Durham, North Carolina, United States · On-site
Opportunity for Secondment to AskBio We’re pleased to share an exciting secondment opportunity at AskBio. This role is available for a time period to be determined by leadership at both Bayer and AskBio. While most assig…
Skills: DNA Design, rAAV Manufacturing, Molecular Biology, Bacterial Cell Culture, DNA Purification
Durham, North Carolina, United States · On-site
AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfoli…
Skills: DNA Design, rAAV Manufacturing, Molecular Biology, Bacterial Cell Culture, DNA Purification
Durham, North Carolina, United States · On-site
$25/hr–$50/hr
Company Description RRD is a leading global provider of marketing, packaging, print, and supply chain solutions that elevate engagement across the complete customer journey. The company offers the industry’s most trusted…
Skills: Gravure press operation, Multi-color offset press operation, Press setup, Color correction, Mechanical maintenance
Allegiance Industries, Inc.Durham, North Carolina, United States · On-site
$14/hr
Job DetailsJob Location: 019132 - Durham, NC 27712Salary Range: $14.00 - $14.00 HourlyJob Shift: 1st Currently Hiring: Part Time 1st Shift General Cleaner in Durham, NC. Shift: Monday - Thursday 7AM - 2PM and occasional …
Skills: Sweeping, Vacuuming, Mopping, Trash Removal, Restroom Sanitation
Durham, North Carolina, United States · On-site
As an Applications Engineer for Advanced Packaging, you will provide pre- and post-sales technical support to customers integrating Wolfspeed SiC substrates into 2.5D and 3D packaging architectures for high-performance c…
Skills: Advanced Packaging, SiC Substrates, Thermal Simulation, 2.5D/3D Integration, Process Integration
Durham, North Carolina, United States · Hybrid
JOB SUMMARY: This position is for an attorney to manage legal issues and coordinate compliance in unregulated business subsidiaries including support of project development and construction, day to day management of lega…
Skills: Contract Negotiation, Commercial Drafting, Legal Compliance, Risk Mitigation, Project Development
Durham, North Carolina, United States · Hybrid
ABOUT LCI The mission of LCI is to provide meaningful employment for the blind and visually impaired. We accomplish this in four ways: EMPLOY: We are one of the largest employers of people who are blind, creating meaning…
Skills: Enterprise Risk Management, Occupational Health and Safety, OSHA Compliance, DOT/FMCSA Compliance, Environmental Compliance
Durham, North Carolina, United States · On-site
Minimum Qualifications: (Education, Experience, Knowledge, and Skills): High School Diploma or equivalent required. Associate’s degree preferred. 2+ years of experience in a manufacturing environment, preferably in…
Skills: Production Supervision, ERP Systems, Lean Manufacturing, Technical Drawing Interpretation, Performance Reporting
Durham, North Carolina, United States · On-site
Kymera International - Specialty Materials that Shape the Future Warehouse Assistant - 2nd Shift The Warehouse Assistant will prepare orders for shipment by reading a pick list, gathering orders, adding strapping and str…
Skills: Warehouse operations, Forklift operation, Inventory management, Order picking, Shipping and receiving
Wilmington, Massachusetts, United States · On-site
About Analog Devices Analog Devices, Inc. (NASDAQ: ADI) is a global semiconductor leader that bridges the physical and digital worlds to enable breakthroughs at the Intelligent Edge. ADI combines analog, digital, AI, and…
Skills: Power Electronics, System Architecture, DC/DC Converters, Wide-Bandgap Devices, GaN
Wilmington, Massachusetts, United States · On-site
About Analog Devices Analog Devices, Inc. (NASDAQ: ADI) is a global semiconductor leader that bridges the physical and digital worlds to enable breakthroughs at the Intelligent Edge. ADI combines analog, digital, AI, and…
Skills: Power Electronics, System Architecture, PCB Layout, Cadence Allegro, Altium Designer
Durham, North Carolina, United States · On-site
