Locus Biosciences, Inc.Durham, North Carolina, United States · On-site
Locus Biosciences is seeking a highly motivated and entrepreneurial applicant to join our company in a full-time, entry-level position that will rotate between our Chemistry, Manufacturing and Controls (CMC) and Research…
Skills: Molecular Biology, Microbiology, Bioprocess Development, Aseptic Technique, NGS Library Preparation
Rosemont, Illinois, United States · Remote OK
$111k–$310k/yr
Are you interested in joining a team trying to build intelligent connections across the healthcare ecosystem to enable smarter decisions that reduce costs and drive better patient outcomes? We leverage our unparalleled e…
Skills: Business Development, Consultative Sales, Account Management, Pipeline Management, Contract Negotiation
Roseville, California, United States · Hybrid
$152k–$349k/yr
Principal Cloud Developer This role has been designed as 'Hybrid' with a requirement that you will work on average 2 days per week from an HPE office. Who We Are: Hewlett Packard Enterprise is the global edge-to-cloud co…
Skills: Python, Java, Golang, JavaScript, Software Systems Design
GRAILSunnyvale, California, United States · Hybrid
$169k–$224k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Software Architecture, Distributed Systems, Cloud Computing, Java, Python
GRAILDurham, North Carolina, United States · On-site
$94k–$125k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Lean Methodologies, Six Sigma, Kaizen, Statistical Process Control, Data Visualization
Novi, Michigan, United States · Remote OK
As the Vice President of Commercial Strategies and Initiatives, you will play a pivotal leadership role in shaping the future of value-based care. In this high-impact executive position, you will drive Aledade’s growth, …
Skills: Healthcare Strategy, Product Development, Go-To-Market Strategy, Value-Based Care, Operational Execution
GRAILDurham, North Carolina, United States · On-site
$69k–$93k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Lean Methodologies, Six Sigma, Kaizen, Statistical Process Control, Data Analysis
Oakland, California, United States · Hybrid
$91k–$210k/yr
Clorox is the place that’s committed to growth – for our people and our brands. Guided by our purpose and values, and with people at the center of everything we do, we believe every one of us can make a positive impact o…
Skills: Performance Marketing, Data Visualization, Financial Acumen, Cross-Functional Communication, Retail Media Optimization
GRAILDurham, North Carolina, United States · On-site
$33/hr–$39/hr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Next-Generation Sequencing, Molecular Biology, Post-Analytical Data Review, Clinical Genomics, LIMS
GRAILDurham, North Carolina, United States · On-site
$33/hr–$39/hr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Next-Generation Sequencing, Molecular Biology, Post-Analytical Data Review, Clinical Genomics, LIMS
GRAILDurham, North Carolina, United States · On-site
$146k–$194k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Project Management, Cross-functional Coordination, Operational Readiness, Issue Tracking, Process Documentation
GRAILDurham, North Carolina, United States · On-site
$69k–$93k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Lean Methodologies, Six Sigma, Kaizen, Statistical Process Control, Data Analysis
GRAILDurham, North Carolina, United States · Hybrid
$86k–$106k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Data Collection, Data Transformation, Data Validation, Exploratory Data Analysis, Data Visualization
Glendale, Arizona, United States · On-site
$45k–$113k/yr
Job Overview Responsible to perform spirometry and other Pulmonary function tests overread for records received from trial sites as per study specific requirements and latest ATS/ERS Guidelines . Job Responsibilities: • …
Skills: Spirometry, Pulmonary Function Testing, Respiratory Physiology, ATS/ERS Guidelines, Proficiency Review
Rosemont, Illinois, United States · On-site
$81k–$203k/yr
IQVIA Digital powers exceptional brand experiences, delivering innovative solutions based on a customer-first, insights-driven, and integrated omnichannel vision. We provide authenticated, enhanced data and analytics, in…
Skills: Technical Delivery Project Management, Email Marketing, Agile Methodologies, Scrum, Jira
Durham, North Carolina, United States · On-site
Labcorp is a global leader in laboratory services, providing the insights and answers that help healthcare providers, patients, researchers, pharmaceutical companies and health systems make confident decisions and improv…
Skills: Java, Spring Boot, AWS, Angular, PostgreSQL
Burlington, North Carolina, United States · Hybrid
