Help Expand What We Can See in Biology At Flagship Pioneering, we build companies around bold scientific ideas. Flagship Labs is our innovation foundry where teams originate, test, and scale breakthrough technologies tha…
Skills: Optical microscopy, Vibrational spectroscopy, Raman microscopy, IR spectroscopy, Instrumentation
Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capita…
What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? COMPANY DESCRIPTION Expediti…
Senior / Principal Scientist - Translational Modeling & Decision Science
Cambridge, Massachusetts, United States · On-site
$179k–$236k/yr
Senior+$9.1B raised
About Pioneering Intelligence Pioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to ac…
Overview Alnylam Pharmaceuticals is seeking a highly technical and strategic Director of Artificial Intelligence to lead the expansion of AI capabilities across the Research organization. This role will establish and lea…
Associate Director, Nonclinical Writing AI Innovation
Cambridge, Massachusetts, United States · Hybrid
$157k–$212k/yr
Senior$4.5B raised
Overview The Associate Director, Nonclinical Writing Innovation, will lead the strategy and adoption of AI-enabled capabilities across nonclinical workflows. This high-visibility role will translate organizational priori…
Skills: AI strategy, Nonclinical writing, Regulatory documentation, Data integrity, AI tool automation
Experimental Systems Intern Location: Cambridge, MA Time commitment: Part-time, approximately 25–30 hours per week; schedule must include multiple in-person laboratory days Duration: 3–6 months, with the potential to tra…
Associate Engineer/ Engineer I, Formulations and Characterization
Cambridge, Massachusetts, United States · On-site
$68k–$101k/yr
Entry level$551M raised
Your Impact at LILA We are seeking a motivated and detail-oriented Associate Engineer / Engineer I to join our high-throughput Research Operations team. In this role, you will focus on hands-on material formulation chara…
Skills: Rheology, Material chemistry, Mechanical testing, Wet-lab, Formulation
Research Scientist I/II, Computational Organic Electronics
Cambridge, Massachusetts, United States · On-site
$176k–$304k/yr
Senior$551M raised
Your Impact at LILA Your role will involve applying computational methods and AI to accelerate the discovery and design of organic electronics materials. You will use first-principles modeling, atomistic simulations, sci…
Your Impact at LILA We are seeking a computational materials scientist to discover and optimize materials for electro-optic and photonic technologies. The role centers on understanding how composition, structure, defects…
Your Impact at LILA Maintenance Engineering Technicians are the backbone of instrument uptime at Lila. You will execute preventive maintenance schedules, perform first-response troubleshooting, maintain calibration and q…
Your Impact at LILA Lila is looking for a hands-on Site Services Coordinator to support day-to-day operations at the 10 Wilson site. This role keeps the workplace running smoothly by managing incoming and outgoing packag…
San Francisco, California, United States · On-site
$204k–$310k/yr
Senior$551M raised
Your Impact at LILA You'll own two connected but distinct areas. First, you'll decide which new scientific domain capabilities the Lila model should gain and how to build them — the right mix of reinforcement-learning en…
Your Impact at LILA You will build the back-end and data foundations of the systems that schedule work across our autonomous labs, model them as digital twins, and turn raw experimental output into trustworthy, queryable…
Staff Research Engineer, Scientific Computing and ML/Physics Infrastructure
London, England, United Kingdom · On-site
$224k–$294k/yr
Senior$551M raised
Your Impact at LILA Lila Sciences is seeking a Research Engineer, Scientific Computing and ML/Physics Infrastructure to help turn promising research tools into robust, scalable systems. This role bridges research and pro…
Scientist II/Senior Scientist, Computational Chemistry, Drug Discovery
London, England, United Kingdom · On-site
$141k–$218k/yr
Senior$551M raised
Your Impact at LILA Lila Sciences is seeking a Scientist, Computational Chemistry, Drug Discovery to help guide, evaluate, and improve AI-driven drug discovery workflows. This person will bring practical computational ch…
Your Impact at LILA We are seeking an Enterprise Account Lead, Materials to define how Fortune 500 energy, manufacturing, and materials companies engage with the world's first platform for scientific superintelligence. Y…
Your Impact at LILA As a Scientist II/Senior Melt Polymer Scientist on the Materials Formulation team at Lila Sciences, you will drive the development and optimization of solid polymers, such as hot melt adhesive systems…
Your Impact at LILA Lila Sciences is looking for an Associate Director / Director, Strategic Finance to join our Strategic Finance team. This role sits at the center of the highest-stakes financial workstreams in the com…
Your Impact at LILA Lila Sciences is seeking a Senior Manager, Capacity Planning to join the team as the company moves from research into commercial-scale operations. You will own the models, processes, and cross-functio…
Skills: Capacity planning, Strategic finance, Revenue operations, Data modeling, Integrated business planning
Design and execute advanced optical and vibrational spectroscopy experiments to characterize biological systems. Manage internal and external experimental portfolios while developing protocols to ensure high-quality, reproducible data.
