Cambridge, Massachusetts, United States · Hybrid
$153k–$283k/yr
Job Description Summary #LI-Onsite Location: Cambridge, MA, USA About the Role We are seeking an accomplished Associate Director to join our discovery organization and lead scientific strategy across ADC payloads, linker…
Skills: ADC Payloads, Linker Technologies, Conjugation Approaches, Oncology Drug Discovery, Cancer Biology
Cambridge, Massachusetts, United States · Hybrid
$90k–$136k/yr
At Toyota Research Institute (TRI), we’re on a mission to improve the quality of human life. We’re developing new tools and capabilities to amplify the human experience. To lead this transformative shift in mobility, we’…
Skills: Endpoint Management, Identity And Access Management, MacOS, Windows, Linux
Cambridge, Massachusetts, United States · On-site
$95k–$245k/yr
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Electromechanical Integration, System Testing, Technical Leadership, People Management, Verification And Validation
Pittsfield, Massachusetts, United States · Hybrid
$124k–$138k/yr
Basic Qualifications Requires a Bachelor’s degree in Electrical Engineering, or a related Science, Engineering, Technology or Mathematics field. Also requires 5+ years of job-related experience, or a Master's degree plus…
Skills: Analog Design, Power System Design, Systems Engineering, Power Conversion, Power Conditioning
Boston, Massachusetts, United States · On-site
$115k–$150k/yr
Who We Are We are a rapidly growing embodied AI company revolutionizing human labor. Leveraging cutting-edge robotics and advanced artificial intelligence, we develop transformative technologies that redefine how work is…
Skills: Electrical System Design, Circuit Design, Control Systems, Wiring Harnesses, Sensor Integration
Boston, Massachusetts, United States · On-site
$125k–$160k/yr
Who We Are We are a rapidly growing embodied AI company revolutionizing human labor. Leveraging cutting-edge robotics and advanced artificial intelligence, we develop transformative technologies that redefine how work is…
Skills: Mechanical Design, Robotics, 3D Modeling, Technical Drawing, CAD
Boston, Massachusetts, United States · On-site
General Summary: The Environmental Health and Safety (HS) Manager will work under the Director of OEHS. The HS Manager will perform complex safety and health program work. Work involves developing safety policies and pro…
Skills: Fire Safety Management, Industrial Hygiene, Indoor Air Quality Assessment, Hazard Inspection, Accident Investigation
Marlborough, Massachusetts, United States · Hybrid
$122k–$195k/yr
The Role Moderna is seeking an Individual to support the implementation, optimization, and lifecycle management of process automation systems supporting Individualized Neoantigen Therapies (INT) across Moderna’s manufact…
Skills: Emerson DeltaV DCS, PLC Programming, SCADA Systems, Robotics, VMware
Somerville, Massachusetts, United States · On-site
About AgZen: AgZen is a fast-growing precision agriculture company headquartered in Somerville, MA, built on MIT research and focused on one problem: making crop spraying more efficient. Our flagship product, RealCoverag…
Skills: Manufacturing Engineering, CAD Software, SolidWorks, GD&T, DFM/DFA
North Reading, Massachusetts, United States · On-site
$199k–$269k/yr
Amazon Robotics is revolutionizing warehouse automation at unprecedented scale. We are looking for a technical lead to own the whole-body planning, control, and optimization stack for the Phoenix mobile manipulation robo…
Skills: Whole-body planning, Motion planning, Trajectory optimization, Python, C++
Brockton, Massachusetts, United States · On-site
$50/hr–$72/hr
POSITION SUMMARY: Assures the timely and accurate administration of medications and IV solutions to patients pursuant to a therapeutically valid prescribed order and in accordance with all state and federal regulations a…
Skills: Clinical Pharmacy, Medication Administration, IV Solutions, Pyxis, Meditech
Great Barrington, Massachusetts, United States · On-site
At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, ev…
Skills: Blood Collection, Venipuncture, Specimen Processing, Accessioning, Centrifugation
Boston, Massachusetts, United States · Hybrid
$199k–$236k/yr
Position Overview Bicara Therapeutics is seeking an Associate Director, Global Scientific Communications, who will lead the development and execution of global scientific communication plans across key assets. This role …
Skills: Scientific Communication Planning, Publication Management, Medical Writing, Cross-Functional Leadership, Vendor Management
Boston, Massachusetts, United States · On-site
$194k–$291k/yr
This is what you will do: As part of the Hematology and Nephrology (Hem/Neph) U.S. commercial team, the Director, U.S. HCP Marketing Strategy, HSCT-TMA will report to the marketing lead aHUS/TMA and partners with the US …
Skills: HCP Marketing Strategy, Product Launch Execution, Rare Disease Marketing, Brand Planning, Market Research
Boston, Massachusetts, United States · On-site
$50/hr–$100/hr
When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives. This position is responsible in consultation with the Clinical Trials Office (CTO) Manager for providing an…
Skills: Contract Negotiation, Legal Review, Healthcare Law, Regulatory Compliance, Drafting Agreements
Cambridge, Massachusetts, United States · Hybrid
$204k–$380k/yr
