Cary, North Carolina, United States · Hybrid
$95k–$177k/yr
The Position Data & Analytics Engineer/Senior Data & Analytics Engineer (PI, MQTT and UNS) The Opportunity Welcome to Holly Springs, North Carolina— home to Roche/Genentech's largest-ever investment: a $2B greenfield sta…
Skills: AVEVA PI System, MQTT, Unified Namespace (UNS), Data Pipeline Design, Python
Knightdale, North Carolina, United States · On-site
Voxel is seeking a Control and Automation Engineer to develop our advanced manufacturing equipment and processes. Voxel is a leader in Pulsed Electrochemical Machining (PECM), an advanced manufacturing process used to ma…
Skills: PLC Programming, Structured Text, Python, SQL, Beckhoff TwinCAT
Wilmington, North Carolina, United States · On-site
$70k–$90k/yr
CNC Machining Process Engineer Position Information Position Title: CNC Machining Process Engineer Department: Research & Development Company: Protocase Inc. Location: Wilmington, North Carolina Work Arrangement: On-site…
Skills: CNC Machining, 5-Axis Milling, G-code Programming, CAM Software, Root Cause Analysis
Charlotte, North Carolina, United States · Hybrid
Important Application Submission Information In order to ensure your application is successfully received before the job posting expires, please submit your application by 11:59 PM on Thursday, July 30, 2026 More than a …
Skills: Engineering Theories, Engineering Principles, Researching Engineering Issues, Design Evaluation, Written Communication
Wilson, North Carolina, United States · On-site
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less in…
Skills: Process Engineering, Device Assembly, Aseptic Manufacturing, Commissioning & Qualification, cGMP
Davidson, North Carolina, United States · Hybrid
$90k–$125k/yr
Be a part of our mission! As a world leader in creating comfortable, sustainable, and efficient climate solutions for buildings, homes and transportation, it's our responsibility to put the planet first. For us at Trane …
Skills: Project Management, Embedded Software Development, HVAC Systems, Control Systems, Instrumentation
Raleigh, North Carolina, United States · Remote OK
Location: Remote - North Carolina, United States Job ID: R0125778 Date Posted: 2026-07-24 Company Name: HITACHI ENERGY USA INC Profession (Job Category): Engineering & Science Job Schedule: Full time Remote: Yes Job Desc…
Skills: Construction Management, Substation Installation, Electrical Equipment Installation, Project Coordination, Subcontractor Management
Durham, North Carolina, United States · On-site
Expected Travel: Up to 10% Requisition ID: 14174 About Teleflex Incorporated As a global provider of medical technologies, Teleflex is driven by our purpose to improve the health and quality of people’s lives. Through ou…
Skills: Sustaining Engineering, Medical Device Development, SolidWorks, Design Control, Change Management
Charlotte, North Carolina, United States · Hybrid
SMBC Group is a top-tier global financial group. Headquartered in Tokyo and with a 400-year history, SMBC Group offers a diverse range of financial services, including banking, leasing, securities, credit cards, and cons…
Skills: Quality Engineering Leadership, Fixed Income Product Knowledge, Test Automation Frameworks, QA Governance, Post-Trade Processing
Charlotte, North Carolina, United States · On-site
Overview Our Charlotte, NC office is looking for a Substation Physical Designer with 10+ years of experience to join our Power Delivery team! Responsibilities Responsibilities include, but are not limited to, the design …
Skills: Substation Physical Design, Autodesk, Bentley Products, Technical Drawing, One-line Diagrams
Charlotte, North Carolina, United States · On-site
Founded in 1963 by Don Fessler & George Bowman, Fessler & Bowman, Inc. has grown from a residential flatwork & basement wall contractor to a top 100 Commercial Concrete Contractor recognized across the nation. Keeping cu…
Skills: Project Planning, Scheduling, Project Accounting, Document Control, Procore
Charlotte, North Carolina, United States · On-site
$100k–$120k/yr
Baker Roofing Company – New Construction Senior Estimator The New Construction Senior Estimator prices and sells assigned projects while supporting department-wide development. This role demands accuracy, integrity, and …
Skills: Project Bidding, Plan and Spec Reading, Low-slope Roofing Systems, Take-offs, Contract Negotiation
Stanly County, North Carolina, United States · On-site
$67k–$117k/yr
Agency Dept of Transportation Division State Hwy Administrator - Div of Hwys Job Classification Title Business Systems Analyst II (NS) Position Number 60022476 Grade NC19 About Us It’s the mission of the NC Department of…
Skills: ArcGIS Pro, ArcGIS Online, ArcGIS Survey123, ArcGIS Field Maps, ArcGIS Experience Builder
Stanly, North Carolina, United States · On-site
$41k–$72k/yr
Agency Dept of Transportation Division State Hwy Administrator - Div of Hwys Job Classification Title Electronics Technician I (S) Position Number 60021458 Grade NC09 About Us It’s the mission of the NC Department of Tra…
Skills: Electronics Repair, Traffic Control Systems, Electrical Wiring, Schematic Reading, National Electric Code
Raleigh, North Carolina, United States · Remote OK
$135k–$225k/yr
At RapidScale, exceptional technology is powered by exceptional people. We deliver secure, reliable managed and advisory services across private, public, and hybrid clouds, helping organizations innovate, adapt, and grow…
