology Cell Therapy Discovery Location: Waltham, MA
Hybrid Working: 3 days per week in the office
About the Position
AstraZeneca, a global leader in biopharmaceuticals, is committed to discovering and delivering innovative therapies that transform patient outcomes. We areseekingan experienced and visionary Director to join our Immunology Cell Therapy Discovery team. The role focuses on leading bothex vivoandin vivocell therapy discovery efforts, underpinned by an in-depth understanding of immunological disease biology discovery.
Key responsibilities
Strategic leadership: Develop and execute strategy to advance cell therapy discovery,leveragingstate‑of‑the‑artex vivoandin vivocell therapytechnologies tohelpbuild a robust pipeline.
Scientific domainexpertise:Maintaina comprehensive,up‑to‑dateunderstanding of the immunologicaldisease landscape and emerging trends to inform program direction and targetselection.
Cross‑functionalcollaboration: Partner with discovery, translational, preclinical, CMC, and regulatory colleagues to progress programs and expand AstraZeneca’s immunologycell therapyportfolio.
Team leadership: Build, mentor, and lead ahigh‑performingteam; foster a culture of innovation, scientific rigor, accountability, and agility.
Stakeholder engagement: Align strategies and milestones with internal and external stakeholders and consortia to accelerate delivery against R&Dobjectives.
Compliance and governance: Ensure adherence to all applicable laws, regulations, and company policies related to the research and development of medicines.
Assay and process development: Direct the development ofin vitroassays and research processes to evaluate,optimize, andvalidatenovel cell therapy modalities and mechanisms.
Required qualifications
Education: PhD (or equivalent) in Immunology, Molecular or Cell Biology, Bioengineering, ora relatedfield.
5-10 years of relevant industry experience.
Scientificexpertise:Demonstratedin‑depthunderstanding of immunological disease biology, including B and Tcellmediatedimmunologicaldiseases such as multiple sclerosis, inflammatory bowel disease, rheumatoid arthritis, allergy & asthma, fibrosis etc.
Leadership: Proventrack recordof leading scientific teams anddelivering onstrategic initiatives in a dynamic, matrixed environment.
Collaboration and communication: Excellent interpersonal, communication, andstakeholder‑managementskills across functions and organizational levels.
Regulatory understanding: Comprehensive knowledge of the regulatory landscape for cell therapy and genetic engineering.
Preferred qualifications
Vector and construct design: Experience designing andengineeringlentiviral, retroviral, or AAV vectors.
Genetic engineering:Hands‑onexperience applying CRISPR or related tools to innovate and refine cell therapies.
External network: Established relationships withinthe celltherapy, genetic engineering, and immunology communities.
Publications: Strong record ofpeer‑reviewedpublications in vector engineering, cell therapy engineering, or related fields.
If you are passionate about leading and innovating in the field of immunology cell therapy, we invite you to consider this pivotal opportunity at AstraZeneca. Join us in our mission to transform patient outcomes through groundbreaking scientific discovery.
The annual base pay ranges from $225,208 - 337,812. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Date Posted
24-Jul-2026
Closing Date
12-Aug-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
We're transforming the future of healthcare by unlocking the power of what science can do for people, society and the planet. For more information, visit www.astrazeneca.com.
Community Guidelines: bit.ly/2MgAcio
Offices: 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, Cambridgeshire CB2 0AA, GB · Astraallen, Sodertalje, Stockholm County 152 57, SE
PharmaceuticalBiopharmaceuticalInnovationResearch and developmentand Global businessHealth CareBiopharmaBiotechnologyMedicalPrecision Medicine
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