Cambridge, Massachusetts, United States · On-site
$122k–$177k/yr
Job Title: CMC Demand & Supply Leader Location: Framingham, MA About the Job Within CMC function, in the Global CMC Project Management department, the ambition is to expand a strong End to End R&D Supply Demand integrati…
Skills: Demand Management, CMC, Forecasting, Project Management, Data Analytics
Cambridge, Massachusetts, United States · Hybrid
$101k–$145k/yr
Job Title: Global Submission Manager Location: Morristown, NJ About the job The Global Submission Manager applies global expertise in managing all submission types for the GRA portfolio, from standard to complex. Represe…
Skills: Regulatory Affairs, Project Management, eCTD, Dossier Assembly, ICH Standards
Cambridge, Massachusetts, United States · On-site
Halo is a technology company building the future of haircare for all textures through exceptional engineering and human-centered design. We create category-defining products built for the complexities others overlook. We…
Skills: CAD, Mechanical Design, Robotics, Consumer Electronics, Rapid Prototyping
Cambridge, Massachusetts, United States · Hybrid
$82k–$220k/yr
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Systems Engineering, Requirements Engineering, MBSE, Digital Engineering, SysML
Cambridge, Massachusetts, United States · On-site
$73k–$188k/yr
When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives. Reporting to the Director of Quality & Patient Safety, the Quality and Patient Safety nurse specialist play…
Skills: Risk Management, Quality Assessment, Utilization Management, Data Analysis, Clinical Chart Review
Cambridge, Massachusetts, United States · Remote OK
$130k–$180k/yr
Position Overview: We are seeking a highly motivated Clinical Drug Supply Manager, Radiopharmaceuticals, to lead the planning, coordination, and execution of clinical supply activities for our radiopharmaceutical program…
Skills: Clinical Supply Chain Management, Radiopharmaceutical Handling, GMP Compliance, GDP Compliance, Vendor Management
Cambridge, Massachusetts, United States · Remote OK
Quaise Energy is unlocking Earth’s deep heat to deliver clean, reliable, baseload energy at scale – almost anywhere in the world. As both a technology innovator and project developer, Quaise builds and operates solutions…
Skills: Social Media Management, Content Development, Internal Communications, Event Planning, Storytelling
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Sql, Tableau, Power Bi, Quantitative Analysis, Statistical Modeling
Cambridge, Massachusetts, United States · On-site
$125k–$237k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: Clinical Study Operations Management, Stakeholder Management, Clinical Operational Strategies, Budget Oversight, Vendor Management
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Facilitation, Group Leadership, Relationship Building, Interpersonal Communication, Strategic Thinking
Cambridge, Massachusetts, United States · On-site
$65k–$80k/yr
About Cartesian Cartesian is building spatial intelligence for indoor environments to drive operational efficiency. We’re tackling one of the biggest challenges in the $35T global retail industry: in-store inventory visi…
Skills: Operational Workflows, Finance Operations, Project Coordination, Event Management, Customer Success
Cambridge, Massachusetts, United States · Hybrid
$223k–$265k/yr
Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitmen…
Skills: National Payer Strategy, PBM Relationship Management, Rare Disease Reimbursement, Coverage Policy Development, Utilization Management
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Strategic Leadership, Budget Management, Technical Services Management, Metadata Management, Staff Development
Cambridge, Massachusetts, United States · On-site
$185k–$225k/yr
Company Overview: Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with …
Skills: Quality Systems Management, Compliance Oversight, Treatment Center Onboarding, GxP Compliance, Auditing
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Strategic Leadership, Budget Management, Technical Services Operations, Metadata Management, Staff Development
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Strategic Leadership, Budget Management, Technical Services Operations, Metadata Management, Staff Development
Cambridge, Massachusetts, United States · On-site
$350k–$460k/yr
Company Description Metaphore Biotechnologies is a Flagship Pioneering-founded company focused on creating a new class of functional biological therapeutics. We are pioneering the power of function-first AI drug design a…
Skills: Generative Models, Protein Design, Deep Learning, ML-ops, Transformers
Cambridge, Massachusetts, United States · On-site
$22/hr–$25/hr
Assistant Store Manager Position Summary: We are seeking a dynamic Assistant Store Manager to help lead our retail team in delivering exceptional customer experiences while supporting daily operations and achieving busin…
Skills: Leadership, Team Development, Customer Service, Sales Performance, Inventory Control
Cambridge, Massachusetts, United States · Hybrid
$94k–$127k/yr
Corporate Paralegal, Legal Department Overview Alnylam, a leading biotechnology company, is looking for a Paralegal to join its Legal Department. This role is reporting to the SVP, General Counsel, Governance and Corpora…
Skills: Legal Research, Corporate Governance, SEC Filings, Contract Management, Minute Book Maintenance
Cambridge, Massachusetts, United States · Hybrid
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enric…
Skills: Clinical Program Management, Project Planning, Cross-functional Leadership, Vendor Management, Budget Management
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
Lead the integration of project strategy, clinical, and CMC operational plans to optimize end-to-end demand and supply. Responsible for forecasting clinical demand, managing sourcing strategies for marketed products, and ensuring timely delivery of drug products to packaging sites.
