Software Jobs in Cambridge, MA (Now Hiring) — 433 open — Page 5

Machine Learning Applied Researcher - Speech, Vision and Audio

Cambridge, Massachusetts, United States · On-site

Senior$11B raised

Imagine what you could do here. At Apple, new ideas have a way of becoming extraordinary products, services, and customer experiences very quickly. Bring passion and dedication to your job and there's no telling what you…

Skills: Machine Learning, Deep Learning, Pytorch, Self-supervised Learning, Synthetic Data Generation

Machine Learning Applied Researcher - Speech, Vision and Audio

Cambridge, Massachusetts, United States · On-site

Senior+$11B raised

Imagine what you could do here. At Apple, new ideas have a way of becoming extraordinary products, services, and customer experiences very quickly. Bring passion and dedication to your job and there's no telling what you…

Skills: Machine Learning, Deep Learning, Pytorch, Self-supervised Learning, Synthetic Data Generation

Senior II Security Architect

Cambridge, Massachusetts, United States · Remote OK

$139k–$251k/yr

Senior$5.2B raised

Would you enjoy working with cutting-edge web security systems? Does the opportunity to make a difference at a leading technology organization excite you? Join our Micro Segmentation Professional Services team With our c…

Skills: Network segmentation, Security architecture, Data center infrastructure, Cloud security, Project management

Senior Software Engineer, Computational Policy Lab

Cambridge, Massachusetts, United States · Hybrid

Senior

Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…

Skills: Software engineering, Generative AI, Data science, Machine learning, Natural language processing

Principal Engineer, Service Networking AI

Sunnyvale, California, United States · On-site

$307k–$427k/yr

Senior+$26M raised

Minimum qualifications: Bachelor's degree in Computer Science or a related field, or equivalent practical experience. 15 years of software engineering experience, building and working with large-scale distributed systems…

Skills: Distributed Systems, Networking, AI Infrastructure, Kubernetes, Layer 7 Protocols

Pioneering Intelligence: Agentic AI Co-Op

Cambridge, Massachusetts, United States · On-site

$25/hr–$45/hr

Entry level$9.1B raised

Who We Are Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemb…

Skills: Python, Machine learning, Agentic AI, Software development, API integration

Principal Data Scientist

Cambridge, Massachusetts, United States · On-site

$179k–$237k/yr

Senior$9.1B raised

COMPANY DESCRIPTION Extuitive is a Flagship Pioneering–backed startup reimagining product innovation for the AI era. Our mission is to revolutionize go to market for planning and execution for the agentic age. Based in C…

Skills: Python, SQL, Machine learning, Statistics, Experimental design

Principal Backend Engineer

Cambridge, Massachusetts, United States · On-site

$188k–$259k/yr

Senior+$9.1B raised

COMPANY DESCRIPTION Extuitive is a Flagship Pioneering–backed startup reimagining product innovation for the AI era. Our mission is to revolutionize go to market for planning and execution for the agentic age. Based in C…

Skills: Backend engineering, Node.js, TypeScript, Go, Python

(Senior) Scientist, Machine Learning

Cambridge, Massachusetts, United States · On-site

$132k–$259k/yr

Mid level$9.1B raised

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? COMPANY DESCRIPTION Expediti…

Skills: Machine Learning, Quantum Chemistry, Generative Molecular Design, Python, PyTorch

Director, Research AI

Cambridge, Massachusetts, United States · Hybrid

$193k–$290k/yr

Senior+$4.5B raised

Overview Alnylam Pharmaceuticals is seeking a highly technical and strategic Director of Artificial Intelligence to lead the expansion of AI capabilities across the Research organization. This role will establish and lea…

Skills: Artificial Intelligence, Computational Biology, Agentic AI, Machine Learning, Python

Research Scientist, Photonic Materials Discovery

Cambridge, Massachusetts, United States · On-site

$176k–$304k/yr

Senior$551M raised

Your Impact at LILA We are seeking a computational materials scientist to discover and optimize materials for electro-optic and photonic technologies. The role centers on understanding how composition, structure, defects…

Skills: Computational materials science, Density functional theory, Electronic-structure calculations, Python, HPC

Staff Research Engineer, Scientific Computing and ML/Physics Infrastructure

London, England, United Kingdom · On-site

$224k–$294k/yr

Senior$551M raised

Your Impact at LILA Lila Sciences is seeking a Research Engineer, Scientific Computing and ML/Physics Infrastructure to help turn promising research tools into robust, scalable systems. This role bridges research and pro…