Requirements
Requires a PhD in physics, biophysics, chemistry, or a related engineering discipline with deep hands-on experience in optical instrumentation. Candidates must demonstrate strong scientific judgment and the ability to independently troubleshoot complex experimental workflows.
Full job description
Help Expand What We Can See in Biology
At Flagship Pioneering, we build companies around bold scientific ideas. Flagship Labs is our innovation foundry where teams originate, test, and scale breakthrough technologies that can become new bioplatforms.
At Flagship Labs 120, we’re assembling a multidisciplinary team to invent, build, and rapidly test innovative technologies for observing biological systems. We are looking for a scientist with deep hands-on experience in optics and vibrational spectroscopy to join the team and help turn promising experimental opportunities into practical capabilities for the platform.
This is a zero-to-one role for an engineering-minded scientist who enjoys turning new ideas into practical experiments. We are looking for someone who favors fast, practical, hands-on solutions and will help shape the scientific direction and experimental foundation of a new venture through work across instrumentation, biology, and external collaborations.
Responsibilities
Design and execute experiments using advanced optical and vibrational spectroscopy measurement techniques to characterize biological systems.
Own a portfolio of internal and external experiments, coordinating work across CROs, university core facilities, academic collaborators, and internal teams.
Develop, refine, and document experimental workflows, protocols, and SOPs to improve measurement quality, reproducibility, and operational efficiency.
Troubleshoot instrumentation, identify sources of experimental variability, and improve data quality and reproducibility.
Stay current across relevant fields to identify promising new experiments and applications.
Contribute to the scientific strategy and technical roadmap of a founding-stage venture.
Qualifications
Required
PhD (or equivalent experience) in physics, biophysics, chemistry, engineering, bioengineering, or a related discipline.
Deep hands-on experience developing and applying optical microscopy and vibrational spectroscopy techniques such as Raman microscopy, IR spectroscopy, or related methods.
Strong experimental background and demonstrated ability to independently execute and troubleshoot complex experiments.
Solid understanding of the physics and engineering of optical instrumentation.
Strong scientific judgment and the ability to distinguish meaningful biological signals from technical artifacts.
Preferred
Experience developing or optimizing advanced Raman spectroscopy (e.g. CARS, SRS) or IR spectroscopy (e.g. photothermal IR), or related techniques.
Experience working with biological samples such as cells or tissue. Familiarity with cell culture or live cell assays is a plus.
Familiarity with molecular or cell biology sufficient to understand literature and adopt new experimental protocols.
Programming or scripting experience (Python, MATLAB, or similar) for instrument automation and experimental data analysis.
Experience working with external collaborators, university core facilities, or CROs.
Previous experience in startup, translational, or highly interdisciplinary research environments.
Why Join FL120?
This is an opportunity to join a founding scientific team exploring an entirely new experimental platform. Success will require curiosity, creativity, and a willingness to cross traditional disciplinary boundaries. You'll play an important role in exploring new ideas, establishing new experimental capabilities, and helping shape the scientific direction of a company from its earliest days.
As the company grows, this role will help shape the evolution of our platform and broader technical strategy.
We welcome applications from experienced scientists as well as exceptional postdoctoral researchers or advanced graduate students interested in either full-time or part-time opportunities.
ABOUT FLAGSHIP PIONEERING
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
The salary range for this role is $100,000 - $180,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL120 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL120's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [email protected].
We are a biotechnology company that invents and builds platform companies that change the world.
Industry
Biotechnology Research
Company size
501-1,000 employees
Founded
2000
Headquarters
Cambridge, MA
LinkedIn followers
160,510
Total funding
$9.1B
Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple transformative human health and sustainability products. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures.
The current Flagship ecosystem comprises over 40 companies, including Denali Therapeutics, Foghorn Therapeutics, Generate:Biomedicines, Inari, Indigo Agriculture, and Tessera Therapeutics.
Offices: 55 Cambridge Parkway, Suite 800E, Cambridge, MA 02142, US
life sciencesbiotechtherapeuticsdiagnosticssustainabilityclimate changeartificial intelligencemachine learningagtechmedicines
Based on 657 listings with disclosed salaries, most technology jobs in Cambridge, MA pay between $88k–$245k per year. Individual offers vary with seniority, company size, and specialization.
How many Technology jobs are open in Cambridge, MA right now?
There are currently 822 open technology positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Technology roles in Cambridge, MA?
Companies currently hiring include Draper, Akamai Technologies, Lila Sciences, Harvard Division of Medical Sciences, Flagship Pioneering, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Technology jobs in Cambridge, MA?
Yes — 362 of the 822 open technology positions offer remote or hybrid work (91 remote, 271 hybrid).
How do I apply for Technology jobs in Cambridge, MA?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.