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As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analy…
Skills: Oligonucleotide Drug Discovery, ASO/siRNA Design, RNA Therapeutics, Drug Target Validation, Mechanism-of-Action Studies
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San Francisco, California, United States • Remote OK
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Contribute to the technical approach of teaching AI agents to handle complex drug discovery and development data. Work across end-to-end workflows from instrument outputs to scientific decisions regarding genetic targets and drug design.
Requires 3+ years of hands-on experience with oligonucleotide or RNA therapeutics and expertise in drug target validation. Proficiency in AI agent use and familiarity with preclinical PK/PD and knockdown screening is necessary.
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights. We're seeking a BioEngineer for Oligonucleotide Discovery to join our therapeutics bench, working at the frontier of what artificial intelligence can achieve in biology.
You will contribute to our technical approach to teaching agents how to understand and handle complex drug discovery and development data, working across end-to-end workflows from instrument outputs and experimental readouts to real scientific decisions. You will work as part of a team of software engineers, biologists, and drug hunters building datasets to teach these agents to reason better across:
Genetic target and MoA selection
ASO/siRNA drug design
Screening and functional characterization
Pharmacology
3+ years hands-on experience with oligonucleotide (ASO/siRNA), RNA therapeutics, or related
Experience in drug target validation or mechanism-of-action studies using functional or population genomics
Familiarity with drug discovery and development workflows — sequence design, knockdown screening, or preclinical PK/PD
Proficiency in AI agent use
OTE 120k - 180k, performance based, based on individual's expertise
Free meals (lunch and dinner)
Waterfront office in China Basin, San Francisco
Full-time, in-person (can be remote)
Agent Infrastructure for Biology
Agent infrastructure for biology. Bundled with kits + machines to serve 300+ pharma, biotech and academic teams around the world.
Offices: San Francisco, CA 94103, US
