Cambridge, Massachusetts, United States · Hybrid
$255k–$345k/yr
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer, with the flexibility and confidence to work in therapeutic areas that may be beyond their particular expertise or experience. This is a…
Skills: Clinical Development Strategy, Clinical Trial Design, Regulatory Submissions, Drug Development, Biostatistics
Cambridge, Massachusetts, United States · Hybrid
$230k–$316k/yr
About This Role The Sr Director, Insights and Analytics Lead, will support the Neuropsychiatry/Women’s Health franchise by objectively defining and evaluating brand performance, enabling data-driven decisions, and proact…
Skills: Market Research, Forecasting, Competitive Intelligence, Brand Analytics, Field Analytics
Cambridge, Massachusetts, United States · Hybrid
$161k–$201k/yr
Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs …
Skills: Commercial Analytics, Business Operations, Tableau Development, Veeva CRM, Data Reporting
Cambridge, Massachusetts, United States · On-site
$94k–$137k/yr
Site: The Spaulding Rehabilitation Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance…
Skills: Clinical Nursing Care, Curriculum Development, Clinical Assessment, Critical Thinking, Evidence-Based Practice
Cambridge, Massachusetts, United States · Hybrid
$177k–$278k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: AI/ML, Drug Discovery, Technical Due Diligence, Strategic Scouting, Partnership Evaluation
Gaithersburg, Maryland, United States · On-site
$146k–$234k/yr
Associate Director, Projects & Strategy, Analytics, Science & Technology (AS&T) Gaithersburg, US | full time | Unlimited | Job ID: 11533 About the Role: As Associate Director, AS&T Projects & Strategy, you will play a ke…
Skills: Analytical Development Strategy, CMC Module 3 Dossier, Stakeholder Management, Regulatory Compliance, Project Management
Cambridge, Massachusetts, United States · On-site
$154k–$243k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Consumer Marketing Strategy, Tactic Planning, TV/CTV Advertising, Digital Marketing, Agency Management
Cambridge, Massachusetts, United States · Hybrid
$179k–$298k/yr
Job title: Data Management Lead Location: Cambridge, MA / Morristown, NJ *Hybrid - 3 days per week onsite is required. * About the job Join the digital engine driving Sanofi’s transformation - where AI, automation, and b…
Skills: Strategic Thinking, Data Product Management, Therapeutic Area Data Expertise, Governance & Compliance, Data Stewardship
Cambridge, Massachusetts, United States · Remote OK
$131k–$209k/yr
The Role: Moderna Services, Inc. seeks a Sr. Manager, Clinical Data Management for its Cambridge, Massachusetts location. Here’s What You’ll Do: Lead data management activities for in-house and outsourced studies. Respon…
Skills: Vendor Management, Clinical Data Management, Medidata RAVE, InForm, Oracle Clinical
Cambridge, Massachusetts, United States · On-site
$116k–$131k/yr
The Opportunity Lesley University is seeking a Director of Labor Relations to join the Human Resources department. Reporting to the Associate Vice President of HR, the Director will lead the University’s labor relations …
Skills: Collective Bargaining, Labor Relations, Contract Interpretation, Grievance Management, Arbitration
Cambridge, Massachusetts, United States · On-site
$179k–$258k/yr
Job title: Global Director, Diagnostics and Scientific Affairs Location: Cambridge, MA About the job Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive br…
Skills: Diagnostic Strategy, Precision Medicine, Biomarker Development, Molecular Diagnostics, Genomics
Cambridge, Massachusetts, United States · On-site
$252k–$377k/yr
Are you a visionary expert in clinical drug development, possessing the capabilities to drive a successful strategy in accelerating the development of cellular therapies for patients with immune-mediated diseases? Are yo…
Skills: Clinical Drug Development, Asset Strategy, Life Cycle Management, Target Product Profile, Cross-functional Leadership
Gaithersburg, Maryland, United States · On-site
$146k–$234k/yr
Associate Director, Projects & Strategy, Analytical Sciences & Technology (AS&T) Gaithersburg, US | full time | Unlimited | Job ID: 11533 About the Role: As Associate Director, AS&T Projects & Strategy, you will play a k…
Skills: Analytical Development, Project Management, Stakeholder Management, CMC Strategy, Regulatory Compliance
Cambridge, Massachusetts, United States · Hybrid
$146k–$234k/yr
