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$120k–$150k/yr
Full-time
bachelor degree
Health Care Plan, Retirement Plan, Life Insurance, Paid Time Off, Family Leave, Short Term Disability
Posted 7d ago
~40 hrs/week
Responsibilities
The Clinical Trial Manager will oversee the day-to-day execution of oncology clinical trials, including site selection, start-up, and maintenance. They will serve as the primary operational contact for CROs and vendors while ensuring adherence to regulatory requirements and study timelines.
Requirements
Candidates must have a bachelor's degree in a scientific or healthcare field and 3-4 years of experience in clinical trial or project management. Strong knowledge of ICH-GCP guidelines and experience with oncology studies are required.
Full job description
Frontier Medicines is seeking two Clinical Trial Managers to support the day-to-day execution of our oncology clinical trials as they advance through clinical development. Working under the guidance of our Director/Sr. Director, Clinical Operations, you will serve as a key operational contact for our CROs and trial sites, helping drive feasibility assessments, site selection, start-up, maintenance, and close-out.
This is a great opportunity for someone who wants hands-on ownership of trial execution at a growing, clinical-stage biotech, with direct exposure to program strategy and cross-functional leadership. This is a hybrid role based in our Boston, MA office, with an expectation of 2-3 days per week onsite, plus periodic travel to trial sites and CRO/vendor meetings as needed.
What will you be doing?
● Support day-to-day activities within one or more clinical trials, including country/site feasibility assessments, site selection, start-up, maintenance, and close-out.
● Serve as a key operational point of contact for CROs and trial sites, identifying and escalating potential issues as needed.
● Assist with oversight of CRO and vendor set-up, liaising with CROs to ensure timely study initiation.
● Review site-level regulatory documents (e.g., Informed Consent Forms, essential documents) and escalate to appropriate stakeholders as needed.
● Help ensure inspection readiness, TMF quality, and adherence to protocol and regulatory requirements.
● Proactively identify potential operational challenges and, in partnership with senior team members, propose mitigation plans to keep study execution on track.
● Assist with review of protocols, master template informed consent forms, case report forms, and other clinical study documents as needed.
● Monitor study performance metrics, timelines, and deliverables, and review CRO trip reports for trends and quality issues.
● Track study budgets and vendor invoices/change orders in partnership with Clinical Operations and Finance, flagging discrepancies as needed.
● Help maintain timely and accurate study registration and updates on ClinicalTrials.gov and other applicable registries.
● Coordinate Clinical Trial Team meetings and drive action item follow-up.
● Maintain clinical operations trackers, databases, and document repositories.
● Provide regular study updates to internal stakeholders and support enrollment, database lock, and study closeout activities.
Traits we believe make a strong candidate:
● Bachelor's degree in a scientific, healthcare, or related field, or an RN, required.
● 3-4 years of Clinical Trial Manager or Clinical Project Management experience, ideally supporting oncology clinical trials.
● Strong working knowledge of ICH-GCP guidelines and clinical trial regulations.
● Excellent organizational, problem-solving, and time management skills, with strong attention to detail.
● Strong written and verbal communication skills with a collaborative, team-oriented approach.
● Comfortable in a fast-paced, dynamic environment; a proactive, roll-up-your-sleeves mindset.
● Legally authorized to work in the United States.
Health Care Plan (Medical, Dental & Vision)
Retirement Plan (401k, IRA)
Life Insurance (Basic, Voluntary & AD&D)
Paid Time Off (Vacation, Sick & Public Holidays)
Family Leave (Maternity, Paternity)
Short Term & Long Term Disability
Training & Development
Free Food & Snacks
Wellness Resources
Stock Option Plan
At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $120,000 - $150,000 Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.
This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.
Frontier Medicines is a biopharmaceutical company that “drugs the undruggable” to transform patients’ lives.
Industry
Biotechnology Research
Company size
51-200 employees
Founded
2018
Headquarters
South San Francisco, CA
LinkedIn followers
21,758
Total funding
$256M
Frontier Medicines, located in South San Francisco, CA and Boston, MA, is a precision medicine company that has pioneered a powerful discovery and development platform designed to generate medicines against disease-causing proteins previously considered undruggable. We are deploying our technologies in chemoproteomics, covalent drug discovery, and machine learning to develop a pipeline of groundbreaking medicines against the most important drivers of disease. Our lead program targets both the activated and inactive forms of KRAS G12C, a validated driver in a number of cancers that until recently has been undruggable. Our pipeline embodies our vision of bolding advancing science to defeat disease, starting with cancer.
Offices: South San Francisco, CA 94080, US · 451 D Street, Suite 207, Boston, MA 02210, US
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