London, England, United Kingdom · Hybrid
Summary We are seeking an Associate Director / Director of Clinical Imaging who will be expected to take on a highly visible role with internal and external stakeholders through development of the strategy and management…
Skills: Clinical imaging, Dosimetry, Radioligand therapy, Oncology, SPECT/CT
Tarrytown, Georgia, United States · Hybrid
$255k–$425k/yr
Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an Executive Director to join our Global Patient Safety team. The…
Skills: Pharmacovigilance, Safety systems, Data architecture, AI-enabled capabilities, GxP compliance
Cambridge, Massachusetts, United States · Hybrid
$184k–$276k/yr
Job Title: Translational Medicine Lead, Associate Director, Oncology Location: Cambridge, MA Introduction to role: Are you ready to turn cutting-edge biomarker science into confident clinical decisions that change patien…
Skills: Translational medicine, Oncology, Biomarker strategy, Clinical development, Tumor biology
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Collection development, Budget management, Resource selection, Licensing negotiation, Data analysis
Cambridge, Massachusetts, United States · Remote OK
$416k–$468k/yr
Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitmen…
Skills: Clinical Development, Team Management, Clinical Trial Design, Regulatory Engagement, Stakeholder Collaboration
Cambridge, Massachusetts, United States · Hybrid
$115k–$135k/yr
Warning: Fraudulent Job Adverts Beware of fraudulent activities claiming to represent Insurify. We are not associated with any entities soliciting personal information or payment. The safety of our job seekers is a top p…
Skills: Programmatic Monetization, Ad Operations, Supply-side Partnership Management, Performance Marketing Metrics, Account Management
Cambridge, Massachusetts, United States · Remote OK
$230k–$260k/yr
The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting company, bringing together exp…
Skills: Medical affairs strategy, Oncology, Clinical development, Advisory boards, Investigator-sponsored research
Cambridge, Massachusetts, United States · Remote OK
$216k–$252k/yr
The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting company, bringing together exp…
Skills: Oncology, Thought leader engagement, Commercial strategy, Launch readiness, Stakeholder management
Cambridge, Massachusetts, United States · Hybrid
$221k–$249k/yr
Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitmen…
Skills: Biostatistics, Clinical Trial Design, SAS, R, CDISC Standards
Cambridge, Massachusetts, United States · On-site
$28/hr–$35/hr
Hiring Range: $28.00 - $35.00 The posted salary range reflects Eastern’s expected hiring range. Actual pay may vary based on experience, skills, and market factors; additional compensation may apply. Eastern offers a rob…
Skills: Retail banking, Sales coaching, Team leadership, Customer service, Branch operations
Cambridge, Massachusetts, United States · Remote Solely
$90k/yr
About the role: The Associate Director of Product Marketing connects iCivics’ products, services, and resources with the educators and education leaders they are designed to serve. This role leads product marketing…
Skills: Product marketing, Integrated marketing campaigns, Go-to-market strategy, Campaign management, Copywriting
Cambridge, Massachusetts, United States · On-site
Η TERNA ENERGY, μέλος του Ομίλου MASDAR, αναζητά: Electrical Construction Engineer Κύριες Αρμοδιότητες: · Επιβλέπει και συντονίζει τις ηλεκτρολογικές και ηλεκτρομηχανολογικές εργασίες στα εργοτάξια των έργων. · Παρακολου…
Skills: Electrical Engineering, Construction Management, Site Supervision, Project Coordination, Subcontractor Management
Cambridge, Massachusetts, United States · On-site
$147k–$221k/yr
Overview The successful candidate will be part of a team responsible for understanding the disposition mechanisms and pharmacokinetic/pharmacodynamic (PK/PD) relationships of oligonucleotide therapeutics and other emergi…
Skills: DMPK, Pharmacokinetics, Pharmacodynamics, Oligonucleotide therapeutics, ADME
Cambridge, Massachusetts, United States · On-site
$168k–$197k/yr
Electronics Engineer, IS-0855-15 Application Deadline: 11 September 2026 Department: Smithsonian Astrophysical Observatory Employment Type: Full Time Location: Cambridge, MA Compensation: $167,560 - $197,200 / year Descr…
Skills: Electronics Engineering, Systems Engineering, RF Systems, Embedded Systems, High-speed Digital Design
Gaithersburg, Maryland, United States · On-site
$146k–$234k/yr
Gaithersburg, US | full time | Job ID: 11533 About the Role: As Associate Director, AS&T Projects & Strategy, you will play a key role in advancing our late-stage protein pipeline for Monoclonal Antibodies (mAbs) and Ant…
Skills: Analytical Development Strategy, CMC Module 3 Dossier, Stakeholder Management, Regulatory Compliance, Project Management
Gaithersburg, Maryland, United States · On-site
$146k–$234k/yr