The Role: Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of infrastructure (cloud and on-prem) rationalization and AI-readiness initiatives at Moderna globally. We’re …
Skills: Program Management, Infrastructure Engineering, Cloud Modernization, ITSM, Stakeholder Management
Cambridge, Massachusetts, United States · Remote OK
$122k–$204k/yr
Job Description SummaryAs an Executive Recruiter at GE Vernova, you will own the strategy & execution of executive level searches that directly shape how GEV delivers the energy transition. You will advise senior executi…
Skills: Executive Search, Talent Acquisition, Executive Compensation, Talent Analytics, Market Mapping
Cambridge, Massachusetts, United States · Hybrid
$120k–$145k/yr
About Manifold Manifold is the AI platform for life sciences, accelerating life-changing medicines to patients. Our products speed up workflows in areas from target identification and clinical development to market acces…
Skills: Customer Success, Implementation Management, Professional Services, Project Management, AI Workflow Integration
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Operational Analysis, Data Modeling, Project Management, Change Management, Process Improvement
Cambridge, Massachusetts, United States · On-site
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Custodial Supervision, Cleaning Procedures, Performance Management, Staff Training, Budgeting And Finance
Cambridge, Massachusetts, United States · On-site
$66k–$80k/yr
JOB SUMMARY Assists in managing the execution of all operations in the rooms area departments (e.g.,Front Office, Engineering/Maintenance, Housekeeping) and managing staff. Strives to continually improve guest and employ…
Skills: Rooms Operations Management, Guest Services, Staff Leadership, Financial Performance Monitoring, Customer Service
Cambridge, Massachusetts, United States · Hybrid
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enric…
Skills: Clinical Development, Medical Monitoring, Oncology, Translational Medicine, Regulatory Submissions
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The Director will provide strategic clinical leadership for RNAi therapeutics, specifically focusing on ATTR amyloidosis programs. They will oversee trial conduct, safety, and regulatory submissions while collaborating across a matrix organization to integrate development strategies.
Requires an MD or MD PhD with board certification or specialist training in cardiology and at least 3 years of industry or clinical academic experience. Candidates must possess strong scientific judgment and a proven track record of leading clinical research in a biotech or pharma environment.
Overview
Alnylam Pharmaceuticals is seeking an imaginative physician drug developer, with the flexibility and confidence to work in therapeutic areas that may be beyond their particular expertise or experience. This is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam’s rapidly expanding portfolio, which spans from rare genetic to common diseases.
The successful candidate’s primary role will be as one of the clinical leads in a clinical development program in ATTR amyloidosis. He/she will report directly into the program medical lead who provides the clinical research oversight of the program. He/she is expected to play a leading and influencing role in the overall clinical development strategies for the molecules and drive progress and operational excellence for associated clinical trials. In addition, this role will include interaction with Alnylam’s research group, helping to advise the team on the clinical development feasibility of novel targets and the design of proof-of-concept studies. This work will also involve extensive consultation and collaboration with external experts. It is anticipated that additional opportunities will arise to lead bench-to-bedside early phase clinical development programs. The Director, Clinical Research, will work in a matrix organization across Regulatory, Biostatistics, Clinical Operations, Preclinical, Commercial & Quality Assurance teams to ensure fully harmonized and integrated development strategies. He/she will be a key Alnylam Development spokesperson at external meetings, including regulatory interactions and scientific meetings.
*This a hybrid position with 2 days a week onsite presence in our Cambridge, MA or Philadelphia, PA office required.
• Be the strategic leader providing a strong, clear voice for the clinical program.
• Develop creative but realistic approaches to drug development and lead clinical efforts to secure global regulatory approvals.
