Daly City, California, United States · On-site
$86k–$159k/yr
The Position The Opportunity We are seeking a highly motivated and collaborative Scientist 2, Neuroscience Discovery & iPSC Assay Development to advance discovery research and drug development efforts within our Neurosci…
Skills: iPSC maintenance, Cell differentiation, CNS cell models, Molecular biology, Biochemistry
San Luis Obispo, California, United States · On-site
$59k–$80k/yr
Job Summary Under the general supervision of the Plant Sciences department head, this individual primarily oversees the department’s sustainable row crop production, including vegetable and forage crops, and their associ…
Skills: Crop production, Pest management, Irrigation management, Fertilization program, Farm equipment maintenance
Pomona, California, United States · On-site
$90k–$94k/yr
Tenure Track Faculty Position Assistant Professor of Mathematics in Applied Mathematics Department of Mathematics and Statistics College of Science Salary Range: $89,720 - $93,720 California State Polytechnic University,…
Skills: Applied mathematics, Nonlinear optimization, Machine learning, Stochastic modeling, Teaching
South San Francisco, California, United States · Hybrid
$114k–$211k/yr
We advance science so that we all have more time with the people we love. Become a part of Genentech’s Early Clinical Development team, working to bring pioneering therapies to patients. As a Clinical Documentation Lead …
Skills: Medical writing, Clinical project management, Regulatory requirements, Clinical science, Protocol design
California, United States · Remote OK
$78k–$156k/yr
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnost…
Skills: Clinical support, Sales support, Electrophysiology, Structural heart, Interventional cardiology
Manhattan Beach, California, United States · On-site
$56k–$93k/yr
RELOCATION ASSISTANCE: No relocation assistance available CLEARANCE REQUIRED FOR START: No CLEARANCE TYPE: None TRAVEL: NoDescription At Northrop Grumman, our employees have incredible opportunities to work on revolution…
Skills: Semiconductor wafer handling, Molecular-beam epitaxy, MBE system operation, Wafer characterization, Microsoft Excel
South San Francisco, California, United States · Hybrid
$162k–$301k/yr
Why Genentech We’re passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly p…
Skills: Marketing strategy, Omnichannel marketing, Customer engagement, Content creation, Project management
Sunnyvale, California, United States · On-site
$177k–$247k/yr
Ranking AI is the central core machine learning org within Meta’s Monetization group, powering Meta’s revenue and business growth by advancing and deploying state-of-the-art Recommendation Systems AI for our Ads stack. W…
Skills: Data Science, Machine Learning, Recommendation Systems, SQL, Python
Santa Clarita, California, United States · On-site
$36k–$75k/yr
We are seeking Lab Associate- Automated Chemistry to join IQVIA Laboratories at Valencia, CA. We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to disc…
Skills: Laboratory testing, Specimen analysis, Analytical data generation, Regulatory compliance, SOP adherence
El Segundo, California, United States · On-site
$105k–$172k/yr
Autonomy Engineer (Mid Career) - Millennium Space Systems Company: Millennium Space Systems Millennium Space Systems, a part of Boeing Defense, Space and Security (BDS), is a fast, agile small satellite company focused o…
Skills: Satellite design, Fault detection, Isolation and response, FDIR, Autonomy software
Kernville, California, United States · On-site
$30/hr–$30/hr
Job DetailsJob Location: Kernville, CAPosition Type: SeasonalSalary Range: $30.00 - $30.00 HourlyJob Category: Cultural Resources ServicesThe Great Basin Institute, in cooperation with the USFS, is recruiting an Archaeol…
Skills: Archaeology, Cultural resource management, Field survey, Site recording, GPS navigation
South San Francisco, California, United States · Hybrid
$190k–$220k/yr
Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing …
Skills: Project management, Drug development, Clinical development, Cross-functional leadership, Strategic planning
San Diego, California, United States · On-site
$175k–$200k/yr
The Associate Director, Clinical Operations will be responsible for managing operational aspects of assigned clinical trials, with a focus on early-phase oncology studies. This includes oversight of contract research org…
Skills: Clinical operations, Oncology, Clinical trials, GCP, FDA regulations
San Diego, California, United States · On-site
$20/hr–$27/hr
Job TitleBiochemist I/II - Recombinant Protein Manufacturing Location(s)San Diego - BioLegend About Us Revvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians …
Skills: Recombinant protein expression, Protein purification, Bacterial cell culture, SDS-PAGE, DNA isolation
Burbank, California, United States · On-site
$110k–$120k/yr
Aerospace Product Developer Burbank California As an Aerospace Product Developer, you will be at the forefront of growth in the aerospace industry. In this on-site role, you will collaborate with versatile teams to devel…
Skills: Product development, Chemistry, Chemical engineering, Materials science, Scientific method
Sunnyvale, California, United States · On-site
$52k–$71k/yr
Who are we? Technical Safety Services (TSS) is a leading laboratory service provider with locations across the United States. Our customers include leading life sciences and healthcare companies and renowned research ins…
Skills: Equipment calibration, Maintenance, Troubleshooting, Problem-solving, Customer service
Carpinteria, California, United States · On-site
$88k–$138k/yr
Job Description The Histologist work in the R&D lab to assist in routine preventative maintenance/cleaning, coordinating preventive and corrective maintenance of histology laboratory equipment & instruments and also be r…
Skills: Histology, Microtomy, Embedding, Tissue fixation, Staining
Azusa, California, United States · On-site
Job Summary We are seeking a dedicated and detail-oriented Chemical Operator to join our team. In this role, you will be responsible for operating and monitoring chemical processes, ensuring compliance with safety and qu…
Skills: Chemical processing, Laboratory practices, Materials handling, Lean manufacturing, CGMP compliance
San Diego, California, United States · On-site
$102k–$154k/yr
Introduction to the Job Takes the lead in development of more complex parts of modules AND/OR drives and owns a technically complex solution. Leads several technically complex (mono-disciplinary) designs OR a functional …
Skills: Mechanical design, Technical leadership, Project management, Product development, Feasibility studies
San Bernardino, California, United States · On-site
$6k–$15k/mo
California State University, San Bernardino (CSUSB) is located in San Bernardino in the Inland Empire, 60 miles east of Los Angeles and operates a satellite campus in Palm Desert located in Coachella Valley. CSUSB serves…
Skills: Digital humanities, Immersive media, Virtual reality, Augmented reality, Mixed reality
Daly City, California, United States • On-site
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The scientist will generate and differentiate human iPSCs into CNS cell models to execute functional assays and support disease-relevant phenotyping. They will also manage lab operations, document experimental data, and present findings to multidisciplinary project teams.
