About the Role The Director, Early Development - Clinical Sciences will create early development clinical plans, program outlines, study designs and clinical study essential documents. This individual will be accountable…
About the Role Join us in advancing our pipeline to address a number of diseases across therapeutic categories including eye care, dermatology, and other diseases with high unmet needs. This role will be focused on the d…
Skills: Clinical development, Clinical trial protocols, Drug development, Biostatistics, Data analysis
Your Journey to Success: As our Senior Project Manager / Customer Success Manager, you'll own the end-to-end client experience for a portfolio of 20–30 MFour Data Research accounts — you're the person your clients count …
Skills: Client management, Quantitative research, Data analysis, Questionnaire design, SaaS
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less in…
Skills: Medical affairs, Clinical research, Electrophysiology, Strategic thinking, Evidence generation
Senior Mechanical Engineer, Thermal Protection Systems
Irvine, California, United States · On-site
$130k–$180k/yr
Senior$2M raised
About Canopy Aerospace & Defense Canopy A&D is built to accelerate the future of advanced materials for space, defense, and maritime systems. Canopy delivers specialized materials and components that carry customers from…
EWOR is launching cutting-edge new initiatives, and we are looking for exceptional operators and builders to join our new department. We are backed and led by serial entrepreneurs, including Paul Müller (founder of Adjus…
Senior Specialist, International Regulatory Affairs THV
Irvine, California, United States · On-site
$92k–$130k/yr
Senior
Make a meaningful difference to patients around the world. From design to production, our Regulatory Affairs teams help guide our innovative technologies through complex domestic and international regulatory environments…
Skills: Regulatory affairs, Medical devices, Regulatory submissions, Compliance, Product development
A Day in Your Life at MKS: MKS Systems Irvine is growing rapidly through strategic investments in the development and fabrication of advanced optics, opto-mechanical assemblies, fiber optic modules, laser systems, photon…
Hi Tarsan! Thanks for your interest in this position. Please review the details and if role and if it's something that could match your career goals, connect with your current manager and HRBP to discuss if your experien…
About the Role The Director, Toxicology Translational Science will serve as a scientific and strategic leader driving team and pipeline development at Tarsus, leveraging expertise in toxicology, safety pharmacology, and …
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Employment Type: Salaried Work Arrangement: Remote Position Summary: The Manager of Customer Quality is responsible for focus on Customer Experience & "Moments that Matter" for Ventura Foods customers. Responsible for pr…
Benefits: 401(k) 401(k) matching Bonus based on performance Company parties Dental insurance Health insurance Paid time off Training & development Vision insurance BridgeMed Solutions, Inc is seeking a Entry Level Engine…
Skills: Medical device manufacturing, Project management, Regulatory compliance, FDA regulations, ISO standards
Principal Engineer, Process Development (Lasers & Optics)
Irvine, California, United States · On-site
$121k–$171k/yr
Senior
Imagine how your ideas and expertise can change a patient’s life. Our Global Operations & Quality team plays a central part in ensuring our products are delivered to patients with cardiovascular disease. You’ll partner c…
Skills: Laser processing, Optical systems integration, Process development, Medical device manufacturing, Mechanical engineering
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less in…
Skills: Business acumen, Communication, Financial acumen, Statistical software, CAD
A Day in Your Life at MKS: As an Optical Coater at MKS, you will partner with the engineering and cleaning team to perform coating operations on parts, materials, and components, while documenting results. In this role, …
Skills: Coating operations, Thin film deposition, Vacuum systems, Spectroscopy, Inspection
Open Rank Physicist - New Grads Welcome (Irvine, CA)
Irvine, California, United States · On-site
$196k–$380k/yr
Senior$10M raised
Open Rank Physicist – Radiation Oncology (Orange County) (Exempt) (Two positions available) Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cance…
Skills: Radiation Oncology, Medical Physics, Dose Calculations, Plan Optimization, Quality Assurance
Senior Technical Writer - Labeling content and artwork development ( Medical Devices) - On-site
Irvine, California, United States · On-site
$85k–$127k/yr
Mid level$18B raised
We anticipate the application window for this opening will close on - 26 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore heal…
Imagine how your ideas and expertise can change a patient’s life. We generate extensive clinical evidence to demonstrate the effectiveness and safety of our innovations and how our products transform patients’ lives. As …
Skills: Clinical data management, Clinical research, EDC systems, Project management, Data analysis
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
$203k–$285k/yr
Full-time
postgraduate degree
Health insurance, Dental insurance, Vision insurance, Paid time off, Stock equity, Bonus
Posted 15h ago
~40 hrs/week
Responsibilities
The Director will lead cross-functional study teams to create early development clinical plans, study designs, and essential clinical documents. They are responsible for driving operational excellence, interpreting clinical data, and engaging with internal and external stakeholders to ensure scientific rigor.
