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Responsible for executing and monitoring the medical aspects of oncology clinical trials, including the creation of protocols, investigator brochures, and clinical modules. The role involves overseeing data review, safety monitoring, and leading the development of clinical study reports and publications.
Requires a BS in life sciences (PhD, RN, PharmD, or MS preferred) with at least 15 years of pharmaceutical industry experience and 4 years in oncology. Candidates must have a strong background in clinical science, data interpretation, and experience leading cross-functional trial teams.
Introduction:
Xencor is a public, clinical-stage biopharmaceutical company located in the Los Angeles area (Pasadena) and in San Diego. Our focus is developing high-potential XmAb® bispecific T-cell engagers and additional engineered drug candidates that leverage our differentiated technology platforms, and we are advancing our pipeline toward clinical proof-of-concept decisions. Our goal is to create high-impact therapeutics for patients with cancer and other serious diseases. More than 20 XmAb drug candidates engineered with our technology are in clinical development, and three XmAb medicines have been marketed by partners. For more information, please visit www.xencor.com. We have an excellent opportunity for a Sr. Director, Clinical Science (Oncology), to join our team.
This is a hybrid position that can be based out of our San Diego or Pasadena, CA. locations.
Summary:
Responsible for facilitating successful and timely initiation and completion of the Company’s clinical development programs by executing and monitoring medical aspects of selected clinical trials.
Primary Responsibilities:
Education/Experience/Skills:
Position requires a BS degree in life sciences; PhD, RN, PharmD or MS preferred and a minimum of 15 years of directly relevant pharmaceutical industry experience in clinical development and a minimum of 4 years’ experience of focus in assigned therapeutic area. Experience as a clinical scientist responsible for data review, safety monitoring, protocol development, supporting data analyses, interpretation and publications also required, as well as clinical research experience in area of focus, strong, hands-on working knowledge of drug development, and experience working on cross functional clinical trial teams and liaising with study investigators. Prior experience with translational medicine/early phase clinical trials, monoclonal antibody biologics/immunotherapy, and relevant tasks throughout the entire study life cycle, from study concept to database lock and CSR is preferred.
Position also requires:
Occasional travel may be required, including travel between Xencor’s Pasadena and San Diego offices. Work for this position is generally performed at Xencor’s worksite and requires full-time commitment.
Expected Base Salary Range: $247,700 - $309,000
The actual salary will be based on the selected candidate’s qualifications, including skills, competencies, education and experience. Xencor offers a competitive total rewards package including 401k match, healthcare coverage, ESPP and a broad range of other benefits. In addition, this position will be eligible for an annual bonus and equity grant. For more information, please see https://xencor.com/careers/.
Americans with Disabilities Act (ADA) Statement
The Company will provide reasonable accommodations (such as a qualified sign language interpreter or other personal assistance) with the application process upon your request as required to comply with applicable laws. If you have a disability and require assistance in this application process, please contact [email protected].
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. Reasonable Accommodations may be made to enable qualified individuals with disabilities to perform the essential functions.
Equal Employment Opportunity (EEO) Statement
The Company is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender or gender identity, national origin, disability status, protected veteran status or any other characteristic protected by state or federal law.
Xencor does not accept profiles or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by Xencor, implied or otherwise.
Proteins by Design
Designing Proteins. Delivering Medicines. Antibody and protein biotherapeutics are changing the way physicians treat autoimmune diseases, asthma, and cancer. At Xencor, we apply proprietary protein engineering technologies to develop better biotherapeutics – antibodies that target new biological mechanisms and are more potent, safer and longer lasting – to improve patient outcomes and quality of life. Our XmAb antibody engineering technology dramatically augments natural antibody immune functions while maintaining over 99.5% identity to natural antibodies. This combination of new, highly potent activities while maintaining the beneficial drug features and simplicity of natural antibodies allows us to create differentiated drug candidates with potential for breakthrough performance. The XmAb® platform has resulted in a robust pipeline of antibody product candidates, including eight in human clinical trials being developed by Xencor and by pharmaceutical partners. Xencor is also discovering biologics products that improve the performance of old antibody drugs, known as biosuperiors, to benefit patients, ease compliance and help reduce costs.
Offices: 465 N Halstead St, Suite 200, Pasadena, California 91107, US · 12770 High Bluff Drive Unit 260, San Diego, CA 92130-2077, US
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