Band Level 6 Job Description Summary #LI-Hybrid Location: Cambridge, United States or Basel, Switzerland (see separate posting) Ready to shape the future of innovation at Novartis? As a Patent Attorney, you will play a p…
Skills: Patent Prosecution, Intellectual Property Strategy, Freedom To Operate Analysis, Patent Portfolio Management, Legal Opinion Drafting
Boston, Massachusetts, United States · On-site
$138k–$224k/yr
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headqua…
Skills: Immunology, CAR-T Biology, In Vivo Study Design, In Vitro Assay Development, LNP Delivery
Cambridge, Massachusetts, United States · Hybrid
$204k–$380k/yr
Job Description Summary #LI-Hybrid Location: Cambridge, United States or Basel, Switzerland (see separate posting) Ready to shape the future of innovation at Novartis? As a Patent Attorney, you will play a pivotal role i…
Skills: Patent Prosecution, Intellectual Property Strategy, Freedom To Operate Analysis, Patent Drafting, Chemistry Expertise
Boston, Massachusetts, United States · On-site
$90k–$118k/yr
Site: The Spaulding Rehabilitation Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance…
Skills: Patient Assessment, Physical Therapy Treatment Planning, Manual Exercises, Case Management, Medical Terminology
Cambridge, Massachusetts, United States · On-site
$139k–$283k/yr
Band Level 5 Job Description Summary We are seeking a highly motivated and experienced scientist to lead a Human Genetics laboratory. You will drive the translation of human genetic insights into actionable biological hy…
Skills: Analytical Thinking, Chemical Biology, Clinical Research, Clinical Trials, Collaboration
Cambridge, Massachusetts, United States • Hybrid
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Lead the scientific strategy for ADC payload selection, linker design, and conjugation approaches to advance next-generation targeted therapeutics. Collaborate with cross-functional teams to integrate biology-driven insights and evaluate novel platform innovations for oncology programs.
Requires a Ph.D. in a relevant scientific discipline and 5-10 years of industry experience in ADC discovery or oncology drug discovery. Must possess deep expertise in payload mechanisms, linker stability, and the ability to lead cross-functional scientific discussions.
Lead scientific strategy for ADC payload selection, linker design, conjugation approaches, and related platform innovations
Apply deep expertise across payload classes, mechanisms of action, potency, resistance biology, bystander activity, and tolerability to guide program design
Partner with chemistry, biology, protein engineering, pharmacology, translational sciences, and CMC teams to advance next-generation ADCs
Evaluate and prioritize novel payloads, linker technologies, and conjugation approaches for internal programs and external opportunities
Provide biology-driven insights into payload mechanism of action, tumor context, therapeutic index, and combination strategies
Design and guide experimental strategies to assess ADC activity, selectivity, resistance mechanisms, linker stability, and payload-related pharmacology
Contribute to next-generation ADC platform strategy, including differentiated payload-linker concepts and biology-aligned ADC design
Represent payload/linker expertise in cross-functional project teams, governance discussions, and external collaborations
Monitor scientific, clinical, competitive, and IP landscapes related to ADC payloads, linkers, and emerging targeted modalities
Mentor scientists and contribute to a collaborative, high-performing research environment
Ph.D. in cancer biology, pharmacology, chemical biology, biochemistry, medicinal chemistry, bioengineering, or related discipline
5–10 years of relevant industry experience in ADC discovery, targeted therapeutics, or oncology drug discovery
Extensive expertise in ADC payloads, including mechanism of action, potency, resistance biology, and therapeutic index considerations
Strong knowledge of linker and conjugation technologies, including stability, release mechanisms, site-specific conjugation, and developability
Deep understanding of ADC biology including tumor targeting, internalization, trafficking, payload release, bystander effects, and pharmacology
Demonstrated ability to integrate biology, chemistry, and translational data into actionable program strategies
Proven experience leading cross-functional scientific discussions and influencing program direction
Strong communication, collaboration, and leadership skills
The salary for this position is expected to range between $152,600-$283,400 USD Annual per year.
The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Novartis is an innovative medicines company. Every day, working to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 250 million people worldwide. Find out more at https://www.novartis.com See our community guidelines: https://go.novartis.social/3Nboxki
Offices: Novartis Campus, Basel, Baselstadt 4002, CH · One Health Plaza, East Hanover, NJ 07936, US · Calle 93B S-31, Bogota, Bogota, D.C. 110541, CO · Merrion Road, Dublin, County Dublin, IE · Na Pankraci 1724/129, Prague, Prague 140 00, CZ
Based on 4304 listings with disclosed salaries, most science & research jobs in Massachusetts pay between $90k–$238k per year. Individual offers vary with seniority, company size, and specialization.
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