Gaithersburg, US | full time | Job ID: 11533 About the Role: As Associate Director, AS&T Projects & Strategy, you will play a key role in advancing our late-stage protein pipeline for Monoclonal Antibodies (mAbs) and Ant…
Skills: Analytical sciences, Monoclonal antibodies, Antibody-drug conjugates, CMC, Regulatory affairs
BiogenCambridge, Massachusetts, United States · Remote OK
$158k–$242k/yr
Preference will be given to candidates who can work in a hybrid arrangement, with weekly presence onsite at our headquarters in Cambridge, MA. However, remote work may be available for highly qualified candidates residin…
Skills: Epidemiology, Observational research, Cohort studies, Database studies, Literature review
Cambridge, Massachusetts, United States · On-site
$82k–$220k/yr
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Software architecture, Embedded systems, Team leadership, Mission critical systems, Safety critical systems
Cambridge, Massachusetts, United States · Hybrid
$154k–$230k/yr
Associate Director, Human Resources Business Partner Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and streng…
Skills: Human Resources Business Partnering, Organizational Design, Workforce Planning, Talent Development, Performance Management
Cambridge, Massachusetts, United States · Hybrid
$185k–$215k/yr
KAYAK, part of Booking Holdings (NASDAQ: BKNG), is a leading travel search engine. With billions of queries across our platforms, we help people find their perfect flight, stay, rental car and vacation package. We’re als…
Skills: Media planning, Media buying, Budget management, Strategic planning, Marketing measurement
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Develop and implement clinical imaging and dosimetry strategies to support radioligand therapy clinical development programs. Oversee imaging vendors, site qualification, and regulatory documentation to ensure high-quality data collection across clinical trials.
Requires an advanced degree in medical physics, nuclear medicine, or a related field with at least 5 to 8 years of relevant industry experience. Candidates must possess direct experience in oncology radiopharmaceutical imaging, dosimetry estimation, and clinical trial protocol design.
We are seeking an Associate Director / Director of Clinical Imaging who will be expected to take on a highly visible role with internal and external stakeholders through development of the strategy and management of imaging and dosimetry for clinical protocols in ARTBIO's Radioligand Therapy (RLT) clinical development programs. As a critical member of the Clinical Team, you will work closely with program leads, functional heads and subject matter experts to advance the company's development pipeline.
\nResponsibilitiesImaging and dosimetry strategy
Develop clinical imaging and dosimetry strategies designed to support clinical development plans for ARTBIO's RLT agents.
Design and implement imaging protocols, plans and procedures for clinical studies.
Define quantitative imaging standards across the portfolio, including acquisition and reconstruction parameters, calibration and QC frameworks, and site qualification criteria for SPECT/CT and PET/CT.
Oversight of dosimetry methodology: segmentation and registration, time-activity curve fitting, time-integrated activity estimation, and organ- and lesion-level absorbed dose calculation.
Evaluate and integrate emerging imaging methods, including surrogate-isotope approaches and automated lesion segmentation.
Trial documentation and design
Author imaging charters, site imaging manuals, data transmittal specifications and analysis plans.
Contribute imaging and dosimetry content to protocols, amendments, schedules of assessment, informed consent forms, Investigator's Brochures and clinical study reports.
Site and vendor execution
Provide oversight and guidance for all aspects of Medical Imaging for clinical trials.
Oversee site imaging feasibility, qualification and activation, including equipment surveys, phantom acceptance, test transmissions, and cross-calibration between dose calibrator and camera.
Deliver training on imaging requirements and response criteria to investigators, technologists, study teams and CRAs, and at investigator meetings.
Oversee CRO vendors including imaging core labs and dosimetry vendors.
Manage the resolution of technical, radiological and dosimetry questions and issues on a study and program level.
Regulatory, scientific and external engagement
Deliver subject matter expertise regarding advanced imaging techniques (including PET/CT, SPECT/CT, MRI, CT and other modalities as needed), image evaluation, and dosimetry estimation.
Support health authority interactions on imaging and dosimetry, including IND/CTA content and responses to agency questions.
Lead imaging and dosimetry academic collaborations, contractor and vendor/partner interactions, and build and maintain a network of external experts to inform protocol design.
Provide scientific and technical support and oversight in research activities.