Skills: Program Management, Project Management, Cloud Infrastructure, Governance Frameworks, Risk Mitigation
Durham, North Carolina, United States · On-site
Job Description: Note: Fidelity will not provide immigration sponsorship for this position. The Personalization (PZN) Platform within Fidelity Brokerage is seeking a Principal Full Stack Engineer to lead the design and d…
Skills: Java, Python, AWS, Kafka, Spring Boot
Cary, North Carolina, United States · Remote OK
Senior Product Manager (Optimization and Network Analytics)- Hybrid, Cary, North Carolina or Remote in the US We’re a leader in data and AI. Through our software and services, we inspire customers around the world to tra…
Skills: Product Management, Mathematical Optimization, Operations Research, Graph Optimization, Network Analytics
Concord, North Carolina, United States · On-site
Main Duties & Responsibilities Primary Job Role Conducts all assigned work in a safe manner, adhering to all applicable safety, environmental and contamination control policies, procedures and regulations. Wears proper p…
Skills: Mechanical Troubleshooting, Electrical Troubleshooting, Hydraulic Troubleshooting, Equipment Maintenance, Component Assembly
Wilson, North Carolina, United States · On-site
$35/hr–$40/hr
Job DetailsJob Location: 011000 - Wilson, NC 27893Position Type: Full TimeSalary Range: $35.00 - $40.00 HourlyJob title: Facilities Mechanical Technician Schedule: 1st shift, 40 hours per week, (alternating weekends, 40 …
Skills: Preventive Maintenance, HVAC, Boiler Maintenance, Compressed Air Systems, Fire Suppression Systems
Winston-Salem, North Carolina, United States · On-site
Managing modern technology has become increasingly complex. As organizations scale across clouds, endpoints, and hybrid environments, IT operations and cybersecurity often remain fragmented, creating gaps in visibility, …
Skills: Technical Support, Network Troubleshooting, Active Directory, Microsoft 365 Administration, Azure Administration
Cary, North Carolina, United States • Hybrid
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Develop and manage the data historian and related systems within a GMP regulated environment, focusing on OSI PI and MQTT sources. Create operational dashboards and ensure high availability, cybersecurity compliance, and validation documentation for manufacturing systems.
Requires a Bachelor's degree in Engineering or Computer Science with 5 to 8+ years of experience in data and analytics solutions. Expertise in AVEVA PI System, MQTT, and biopharmaceutical manufacturing standards like GxP and 21 CFR Part 11 is highly preferred.
Welcome to Holly Springs, North Carolina— home to Roche/Genentech's largest-ever investment: a $2B greenfield start-up where next-generation technology, high-performing teams and Operational Excellence converge to create the global standard for high-volume, highly-efficient Drug Product manufacturing.
The facility's core is defined by Innovation - leveraging advanced automation, robotics, digital tools, real-time data analytics, and simple, streamlined processes to produce the highest quality medicines. This plant meets today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes. This is a fast-paced, entrepreneurial environment with a high-level of accountability, with planned launch in 2028.
Behind every product sold by Roche is Pharma Global Technical Operations (PT). Starting with Phase I of the development process and continuing through to product maturity, PT makes lifesaving medicines at 11 locations, with the support of partners from around the world. Information (IT) and Automation Technology (OT) teams are key in producing and delivering medicine to patients. The organization is currently undergoing a transformation towards digitalization, advancing fundamental elements to meet future needs, such as using new technologies.
As a Data & Analytics Engineer/Senior Data & Analytics Engineer, you will perform a mix of remote and onsite work (first at the General Planner’s office, later at construction site/plant). You will transition to local full-time on-site work once the site buildings are built and equipment delivered.
Development and lifecycle management of the data historian and related data systems in a GMP regulated environment.
Design, configure, and maintain the OSI PI System infrastructure including PI Data Archive, PI Asset Framework (AF), PI Vision, and PI Analysis Service.
Design and support robust data pipelines, ensuring contextualized data from OSI PI and MQTT sources is available for advanced analytics, predictive modeling, and integration with Level 4 business systems (e.g., ERP, LIMS, PLM).
Performing application administration (user admin, patching, upgrades, audit support, system and database log review and maintenance).
Software development in various languages, testing and configuration of COTS or custom applications to support HSP manufacturing systems and support of stakeholders.
Development and management of standardized Asset Framework (AF) templates, attributes, and hierarchies to represent site equipment and processes consistently.
Creation and maintenance of operational dashboards and displays in PI Vision to provide real-time visibility for manufacturing, quality, and engineering teams.
