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Science & Research Jobs in San Francisco, CA (Now Hiring) — 1,407 open

Compresr

Founding Engineer

San Francisco, California, United States · Hybrid

Mid levelVisa sponsorship

Type: Full-time permanent contract or an Internship with a potential follow-up offer Location: San Francisco or remote with future relocation to San Francisco (sponsored) Start: ASAP About us We're building state-of-the-…

Skills: Python, FastAPI, PostgreSQL, Redis, AWS

Embedding VC logoEmbedding VC

Member of Technical Staff - Product Engineer

San Francisco, California, United States · On-site

Mid level

Introducing Moonlake, AI for creating world simulations. About Moonlake Moonlake is building the frontier of interactive world models: systems that generate, simulate, and reason over 3D environments for embodied AI, rob…

Skills: React, Next.js, TypeScript, Python, Full-stack Engineering

Embedding VC logoEmbedding VC

Member of Technical Staff - Simulation Engineer

San Francisco, California, United States · On-site

Mid level

Introducing Moonlake, AI for creating world simulations. About Moonlake Moonlake is building the frontier of interactive world models: systems that generate, simulate, and reason over 3D environments for robotics, embodi…

Skills: Robotics Simulation, Physics Simulation, Sim-to-Real Transfer, Python, C++

Embedding VC logoEmbedding VC

Member of Technical Staff - Robotics & Simulation

San Francisco, California, United States · On-site

Mid level

Introducing Moonlake, AI for creating world simulations. About Moonlake Moonlake is building the frontier of AI-powered world simulation. We create systems that generate, simulate, and reason over rich 3D environments fo…

Skills: Robotics Engineering, Machine Learning, Robot Simulation, Python, Sim-to-Real Transfer

Medra logoMedra

Systems Test Engineer - Contract

San Francisco, California, United States · On-site

Entry level$63M raised

What We’re Building: At Medra, our mission is to use AI, robotics, and biology to accelerate life science research, with the ultimate goal of eradicating disease. We have been quietly building the foundational layers of …

Skills: Robotics, Automation, Mechatronics, Troubleshooting, Incident Reporting

Lyft logoLyft

Staff Applied Scientist

San Francisco, California, United States · Hybrid

$194k–$242k/yr

Mid level$5.8B raised

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. As an Applied Scientist specializing in Machine Lea…

Skills: Machine Learning, Operations Research, Python, Mathematical Modeling, Optimization Models

Sentient Foundation logoSentient Foundation

Head of Product

San Francisco, California, United States · Remote OK

Senior

About Sentient The Sentient Foundation is building the open-source future of intelligence: AI aligned with humanity and never controlled by a single entity. We’re a neutral, transparent steward of the open AGI ecosystem,…

Skills: Product Management, AI/ML, Developer Platforms, LLMs, AI Agents

Stripe logoStripe

Investment Lead

San Francisco, California, United States · Remote OK

Senior$9.4B raised

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their …

Skills: Biotech Investing, Portfolio Management, Scientific Diligence, Grantmaking, Immunology

Olema Oncology logoOlema Oncology

Senior Director of Trade and Channel Management

San Francisco, California, United States · On-site

$270k–$300k/yr

Senior+$765M raised

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Te…

Skills: Trade and Distribution Strategy, Specialty Pharmacy Management, 3PL Management, Gross-to-Net Strategy, Contract Negotiation

Anthropic logoAnthropic

Staff Software Engineer, Environments Infrastructure

San Francisco, California, United States · Hybrid

$405k–$605k/yr

Senior+Visa sponsorship$64B raised

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of co…

Skills: Python, API Design, Framework Design, Distributed Systems, Asyncio

TypeSafe AI logoTypeSafe AI

Member of Staff

San Francisco, California, United States · On-site

SeniorVisa sponsorship

TypeSafe is a frontier model lab. We build reliable and general AI systems to power economically valuable automation. Our mission is to usher in a new era of Transformative Artificial Intelligence (TAI): technology with …

Skills: Entrepreneurship, Strategic Thinking, First-principles Reasoning, Problem Solving, Ownership

Anthropic logoAnthropic

Research Scientist, Takeoff Intel

San Francisco, California, United States · Hybrid

$350k–$850k/yr

SeniorVisa sponsorship$64B raised

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of co…

Skills: Large Language Models, Pretraining, Fine-tuning, Reinforcement Learning, Evaluation Design

Thea Pharma US logoThea Pharma US

Territory Manager - San Francisco, CA

San Francisco, California, United States · On-site

$80k–$145k/yr

Mid level

COMPANY Thea Pharma Inc. is the newly established US commercial organization of French-based pharmaceutical company, Laboratoires Théa (Clermont-Ferrand). Thea Pharma markets a suite of leading eye-care drugs that have b…

Skills: Territory Management, Pharmaceutical Sales, Customer Relationship Management, Clinical Education, Product Detailing

Thinking Machines Lab logoThinking Machines Lab

Operations Analyst, Safety

San Francisco, California, United States · On-site

$190k–$300k/yr

Mid levelVisa sponsorship$2.0B raised

Thinking Machines Lab's mission is to empower humanity through advancing collaborative general intelligence. We're building a future where everyone has access to the knowledge and tools to make AI work for their unique n…

Skills: Content Moderation, Trust & Safety, Policy Definition, Abuse Detection, Cybersecurity Abuse