Requires a degree in Sciences, Pharmacy, or Engineering with 3-8 years of R&D or Clinical Development experience depending on the degree level. Must have at least 2 years of demand management experience in specific therapeutic areas and knowledge of GMP/GCP regulations.
Job Title: CMC Demand & Supply Leader
Location: Framingham, MA
About the Job
Within CMC function, in the Global CMC Project Management department, the ambition is to expand a strong End to End R&D Supply Demand integrating Demand Forecast & Planning of Supplies, supporting Projects Development and Operations through the entire value chain (from R&D to LCM). With the aim of developing a Demand & Supply Center of Excellence, the mission of the Demand & Supply Leader is to integrate Project Strategy, Clinical and CMC Operational plans for an early definition and optimization of E2E Demand & Supply plan while considering cost & risk to support execution of Projects in respect to Regulatory and Quality requirements.
This role offers the opportunity to join a dynamic and skilled team at a pivotal time as we strengthen our in-house expertise, accelerate digital transformation initiatives, and build sustainable internal capabilities to support an increasing portfolio of innovative projects across multiple therapeutic areas.
Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Lead collaborative work with Global project Management, Clinical Development and CMC to define clinical assumptions and CMC hypothesis to forecast Clinical Demand.
Forecast Long Range Plan Demand based on assumptions worked with interfaces.
Consolidate non-clinical & clinical demand and propagate to M&S Global Supply Chain.
Integrate all Development Demand and align with operational plans (CMC, CSO, TMED, DMPK, PCS) and Regulator submission/approval plans.
Run forecast & alignment scenario with associated risks and costs to support strategic project decisions and budget definition.
Co-lead Demand & Supply Sub Team and ensure End to End supply optimization with the contribution of key stakeholders.
Accountable for defining the best sourcing and supply strategy for marketed products/comparators, including forecast and budget.
Lead the definition of drug products blinding strategy to ensure clinical trial products indistinguishability.
Ensure DS/DP batches allocation to IMP batches and on time products delivery to packaging sites and oversee associated Material Flow & Documentation management.
Provide reporting/KPIs to monitor & improve Supply performance
Contribute to project documents & meetings preparation by providing standard Demand & Supply Reports (e.g. IDCC/DWG/ORC, IDP, Operational plan, Supply agreement).
Can support transversal initiatives contributing to simplification & harmonization.
About You
Basic Qualifications
Education
PhD in Sciences (Neurosciences, Microbiology, Immuno-inflammation, Gene Therapy, Rare Diseases, Pharmaceutical Sciences, Biochemistry, Molecular Biology, Biotechnology, Biomedical Sciences, Genetics), Pharmacist, or Engineer in Health Sciences, Chemical Engineering, or Biomedical Engineering
OR Master of Science (MS) degree in any of the above fields
OR Bachelor of Science (BS) degree in any of the above fields
Related scientific or life sciences disciplines will be considered
Experience
PhD holders: Minimum 3 years in Research and Development or Clinical Development.
Master's holders: Minimum 5 years in Research and Development or Clinical Development.
Bachelor's holders: Minimum 8 years in Research and Development or Clinical Development.
Minimum 2 years in Demand Management in Research and Development in the domain of Oncology, Immuno-inflammation, Rare Disease, Neurology, or Multiple Sclerosis (included within total years of experience, not additional)
CMC experience.
Ability to navigate complex and regulated environments (GMP and GCP regulations)
Knowledge of data analytics and forecasting
Project Management experience
Preferred Qualifications
Experience in the development of diverse modalities (Mammalian, Genomic, Microbial, Synthetics)
Excellent knowledge of Projects Development, Clinical & Preclinical Development, Clinical Supply Chain, CMC, R&D and M&S interfaces
PMI certification
Experience in Power BI/Power App and project management software
Experience in management of co-development projects, companies' integration and contracts management
Knowledge of Industrial Supply Chain principles
Strong interpersonal/networking skills, team-work and transversal collaboration
Ability to understand complex processes quickly and act as referent for the department
Strong ability to work under pressure and address complex situations
Team management experience is a plus
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
Help improve the lives of millions of people globally by making drug development quicker and more effective.
Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
#GD-SA
#LI-SA
#LI-Onsite
#vhd
Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.
At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.
Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!
US and Puerto Rico Residents Only
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
North America Applicants Only
The salary range for this position is:
$122.250,00 - $176.583,33All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.
We are an R&D driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time. Interactions with this account must comply with the Terms: https://bit.ly/sanofi-terms
Offices: 46 Avenue de la Grande-Armée, Paris, France 75017, FR · Karachi, Sindh 75300, PK · 11 Beach Rd, Singapore, Singapore, SG · Francisco Garcia Cortinas 2357, Montevideo, 11300, UY · 1 Discovery Dr, Swiftwater, PA 18370, US
Based on 716 listings with disclosed salaries, most management & leadership jobs in Cambridge, MA pay between $109k–$281k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 941 open management & leadership positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Harvard Division of Medical Sciences, Sanofi, Takeda, Novartis, Biogen, among others. Browse the listings above to see every active employer.
Yes — 498 of the 941 open management & leadership positions offer remote or hybrid work (69 remote, 429 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
