Pennsylvania, United States · Remote OK
$276k–$414k/yr
If you are a current Jazz employee please apply via the Internal Career site Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are d…
Skills: Biomarker Strategy, Companion Diagnostics, Oncology, Translational Science, Clinical Development
Charleroi, Pennsylvania, United States · On-site
$87k–$145k/yr
Job Description SummaryAs a Project Manager Specialist, you will be responsible for planning and executing contracts starting from transfer meeting to managing the Quality, Cost, and Delivery of the entire execution proc…
Skills: Project Management, Contract Management, Budget Monitoring, Risk Management, Customer Satisfaction
State College, Pennsylvania, United States · On-site
Automotive Service Technician Bobby Rahal Honda of State College - 2796 W College Ave, State College PA 16801 Schedule: Monday - Friday 7:30am to 5pm Pay: Based on experience WHY YOU'LL LOVE IT HERE Paid time off and six…
Skills: Troubleshooting, Vehicle Repair, Mechanical Systems Repair, Electrical Systems Repair, Automotive Maintenance
Philadelphia, Pennsylvania, United States · On-site
$24/hr–$28/hr
Job TitleHVAC Technician- 2nd Shift Job Description SummaryThe HVAC Technician is responsible for the proper Operation and maintenance of all mechanical systems and equipment. This includes but is not limited to: chiller…
Skills: HVAC Maintenance, BMS/EMS Operation, Troubleshooting, Preventive Maintenance, Mechanical Systems Repair
New Stanton, Pennsylvania, United States · On-site
$59k–$77k/yr
Are you interested in being part of an innovative team that supports Westinghouse's mission to provide clean energy solutions? At Westinghouse, we recognize that our employees are our most valuable asset and we seek to i…
Skills: Machine Tool Set-up, In-process Inspection, Drawing Interpretation, Micrometers, Calipers
Allentown, Pennsylvania, United States · Remote OK
$65k–$70k/yr
Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Cytiva, one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by…
Skills: Troubleshooting, Installation, Preventive Maintenance, Electrical Testing, Mechanical Testing
Philadelphia, Pennsylvania, United States · On-site
Division: Philadelphia Main Project Location(s): Philadelphia, PA 19019 USA Minimum Years Experience: Travel Involved: Job Type: Regular Job Classification: Experienced Education: Job Family: Construction Compensation: S…
Skills: Project Management, Budget Management, Contract Administration, BIM, LEAN
Radnor, Pennsylvania, United States · On-site
$163k–$272k/yr
Overview: The Commercial Credit Manager is responsible for leading a team of credit professionals in evaluating, underwriting, and managing a portfolio of commercial credit relationships. This role involves ensuring adhe…
Skills: Credit Underwriting, Portfolio Management, Financial Statement Analysis, Risk Rating, Cash Flow Analysis
Pittsburgh, Pennsylvania, United States · Remote OK
Sargent Electric is a leading specialty contractor focused on electrical, instrumentation, wireless, utility, and low voltage systems. Founded in Pittsburgh in 1907, we operate from 8 locations across the Midwest, Mid-At…
Skills: Project Management, Electrical Construction, Budgeting, Scheduling, Financial Controls
Norristown, Pennsylvania, United States · On-site
About Us HBK Engineering, LLC is a fully licensed, professional engineering design firm headquartered in Chicago, IL with a staff approaching 700 individuals. HBK provides civil, environmental, structural, electrical, su…
Skills: AutoCAD, MicroStation, GIS Systems, Engineering Design, Project Management
Norristown, Pennsylvania, United States · On-site
About Us HBK Engineering, LLC is a fully licensed, professional engineering design firm headquartered in Chicago, IL with a staff approaching 700 individuals. HBK provides civil, environmental, structural, electrical, su…
Skills: AutoCAD, MicroStation, GIS Systems, Electrical Design, Structural Design
Norristown, Pennsylvania, United States · Hybrid
About Us HBK Engineering, LLC is a fully licensed, professional engineering design firm headquartered in Chicago, IL with a staff approaching 700 individuals. HBK provides civil, environmental, structural, electrical, su…
Skills: AutoCAD, MicroStation, GIS Systems, Civil Engineering Design, Utility Infrastructure Design
