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$160k–$180k/yr
Full-time
bachelor degree, postgraduate degree
Posted 10d ago
~40 hrs/week
Responsibilities
Oversees the MSAT team in executing technical transfers from process development to large-scale biologics manufacturing. Provides technical leadership and problem-solving support for cGMP operations to ensure product supply and regulatory compliance.
Requirements
Requires a Bachelor's degree in Life Sciences or Engineering with 5+ years of experience in Biologics Manufacturing or MSAT. Must have at least 3 years of people management experience and expertise in either upstream or downstream processing.
Full job description
With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing.
Forward-thinking and committed, we find the best solution and use the right technologies to design, develop and manufacture your products to ensure we get vital medicines to patients quickly and safely.
We are dedicated to quality excellence. We are driven to get better treatments to market, efficiently and responsibly by reducing timelines and delivering the highest quality products and services.
We are Abzena. More than a CDMO, we are a responsible and dedicated partner that takes care of your products from concept to patient.
The Manager of Manufacturing Sciences and Technology (MSAT) is a technical leadership position that directly supports product supply, strategic objectives, and client programs for Biologics manufacturing. Under the leadership of the MSAT Manager, the MSAT team is responsible for technical and process support of clinical cGMP Manufacturing using multiple production platforms. The scope of support includes ensuring smooth and efficient technical transfers into manufacturing, documentation and technical writing, advanced troubleshooting of complex problems, and continuous improvement. This position is also responsible for maintaining a safe work environment in compliance with CAL OSHA and other local, state, and federal regulatory agencies.
Shift B: 10 hour shifts, Wednesday through Saturday
\nResponsibilities
Oversees and supports MSAT staff in executing tech transfer from PD to large-scale biologics manufacturing. In some cases, will directly support in this capacity, as needed.
Oversees MSAT staff supporting on-the-floor cGMP operations for cGMP production for tech-transferred programs.
Oversees and provides guidance on the implementation of new manufacturing equipment and automation solutions for cGMP production in collaboration with Process Development and Equipment Engineering.
Establishes, characterizes, and maintains cGMP manufacturing processes.
Collaborates with Quality ensuring delivery of products meets regulatory standards.
Provides ongoing technical and problem-solving support to Manufacturing Operations and Quality.
Provides a science-based and risk-based approach for the resolution of deviations, investigations and process issues through analysis of in-process, historical and scale-down data.
Develops and translates process knowledge and understanding into manufacturing controls strategy (product, process, materials, environment, etc.) to ensure successful scale up and transfer.
Supports Manufacturing to resolve complex process/product issues.
Collaborates with Process Development in the gathering and analysis of manufacturing campaign data trends for process optimization opportunities for future client work.
Qualifications
Bachelor's degree in a Life Sciences, Engineering or related discipline
Advanced degree (e.g., Master’s or PhD preferred)
5+ years of direct experience in Biologics Manufacturing, Process Development and/or MSAT
Expertise in either Upstream or Downstream Biologics Manufacturing is required
3+ years of people manager (e.g., lead, supervisor or higher) experience with ability to achieve results through teamwork and leadership of others, streamlined execution, and innovation
Leadership and communication skills
Proven track record in cGMP at scale manufacturing operations support, including problem solving and successful delivery of cross-functional technical projects
Strong scientific background and expertise in biologics products for cGMP clinical operations
Demonstrated ability to develop constructive and effective relationships with direct reports, colleagues, and senior management
Demonstrated ability to effectively communicate project tech transfer targets to meet management, customers, and staff expectations
\n
$160,000 - $180,000 a year
\n
FLSA: Exempt
Abzena is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training.
Abzena is the leading integrated bioconjugate & complex biologics CDMO+CRO, focused on rapidly moving medicines forward.
Industry
Pharmaceutical Manufacturing
Company size
501-1,000 employees
Founded
2001
Headquarters
San Diego, California
LinkedIn followers
30,039
Total funding
$139M
Abzena is the leading end-to-end bioconjugate, ADC, and complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. With the ability to tailor its strategy and customer experience to each project, Abzena develops and implements innovative solutions that enable biotech and biopharma companies to realize the full potential of their molecule and move medicines forward faster. The company has research, development, and cGMP facilities across locations in San Diego, CA, Bristol, PA, and Cambridge, UK.
Offices: 6325 Lusk Blvd, San Diego, California 92121, US · Babraham Research Campus, Babraham, Cambridge, Cambridgeshire CB22 3AT, GB · 360 George Patterson Blvd, Suite 101E, Bristol, PA 19007, US · 11425 Sorrento Valley Rd, San Diego, California 92121, US · 2858 Loker Ave E, Carlsbad, California 92010, US
Immunogenicity Assessment & Protein EngineeringCell Line Development to GMP ManufacturingADCs & GMP BioconjugationCustom Chemical SynthesisAnalytical and Bioassay SolutionsLinker PayloadsPre-FormulationProcess DevelopmentTechnology TransferIntegrated Drug Development and Manufacturing Programs
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