Science & Research Jobs in California (Now Hiring) — 18,489 open — Page 448
Arrowhead Pharmaceuticals
Senior Manager, Clinical and PV Quality Assurance (Inspection Readiness and Management)
Pasadena, California, United States · On-site
$145k–$170k/yr
Senior+
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA…
Compensation range for the role is listed above. Applicable salary ranges may differ across markets. Actual pay will be determined based on experience and other job-related factors permitted by law. As a part of the comp…
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Company Description We are proud to inform you that this position is eligible for our Student Loan Assistance Program. You may receive up to $9,600 which will be applied directly to your student loan account*. *This bene…
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA…
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Rancho Murieta, California, United States · On-site
$60k–$80k/yr
Mid level
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Pharmaceutical SalesTerritory Representative - Primary Care (Entry Level-Specialty) Are you looking for a lucrative career where you can make a big difference in the health of others. Does a patient-focused, innovation-d…
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Mountain View, California, United States · On-site
$147k–$211k/yr
Mid level$26M raised
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Mountain View, California, United States · On-site
$207k–$301k/yr
Senior$26M raised
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Supplier Development Engineering Manager, Mechanical Operations
Mountain View, California, United States · On-site
$171k–$248k/yr
Senior+$26M raised
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Skills: Surface Finishing, CNC, 3D Printing, PVD, Metal Injection Molding
Senior Manager, Clinical and PV Quality Assurance (Inspection Readiness and Management)
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$145k–$170k/yr
Full-time
bachelor degree, postgraduate degree
Competitive Salaries, Excellent Benefit Package
Posted 24d ago
~40 hrs/week
Responsibilities
Lead the global Clinical and Pharmacovigilance Quality Assurance programs, focusing on inspection readiness and managing regulatory inspections from agencies like the FDA and EMA. Oversee risk-based internal and partner audits to ensure compliance with GxP regulations and drive continuous improvement initiatives.
Requirements
Requires a Bachelor's degree in life sciences or a related field with at least eight years of pharmaceutical industry experience, including five years in leadership. Must possess deep knowledge of GCP/GVP regulations, ICH guidelines, and experience with electronic quality management systems.
Full job description
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Provide strategic leadership for the company's global Clinical and Pharmacovigilance (GCP/GVP) Quality Assurance programs by overseeing inspection readiness, regulatory inspection management, internal quality audits, and partner audit activities. Lead the Inspection Readiness and Management Program, serving as the primary Inspection Lead responsible for planning, hosting, facilitating, and directing regulatory inspections conducted by the FDA (BIMO), MHRA, PMDA, EMA, and other global Health Authorities, including Pharmacovigilance post-marketing inspections. Lead and execute a risk-based internal GCP/GVP audit program and oversee partner and alliance audits to evaluate compliance with applicable regulations, industry standards, and company procedures.
Partner with executive leadership and cross-functional stakeholders to maintain a continuous state of inspection readiness, ensure effective execution of regulatory inspections and audits, foster high-quality regulatory interactions, and drive timely responses to inspection and audit observations, CAPAs, and continuous improvement initiatives. Provide strategic leadership across Clinical Operations, Pharmacovigilance, Regulatory Affairs, Medical Affairs, Biometrics, Data Management, Quality, and external partners to promote sustainable compliance, operational excellence, and inspection success throughout the product development lifecycle.
This role is based in Pasadena with an expectation to be in office 5 days a week.
Responsibilities
Own the global GCP/GVP Inspection Readiness Program and establish governance that maintains continuous inspection readiness.
Serve as the primary Inspection Lead and Host for FDA BIMO, MHRA, PMDA, EMA, and other Health Authority inspections, including PV post-marketing surveillance inspections.
Lead all inspection planning activities including scope, logistics, agendas, inspection rooms, virtual inspection platforms, document management, and inspection communication plans.
Facilitate and direct inspection management activities before, during, and after inspections, ensuring alignment across stakeholders and executive leadership.
Chair daily inspection meetings, back room activities, issue escalation, risk assessments, and executive debriefs throughout inspections.
Lead preparation of SMEs and executives through mock inspections, interview coaching, inspection simulations, and readiness assessments.
Oversee regulatory document requests, quality review of submissions, and consistency of inspection responses.
Lead cross-functional development of responses to Form FDA 483 observations and equivalent findings, CAPAs, effectiveness checks, and regulatory commitments.
Provide strategic oversight of CROs, vendors, and business partners to ensure inspection readiness and inspection support.
Develop and present inspection readiness dashboards, KPIs, risk metrics, and trend analyses to Quality and Executive Leadership.
Lead implementation of new global regulatory expectations including ICH E6(R3), FDA, EMA, MHRA, PMDA, and GVP guidance.
Drive continuous improvement initiatives that strengthen inspection readiness, quality systems, and operational excellence.
Develop, implement, and lead a risk-based GCP and Pharmacovigilance (GVP) internal audit program, including planning, conducting, reporting, and overseeing corrective and preventive actions (CAPAs) to assess compliance, identify risks, and drive continuous quality improvement.
Lead and host partner, alliance, licensing, and due diligence audits by coordinating cross-functional stakeholders, managing audit planning and execution, facilitating auditor interactions, and ensuring timely responses to audit observations, commitments, and CAPAs.
Requirements
Bachelor's degree in life sciences, pharmacy, chemistry, or related field.
Minimum of eight (8) years of experience in the regulated pharmaceutical and/or biotechnology industry, in which at least five (5) of those years were in a leadership position with increasing levels of responsibility.
Full knowledge of GxP regulations, including GCP/GVP (FDA, EU, etc.), ICH guidelines, and ISO standards.
Demonstrated skills in the areas of project management, organization, and execution as well as priority setting.
Highly motivated, strategic thinker with a focus on continuous improvement and innovation, who endeavors to anticipate and resolve problems.
Excellent communication, interpersonal, and leadership skills, with the ability to work with a diverse range of professionals and influence stakeholders at all levels.
Previous experience with the use of electronic document / quality management systems (EMDS / EQMS).
Business travel approx. 25-30%
Preferred
Advanced degree in life science preferred
California pay range
$145,000—$170,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
How much do Science & Research jobs in California pay?
Based on 11656 listings with disclosed salaries, most science & research jobs in California pay between $103k–$250k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in California right now?
There are currently 18,489 open science & research positions in California listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in California?
Companies currently hiring include Applied Materials, Northrop Grumman, Apple, Google, Kaiser Permanente Oakland Medical Center, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in California?
Yes — 3921 of the 18489 open science & research positions offer remote or hybrid work (1006 remote, 2915 hybrid).
How do I apply for Science & Research jobs in California?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