Labcorp is a global leader in laboratory services, providing the insights and answers that help healthcare providers, patients, researchers, pharmaceutical companies and health systems make confident decisions and improv…
Skills: EDI, HL7, FHIR, ANSI X12, Revenue Cycle Management
Durham, North Carolina, United States · On-site
At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advanc…
Skills: Practice Operations, Performance Management, Strategic Thinking, Financial Acumen, Executive Communication
Santa Clara, California, United States · On-site
$200k–$500k/yr
Role Overview We are looking for a Performance Modeling Architect who will develop the modeling and simulation frameworks used to guide architectural decisions across our platform. In this role, you will build models tha…
Skills: Computer architecture, Performance modeling, System architecture, Simulation frameworks, Python
Kirkland, Quebec, Canada · Remote OK
$110k–$274k/yr
Senior Consultant, Evidence Synthesis, Indirect Treatment Comparison (ITC) Location: Remote OVERVIEW Senior Consultants are project delivery leaders who are responsible for implementing methodologically rigorous evidence…
Skills: Indirect Treatment Comparison, Network Meta-Analysis, R Programming, Bayesian Analysis, Evidence Synthesis
Locus Biosciences, Inc.
Durham, North Carolina, United States • On-site
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The role involves rotating between CMC and R&D departments to support formulation and process development, including the operation of bioreactors and automated workflows. Responsibilities also include molecular biology experiments, microbiology culturing, and assisting in the preparation of regulatory CMC documents.
Candidates must hold a technical certificate or a degree (Bachelor's to Master's) in Biology, Chemistry, or a related field with laboratory experience. Proficiency in general lab techniques, technical writing, and the ability to work in a fast-paced collaborative environment are required.
Locus Biosciences is seeking a highly motivated and entrepreneurial applicant to join our company in a full-time, entry-level position that will rotate between our Chemistry, Manufacturing and Controls (CMC) and Research & Development (R&D) departments during this 2 year rotational program. This position is well suited for those looking for an entry-level position that is excited to learn all aspects of biotechnology drug development from early-stage research through drug product manufacturing. Candidates will be expected to accomplish defined work, as well as assist in approaching and solving complex scientific problems. Candidates should have demonstrated laboratory or manufacturing experience, with solid communication, technical aptitude, and problem-solving skills. Experience working in regulated, pharmaceutical/biotechnology R&D (GDP, GLP) and/or manufacturing environments (cGMP) is strongly preferred, but not required.
Change the future of medicine and address a serious and unmet patient need by developing completely novel therapeutic modalities.
Fast-track your career by tackling large & meaningful projects and learning a breadth of techniques and skillsets in the wet lab and manufacturing suites
Work with a team of exceptionally talented and hardworking individuals while striving to achieve a common mission
Partner with the most highly respected pharmaceutical companies in the world
Bonus pool eligibility
Health, dental, vision, life insurance, 401(k), and PTO
Free access to fitness center and classes
Designing and/or executing formulation development activities
Designing and/or executing bench-scale process development activities, including set-up and operation of development-scale bioreactors, filter trains, tangential flow filtration (TFF) equipment, and chromatography equipment
Development of analytical strategies to inform formulation and process development activities
Design and deploy automated workflows for molecular biology and microbiology assays, including liquid handling automation, next-generation sequencing (NGS) library preparation, and high-throughput screening of phage activity to accelerate research timelines and improve experimental reproducibility.
Support the development of data infrastructure and bioinformatics pipeline for R&D and CMC operations, including DNA sequence analysis, sequence assembly, and comparative genomic analysis.
Molecular biology and synthetic biology– Cloning, NGS library preparation, characterization of novel genetic engineering tools, and generation and analysis of novel engineered phage clones
Microbiology – Culturing both aerobic and obligate anaerobic organisms. Utilizing a range of bacterial strains to produce and characterize activity of phage
Independent management, planning, and execution of multiple projects, including reviewing, interpreting, and recording results.