Skills: Python, Machine learning, Scientific computing, Distributed systems, GPU computing

Finance Business Partner, AI & Software

Cambridge, Massachusetts, United States · On-site

Senior$551M raised

Your Impact at LILA Lila Sciences is scaling its Scientific Superintelligence platform, and we’re building the finance backbone to match. As the Finance Business Partner for our AI/ML and Infrastructure teams, you’ll par…

Skills: Financial Planning and Analysis, Strategic Finance, Cloud Economics, Cost Modeling, GPU Infrastructure

Manager / Senior Manager, Enterprise GTM, Chemicals

Cambridge, Massachusetts, United States · On-site

$88k–$144k/yr

Mid level$551M raised

Your Impact at LILA We are seeking an Enterprise Account Lead, Chemicals to define how Fortune 500 energy, manufacturing, and chemical companies engage with the world's first platform for scientific superintelligence. Yo…

Skills: Enterprise sales, Account management, Business development, Technical sales, Chemistry

Scientist II / Senior ML Scientist, Cofolding and Structure-Aware ML

London, England, United Kingdom · On-site

$228k–$358k/yr

Senior$551M raised

Your Impact at LILA Lila Sciences is seeking a Machine Learning Scientist, Cofolding and Structure-Aware ML to train next-generation cofolding models for drug discovery. This role is focused on improving models that reas…

Skills: Machine learning, Deep learning, Cofolding, Protein-ligand modeling, Representation learning

Research Product Manager, Fine-tuning

San Francisco, California, United States · On-site

$204k–$310k/yr

Senior$551M raised

Your Impact at LILA You'll own two connected but distinct areas. First, you'll decide which new scientific domain capabilities the Lila model should gain and how to build them — the right mix of reinforcement-learning en…

Skills: Product management, Machine learning, Artificial intelligence, LLM training, Fine-tuning

Manager / Senior Manager, Enterprise GTM, Materials

Cambridge, Massachusetts, United States · On-site

$88k–$144k/yr

Mid level$551M raised

Your Impact at LILA We are seeking an Enterprise Account Lead, Materials to define how Fortune 500 energy, manufacturing, and materials companies engage with the world's first platform for scientific superintelligence. Y…

Skills: Enterprise sales, Account management, Pipeline management, Revenue forecasting, Technical sales

Scientist II / Senior ML Scientist, Data-Efficient Learning for Drug Discovery

London, England, United Kingdom · On-site

$228k–$358k/yr

Senior$551M raised

Your Impact at LILA Lila Sciences is seeking a Machine Learning Scientist, Data-Efficient Learning for Drug Discovery to build models and learning strategies for settings where data is scarce, expensive, and intentionall…

Skills: Machine learning, Data-efficient learning, Drug discovery, Active learning, Meta-learning

Senior Technical Program Manager, Robotics

Cambridge, Massachusetts, United States · On-site

$192k–$238k/yr

Senior$551M raised

Your Impact at LILA You will be the program owner for Physical AI — the shared infrastructure our autonomous labs run on. Working across multiple engineering teams, you'll turn the platform roadmap into a sequenced, depe…

Skills: Technical program management, Infrastructure software, Dependency management, Risk management, Reliability engineering

Scientist II/Senior Scientist, Computational Biophysics

London, England, United Kingdom · On-site

$141k–$218k/yr

Senior$551M raised

Your Impact at LILA Lila Sciences is seeking a Computational Biophysics Scientist to help ensure that our AI agents can use biophysics tools in ways that are scientifically correct, reliable, and useful for drug discover…

Skills: Computational biophysics, Molecular dynamics, MM/GBSA, Free-energy perturbation, RBFE

Frequently asked questions

How much do Software jobs in Cambridge, MA pay?

Based on 358 listings with disclosed salaries, most software jobs in Cambridge, MA pay between $100k–$251k per year. Individual offers vary with seniority, company size, and specialization.

How many Software jobs are open in Cambridge, MA right now?

There are currently 433 open software positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.

Which companies are hiring for Software roles in Cambridge, MA?

Companies currently hiring include Akamai Technologies, Lila Sciences, Google, MORSE Corp, Draper, among others. Browse the listings above to see every active employer.

Are there remote or hybrid Software jobs in Cambridge, MA?

Yes — 211 of the 433 open software positions offer remote or hybrid work (68 remote, 143 hybrid).

How do I apply for Software jobs in Cambridge, MA?

Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.