Title: Associate Director, Clinical Pharmacology Location: Thousand Oaks, CA or San Francisco, CA Company Description: Latigo Biotherapeutics, Inc. is a private, early-stage biotechnology company focused on discovering a…
Skills: Clinical Pharmacology, Small Molecule Development, Phase 1 Study Design, PK Analysis, Phoenix WinNonLin
Job Summary: VFC Field Representative is responsible for assessing immunization coverage rates, and compliance with federal and state requirements of the VFC program and promoting best practices for immunization services…
Skills: Immunization Coverage Assessment, Federal and State Compliance, Health Education, Program Implementation, Liaison Coordination
San Francisco, California, United States · On-site
Mid level$9.0B raised
Overview Company Overview: Elevate your security career with Allied Universal® Enhanced Protection Services, a global leader in security and threat mitigation. We specialize in risk consulting, executive protection, inte…
Skills: Close Protection, Firearms Proficiency, Access Control, Surveillance Systems, Emergency Medical Aid
Member of Technical Staff, PM-T, Frontier AI & Robotics (FAR)
San Francisco, California, United States · On-site
Senior+$35B raised
We are seeking a Product Manager, Data Strategy & Physical AI to define and execute the long-term product vision for FAR's AI-powered robotics platform. The intersection of foundation models and physical intelligence is …
Skills: Technical Product Management, AI/ML Strategy, Robotics, Data Strategy, Foundation Models
San Francisco, California, United States · Remote OK
$120k–$150k/yr
Mid level$125M raised
About Us Fieldguide is establishing a new state of trust for global commerce and capital markets through automating and streamlining the work of assurance and audit practitioners specifically within cybersecurity, privac…
San Francisco, California, United States · On-site
$19/hr–$22/hr
Entry level
Compensation TypeHourly Highgate Hotels Highgate is a leading real estate investment and hospitality management company with over $15 billion of assets under management and a global portfolio of more than 400 hotels span…
San Francisco, California, United States · On-site
$200k–$250k/yr
Senior+$6.8B raised
Tishman Speyer creates vibrant destinations and dynamic environments that inspire innovation and connected communities. As a diversified developer, operator, and investment manager of top-tier real estate in 33 markets a…
Skills: Real Estate Development, Project Management, Financial Modeling, Zoning Laws, Public Finance
San Francisco, California, United States · Remote OK
$160k–$250k/yr
Senior$42M raised
The Opportunity Focal is the world's first autonomous personal comfort platform: an AI-enabled robotic heating system that delivers individualized warmth to each guest in real time. Rather than conditioning entire spaces…
San Francisco, California, United States · On-site
$23/hr
Entry level
Life changing work * Welcoming staff * Generous benefits * Advancement opportunities Join the St. Vincent de Paul Society of San Francisco and be part of the solution to break the cycles of homelessness and domestic viol…
Skills: Cleaning, Sanitizing, OSHA Compliance, English Communication, Spanish Communication
San Francisco, California, United States · On-site
Mid level
About the role We're hiring for our first growth hire - someone who can define how our company gets discovered, understood, and loved. This isn't a traditional growth role. You won't be managing acquisition channels or o…
San Francisco, California, United States · On-site
$60k–$75k/yr
Entry level
Job Purpose: BTIG seeks a motivated and detail-oriented Compliance Analyst to join our Compliance team. This entry-level role is critical in supporting the firm’s Compliance program, ensuring that BTIG is adherence with …
San Francisco, California, United States · On-site
$24/hr
Entry level
Life changing work * Welcoming staff * Generous benefits * Advancement opportunities Join the St. Vincent de Paul Society of San Francisco and be part of the solution to break the cycles of homelessness and domestic viol…
Skills: Client Advocacy, Crisis Management, Data Entry, Microsoft Word, Communication
Senior Director of Investor Relations and Capital Markets
San Francisco, California, United States · On-site
$220k–$260k/yr
Senior+$353M raised
Netradyne harnesses the power of Computer Vision and Edge Computing to revolutionize the modern-day transportation ecosystem. We are a leader in fleet safety solutions. With growth exceeding 4x year over year, our soluti…
Skills: Investor Relations, Capital Markets, Financial Modeling, Strategic Thinking, Executive Communication
Administrative Assistant - Early Start Starting Salary Range: $47,618 - $57,141 GGRC is looking hire an Administrative Assistant to provide administrative support of the Early Start Program to maximize efficient operatio…
Skills: Administrative Support, Case Management, Data Collection, Report Preparation, Customer Service
ABOUT THE ROLE Descript is at an inflection point. We have 50M+ users, genuine product-market fit, and a real opportunity to move upmarket—converting high-fit self-serve users into consolidated enterprise contracts and g…
About the Role Our vision is to build the next generation platform to enable easy and fast creation of audio and video content powered by cutting-edge AI. Building a revolutionary way to record, transcribe, edit, and mix…
Medicaid Waiver Nurse Starting Salary Range: $63,011 - $75,613 This position determines eligibility for the Medicaid Waiver program in compliance with Federal and State regulations. This position also provides trainings …
Skills: Medicaid Waiver Eligibility, Case Management, Nursing Care, Regulatory Compliance, Clinical Documentation
San Francisco, California, United States · On-site
$24/hr–$27/hr
Mid level
Pay: Ranging from $24.75 - 27.75/hr + Overtime + Full Benefits (Field-Based, Vehicle Required, Mileage & Toll reimbursements - 72.5 cents per mile). Who we are CloudKitchens helps restaurateurs around the world succeed i…
San Francisco, California, United States · On-site
$24/hr–$27/hr
Mid level$1.3B raised
Pay: Ranging from $24.75 - 27.75/hr + Overtime + Full Benefits (Field-Based, Vehicle Required, Mileage & Toll reimbursements) Who we are CloudKitchens helps restaurateurs around the world succeed in online food delivery …
San Francisco, California, United States · On-site
$65k–$75k/yr
Mid level$2.6B raised
At Compass, our mission is to help everyone find their place in the world. Founded in 2012, we’re revolutionizing the real estate industry with our end-to-end platform that empowers residential real estate agents to deli…
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
$205k–$235k/yr
Full-time
postgraduate degree
Posted 31d ago
~40 hrs/week
Responsibilities
The Associate Director will lead the clinical pharmacology strategy and oversight for multiple clinical and Pre-IND programs from first-in-human to registration. This includes designing studies, authoring regulatory documents, and managing external consultants and vendors.