• Oversight of trial conduct and safety
• Provide strategic consultation and guidance to Research on all decisions that have significant clinical components and implications.
• Collaborate closely with Preclinical, Regulatory Affairs and Medical Affairs to ensure tight strategic integration of product development plans.
• Be accountable via Clinical Research and Operations for all relevant timelines and deliverables.
• Supervise closely all major written deliverables (regulatory submissions, original articles, abstracts), and presentation materials.
• Be responsible for final review and sign off with respect to all controlled documents including protocols, investigator brochures, and informed consent forms.
• Influence internal and external audiences in a high impact, highly visible fashion
A highly driven, dynamic, engaged and accomplished physician-scientist with experience and insight will thrive in this role. Specific qualifications include:
MD with strong research background or MD PhD with best of class clinical and/or research training as shown through research support and peer-reviewed publications.
Board Certification (or equivalent) or specialist training in cardiology
Expertise in heart failure and/or amyloidosis is desirable
3+ years industry experience or equivalent clinical academic experience
Sound scientific and clinical judgment
Familiarity with concepts of clinical research and clinical trial design, including biostatistics, and regulatory agency organization, guidelines, and practices
Ability to effectively present ideas and document complex medical/clinical concepts in both written and oral communication
History of solving problems while exhibiting superior judgment and a balanced, realistic understanding of issues
Outstanding leadership and collaboration skills working within a matrix environment
Experience and knowledge of working with biotech/pharma partner(s)
Thrives in highly entrepreneurial biotech environment and embraces Alnylam’s culture of science, passion and urgency.
#LI-JB1 #LI-Hybrid
$255,000.00 - $345,000.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.
Alnylam is the leading RNAi therapeutics company. We're a fast-growing biopharma with a deep pipeline and global reach.
SILENCE DISEASE. AMPLIFY LIFE.™ Alnylam is a leading independent biopharmaceutical company and the pioneer in RNA interference (RNAi) therapeutics – a revolutionary approach to treating diseases which “silences” the genes that cause or contribute to them. Founded in 2002 by a group of distinguished researchers and biotech leaders, Alnylam’s work over more than two decades has yielded the critical breakthroughs and advancements that have made the field of (RNAi) therapeutics possible. In 2018, our first commercial medicine, and the world’s first RNAi therapeutic was approved. Since then, five more Alnylam-developed medicines have been approved and we’re hard at work developing new therapies to treat both rare and prevalent diseases. We are a global and diverse company of 2,600+ people. We pride ourselves on fostering a fun, inclusive and dynamic work environment where employees can recognize their fullest potential. That's why we’re consistently ranked as a top employer by The Boston Globe (2015-24), Science Magazine (2018-25), Fast Company (Best Workplaces for Innovators 2020-25) and LinkedIn (2024). We are based in Cambridge, Massachusetts (U.S.), with offices throughout North America, Europe, Asia, and South America. See our social media community guidelines: https://bit.ly/2FcRhJy. Please note: If you wish to report an adverse event or product complaint, please email [email protected] or you may call us using the following telephone numbers: for North America, 877.ALNYLAM (877.256.9526), for Europe, +31 20 369 7861 Fraudulent Recruitment Activity Be aware of the potential for scams and fraudulent recruitment activity from individuals claiming to represent Alnylam Pharmaceuticals. Alnylam never conducts its interview process via messaging apps, freelance sites, or social media platforms. Alnylam team members only communicate with potential candidates through an official Alnylam email address ending in "@alnylam.com."
Offices: 675 W Kendall St, Cambridge, Massachusetts 02142, US · 27 Market Street, Maidenhead, England SL6 8AA, GB · Grafenauweg 4, Zug, Zug 6300, CH · Antonio Vivaldistraat 150, Amsterdam, North Holland 1083, NL · Maximilianstraße 35a, Munich, Bavaria 80539, DE
Based on 716 listings with disclosed salaries, most management & leadership jobs in Cambridge, MA pay between $109k–$281k per year. Individual offers vary with seniority, company size, and specialization.
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