Science & Research Jobs in Irvine, CA (Now Hiring) — 503 open

Director, Early Development - Clinical Sciences

Irvine, California, United States · Hybrid

$203k–$285k/yr

Senior+$711M raised

About the Role The Director, Early Development - Clinical Sciences will create early development clinical plans, program outlines, study designs and clinical study essential documents. This individual will be accountable…

Skills: Clinical development, Clinical trial management, Protocol development, Regulatory affairs, Data interpretation

Associate Director, Clinical Sciences

Irvine, California, United States · Hybrid

$165k–$231k/yr

Senior+$711M raised

About the Role Join us in advancing our pipeline to address a number of diseases across therapeutic categories including eye care, dermatology, and other diseases with high unmet needs. This role will be focused on the d…

Skills: Clinical development, Clinical trial protocols, Drug development, Biostatistics, Data analysis

Customer Success Manager

Irvine, California, United States · Hybrid

$75k–$90k/yr

Mid level$5M raised

Your Journey to Success: As our Senior Project Manager / Customer Success Manager, you'll own the end-to-end client experience for a portfolio of 20–30 MFour Data Research accounts — you're the person your clients count …

Skills: Client management, Quantitative research, Data analysis, Questionnaire design, SaaS

Director, Medical Excellence, Electrophysiology

Haifa, Haifa, Israel · Hybrid

$164k–$306k/yr

Senior+

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less in…

Skills: Medical affairs, Clinical research, Electrophysiology, Strategic thinking, Evidence generation

Senior Mechanical Engineer, Thermal Protection Systems

Irvine, California, United States · On-site

$130k–$180k/yr

Senior$2M raised

About Canopy Aerospace & Defense Canopy A&D is built to accelerate the future of advanced materials for space, defense, and maritime systems. Canopy delivers specialized materials and components that carry customers from…

Skills: Thermal protection systems, Mechanical engineering, CAD modeling, GD&T, Materials science

MedTech Behavioral Scientist (100 % remote) (m/f/d)

Irvine, California, United States · Remote Solely

Senior$38M raised

EWOR is launching cutting-edge new initiatives, and we are looking for exceptional operators and builders to join our new department. We are backed and led by serial entrepreneurs, including Paul Müller (founder of Adjus…

Skills: Behavioral science, MedTech, Strategic planning, Product development, Project management

Senior Specialist, International Regulatory Affairs THV

Irvine, California, United States · On-site

$92k–$130k/yr

Senior

Make a meaningful difference to patients around the world. From design to production, our Regulatory Affairs teams help guide our innovative technologies through complex domestic and international regulatory environments…

Skills: Regulatory affairs, Medical devices, Regulatory submissions, Compliance, Product development

Principal Measurement & Test Engineer

Irvine, California, United States · On-site

$115k–$180k/yr

Senior+$5.0B raised

A Day in Your Life at MKS: MKS Systems Irvine is growing rapidly through strategic investments in the development and fabrication of advanced optics, opto-mechanical assemblies, fiber optic modules, laser systems, photon…

Skills: Optical engineering, Metrology, Calibration methodologies, Uncertainty analysis, Optical characterization

Director, Toxicology

Irvine, California, United States · Remote OK

$188k–$264k/yr

Senior+$711M raised

Hi Tarsan! Thanks for your interest in this position. Please review the details and if role and if it's something that could match your career goals, connect with your current manager and HRBP to discuss if your experien…

Skills: Toxicology, Safety Pharmacology, Translational Science, GLP Compliance, CRO Management

Director, Toxicology

Irvine, California, United States · Hybrid

$188k–$264k/yr

Senior+$711M raised

About the Role The Director, Toxicology Translational Science will serve as a scientific and strategic leader driving team and pipeline development at Tarsus, leveraging expertise in toxicology, safety pharmacology, and …

Skills: Toxicology, Safety pharmacology, Translational science, GLP compliance, Regulatory submissions

Associate Director, Regulatory Affairs Advertising & Promotion - Eye Care (Hybrid)

Irvine, California, United States · Hybrid

$142k–$269k/yr

Senior+

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…

Skills: Regulatory affairs, Advertising and promotion, Strategic planning, Cross-functional leadership, Regulatory compliance

