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Jobs at Abzena (Now Hiring) — 26 open

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MSAT Sr Engineer/Scientist - Bioconjugation

San Diego, California, United States · On-site

$150k–$170k/yr

Senior$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Bioconjugation, Antibody Drug Conjugates (ADCs), Antibody Oligonucleotide Conjugates (AOCs), Technology Transfer, cGMP Manufacturing

Abzena logoAbzena

MSAT Manager - Shift B

San Diego, California, United States · On-site

$160k–$180k/yr

Senior$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Biologics Manufacturing, Process Development, MSAT, cGMP, Tech Transfer

Abzena logoAbzena

Project Manager

Cambridge, England, United Kingdom · On-site

$54k–$59k/yr

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Project Management, Stakeholder Management, Budget Management, Resource Planning, Cross-functional Team Leadership

Abzena logoAbzena

Sr GMP Process Mechanic

Bristol, Pennsylvania, United States · On-site

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Preventative Maintenance, Corrective Maintenance, Troubleshooting, cGMP Compliance, Good Documentation Practices

Abzena logoAbzena

Manufacturing Lead, Operations - Shift B

San Diego, California, United States · On-site

$85k–$100k/yr

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Upstream Processing, Downstream Processing, cGMP Compliance, Aseptic Technique, Column Chromatography

Abzena logoAbzena

Manufacturing Associate I - Shift B

San Diego, California, United States · On-site

$50k–$65k/yr

Entry level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: cGMP, Cell Culture, Bioreactor Operation, Aseptic Technique, Chromatography

Abzena logoAbzena

Manufacturing Manager - Shift B

San Diego, California, United States · On-site

$125k–$150k/yr

Senior+$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Biologics Manufacturing, cGMP Compliance, People Leadership, Upstream Processing, Downstream Processing

Abzena logoAbzena

Manufacturing Manager - Shift A

San Diego, California, United States · On-site

$125k–$150k/yr

Senior+$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Biologics Manufacturing, cGMP Compliance, People Leadership, Upstream Processing, Downstream Processing

Abzena logoAbzena

Scientist I, Downstream Process Development

San Diego, California, United States · On-site

$110k–$135k/yr

Senior+$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Purification Process Development, Biologics, Bioconjugates, Chromatography, Tangential Flow Filtration

Abzena logoAbzena

Sr Manufacturing Associate - Shift A

Carlsbad, California, United States · On-site

$80k–$95k/yr

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Upstream Processing, Downstream Processing, cGMP Compliance, Aseptic Technique, Single-Use Technologies

Abzena logoAbzena

Sr Manufacturing Associate - Shift B

Carlsbad, California, United States · On-site

$80k–$95k/yr

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Upstream Processing, Downstream Processing, cGMP Compliance, Aseptic Technique, Single-Use Technologies

Abzena logoAbzena

Manufacturing Lead - Shift A

San Diego, California, United States · On-site

$85k–$100k/yr

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Upstream Processing, Downstream Processing, Aseptic Technique, cGMP Compliance, Column Chromatography

Abzena logoAbzena

Manufacturing Lead - Shift B

San Diego, California, United States · On-site

$85k–$100k/yr

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Upstream Processing, Downstream Processing, cGMP Compliance, Aseptic Technique, Column Chromatography

Abzena logoAbzena

Scientist I/II, Formulation Development

Cambridge, England, United Kingdom · On-site

$27k–$33k/yr

Mid level$139M raised

We have a vacancy at Scientist I/II level for a biochemist in the formulation development team of the Analytics group based in Cambridge (UK). In this lab-based role you will be working as part of a team on client-facing…

Skills: Protein Analytics, Formulation Development, SE-HPLC, IEX, CE-SDS

Abzena logoAbzena

Manufacturing Supervisor I - Shift B

San Diego, California, United States · On-site

$100k–$120k/yr

Senior$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: GMP Manufacturing, Biologics Production, Team Leadership, Upstream Processing, Downstream Processing

Abzena logoAbzena

Manufacturing Supervisor I - Shift A

San Diego, California, United States · On-site

$100k–$120k/yr

Senior$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: GMP Manufacturing, Biologics Production, Upstream Processing, Downstream Processing, Team Leadership

Abzena logoAbzena

Manufacturing Manager

Bristol, Pennsylvania, United States · On-site

Senior$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: cGMP Manufacturing, People Leadership, Operational Execution, Quality Compliance, Troubleshooting

Abzena logoAbzena

Lab Services Manager

Bristol, Pennsylvania, United States · On-site

Senior+$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Laboratory Management, GMP Compliance, Sample Operations, Team Leadership, Regulatory Inspections

Abzena logoAbzena

MSAT Engineer

Bristol, Pennsylvania, United States · On-site

Mid level$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: Bioconjugation, Technology Transfer, cGMP Manufacturing, ADC, AOC

Abzena logoAbzena

Automation Engineer

San Diego, California, United States · On-site

$100k–$140k/yr

Senior$139M raised

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we f…

Skills: PLC, DCS, SCADA, Data Historians, cGMP

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Showing 1–20 of 26

Abzena logo

MSAT Sr Engineer/Scientist - Bioconjugation

Abzena

San Diego, California, United States • On-site

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  • $150k–$170k/yr
  • Full-time
  • postgraduate degree
  • Posted 1d ago
  • ~40 hrs/week

Responsibilities

Serve as the technical bridge between process development and cGMP manufacturing for complex biologic drug conjugates. Lead technology transfers, author batch records, and drive continuous improvement initiatives to ensure process robustness and manufacturing readiness.