Requirements
Candidates should possess a PharmD or PhD with over 8 years of experience in clinical pharmacology supporting early development of small molecules. Proficiency in Phoenix WinNonLin and experience with Phase 1 studies and regulatory submissions are highly preferred.
Full job description
Title: Associate Director, Clinical Pharmacology
Location: Thousand Oaks, CA or San Francisco, CA
Company Description:
Latigo Biotherapeutics, Inc. is a private, early-stage biotechnology company focused on discovering and developing the next generation of non-opioid medicines for pain and pain-related syndromes. Our mission is the development of novel therapies that transform the lives of patients. We have a robust pipeline with programs ranging from preclinical to late phase. The company, whose headquarters is in Thousand Oaks, CA, with a satellite office in San Francisco, CA, has a highly successful management team as well as an experienced Board of Directors. At Latigo, we value honest science, patient-focus, and innovation.
Position Description:
Reporting to the Head of Clinical Pharmacology, the Associate Director, Clinical Pharmacology will work in our clinical development teams, with significant responsibility for the Clinical Pharmacology package of multiple clinical and Pre-IND programs. In this role, you will help formulate clinical pharmacology strategies from the FIH through registration.
Primary Responsibilities:
As part of the development team, you will provide expertise in the clinical development of small molecule programs, in particular the design and oversight for clinical pharmacology studies.
Lead and manage design and conduct of clinical pharmacology studies of increasing complexity.
Analyze, interpret and author documents for clinical submissions, including but not limited to clinical study protocols and reports, Investigator’s Brochures, and the clinical pharmacology sections of regulatory submissions.
Interact with regulatory agencies (US and ex-US) as needed.
You will be accountable for study-to-program level clinical pharmacology aspects of compounds in the discovery to development stage.
You will be responsible for oversight and interaction with consultants and vendors assigned to support clinical pharmacology tasks including PK, PKPD, and clinical assay development.
Qualifications and Requirements:
PharmD or PhD in a relevant discipline preferred.
8+ years of experience in Clinical Pharmacology supporting early development in a biotech or pharmaceutical organization.
Prior, robust clinical pharmacology experience with small molecules is required. Experience in the design and conduct of multiple types of Phase 1 studies (e.g. FIH, DDI, FE, rBA, etc.) preferred.
Proficiency with modern PK analysis software (e.g. Phoenix WinNonLin) required.
Knowledge of regulatory requirements for clinical pharmacology preferred.
Strong interpersonal skills, and ability to influence development program teams.
Excellent verbal and written communication skills, and ability to clearly convey complex concepts to technical and non-technical audiences preferred.
Ability to work independently in a dynamic and fast-paced environment.
Experience in therapeutic areas related to pain management preferred.
Experience with regulatory submissions in early and late development is preferred.
Related keywords
Clinical PharmacologySmall MoleculesFIHDDIFErBAPhoenix WinNonLinPKPKPDInvestigator's BrochuresPre-INDBiotechnologyPain ManagementRegulatory AffairsClinical DevelopmentClinical Assay Development
Latigo Biotherapeutics is a private clinical-stage biopharmaceutical company committed to developing innovative non-opioid pain medicines designed to stop the transmission of pain without the risk of addiction, with the goal to provide effective, rapid-acting pain relief. Latigo is supported by leading investors, including Westlake Village BioPartners, Foresite Capital, 5AM Ventures, and Blue Owl Capital. Latigo’s lead program is LTG-001, an oral, selective Nav1.8 inhibitor in development to treat acute pain.