JOB DESCRIPTION Solution Prep Manufacturing Supervisor 12 hour Night Shift 2*2*3 Schedule The Manufacturing Supervisor, Solution Prep leads a team of manufacturing associates to perform both upstream and downstream prepa…
Skills: cGMP Compliance, Bioprocessing, Team Leadership, Solution Preparation, CAPA
Durham, North Carolina, United States · On-site
Job Description Day Shift / 7AM -7PM / 2-2-3 schedule The Manufacturing Associate I/II will perform Upstream or Downstream production activities for early and late-phase Cell Culture programs in a GMP environment. Respon…
Skills: Aseptic Processing, GMP/GDP/GLP Standards, Cell Culture, Bioreactor Operations, Chromatography
Locus Biosciences, Inc.Durham, North Carolina, United States · On-site
Locus Biosciences is seeking a highly motivated and entrepreneurial applicant to join our company in a full-time, entry-level position that will rotate between our Chemistry, Manufacturing and Controls (CMC) and Research…
Skills: Molecular Biology, Microbiology, Bioprocess Development, Aseptic Technique, NGS Library Preparation
Durham, North Carolina, United States · On-site
Position Summary: Click image below to see the day in the life of our Storeroom Attendant! Join our exciting & dedicated team at Vallen as a Storeroom Crib Attendant. In this position, you will be working at a customer's…
Skills: Inventory Management, Receiving, Cycle Counting, Forklift Operation, Data Entry
Durham, North Carolina, United States · On-site
$70k–$110k/yr
Description Verista’s 500 experts team up with the world’s most recognizable brands in the life science industry to solve their business needs. The nature of our business is to empower growth and innovation within the sc…
Skills: Commissioning, Qualification, Validation, Risk Assessment, GMP
Durham, North Carolina, United States · On-site
$28/hr–$42/hr
Maintenance Tech 3 - Night Shift Reports To: Supervisor, Maintenance Position SummaryGeneric Summary Manages repair and maintenance of manufacturing equipment and utilities including: Installing, repairing, and maintaini…
Skills: Preventive Maintenance, Corrective Maintenance, Root-Cause Analysis, PLC Troubleshooting, Ladder Logic
Durham, North Carolina, United States · Hybrid
$75k–$85k/yr
Supports product testing and certification projects by conducting technical evaluations, coordinating lab testing, and ensuring compliance with UL standards. Works directly with customers, manages project timelines, prep…
Skills: Product Testing, Certification, Technical Evaluation, Lab Testing Coordination, UL Standards Compliance
GRAILDurham, North Carolina, United States · On-site
$69k–$93k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Lean Methodologies, Six Sigma, Kaizen, Statistical Process Control, Data Analysis
GRAILDurham, North Carolina, United States · On-site
$94k–$125k/yr
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can tran…
Skills: Lean Methodologies, Six Sigma, Kaizen, Statistical Process Control, Data Visualization
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Lead initiatives to optimize DNA manufacturability, quality, and scalable production for rAAV manufacturing. This includes the rational design of DNA constructs, managing CMDO collaborations, and authoring technical regulatory documentation.
Requires a PhD with 5+ years of experience or an MS with 10+ years of experience in Molecular Biology, Genetics, or Virology. Expertise in viral gene therapy and recombinant adeno-associated virus systems is essential.
We’re pleased to share an exciting secondment opportunity at AskBio.
This role is available for a time period to be determined by leadership at both Bayer and AskBio. While most assignments range from one to two years, the exact duration will be based on business needs and mutual agreement.
This secondment offers a unique chance to broaden your experience, expand your knowledge, and contribute meaningfully to AskBio’s mission: to advance gene therapy and change the lives of patients around the world.
If you’re interested in exploring this opportunity, we encourage you to:
Speak with your direct manager to discuss your interest and alignment with your development goals.