Customer Solutions Manager- Quality

Irvine, California, United States · Remote OK

$109k–$172k/yr

Senior

Employment Type: Salaried Work Arrangement: Remote Position Summary: The Manager of Customer Quality is responsible for focus on Customer Experience & "Moments that Matter" for Ventura Foods customers. Responsible for pr…

Skills: Quality management, Food safety, Complaint handling, Data analysis, Customer experience

Entry Level Engineer

Irvine, California, United States · On-site

$23/hr–$26/hr

Entry level

Benefits: 401(k) 401(k) matching Bonus based on performance Company parties Dental insurance Health insurance Paid time off Training & development Vision insurance BridgeMed Solutions, Inc is seeking a Entry Level Engine…

Skills: Medical device manufacturing, Project management, Regulatory compliance, FDA regulations, ISO standards

Principal Engineer, Process Development (Lasers & Optics)

Irvine, California, United States · On-site

$121k–$171k/yr

Senior

Imagine how your ideas and expertise can change a patient’s life. Our Global Operations & Quality team plays a central part in ensuring our products are delivered to patients with cardiovascular disease. You’ll partner c…

Skills: Laser processing, Optical systems integration, Process development, Medical device manufacturing, Mechanical engineering

NPI & LCM Principal Engineer | Irvine, CA

Irvine, California, United States · Hybrid

$102k–$177k/yr

Senior

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less in…

Skills: Business acumen, Communication, Financial acumen, Statistical software, CAD

Optics Coater 3 - Second Shift

Irvine, California, United States · On-site

$22/hr–$37/hr

Entry level$5.0B raised

A Day in Your Life at MKS: As an Optical Coater at MKS, you will partner with the engineering and cleaning team to perform coating operations on parts, materials, and components, while documenting results. In this role, …

Skills: Coating operations, Thin film deposition, Vacuum systems, Spectroscopy, Inspection

Open Rank Physicist - New Grads Welcome (Irvine, CA)

Irvine, California, United States · On-site

$196k–$380k/yr

Senior$10M raised

Open Rank Physicist – Radiation Oncology (Orange County) (Exempt) (Two positions available) Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cance…

Skills: Radiation Oncology, Medical Physics, Dose Calculations, Plan Optimization, Quality Assurance

Senior Technical Writer - Labeling content and artwork development ( Medical Devices) - On-site

Irvine, California, United States · On-site

$85k–$127k/yr

Mid level$18B raised

We anticipate the application window for this opening will close on - 26 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore heal…

Skills: Technical writing, Labeling content development, Artwork development, Medical device regulations, Regulatory compliance

Senior Specialist, Regulatory Affairs

Irvine, California, United States · On-site

$95k/yr

Mid level$342M raised

Job DetailsJob Location: Irvine, CA 92618Position Type: Full TimeEducation Level: 4 Year DegreeSalary Range: $95,000.00 - $95,000.00 SalaryJob Category: QA - Quality ControlJob Title: Senior Specialist, Regulatory Affair…

Skills: Regulatory Affairs, Medical Device Regulations, Quality Systems, Technical Writing, Project Management

Senior Analyst, Clinical Data Management

Irvine, California, United States · On-site

$108k–$153k/yr

Senior

Imagine how your ideas and expertise can change a patient’s life. We generate extensive clinical evidence to demonstrate the effectiveness and safety of our innovations and how our products transform patients’ lives. As …

Skills: Clinical data management, Clinical research, EDC systems, Project management, Data analysis

Frequently asked questions

How many Science & Research jobs are open in Irvine, CA right now?

There are currently 503 open science & research positions in Irvine, CA listed on Clera. New openings are added daily as companies post roles.

Which companies are hiring for Science & Research roles in Irvine, CA?

Companies currently hiring include UCI Health, Edwards Lifesciences, Allergan, FieldAI, Tarsus Pharmaceuticals, Inc., among others. Browse the listings above to see every active employer.

Are there remote or hybrid Science & Research jobs in Irvine, CA?

Yes — 112 of the 503 open science & research positions offer remote or hybrid work (32 remote, 80 hybrid).

How do I apply for Science & Research jobs in Irvine, CA?

Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.