About Us Hawthorne Health is a leading community site network and home research visit solution provider, with 20+ sites and more than 2,000 research experienced healthcare professionals across the U.S. Hawthorne leverage…
Skills: Clinical Research, Principal Investigator, ICH-GCP Guidelines, FDA Regulations, Team Leadership
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Contract
postgraduate degree
Posted 8d ago
~5 hrs/week
Responsibilities
The Principal Investigator will oversee and manage all aspects of clinical trials at the research site, ensuring adherence to study protocols and regulatory requirements. They will lead the clinical research team, conduct remote patient assessments, and make critical medical decisions regarding participant care.
Requirements
Candidates must hold an MD or DO degree with a current, unrestricted medical license and have experience as a Principal Investigator on at least three sponsor-initiated clinical trials. Strong leadership skills and in-depth knowledge of ICH-GCP guidelines and FDA regulations are required.
Full job description
About Us
Hawthorne Health is a leading community site network and home research visit solution provider, with 20+ sites and more than 2,000 research experienced healthcare professionals across the U.S. Hawthorne leverages convenient, trusted, healthcare locations, identified patient data, and intelligent technology to accelerate patient access, improve retention, and reduce study costs. By embedding high-quality research within local communities, Hawthorne makes clinical trials more accessible and convenient for patients. Our community-based model shortens timelines and helps bring better treatments to market, faster.
About the Role
Hawthorne Health is seeking an experienced, Principal Investigator MD on a 1099 contract opportunity to join our growing team and lead the investigation for our site in Concord, NC.
\nResponsibilities
Accurately document findings and contribute to ongoing clinical trials, registries, or research protocols as applicable.
Oversee and manage all aspects of clinical trials conducted at the research site, ensuring adherence to the study protocol, Good Clinical Practice (GCP), ICH guidelines, and all applicable regulatory requirements.
Lead and supervise the clinical research team, including sub-investigators, study coordinators, and other site staff.
Delegate study-related duties appropriately to qualified personnel and ensure proper training and oversight.
Conduct remote review of patient assessments, including physical exams, medical histories, and eligibility screenings, to ensure appropriate participant enrollment.
Review and interpret laboratory results, ECGs, and other diagnostic tests.
Make critical medical decisions regarding participant care, adverse events, and protocol deviations.
Ensure accurate, complete, and timely collection and documentation of all study data.
Communicate effectively with sponsors, Contract Research Organizations (CROs), Institutional Review Boards (IRBs), and regulatory authorities.
Manage investigational product accountability, storage, and administration according to protocol and with the help of the on-site IP team.
Participate in site initiation visits, monitoring visits, audits, and inspections.
Maintain continuous medical education and stay current with advancements in clinical research and relevant therapeutic areas.
Requirements
Experience as a Principal Investigator on at least 3 sponsor initiated clinical trials.
Medical Doctor (M.D. or equivalent) degree from an accredited institution.
Current, unrestricted medical license.
Board certification in a relevant specialty preferred.
Demonstrated in-depth knowledge of ICH-GCP guidelines, FDA regulations, and other relevant ethical and regulatory requirements for clinical research.
Proven leadership and team management skills.
Excellent clinical judgment and decision-making abilities.
Strong verbal and written communication skills in English, with the ability to present complex information clearly and concisely.
Exceptional organizational skills and meticulous attention to detail.
Ability to manage multiple complex studies simultaneously and prioritize tasks effectively.
Commitment to ethical conduct and patient safety.
Location & Time Commitment
3-5 hours per week of remote clinical oversight.
This position requires being on site in Concord, NC ~2 times per month for key visits.
\n
$250 - $250 an hour
Position Type: Part-time, 1099 contract
Compensation: Hourly; rate negotiable based on experience
\n
Hawthorne Health is transforming the clinical trial landscape through an innovative site model that integrates research into community-based settings like local pharmacies. By meeting patients where they already receive care, we are improving access, strengthening trust, and driving more inclusive and efficient trials.
We welcome the opportunity to connect with individuals interested in being part of this evolving mode
Hawthorne Health is the leading community site network, with 75+ locations across the U.S. and a mission to make clinical trials more accessible. Supporting 11+ therapeutic areas and partnering with more than 40 study sponsors, Hawthorne leverages intelligent technology to expand patient access, improve retention, and reduce study costs. By embedding high-quality, compliant research within local communities, Hawthorne streamlines the trial process, making it scalable, cost-effective, and patient-centric. This approach helps shorten timelines and bring better treatments to the market faster. To learn more, visit: www.hawthornehealth.com.
For careers, all official communication from our recruitment team will come from email addresses ending in @hawthornehealth.com. If you receive outreach from any other domain, we advise you to disregard the message and report it as phishing.
Offices: 2121 N California Blvd, #230, Walnut Creek, California 94596, US
How much do Healthcare jobs in North Carolina pay?
Based on 2252 listings with disclosed salaries, most healthcare jobs in North Carolina pay between $59k–$162k per year. Individual offers vary with seniority, company size, and specialization.
How many Healthcare jobs are open in North Carolina right now?
There are currently 17,557 open healthcare positions in North Carolina listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Healthcare roles in North Carolina?
Companies currently hiring include American Addiction Centers, Duke Health Technology Solutions, CVS Health, Duke University Hospital, PruittHealth, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Healthcare jobs in North Carolina?
Yes — 1796 of the 17557 open healthcare positions offer remote or hybrid work (660 remote, 1136 hybrid).
How do I apply for Healthcare jobs in North Carolina?
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