Samsara logoSamsara

Sr. Software Engineer II, AI Platform

San Francisco, California, United States · Remote OK

$131k–$198k/yr

Senior$930M raised

Who we are Samsara (NYSE: IOT) is the pioneer of the Connected Operations™ Cloud, which is a platform that enables organizations that depend on physical operations to harness Internet of Things (IoT) data to develop acti…

Skills: Python, GenAI Frameworks, Distributed Systems, LLM Integration, Prompt Orchestration

Anthropic logoAnthropic

Technical Documentation and Content Engineer, Claude Docs

San Francisco, California, United States · Hybrid

$270k–$320k/yr

SeniorVisa sponsorship$64B raised

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of co…

Skills: Technical Writing, Information Architecture, Software Engineering, Python, TypeScript

Allergan logoAllergan

Scientist 1, Oncology | Drug Discovery

San Francisco, California, United States · On-site

Entry level

Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable imp…

Skills: Bioassay Development, Target-binding Potency Assays, ELISA, TR-FRET, Octet

Faire logoFaire

Senior Applied AI/ML Scientist - Retailer

San Francisco, California, United States · Hybrid

$211k–$291k/yr

Mid level$1.7B raised

About Faire Faire is a technology wholesale platform built on the belief that the future is local. Independent retailers around the globe collectively represent a multi-hundred-billion-dollar wholesale market that has hi…

Skills: Machine Learning, Python, Java, Kotlin, C++

Samara Aerospace

Senior Assembly, Integration and Test Engineer

San Francisco, California, United States · On-site

$150k–$175k/yr

Senior

About Us: Samara Aerospace is revolutionizing satellite design by addressing the challenges of deploying and managing large satellite constellations. Our innovative Hummingbird spacecraft bus offers a modular and scalabl…

Skills: Spacecraft AIT, Systems Engineering, Environmental Testing, Requirements Traceability, Verification and Validation

GoFundMe logoGoFundMe

Senior Staff, Market Research & Consumer Insights

San Francisco, California, United States · Hybrid

$223k–$335k/yr

Senior+

Want to help us help others? We’re hiring! GoFundMe is the world’s most powerful community for good, dedicated to helping people help each other. By uniting individuals and nonprofits in one place, GoFundMe makes it easy…

Skills: Market Research, Consumer Insights, Audience Segmentation, Persona Development, Brand Tracking

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Showing 1–20 of 1,407

Founding Engineer

Compresr

San Francisco, California, United States • Hybrid

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Mid levelVisa sponsorship

Tired of cold applications?

Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.

  • Full-time
  • Visa sponsorship available
  • Posted 10h ago
  • ~40 hrs/week

Responsibilities

Build and own the end-to-end development of a state-of-the-art context compression layer for LLM pipelines. Scale AI infrastructure products within a high-paced startup environment operating like a research lab.

Requirements

Requires strong backend fundamentals with experience in Python, concurrency, and distributed systems. Ability to work across the full stack and proficiency with tools like Claude Code is expected.

Full job description

Type: Full-time permanent contract or an Internship with a potential follow-up offer

Location: San Francisco or remote with future relocation to San Francisco (sponsored)

Start: ASAP

About us

  • We're building state-of-the-art context compression. Our mission is to become the "Cloudflare for LLMs" — a compression layer embedded into most LLM pipelines by default.

  • We're a team of ex-EPFL MSc/PhDs from dlab. We started by publishing papers, then got into YC and started making money helping companies cut their LLM costs.

  • We run the business like a research lab: form hypotheses, kill the ones that don't work, double down on the ones that do.

About you:

  • A cracked full-stack engineer who enjoys a high-paced startup environment, takes pride in what they build and owns it end to end.

  • Python/basic ML Ops skills. Experience in scaling AI infra products is a plus.

  • Proactive, strong communicator with fast response time, team player

Tech Requirements

  • Strong backend engineering fundamentals

  • Experience with concurrency and distributed systems

  • Ability to work across systems (Python + light frontend)

  • Excellent Claude Code (or similar) user

Nice to have

  • Open-source contributions

  • Startup experience

  • OAuth / API auth flows

Stack

  • Backend: Python, FastAPI, PostgreSQL (Supabase), Redis, AWS

  • Frontend: Next.js, React, TypeScript

  • Tools: GitHub, Docker, Sentry, GitHub Actions

Interview process

1. Intro call (20 min)

2. Practical technical interview (60 min)

3. Culture interview (30 min)

Related keywords

LLMContext CompressionPythonFastAPIPostgreSQLSupabaseRedisAWSNext.jsReactTypeScriptGitHubDockerSentryGitHub ActionsML Ops

Frequently asked questions

How much do Science & Research jobs in San Francisco, CA pay?

Based on 1008 listings with disclosed salaries, most science & research jobs in San Francisco, CA pay between $90k–$295k per year. Individual offers vary with seniority, company size, and specialization.

How many Science & Research jobs are open in San Francisco, CA right now?

There are currently 1,407 open science & research positions in San Francisco, CA listed on Clera. New openings are added daily as companies post roles.

Which companies are hiring for Science & Research roles in San Francisco, CA?

Companies currently hiring include UCSF Department of Anesthesia and Perioperative Care, OpenAI, Anthropic, Sutter Health, Astranis Space Technologies, among others. Browse the listings above to see every active employer.

Are there remote or hybrid Science & Research jobs in San Francisco, CA?

Yes — 571 of the 1407 open science & research positions offer remote or hybrid work (126 remote, 445 hybrid).

How do I apply for Science & Research jobs in San Francisco, CA?

Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.

Science & Research jobs in other cities

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Other jobs in San Francisco, CA

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