Candidates must hold a Bachelor's degree with 6+ years of experience or a Master's degree with 4+ years of experience in iPSC and mammalian cell culture. Proficiency in molecular biology, cell-based assay execution, and independent experimental design is required.
The Opportunity
We are seeking a highly motivated and collaborative Scientist 2, Neuroscience Discovery & iPSC Assay Development to advance discovery research and drug development efforts within our Neuroscience team. In this role, you will leverage human induced pluripotent stem cells (iPSCs) to generate relevant central nervous system (CNS) cell models, execute functional assays, and support disease-relevant phenotyping. You will thrive in a fast-paced, matrix environment, bringing strong scientific rigor, a proactive problem-solving mindset, and a commitment to data quality and reproducibility.
Key Responsibilities:
Perform culture, banking, and quality control of human iPSCs, and differentiate iPSCs into CNS cell lineages (neurons, glia) following established protocols.
Manage and maintain routine primary neuronal cultures to support comparative and complementary functional studies.
Design, optimize, and execute robust cell-based assays supporting neuroscience pipeline programs, implementing new technology platforms when needed.
Support genetic and pharmacological proof-of-concept studies through precise execution of experimental workflows.
Generate, analyze, and document complex experimental data with a focus on high reproducibility, maintaining accurate Electronic Lab Notebook (ELN) records.
Present scientific findings and actionable insights to multidisciplinary project teams via reports, presentations, and team discussions.
Oversee iPSC lab operations, ensuring efficient shared reagent management, equipment maintenance, and adherence to safety protocols.
Who You Are
You are a curious, detail-oriented researcher who thrives in a collaborative scientific environment and is passionate about leveraging advanced cell models to transform neuroscience discovery.
Qualifications & Experience:
Bachelor’s degree in Cell Biology, Molecular Biology, Neuroscience, or a related field with 6+ years of laboratory experience, OR a Master’s degree with 4+ years of experience in iPSC and mammalian cell culture (industry or academia).
Demonstrated technical proficiency in human iPSC maintenance, banking, quality control, and directed differentiation into CNS cell types (neurons, microglia, astrocytes, or oligodendrocytes).
Hands-on expertise in molecular biology, advanced optical imaging, biochemistry, molecular profiling, and executing plate-based or high-content imaging assays.
Strong skills in independent experimental design, organization, critical thinking, and written/verbal communication.
Preferred: Familiarity or hands-on experience with CRISPR/Cas9 gene editing, arrayed/pooled CRISPR screens, or single-cell RNA sequencing (scRNA-seq) workflows.
Preferred Qualifications
Hands-on experience with CRISPR/Cas9 editing in iPSCs (guide design, RNP/lentiviral/transfection delivery, clone isolation, and genomic validation).
Experience with arrayed or pooled CRISPR screens (library preparation, transduction, NGS sample prep).
Familiarity with single-cell RNA sequencing (scRNA-seq) workflows and data interpretation using R and/or Python.
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of South San Francisco, CA is $85,500 to $158,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
About Genentech We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours. If you’d like to join our team, view our openings at gene.com/careers. Our patient resource center is dedicated to getting patients and caregivers to the right resources. You can reach them at 1 (877) GENENTECH (436-3683) Monday-Friday, 6am-5pm PST or [email protected]. Community Guidelines: 1. We want to foster positive conversation around the issues we are passionate about. To that end, we remove profanity, content that contains threatening language, content that is aimed at private individuals, personal information, and repeated unwanted messages. 2. Don’t mention any medicines by name — ours or anyone else’s. Because of the fair balance rules governing our industry, we cannot post any comments that reference any pharmaceutical brand, product, or service. Please do not mention any specific medicines by name, or include any links to third party sites in your comments. 3. This isn’t the place to report or discuss side effects. This site is not intended as a forum for reporting side effects experienced while taking a Genentech product. Instead, you should report any side effects to Genentech Drug Safety at 1-888-835-2555. You can also report side effects of any prescription product directly to the FDA at 1-800-FDA-1088 or by visiting www.FDA.gov/medwatch. 4. Don’t pitch your product or service. Please don't use our page as a place to promote your product or pitch your services. Please also avoid posting links to external sites. We reserve the right to remove any posts that are deemed promotional.
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