Partnering with IT and Automation teams to ensure high availability, disaster recovery, and cybersecurity compliance of the PI system.
Drafting and execution of validation documentation (IQ/OQ/PQ) and standard operating procedures (SOPs) for the PI system in accordance with 21 CFR Part 11 and GxP standards.
Performing routine system maintenance, including upgrades, security patching, and health monitoring to ensure 24/7 reliability.
Providing technical mentorship and support to system users, helping them leverage PI data for process optimization and troubleshooting.
Monitoring and analysis of manufacturing data as necessary to provide support for process discrepancies, investigations, validation protocols, process transfers, or equipment troubleshooting.
Working to identify opportunities to create additional value and improve business processes and patient outcomes, maximize the benefits of standardization of technologies and leverage across sites.
Executing implementation and delivery of projects on-site IT OT Product Portfolio.
Assisting in the development of end-user and maintenance training materials.
Providing diagnostic troubleshooting assistance to maintenance and technicians as required, including off-hour and on-call support.
Bachelor's degree in Chemical, Electrical, or Computer Engineering, Computer Science, or a related technical discipline.
5+ years of experience implementing and managing data and/or analytics solutions. Highly desirable AVEVA PI Data Historian experience or experience from other platforms that will accelerate learning on those platforms.
Prior experience in working closely with IT OT providers/vendors.
Travel of up to 30% of the time is expected during the project phase.
The expected salary range for this position based on the primary location of Holly Springs, North Carolina is $78,900- $146,500.
Bachelor's degree in Chemical, Electrical, or Computer Engineering, Computer Science, or a related technical discipline.
8+ years of experience implementing and managing data and/or analytics solutions. Highly desirable AVEVA PI Data Historian experience or experience from other platforms that will accelerate learning on those platforms.
Prior experience in working closely with IT OT providers/vendors.
Travel of up to 30% of the time is expected during the project phase.
The expected salary range for this position based on the primary location of Holly Springs, North Carolina is $95,200 - $176,800.
Ability to work in a manufacturing environment, which may include cleanrooms and technical areas.
Position requires standard office work including prolonged sitting and computer usage.
May require occasional lifting of up to 25 lbs. related to hardware maintenance.
The ideal candidate will have expertise domain knowledge in the following area(s). These skills are highly preferred.
Biopharmaceutical or similar Manufacturing domain.
Advanced knowledge of data management solutions such as AVEVA PI System.
Advanced knowledge of data management integration technologies such as OPC standards, PI connectors, PI interfaces, MQTT, RDBMS, XML, JSON, REST API, Highbyte, etc.
Proficiency with MQTT protocol and broker technologies (e.g., HiveMQ, Mosquitto).
Familiarity with modern data engineering tools and languages (e.g., Python, scripting) to manipulate and route data streams.
Knowledge of operational analytics tools such as PI Vision, SEEQ is a plus.
Knowledge of Manufacturing Execution Systems (Pharmasuite or Syncade), Manufacturing Control Systems (Emerson or Rockwell), LIMS, and SAP considered a plus.
Advanced knowledge of Good Manufacturing Practices (GMP), Health Authority practices, 21 CFR Part 11, cGMP Annex 11, Data Integrity principles.
Exhibits intellectual curiosity and integrity and has a strong passion to bring value-adding technology to the business.
Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
About Genentech We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours. If you’d like to join our team, view our openings at gene.com/careers. Our patient resource center is dedicated to getting patients and caregivers to the right resources. You can reach them at 1 (877) GENENTECH (436-3683) Monday-Friday, 6am-5pm PST or [email protected]. Community Guidelines: 1. We want to foster positive conversation around the issues we are passionate about. To that end, we remove profanity, content that contains threatening language, content that is aimed at private individuals, personal information, and repeated unwanted messages. 2. Don’t mention any medicines by name — ours or anyone else’s. Because of the fair balance rules governing our industry, we cannot post any comments that reference any pharmaceutical brand, product, or service. Please do not mention any specific medicines by name, or include any links to third party sites in your comments. 3. This isn’t the place to report or discuss side effects. This site is not intended as a forum for reporting side effects experienced while taking a Genentech product. Instead, you should report any side effects to Genentech Drug Safety at 1-888-835-2555. You can also report side effects of any prescription product directly to the FDA at 1-800-FDA-1088 or by visiting www.FDA.gov/medwatch. 4. Don’t pitch your product or service. Please don't use our page as a place to promote your product or pitch your services. Please also avoid posting links to external sites. We reserve the right to remove any posts that are deemed promotional.
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Based on 2374 listings with disclosed salaries, most engineering jobs in North Carolina pay between $75k–$180k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 7,926 open engineering positions in North Carolina listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Corning Incorporated, Eaton, North Carolina Department of Environmental Quality, Bright Vision Technologies, ABB, among others. Browse the listings above to see every active employer.
Yes — 1711 of the 7926 open engineering positions offer remote or hybrid work (496 remote, 1215 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