Pittsburgh, Pennsylvania, United States · On-site
Job Title: Service Sales – New Business Development Job Location: Pittsburgh PA Operating Company: Energy Transfer Solutions FLSA Status: Exempt Salary Range: Annual draw, plus commission and expenses About: Energy Trans…
Skills: New Business Development, HVAC Service Sales, Account Management, Mechanical System Analysis, Proposal Generation
Harrisburg, Pennsylvania, United States · On-site
Job Title: Service Sales – New Business Development Job Location: Harrisburg PA Operating Company: Energy Transfer Solutions FLSA Status: Exempt Salary Range: Annual draw, plus commission and expenses About: Energy Trans…
Skills: New Business Development, HVAC Service Sales, Account Management, Mechanical Systems Analysis, Proposal Generation
York, Pennsylvania, United States · On-site
Job Title: Service Sales – New Business Development Job Location: York PA Operating Company: Energy Transfer Solutions FLSA Status: Exempt Salary Range: Annual draw, plus commission and expenses About: Energy Transfer So…
Skills: New Business Development, HVAC Service Sales, Account Management, Mechanical Systems Analysis, Proposal Generation
Rahway, New Jersey, United States · Hybrid
$65k–$103k/yr
Job Description Job Description As part of the Cyber Fusion Center (CFC), the Operational Technology (OT) Cyber Security Analyst supports efforts to identify, analyze, and remediate cyber security risks across manufactur…
Skills: Cybersecurity, Operational Technology (OT), Vulnerability Management, Incident Response, Network Security
Indiana, Pennsylvania, United States · On-site
Quintech Electronics & Communications, Inc. is seeking a Production Technician - Floater to join their Production team whose primary duties will include providing support in various departments based on daily production …
Skills: Silkscreen, Mechanical Fabrication, Inventory Management, Shipping and Receiving, Soldering
Tinicum Township, Pennsylvania, United States · On-site
$70k–$80k/yr
Job DetailsJob Location: ARCCA LLC - PENNS PARK, PA 18943Position Type: Full TimeSalary Range: $70,000.00 - $80,000.00Job Shift: DayApplied Technical Services, LLC, is a leading provider of critical testing, inspection, …
Skills: Accident Reconstruction, Workplace Injury Investigation, Safety Compliance Evaluation, Root Cause Analysis, OSHA Regulations
Upper Gwynedd Township, Pennsylvania, United States · On-site
$106k–$167k/yr
Job Description The Nonclinical Drug Safety (NDS) division at our company is seeking a motivated and talented biomedical engineer or integrative systems scientist with experience in signal processing and/or computational…
Skills: Cardiovascular Research, Computational Models, Data Visualization, Machine Learning, Neuroscience
Upper Moreland Township, Pennsylvania, United States · On-site
About this role: As a Biomedical Technician with Fresenius Medical Care, you will maintain and repair medical and water treatment equipment within our kidney care clinics. You will also train and educate colleagues on op…
Skills: Equipment Maintenance, Troubleshooting, Water Treatment Systems, Inventory Management, Technical Documentation
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Leads the enterprise-wide biomarker strategy for oncology, focusing on companion diagnostics and correlative biomarker plans for clinical and nonclinical research. Integrates translational science and regulatory functions to enable precision medicine and data-driven patient stratification.
Requires a doctoral degree (PhD, MD, or MD/PhD) in a relevant scientific field with significant leadership experience in oncology biomarkers. Must have a proven track record in delivering CDx programs and fluency in multi-omic data and molecular assay platforms.
Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information.
The Executive Director, Biomarkers leads enterprise-wide biomarker strategy across the portfolio with an emphasis on oncology, covering companion diagnostics (including global regulatory strategy) and correlative biomarker plans for clinical and nonclinical research. The role integrates translational science, clinical development, biostatistics, and regulatory functions to enable precision medicine, patient stratification, and data‑driven decisions.
