Vertex Inc.Boston, Massachusetts, United States · Hybrid
$167k–$250k/yr
Job Description Job Summary The Principal Engineer, VaiDA Mobile Experience will help bring Vertex’s AI experience tool, VaiDA, to life through intuitive, high-quality mobile experiences that make AI accessible wherever …
Skills: Mobile application development, iOS development, Android development, API integration, Secure mobile development
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$167k–$250k/yr
Job Description Position Summary Vertex is seeking an AI Full-Stack Engineer to create the next generation of AI-powered applications and agents that deliver practical value across internal and user-facing experiences. T…
Skills: Large language model application development, Agentic workflow design, Prompt engineering, API integration, Multi-step workflow automation
Boston, Massachusetts, United States · Hybrid
$110k–$145k/yr
About LILT AI is changing how the world communicates — and LILT is leading that transformation. We're on a mission to make the world's information accessible to everyone, regardless of the language they speak. We use cut…
Skills: AI/ML Data Operations, Project Management, LLM Training, SFT, RLHF
Vertex Inc.Boston, Massachusetts, United States · Hybrid
Job Description For this Director-level role, we are seeking a scientific and technical expert to lead our agentic AI co-scientist initiative across our scientific organization. This individual will serve as the scientif…
Skills: Agentic AI, Drug discovery, Scientific leadership, Machine learning, LLMs
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$188k–$282k/yr
Job Description Vertex is seeking a Senior Principal AI Engineer to define and build the foundational enterprise AI platform that powers intelligent applications across the enterprise. This role will lead the design and …
Skills: Agentic AI, Large Language Models, RAG, Platform Engineering, Orchestration
Boston, Massachusetts, United States · Remote OK
$198k–$273k/yr
Our Mission At Palo Alto Networks®, we’re united by a shared mission—to protect our digital way of life. We thrive at the intersection of innovation and impact, solving real-world problems with cutting-edge technology an…
Skills: Pre-sales, Sales engineering, Cybersecurity, Network security, Cloud security
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$167k–$250k/yr
Job Description Position Summary Vertex is seeking a Full-Stack AI Engineer to help build, extend, and operate our Agentic AI platform end to end. In this role you will develop AI agents and the services, APIs, and inter…
Skills: Agentic AI, Platform engineering, API integration, MCP protocols, A2A protocols
Boston, Massachusetts, United States · Remote OK
$147k–$293k/yr
Intelligence Center X is Siemens' platform for the agentic enterprise The next wave of enterprise software isn't about writing more code — it's about giving organizations the tools to combine trusted data, AI, and applic…
Skills: Solutions architecture, Enterprise AI, Knowledge graphs, Agentic applications, Technical leadership
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$167k–$250k/yr
Job Description Position Summary Vertex is seeking an AI Full-Stack Engineer to create the next generation of AI-powered applications and agents that deliver practical value across internal and user-facing experiences. T…
Skills: Large language model application development, Agentic workflow design, Prompt engineering, API integration, Multi-step workflow automation
Boston, Massachusetts, United States · Remote OK
$147k–$293k/yr
Intelligence Center X is Siemens' platform for the agentic enterprise The next wave of enterprise software isn't about writing more code — it's about giving organizations the tools to combine trusted data, AI, and applic…
Skills: Solutions architecture, Enterprise AI, Knowledge graphs, Agentic applications, Technical leadership
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$160k–$240k/yr
Job Description General Summary: Vertex is entering a transformative phase in its data journey—where trusted, governed master data is foundational to enabling enterprise-wide analytics, AI, and operational excellence. We…
Skills: Master Data Management, Data Governance, Cloud Migration, Data Modeling, Reltio
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$167k–$250k/yr
Job Description Principal Engineer, VaiDA User Experience Location: Hybrid / On-site Vertex Pharmaceuticals is a global biotechnology company that invests in scientific innovation to create transformative medicines for p…
Skills: React, Angular, TypeScript, JavaScript, HTML
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$143k–$214k/yr
Job Description General Summary: Vertex is seeking a Principal Analyst, G&A Technology to support our Legal, OBIE, and Corporate Communications functions. In this role, you will partner closely with stakeholders to deliv…
Skills: Technology delivery, Stakeholder engagement, Cross-functional leadership, Project management, Risk management
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$166k–$250k/yr
Job Description General Summary: The Chemistry Manufacturing Controls (CMC) Associate Director leads and executes global regulatory CMC strategies across investigational and commercial products focusing on biologics. Thi…
Skills: Regulatory CMC, Biologics, Regulatory strategy, Health Authority interactions, Lifecycle management