Requirements

Requires a PhD or MS in Biochemistry, Chemical Engineering, or a related field with over 5 years of experience in biopharma MSAT focusing on ADC or AOC processes. Must have proven expertise in GMP operations, aseptic techniques, and various chromatography and filtration methods.

Full job description

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing.

Forward-thinking and committed, we find the best solution and use the right technologies to design, develop and manufacture your products to ensure we get vital medicines to patients quickly and safely.

We are dedicated to quality excellence. We are driven to get better treatments to market, efficiently and responsibly by reducing timelines and delivering the highest quality products and services.

We are Abzena. More than a CDMO, we are a responsible and dedicated partner that takes care of your products from concept to patient.

We are seeking an experienced and highly skilled MSAT Engineer/Scientist with deep expertise in bioconjugation processes, including Antibody Drug Conjugates (ADCs) and Antibody Oligonucleotide Conjugates (AOCs), to support clinical and commercial cGMP manufacturing operations. The MSAT Engineer/Scientist will serve as the technical bridge between process development and manufacturing, ensuring successful technology transfer, manufacturing readiness, and sustained process robustness for highly potent and complex biologic drug conjugates across the product lifecycle.

\nResponsibilities
  • Adhere to all GDP, GLP, and cGMP requirements as well as Abzena policies, procedures, and mission while fulfilling duties, responsibilities, and tasks.
  • Demonstrate working knowledge of USP, 21 CFR, and ICH guidelines applicable to bioconjugation and cGMP manufacturing.
  • Serve as the MSAT subject matter expert (SME) for bioconjugation processes including ADCs and AOCs across early development through commercial lifecycle stages.
  • Provide technical leadership for technology transfer from internal or external process development teams into cGMP manufacturing, including facility fit assessments, scale up planning, and risk assessments.
  • Lead technology transfer of bioconjugation processes into cGMP manufacturing from internal teams and external development partners.
  • Author and revise cGMP batch records and master batch production documents for early phase, late phase, and commercial programs.
  • Draft and maintain cGMP documentation, including BOMs, specifications, SOPs, technology transfer documents, PFDs, and P and IDs, as required to support execution and readiness.
  • Lead or support process investigations, deviations, CAPAs, and root cause analysis related to conjugation, UF/DF, and chromatography operations.
  • Provide in-person and real-time manufacturing production support required for project success.
  • Drive continuous improvement initiatives related to process robustness, documentation, and manufacturing efficiency. Including compatibility and assembly strategy for single use components, including connector selection, weld and seal parameters, and failure modes. Drive assembly standardization across programs to reduce execution risk.
  • High potency and containment alignment, translate OEB controls into practical manufacturing requirements for equipment, PPE, waste, and cleaning. Lead cross functional reviews with EHS, Facilities, and QA for campaign readiness
  • Technical training and knowledge management. Develop training content for new processes, new equipment, and new batch record revisions. Maintain a living knowledge package per program, including lessons learned, known failure modes, and standard responses.
  • Design and implement process characterization, scale-up, and control strategies in collaboration with PD, Manufacturing, and QA/QC teams.
  • Maintain a strong working knowledge of cGMP raw materials, consumables, assemblies, in-process materials, designs, and part numbers to complete detailed cGMP records.
  • Participate in or lead PPQ campaigns, including planning, execution support, and regulatory documentation contributions.
  • Control strategy ownership, define and maintain the process control strategy, including CPP setpoints, acceptable ranges, sampling plans, and in-process controls.
  • Support regulatory inspections, client audits, and due diligence activities as the MSAT technical lead for assigned programs.
  • Contribute to cross-functional project teams to deliver clinical and commercial batches of bioconjugates on time and within scope.
  • Demonstrates technical proficiency, scientific creativity, and collaboration with others.
  • Operate to the highest ethical and moral standards.
  • Ability to multi-task, supporting multiple projects simultaneously ensuring all deadlines are on budget and on time.
  • Discuss and present manufacturing campaign data and analysis to internal project teams and respective clients
  • Perform other duties as assigned.
  • This is a senior level individual contributor position with future plans to expand into a manager level MSAT role with oversight of Bioconjugation technology transfers.
Qualifications
  • PhD or MS in Biochemistry, Chemical Engineering, Pharmaceutical Sciences, or a related discipline
  • 5+ years of experience in biopharma MSAT or technical operations, with a focus on ADC and/or AOC processes.