Apply directly using the link provided in the posting.
We look forward to seeing how our colleagues continue to grow and make an impact across the Bayer-AskBio partnership.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.
Advance innovative science by pushing boundaries.
Bring transformative therapeutics to patients in need.
Provide an environment for employees to reach their fullest potential.
Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.
This strategic role leads independent initiatives to optimize DNA manufacturability, quality, and scalable production. The successful candidate will be accountable for the rational design and technical review of DNA constructs that serve as critical starting material for rAAV manufacturing. This role drives process understanding by linking DNA design to process performance and vector quality while generating summary technical documentation and fostering a collaborative culture of scientific excellence.
This position is based on-site in Research Triangle Park (RTP), North Carolina, and reports to the Process Development Associate Director/Director.
Independently design and execute project initiatives to improve DNA manufacturability and quality with good judgement against defined timelines
Rationally design and test DNA constructs to increase DNA and rAAV manufacturing productivity and/or improved DNA and vector quality
Provide subject matter expertise on development of new and/or improved methodologies for DNA production that is fit for purpose (scale, yield etc)
Lead AskBio CMDO collaborations to improve DNA manufacturing and transfer of relevant processes
Serve as a technical consultant on DNA starting materials used for Chemistry, Manufacturing and Control (CMC) activities and regulatory strategis, when applicable
Lead investigations and troubleshooting of DNA purification and analytical characterization as needed
Represent the DNA Development function in project teams and present data at internal and external forums
Author technical and development documents, including relevant regulatory submission sections
Excellent team player who develops and encourages a team environment within the company’s mission and values
Mentors and develops team members by establishing a collaborative and growth minded culture that encourages personal and professional development
Perform hands-on experiments, when necessary, while maintaining and promoting a clean, efficient, and safe laboratory environment
PhD (Molecular Biology, Genetics, Virology or equivalent) with 5+ years of relevant work experience including post-doc experience; or MS (Molecular Biology, Genetics, Virology or equivalent) with 10+ years of relevant work experience
Expertise in viral gene therapy, including recombinant adeno-associated virus systems
Strong, comprehensive understanding of the molecular attributes that influence both DNA replication in bacteria and rAAV production in mammalian culture
Demonstrates self-motivation, strong orginzational acumen, and independent strategic thinking with the versatility to perform effectively in both autonomous and collaborative settings
Excellent written and verbal communication, work planning, data analysis and record keeping skills
Good working knowledge of Microsoft Office suite (Word, Outlook, Excel) and SnapGene
In-depth knowledge of bacterial cell culture (E. coli preferred), establishing bacterial glycerol stocks, DNA purification by commercially relevant methods, and molecular biology techniques such as cloning, PCR, DNA quantification, restriction enzyme digest and Sanger and/or NextGen Sequencing
Demonstrated technical proficiency with fermenters/bioreactors, AKTA liquid chromatography systems, and tangential flow filtration
Competnecy with electronic laboratory notebooks
Applied understanding of rAAV manufacturing
AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at talent@askbio.com.
AskBio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular and metabolic disease indications with a clinical-stage pipeline that includes therapeutics for congestive heart failure, limb-girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease. AskBio’s gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive capsid and promoter library. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing. Learn more at askbio.com. Vision - Pioneering science to create transformative molecular medicines. Mission - Lead innovative science and drive clinical outcomes to transform people's lives. Values: • Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need. • Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view. • Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers. • Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action. • Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.
Offices: 20 TW Alexander Dr, Suite 110, Research Triangle Park, North Carolina 27709, US · 2929 Arch St, Philadelphia, Pennsylvania 19104, US · Roslin Innovation Centre Easter Bush Campus, Edinburgh, Scotland EH25 9RG, GB · 47, Boulevard de l'hôpital, Paris, Île-de-France 75013, FR · Am Taubenfeld 21/1, Heidelberg, Germany 69123 , DE
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