Essential Functions/Responsibilities
Own the end-to-end biomarker strategy for oncology programs through design, execution, analyzing, and reporting correlative biomarker studies for clinical trials (Phase 0–3) and nonclinical work, including PK/PD, pharmacogenomic, immunophenotyping, and circulating biomarker readouts.
Lead Companion Diagnostic (CDx) strategy: define intended use, select/manage diagnostic partners/CROs, oversee analytical/clinical validation, and align on regulatory pathways (e.g., PMA/510(k), IVDR).
Embed patient selection/enrichment strategies and biomarker endpoints into protocols and SAPs in partnership with Clinical Development, Biostatistics, and Regulatory.
Author/review biomarker plans, clinical protocols, IB/IND/IMPD sections, CDx submissions, and responses to health authority queries.
Establish fit‑for‑purpose assays (tissue and liquid) and data standards; ensure chain‑of‑custody, quality, and compliance for biospecimens and data.
Build and lead a high‑performing biomarker team; manage budgets, timelines, vendors, and academic collaborations.
Communicate strategy, risks, and recommendations to R&D leadership; represent the company with partners, KOLs, and scientific consortia.
Contribute to Search & Evaluation by assessing biomarker/CDx feasibility and translational rationale for external opportunities.
Oncology experience REQUIRED with deep knowledge of tumor biology, heterogeneity, clinical development, and regulatory considerations.
Non‑oncology biomarker experience PREFERRED (e.g., neuroscience) to cross‑pollinate best practices.
Proven track record delivering biomarker strategies and CDx programs, including analytical/clinical validation and regulatory submissions
Fluency in multi‑omic data (genomics, transcriptomics, proteomics, metabolomics) and molecular assay platforms (IHC/ISH, NGS, PCR, flow cytometry, mass spec, ctDNA).
Experience designing correlative science for both clinical trials and nonclinical studies; ability to translate mechanism of action into measurable pharmacodynamic and patient‑selection hypotheses.
Strong leadership in matrixed environments; ability to influence without authority and manage external partners/CROs.
Excellent oral and written communication; ability to author and review technical and regulatory documents.
Education: Doctoral degree (PhD, MD, or MD/PhD) in molecular biology, genomics, bioinformatics, biomedical engineering, or related field, with significant experience in a drug development setting and significant oncology biomarker leadership.
Preferred: ASCP/MGP or clinical laboratory certifications.
Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.
FOR US BASED CANDIDATES ONLY
Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is:
$276,000.00 - $414,000.00Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.
At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz’s Long Term Equity Incentive Plan.
The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html
Jazz Pharmaceuticals plc (Nasdaq: JAZZ), is a global biopharmaceutical company whose purpose is to innovate to transform the lives of patients and their families. We are focused on developing life-changing medicines for people with rare diseases—often with limited or no options—so they can live their lives more fully. By transforming biopharmaceutical discoveries into novel medicines, we are working to give people around the world the opportunity to redefine what’s possible – to make the “small wins” big again. Founded in 2003, we maintain a highly collaborative culture where employees focus on how they can be successful and accomplish positive results by exemplifying the company’s core values: integrity, collaboration, passion, innovation and the pursuit of excellence. Together, we are experts, analysts, specialists, advocates, scientists and professionals all with diverse backgrounds and perspectives. Working together, we are proud to support patients, innovate and bring new medicines to patients with critical unmet needs in rare disease. Please see our website at www.jazzpharma.com for more information. For information on recruitment, please visit https://careers.jazzpharma.com/. For guidelines on engaging with Jazz on social media, please visit https://bit.ly/2OaMOuq.
Offices: Waterloo Exchange, Waterloo Road, Dublin, 4, IE · 2005 Market St, Philadelphia, Pennsylvania 19103, US · 3170 Porter Dr, Palo Alto, California 94304, US · Oxford Business Park South, Oxford, England OX4 2, GB · 250-887 Great Northern Way, Vancouver, British Columbia V5T 4T5, CA
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