Supporting tech transfer of new products and processes to ensure smooth transition from R&D to process development to GMP manufacturing
Forming strong relationships with all stakeholders, including technicians, associates, project and program managers, and scientists to enable successful tech transfer
Supporting Scientists in all aspects of pharmaceutical development
Assisting in the preparation of batch records, protocols, SOPs, deviations, technical reports, presentations, and other CMC documents to support drug development, including INDs, BLAs, and other applications
Gaining aseptic gowning and fill qualification
Performing material handling and staging
Practicing real-time documentation (such as batch records) during production run and maintain accurate records/logs according to GDP
Supporting Qualification and Validation activities
Identifying, communicating, and troubleshooting process issues
Supporting team effort in the effective and timely completion of root cause investigations and CAPA
Supporting a high-performance teamwork environment
Research and Development including but not limited to phage discovery, phage engineering, and strain engineering.
High Throughput Development (Automation)
Bioinformatics
Material Sciences & Technology
cGMP Manufacturing
Analytical Development
Quality Control
Clinical Lab
Quality Assurance
Project Management Office
Clinical Operations
Technical certificate or degree (e.g. BTEC Biomanufacturing), or graduation from an accredited college/university with a Bachelor’s to a Master’s degree in Biology, Chemistry, Biochemistry, Chemical Engineering, Biophysics, Pharmaceutical Technology or related field, with some lab experience (required)
Familiarity with general laboratory techniques such as pipetting, serial dilutions, aseptic technique and proper decontamination procedures
Experience in research, pharmaceutical, biotechnology, and/or sterile production environment
Experience executing SOPs and documenting work
Strong mechanical aptitude
Excellent oral and written communication skills
Technical writing ability
Thrives in a fast-paced, entrepreneurial and collaborative environment. Openly shares knowledge/information needed to accomplish a task or solve a problem
At least two years’ experience between academic or industry research
Experience in biologics (upstream, downstream, aseptic fill/finish) with working knowledge of FDA regulations and GMP systems
Experience with DNA sequence analysis, including homology searching, sequence assembly and primer design
Ability to assist in the design of experiments and interpretation of results
Motivation to learn new processes that contribute to the company's overall desire to get products into the clinic
Technical proficiency with designing and executing standard molecular biology experiments (PCR, transformation, Gibson cloning)
Experience with microbiology skills like growth curves, anaerobic microbiology, streaking and banking strains
*The level of the position will be based on the successful candidate’s qualifications.
Locus Biosciences is a clinical-stage biotechnology company developing precision antibacterial products to address critical unmet medical needs in treating bacterial infections and microbiome indications. The Locus platform engineers bacterial viruses called bacteriophages to specifically kill target pathogens while leaving non-target bacteria (i.e., the rest of the patient’s microbiome) unharmed and to deliver biotherapeutic payloads to the body sites where they are needed. Locus’s lead program is an engineered bacteriophage product targeting Escherichia coli bacteria in the urinary tract, currently being tested in an active Phase 2/3 clinical trial. Locus has collaborations with BARDA and CARB-X to develop engineered bacteriophage products targeting E. coli infections and Klebsiella pneumoniae infections, respectively. For more information about Locus visit https://www.locus-bio.com/
Job Type: Full-time, onsite
Job Location: Research Triangle Park, North Carolina
Direct applicants only. No agencies please.
Locus Biosciences, Inc. is a biotechnology company that develops precision, engineered bacteriophage products.
Locus Biosciences is a clinical-stage biotechnology company developing engineered bacteriophage products to address critical unmet medical needs in bacterial infections and immunology. The LOCUS platform combines predictive artificial intelligence and automated robotics to deliver optimized precision phage therapies that specifically kill target pathogens while leaving non-target bacteria (i.e., the rest of the patient’s microbiome) unaffected. Locus has strong backing from partners, having signed contracts with BARDA and CARB-X. The company recently completed the open-label portion of a Phase 2 trial assessing LBP-EC01 for the treatment of uncomplicated UTIs caused by drug-resistant E. coli.
Offices: 523 Davis Dr, Morrisville, North Carolina 27560, US
Based on 256 listings with disclosed salaries, most data & analytics jobs in Durham, NC pay between $79k–$273k per year. Individual offers vary with seniority, company size, and specialization.
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