Requirements
Candidates must hold an advanced degree in sciences such as PharmD, MD, or PhD and possess at least 10 years of biotech or pharmaceutical clinical development experience. A minimum of 8 years in clinical trial leadership is required, along with expertise in GCPs, SOPs, and regulatory compliance.
Full job description
About the Role
The Director, Early Development - Clinical Sciences will create early development clinical plans, program outlines, study designs and clinical study essential documents. This individual will be accountable for leading the cross-functional Study Teams to meet study deliverables and represent clinical development in core team and investigator meetings as needed.
This role will collaborate closely with cross-functional teams such as Clinical Operations, Regulatory Affairs, Medical Affairs, CMC, Finance and Legal to drive efficient and scientifically rigorous early development clinical work.
Let’s talk about some of the key responsibilities of the role:
Maintains direct ownership of early development clinical deliverables, actively contributing to protocol development, document authoring, data review, study-level problem solving and execution decisions to ensure scientific rigor and operational excellence.
Shape clinical plans including timelines, budgets and oversight of clinical teams.
Author and critically review key clinical and regulatory documents, including protocols, SAPs, CSRs, IBs and clinical value dossiers, ensuring scientific rigor, regulatory alignment and quality execution.
Lead and oversees the training of study investigators on protocol and on clinical trial procedures.
Conduct research to develop foundational education material to inform the early development program strategies.
Interpret clinical data and support data-driven decisions.
Serve as program lead on early development Core teams, investigator meetings and scientific advisory boards.
Engage with internal and external stakeholders, including KOLs and regulators.
Exhibits and fosters key leadership competencies, including an innovative mindset, strong business acumen, an outcome-driven orientation, and a commitment to growing and expanding the capabilities and capacity of the team.
Collaborate with Clinical Operations, Regulatory Affairs, Translational Sciences, Biostatistics, Medical Affairs and others to ensure robust trial design, scientific and operational alignment and execution .
Factors for Success:
Advanced degree in sciences (e.g. PharmD, MD, PhD) with deep experience in early clinical development
Experience in ophthalmology is preferred; dermatology or infectious diseases a plus.
Minimum of 10 years of biotech/pharmaceutical clinical development experience, with a minimum of 8 years leadership in clinical trial management experience required
Established leadership track record with evidence of excellent performance-based people management experience, problem solving, collaboration, cross functional leadership and effective communication skills.
Expertise with SOPs, GCPs and regulatory and compliance guidelines for clinical trials.
Must be willing to be “hands on” and delve into details
Leadership Competencies - This role requires mastery of the Tarsus Leadership Competencies for Leading People, including:
Decision Making - Demonstrates strong decision-making by applying structured analysis to complex challenges, balancing competing priorities and long-term impacts while engaging stakeholders and driving solutions aligned with organizational goals.
Collaboration and Team Building - Promotes collaboration by aligning diverse teams around shared goals, fostering healthy debate to advance outcomes, and building strong networks that strengthen organizational effectiveness and cross-team learning.
Outcome Driven - Demonstrates strong outcomes focus by aligning teams around shared priorities, proactively addressing risks and dependencies, and driving cross-functional accountability to sustain progress and deliver results.
Empowering Others - Fosters empowerment by aligning authority with accountability, developing leaders’ decision-making capability, and creating systems that support performance and growth.
Emotional Intelligence - Foster trust and psychological safety, navigating complex interpersonal dynamics with compassion and accountability, and adapting leadership style to support others while maintaining composure under pressure.
Few Other Details Worth Mentioning:
The position will be based in our beautiful Irvine office, complete with onsite gym, pool, snacks, drinks, and occasional catered meals. We provide a hybrid work environment. Remote work is an option.
We are passionate about our culture! Our Tarsans live our values of commitment to patients, empowerment to champion innovation, and teamwork to amplify impact!
This position reports directly to our SVP, Development
Some travel may be required – up to 30%
At Tarsus, we understand the importance of attracting and retaining top talent. The expected base pay range for this position is $203,200 - $284,600 plus bonus, stock equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. Our benefits include health, dental and vision insurance benefits to ensure your well-being. We believe in work-life balance and offer generous paid time off, including vacation, holidays, and personal days. For more details regarding Tarsus benefits, please visit: https://eb.alliant.com/26tarsusbenefitssnapshot.
#LI-Remote
Tarsus Pharmaceuticals, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.
Tarsus (NASDAQ:TARS) is a biopharmaceutical company that applies proven science and new technology to revolutionize treatment for patients, starting with eye care.
Offices: 15440 Laguna Canyon Rd, Irvine, California 92618, US
How many Science & Research jobs are open in Irvine, CA right now?
There are currently 503 open science & research positions in Irvine, CA listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Irvine, CA?
Companies currently hiring include UCI Health, Edwards Lifesciences, Allergan, FieldAI, Tarsus Pharmaceuticals, Inc., among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Irvine, CA?
Yes — 112 of the 503 open science & research positions offer remote or hybrid work (32 remote, 80 hybrid).
How do I apply for Science & Research jobs in Irvine, CA?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.