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$104k–$156k/yr
Job Description General Summary This role is an early-career technical position supporting software (Model N) used across pricing, contracting, market access, government spend transparency reporting, gross-to-net, revenu…
Skills: Software Development Lifecycle, Model N, Technical Configuration, Agentic AI, Systems Analysis
Boston, Massachusetts, United States · On-site
$90k–$130k/yr
POSITION SUMMARY: Oversees a team of analysts responsible for the coordination, training and implementation of Epic Willow Ambulatory. The primary responsibility is to ensure that applications are well supported and that…
Skills: Epic Willow Ambulatory, Team leadership, Project management, Clinical workflows, Medical terminology
Boston, Massachusetts, United States · On-site
What you will do Conduct interviews with Red Hat partners, solution architects, and field sales teams to uncover the most pressing customer AI use cases Analyze and synthesize findings to identify patterns, opportunities…
Skills: Analytical skills, Research, Communication, Presentation skills, Data synthesis
Boston, Massachusetts, United States · On-site
$39k–$111k/yr
Job Description The Future Talent Program features internships that last up to 12 weeks and will include one or more projects. These opportunities in our Research and Development Division can provide you with great devel…
Skills: Data Science, Python, R, MATLAB, Image Processing
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$143k–$214k/yr
Job Description General Summary: The Business Engagement & Technology Principal Analyst will be a technical resource in ensuring delivery and support of commercial-off-the-shelf (COTS) and a wide range of custom solution…
Skills: Project management, Business analysis, Solution design, System lifecycle management, Agile methodology
Vertex Inc.Boston, Massachusetts, United States · Hybrid
$168k–$252k/yr
Job Description Vertex is seeking a scientific leader to accelerate the application of AI and agentic systems across drug discovery. Working at the intersection of Computational Drug Design, project teams, Data & Methods…
Skills: Computational chemistry, Cheminformatics, AI-driven drug discovery, Agentic systems, Small-molecule drug discovery
Vertex Inc.
Boston, Massachusetts, United States • Hybrid
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The Principal Engineer will design, build, and maintain high-quality mobile applications for the VaiDA AI experience while owning the technical architecture. They will also coordinate mobile deployments and ensure seamless integration between mobile interfaces and Vertex's AI and agentic platforms.
Candidates must have a bachelor's degree in a technical field and professional experience developing secure, performant mobile applications for iOS and Android. Strong problem-solving skills and the ability to collaborate across cross-functional teams to deliver intuitive mobile workflows are essential.
The Principal Engineer, VaiDA Mobile Experience will help bring Vertex’s AI experience tool, VaiDA, to life through intuitive, high-quality mobile experiences that make AI accessible wherever work happens. This role will design and develop secure, performant, and user-friendly mobile capabilities that connect seamlessly to Vertex’s AI and agentic platform, while also supporting existing mobile applications across Vertex. The ideal candidate combines strong mobile engineering expertise with a sharp eye for usability, polish, and responsiveness, and can translate complex AI-driven functionality into clear, elegant mobile interactions. This person will play a key role in making VaiDA a trusted and valuable everyday companion for Vertex employees.
Work Model: Hybrid or On-site
Vertex offers a competitive and comprehensive rewards package designed to support employees’ health, well-being, growth, and success. Benefits may include:
#LI-HYBRID
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
When it has to be right, you Vertex™.
Vertex is the Decision-to-Defense™ global indirect tax and compliance company. We help enterprises control indirect tax and compliance across the transaction lifecycle-so outcomes can be proved and improved with confidence. Our purpose is to ensure businesses and communities thrive through trusted transactions. Global compliance now lives inside the transaction. So does Vertex-helping enterprises prove outcomes from determination to defense.
Offices: 2301 Renaissance Blvd, King of Prussia, PA 19406, US · 40 Shuman Blvd., Suite 218, Naperville, IL 60540, US · 1 Furzeground Way, Stockley Park, Stockley Park, Uxbridge UB11 1EZ, GB · 101 Arthur Andersen Parkway, Suite 300, Sarasota, FL 34232, US · Gustav Mahlerplein, Amsterdam, North Holland 1082, NL
Based on 3159 listings with disclosed salaries, most technology jobs in Boston, MA pay between $90k–$220k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 3,928 open technology positions in Boston, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Amazon, WHOOP, State Street, Liberty Mutual Insurance, Vertex Inc., among others. Browse the listings above to see every active employer.
Yes — 2278 of the 3928 open technology positions offer remote or hybrid work (563 remote, 1715 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
