Relay TherapeuticsCambridge, Massachusetts, United States · On-site
The Opportunity: We are seeking an exceptional scientific leader to oversee our integrated Medicinal Chemistry, Computational Chemistry, Cheminformatics, and Drug Metabolism & Pharmacokinetics (DMPK) organizations. This …
Skills: Medicinal Chemistry, Computational Chemistry, Cheminformatics, DMPK, Small Molecule Drug Discovery
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Cambridge, Massachusetts, United States · On-site
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Relay Therapeutics
Cambridge, Massachusetts, United States • On-site
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The VP will lead and integrate the Medicinal Chemistry, Computational Chemistry, Cheminformatics, and DMPK organizations to drive the discovery of small molecule therapeutics. They will define scientific strategies and foster a collaborative environment to advance programs from target validation through development candidate nomination.
Candidates must hold a Ph.D. in Organic or Computational Chemistry with over 15 years of leadership experience in drug discovery. A proven track record of advancing small molecule programs and expertise in modern computational approaches like AI/ML is required.
The Opportunity:
We are seeking an exceptional scientific leader to oversee our integrated Medicinal Chemistry, Computational Chemistry, Cheminformatics, and Drug Metabolism & Pharmacokinetics (DMPK) organizations. This individual will be responsible for driving the discovery and optimization of transformative small molecule therapeutics by building a highly collaborative, data-driven discovery engine that combines deep scientific expertise with modern computational approaches.
The successful candidate will be a recognized leader in small molecule drug discovery with a proven track record of advancing programs from hit identification through IND filing. They will be a key member of research leadership, fostering an environment where all disciplines work as a unified team to rapidly test hypotheses, learn from experimental data, and deliver differentiated medicines.
This role is ideal for a leader who is energized by solving complex scientific problems, embracing emerging technologies, and building high-performing scientific organizations within a fast-paced biotechnology environment.
We believe breakthrough medicines emerge from the seamless integration of human creativity, rigorous experimentation, and advanced computational science. Our discovery strategy combines hypothesis-driven biology, medicinal chemistry, computational chemistry, structural biology, and DMPK to iteratively design, test, and refine molecules based on quantitative experimental evidence. By coupling deep scientific expertise with state-of-the-art computational technologies, we aim to accelerate learning, improve decision quality, and deliver differentiated therapies for patients with serious diseases.
Your Role:
Scientific Leadership
Organizational Leadership
Innovation
Your Background:
Estimated Salary Range: [$230,000 - $328,000]
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#JO1
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
Integrating leading-edge computational and experimental science to transform human health.
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, our approach combines unprecedented computational power with leading-edge experimental approaches across the fields of structural biology, biophysics, chemistry and biology. By applying these insights, we believe we have a differentiated approach to drug protein targets based on their motion, enabling us to select and advance unique product candidates that can be developed into novel therapies for patients. Located in Cambridge, Massachusetts, our world-class team is equal parts bright and bold, with a shared passion for working in intellectually stimulating environments. If you're creative, collaborative and passionate about making a difference in the lives of patients, join us!
Offices: 60 Hampshire St, Cambridge, Massachusetts 02139, US
Based on 657 listings with disclosed salaries, most technology jobs in Cambridge, MA pay between $88k–$245k per year. Individual offers vary with seniority, company size, and specialization.
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