Contribute to abstracts, posters, manuscripts and scientific presentations.
Advanced degree (MSc, PhD or MD) in medical physics, nuclear medicine physics, biomedical engineering, radiochemistry or a closely related discipline. An equivalent clinical qualification (nuclear medicine physician, certified medical physicist or senior nuclear medicine technologist) with commensurate clinical trial experience will also be considered.
Minimum 5 years of relevant industry experience for appointment at Associate Director; 8 or more years for appointment at Director.
Direct experience designing and managing imaging aspects of clinical protocols for oncology radiopharmaceutical agents, including study design, endpoint selection, dosimetry, harmonisation between clinical sites and imaging core lab oversight.
Specific experience with imaging study design and direct or indirect estimation of normal organ and tumour dosimetry for early-stage clinical development of RLT agents.
Demonstrated expertise in quantitative SPECT/CT and PET/CT in a clinical setting.
Working knowledge of internal dosimetry principles.
Experience authoring imaging charters and site imaging manuals to regulatory standards
Experience selecting and governing imaging CROs, core laboratories or dosimetry vendors.
Fluency in oncology response assessment, including RECIST 1.1, PCWG and molecular imaging response frameworks.
Experience contributing imaging or dosimetry content to IND/CTA submissions and responses to health authority questions.
Preferred
Direct experience with 212Pb, or with other alpha emitters.
Experience with elementally matched imaging surrogates for treatment planning, including 203Pb.
Prostate cancer experience, and familiarity with PSMA PET tracers and response criteria.
First-in-human and dose-escalation experience.
Prior experience at an imaging CRO or imaging core laboratory.
Personal Attributes
Proactive, detail-oriented, and eager to learn.
Comfortable working in a fast-paced biotech environment; hands-on and self-directed.
Team player who thrives on collaboration and cross-functional flexibility.
Demonstrated ability to work well under pressure, both independently and as part of a team.
Strong organisational, planning, and time management skills.
Commitment to safety, continuous improvement, and staying current with industry trends and advances.
What We Offer
A unique chance to contribute to first-in-class cancer therapies.
Exposure to both imaging and clinical development in a dynamic biotech setting.
Hands-on training and professional development opportunities.
An international, collaborative, and supportive work culture.
Competitive compensation and benefits.
Channeling Energy. Changing Lives. ARTBIO redefines cancer care by discovering and developing a new class of Alpha Radioligand Therapies (ARTs), powered by unique Pb-212 isotope technology and seamless supply. Our team works tirelessly to bring therapies that matter to patients who need them.
The unique ARTBIO approach selects the optimal alpha-precursor isotope (212Pb) and tumor-specific targets to create therapeutics with the potential for the highest efficacy and safety. The company's AlphaDirect™ technology, a first-of-its-kind 212Pb isolation method, enables a distributed manufacturing approach for the reliable production and delivery of ARTs. ARTBIO is advancing multiple pipeline programs, with lead program AB001 currently in first-in-human trials. The company is shaped by a long-standing scientific legacy with nearly a century of pioneering work in radiation therapy conducted at the University of Oslo and Norway’s Radium Hospital.
Cancer is relentless. So are we. We are driven by a desire to do better for cancer patients, lowering the burden of toleration and safety while at the same time raising the bar on clinical efficacy and duration. As an emerging, global biotech with locations in Boston, Basel, London, and Oslo, we take advantage of diverse scientific depth and insights, which makes ARTBIO a unique place to work.
ARTBIO is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
If interested, please apply and send your CV to [email protected]. All inquiries are treated confidentially.
ARTBIO does not accept unsolicited resumes from external agencies or recruiters. Submission of a resume without a prior written agreement does not create any express or implied contract between ARTBIO and the agency. ARTBIO will not pay any fees related to unsolicited resumes.
Channeling Energy. Changing Lives.
Cancer is relentless. So are we. ARTBIO redefines cancer care by discovering and developing a new class of Alpha Radioligand Therapies (ARTs), powered by unique Pb-212 isotope technology and seamless supply. Our team works tirelessly to bring therapies that matter to patients who need them.
Offices: Kendall Sq, c/o Alexandria LaunchLabs B200, Suite 001, Cambridge, Massachusetts 02139, US · Gaustadalléen 21, Oslo Science Park, Oslo, 0349, NO · Aeschengraben 9, Basel, BS 4051, CH · 77 New Cavendish Street, The Harley Building, London, England W1W 6XB, GB · 62 Lygon St, Suite 1, Level 3, Carlton, Victoria 3053, AU
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