Cambridge, US; Gaithersburg, US; London, United Kingdom; Mainz, Germany; New Jersey, US | full time | Job ID: 11307 About the Role At BioNTech, we are united by a shared mission to harness the power of science and innova…
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Lead the design and strategic oversight of clinical trials, including protocol development and regulatory submissions. Collaborate with cross-functional teams to execute clinical development programs and mentor junior clinical science staff.
Requirements
Requires an advanced degree in life sciences or healthcare and over 10 years of industry experience in clinical development. Must have strong expertise in GCP, Phase 1-3 drug development, and a proven track record of leading global clinical studies.
Full job description
Cambridge, US; Gaithersburg, US; London, United Kingdom; Mainz, Germany; New Jersey, US | full time | Job ID: 11307
About the Role
At BioNTech, we are united by a shared mission to harness the power of science and innovation to transform lives. As Director, Clinical Science (m/f/d), you will lead and shape clinical development strategies, playing a critical role in advancing our investigational drugs from concept to reality. You will collaborate across diverse teams to ensure the successful design and execution of clinical trials, directly contributing to our goal of improving patient outcomes worldwide. This is your opportunity to lead with impact and be part of a transformative journey in healthcare.
Your Contribution
Lead the design of clinical trials by developing study protocols, identifying patient populations, selecting endpoints, and determining optimal study designs to evaluate investigational drugs
Provide strategic oversight for clinical trial execution, ensuring adherence to protocols, regulatory requirements, and ethical standards; monitor study progress, review data, and manage adverse event
Drive the creation of key study-level documents such as protocols, Investigator’s Brochures, regulatory submissions, safety updates, and publications
Address regulatory/health authority inquiries while ensuring compliance with guidelines; contribute to preparation for regulatory meetings
Develop and oversee the Clinical Development Plan and Integrated Evidence Plan while contributing to Target Product Profiles (TPPs)
Collaborate with cross-functional teams (e.g., clinical operations, biostatistics, medical safety) to ensure seamless execution of clinical development programs
Provide leadership in developing protocol-relevant training materials for internal teams, investigator sites, CRO partners, and other stakeholders
Partner with pharmacovigilance teams on safety evaluations and signal detection; contribute to aggregate reports and patient narrative reviews
Guide data review strategies to ensure integrity across studies; support Case Report Form (CRF) development and implementation of innovative data capture tools
Mentor junior team members within the clinical science organization while fostering a culture of continuous improvement
A Good Match
Advanced degree in life sciences/healthcare/nursing (e.g., PhD or PharmD preferred)
10+ years of industry experience in clinical development or related fields with demonstrated leadership capabilities
Strong expertise in Good Clinical Practice (GCP), drug development processes (Phase 1–3), ideally paired with Oncology/Immuno-Oncology experience
Proven track record in leading global clinical studies within pharmaceutical companies or contract research organizations (CROs)
Deep understanding of clinical data collection systems (e.g., EDC systems) with experience driving process improvements for data analysis and reporting
Exceptional ability to lead cross-functional matrixed teams with strong influence skills
High adaptability with exceptional multitasking abilities under time pressure while maintaining quality standards
Strategic mindset combined with excellent prioritization skills for task implementation
Join us at BioNTech as we pioneer new frontiers in medicine. Lead with purpose and make an impact that matters!
Your benefits and remuneration:
If the position is filled in the US, the Expected Pay Range is $168,100/year to $268,700/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.
Compensation at other locations may vary significantly.
BioNTech is committed to the wellbeing of our team members and offers a variety of benefits in support of our diverse employee base. We offer competitive remuneration packages which is determined by the specific role, location of employment and also the selected candidate’s qualifications and experience.
Note: The availability, eligibility and design of the listed benefits may vary depending on the location. The final requirements for the individual use of our benefits are based on the company's internal policies and applicable law.
How to apply:
Apply now by sending us your application documents including Curriculum Vitae, copy of ID, copies of degree certificates and professional certificates, motivation letter as well as your contact details via our online form.
Please note:
Only applications sent via our online form shall be considered. By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.
We are looking forward receiving your application.
Our vision is to harness the power of the immune system to develop novel therapies against cancer & infectious diseases.
Industry
Biotechnology Research
Company size
1,001-5,000 employees
Founded
2008
Headquarters
Mainz, Rhineland-Palatinate
LinkedIn followers
300,005
Total funding
$2.0B
Biopharmaceutical New Technologies (BioNTech) is a global biotechnology company aspiring to translate science into survival by developing new immunotherapies utilizing the full potential of the immune system to fight cancer and infectious diseases.
BioNTech is headquartered in Mainz, Germany, and operates globally with almost 7.000 pioneers. Our work is powered by one mission: Improving the health of people worldwide. We believe that scientific rigor and passion are the driving forces that are essential for innovative progress.
BioNTech was founded in 2008 by scientists and physicians to translate science into survival by combining fundamental research and operational excellence. At BioNTech, we have been conducting fundamental research of mRNA technologies in the field of individualized cancer medicine for more than a decade. Some of our colleagues, including our co-founders, have been researching and developing mRNA-based vaccines for more than 25 years.
Ready to join us on this journey? Explore the opportunities and become part of a team that aspires to turn bold ideas into real-world solutions: https://www.biontech.com/int/en/home/careers.html
🔗 Privacy Statement: https://www.biontech.com/int/en/home/data-privacy-statement.html
🔗 Imprint: https://www.biontech.com/int/en/home/imprint.html
Offices: An der Goldgrube 12, Mainz, Rhineland-Palatinate 55131, DE · Vollmersbachstraße 66, Idar-Oberstein, Rhineland-Palatinate 55743, DE · Vollmerstr. 5, Berlin, Berlin 12489, DE · Am Klopferspitz 19a, Planegg, Bavaria 82152, DE · Forstenrieder Str. 8-14, Neuried, Bavaria 82061, DE
BiotechnologyIndividualized cancer medicinePatient-specific immunotherapymRNA therapeuticsCell therapyAntibody therapeuticsSmall molecule immunomodulatorsTailored therapeuticsImmunotherapyOncology
How much do Science & Research jobs in Massachusetts pay?
Based on 4280 listings with disclosed salaries, most science & research jobs in Massachusetts pay between $90k–$237k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in Massachusetts right now?
There are currently 6,922 open science & research positions in Massachusetts listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Massachusetts?
Companies currently hiring include Mass General Brigham, Harvard Division of Medical Sciences, Takeda, Sanofi, Thermo Fisher Scientific, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Massachusetts?
Yes — 2166 of the 6922 open science & research positions offer remote or hybrid work (476 remote, 1690 hybrid).
How do I apply for Science & Research jobs in Massachusetts?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.