Knowledge

  • Proven track record in both development and commercial-stage support, including batch record authorship and process documentation.
  • Working knowledge of GMP operations, including manufacturing floor support, deviation resolution, and change control.
  • Knowledge and skill with aseptic technique required: BSC Operations, and aseptic processing, including welding/sealing and/or single use sterile connectors
  • Hands-on experience with conjugation chemistries, tangential flow filtration (TFF), Protein A, ion exchange (IEX), and hydrophobic interaction chromatography (HIC).
  • Strong understanding of Microsoft Office Suite including basic functions and graphing within Microsoft Excel
  • Familiarity with semi/fully automated manufacturing equipment
  • Proven ability to troubleshoot bioprocess operations and equipment.
  • Understanding of relevant analytical, processing, and scale-up calculations.
  • Proven ability to build, modify, and utilize digital data storage, visualization, and analysis systems/tools.
  • Strong interpersonal and communication skills, with the ability to interface effectively with cross-functional teams and clients

Preferred Qualifications:

  • Experience with Contact Development and Manufacturing Organizations (CDMOs)
  • Experience with high-potency APIs and handling OEB 4–5 level materials.
  • Familiarity with process validation (PPQ), commercial tech transfer, and lifecycle management.
  • Understanding of ICH, FDA, and EMA regulatory expectations for complex biologics and bioconjugates.
\n
$150,000 - $170,000 a year
\n

FLSA: Exempt

Abzena is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.

This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training.

Related keywords

BioconjugationADCAOCMSATcGMPGDPGLPUSP21 CFRICH GuidelinesTFFProtein AIEXHICPPQOEB 4-5

About Abzena

LinkedInVisit site

Abzena is the leading integrated bioconjugate & complex biologics CDMO+CRO, focused on rapidly moving medicines forward.

Industry
Pharmaceutical Manufacturing
Company size
501-1,000 employees
Founded
2001
Headquarters
San Diego, California
LinkedIn followers
30,039
Total funding
$139M

Abzena is the leading end-to-end bioconjugate, ADC, and complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. With the ability to tailor its strategy and customer experience to each project, Abzena develops and implements innovative solutions that enable biotech and biopharma companies to realize the full potential of their molecule and move medicines forward faster. The company has research, development, and cGMP facilities across locations in San Diego, CA, Bristol, PA, and Cambridge, UK.

Offices: 6325 Lusk Blvd, San Diego, California 92121, US · Babraham Research Campus, Babraham, Cambridge, Cambridgeshire CB22 3AT, GB · 360 George Patterson Blvd, Suite 101E, Bristol, PA 19007, US · 11425 Sorrento Valley Rd, San Diego, California 92121, US · 2858 Loker Ave E, Carlsbad, California 92010, US

Immunogenicity Assessment & Protein EngineeringCell Line Development to GMP ManufacturingADCs & GMP BioconjugationCustom Chemical SynthesisAnalytical and Bioassay SolutionsLinker PayloadsPre-FormulationProcess DevelopmentTechnology TransferIntegrated Drug Development and Manufacturing Programs
View all jobs at Abzena

About Abzena

LinkedInVisit site

Abzena is the leading integrated bioconjugate & complex biologics CDMO+CRO, focused on rapidly moving medicines forward.

Industry
Pharmaceutical Manufacturing
Company size
501-1,000 employees
Founded
2001
Headquarters
San Diego, California
LinkedIn followers
30,039
Total funding
$139M

Abzena is the leading end-to-end bioconjugate, ADC, and complex biologics CDMO + CRO. From discovery through commercial launch, we support customers with fully integrated programs or individual services designed to de-risk and streamline the development of new treatments for patients in need. With the ability to tailor its strategy and customer experience to each project, Abzena develops and implements innovative solutions that enable biotech and biopharma companies to realize the full potential of their molecule and move medicines forward faster. The company has research, development, and cGMP facilities across locations in San Diego, CA, Bristol, PA, and Cambridge, UK.

Offices: 6325 Lusk Blvd, San Diego, California 92121, US · Babraham Research Campus, Babraham, Cambridge, Cambridgeshire CB22 3AT, GB · 360 George Patterson Blvd, Suite 101E, Bristol, PA 19007, US · 11425 Sorrento Valley Rd, San Diego, California 92121, US · 2858 Loker Ave E, Carlsbad, California 92010, US

Immunogenicity Assessment & Protein EngineeringCell Line Development to GMP ManufacturingADCs & GMP BioconjugationCustom Chemical SynthesisAnalytical and Bioassay SolutionsLinker PayloadsPre-FormulationProcess DevelopmentTechnology TransferIntegrated Drug Development and Manufacturing Programs
View all jobs at Abzena

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