Principal Research Scientist I, Multispecifics Engineering
Worcester, Massachusetts, United States · On-site
$125k–$237k/yr
Senior+
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Burlington, Massachusetts, United States · On-site
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Scientist I, In Vitro Technologies - Discovery Biotherapeutics
Worcester, Massachusetts, United States · On-site
$75k–$143k/yr
Senior
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Wilmington, Massachusetts, United States · On-site
$93k–$176k/yr
Mid level
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Wilmington, Massachusetts, United States · On-site
$93k–$176k/yr
Mid level
About This Role We are seeking an experienced and highly skilled Systems Engineer with an Electrical or Software/Firmware Engineering background to join our team. We believe people should love what they do – in this role…
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$125k–$237k/yr
Full-time
postgraduate degree
Paid Time Off, Vacation, Holidays, Sick Leave, Medical Insurance, Dental Insurance
Posted 42d ago
~40 hrs/week
Responsibilities
Lead the design, engineering, and production of multispecific biologics across various therapeutic areas. Coordinate activities from hit generation to candidate nomination while serving as a technical expert in cross-functional teams.
Requirements
Requires a PhD or MS in Biochemistry or related fields with extensive experience in multispecific or antibody engineering. Candidates must possess strong skills in protein expression, purification, and the ability to manage both projects and direct reports.
Full job description
Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn,Facebook, Instagram, X and YouTube.
Job Description
The Multispecifics Engineering group at AbbVie is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting Discovery Biotherapeutics. This position will impact projects through engineering, production, and characterization of multispecific biopharmaceutical products. The ideal candidate should have extensive experience with biologics and multispecifics production platforms, analytical characterization, and a proven track record implementing multispecific engineering and production strategies to advance early- and late-stage discovery programs. The ideal candidate will also have people and project management experience. The applicant should be an enthusiastic, creative scientist who will make tangible contributions to the pipeline.
Key responsibilities:
Responsible for design, engineering, and production of multispecific biologics supporting multiple therapeutic areas
Serve as a Multispecifics Engineering representative in cross-functional teams including the Therapeutic Area, Discovery Biotherapeutics, and Development Sciences, providing project updates, analysis, and advice; recognized expert in multispecific design and production
Serve as the Biologics Lead on projects to coordinate activities and transitions from hit generation through candidate nomination
Identify and solve technical problems independently, conceive and implement innovative research ideas
Ensure consistency and quality of technical reports
Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents
Qualifications
PhD or MS degree in Biochemistry, Biochemical engineering or related disciplines
6+ (PhD) or 12+ (MS) years of experience in multispecific engineering or antibody engineering
Experience with protein, biologics, fragments, or multispecifics (e.g. bispecifics, trispecifics, bispecific protein fusions) design, expression and purification
In-depth knowledge of the multispecific landscape, trends in design, and application across therapeutic areas including immunology, oncology, and neuroscience
Ability to recognize emerging areas of interest in multispecific engineering, antibody engineering, and related fields, and make connections between research ideas to advance platforms and programs
Excellent organizational skills and the ability to manage multiple projects simultaneously
Team player with the ability to operate in a fast-paced multi-disciplinary environment
Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong can-do attitude
Preferred qualifications:
Experience with sequence analysis tools (Vector NTI, Geneious, Genedata)
Experience with mass spectrometry analysis and software (Protein Metrics)
Experience with CRO coordination for production
Expert understanding of current state of protein expression/separation/analytical technologies
Extensive knowledge of biologic pipeline progression from exploratory through candidate nomination with program management experience preferred
Experience managing direct reports and providing performance evaluations and development opportunities
Recognized in the scientific community through a sustained record of peer-reviewed publications and patents preferred
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
Allergan is now part of AbbVie.
AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.
For more information about AbbVie, please visit us at www.abbvie.com. Follow @AbbVie on LinkedIn for future updates.
Offices: Allergan plc, Dublin, Coolock D17 E400, IE · Morris Corporate Center III, 400 Interpace Parkway, Parsippany, NJ 07054, US · Parkway, Marlow, England SL7 1YL, GB · 301 W Howard Ln, Austin, TX 78753, US · 8301 Mars Dr, Hewitt, TX 76712, US
Health CareBiopharmaEducationBiotechnologyMedicalUniversitiesPharmaceutical
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