San Francisco, California, United States · Remote OK
AgileEngine is an Inc. 5000 company that creates award-winning software for Fortune 500 brands and trailblazing startups across 17+ industries. We rank among the leaders in areas like application development and AI/ML, a…
Skills: Application Security, DevSecOps, Python, Java, SAST
San Francisco, California, United States · On-site
The Models, Quantum, & Silicon (MQS) Center for Quantum Computing (CQC) is a multi-disciplinary team of scientists, engineers, and technicians, on a mission to develop a fault-tolerant quantum computer. We are looking to…
Skills: HPC Infrastructure, AWS, Infrastructure-as-Code, CI/CD Pipelines, Python
San Francisco, California, United States · Hybrid
$257k–$445k/yr
About the Team The Strategic Initiatives & Operations team is in need of a Technical Program Manager (TPM) to streamline our processes, including full safety governance and integration of various safety research and miti…
Skills: Technical Program Management, Risk Assessment, Safety Governance, Stakeholder Management, Process Design
San Francisco, California, United States · On-site
$185k–$210k/yr
Job Description: Purpose: Acts as a senior technical team member of data and digital solutions engineering team including custom applications, vendor applications, software-as-a-service, and other services related to dat…
Skills: Data Modeling, Data Integration, RDBMS, Data Lake House, ETL/ELT
San Francisco, California, United States · On-site
$130k–$150k/yr
Who We Are Notion is the collaborative AI workspace where teams and agents think together. We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, an…
Skills: Data Structures, Algorithms, Distributed Systems, Problem Solving, Proactive Communication
San Francisco, California, United States · Hybrid
$130k–$150k/yr
Who We Are Notion is the collaborative AI workspace where teams and agents think together. We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, an…
Skills: Data Structures, Algorithms, Distributed Systems, LLMs, Embeddings
San Francisco, California, United States · On-site
$130k–$190k/yr
About the Role YWe are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dr…
Skills: Hardware Design, Automated Peptide Synthesis, Fluidic Architecture, Control Systems, Electromechanical Prototyping
San Francisco, California, United States · On-site
$120k–$165k/yr
About the Role You’ll work closely with the founders and a small team from MIT, Harvard Medical School, Baker Lab, and Radical Numerics. We are looking for speed and rigor, coupled with excitement, drive and a strong wor…
Skills: Cell-based Assays, GPCR Pharmacology, Cell Culture, Fluorescence Imaging, Luminescence Readouts
San Francisco, California, United States · On-site
$90k–$140k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: Peptide Synthesis, Solid-Phase Peptide Synthesis, Analytical HPLC, Prep HPLC, LC-MS
San Francisco, California, United States · On-site
$165k–$220k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: Peptide Synthesis, Organic Chemistry, Medicinal Chemistry, HPLC, Prep HPLC
San Francisco, California, United States · On-site
$90k–$140k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: Organic Chemistry, Small-molecule Synthesis, Peptide Synthesis, Route Planning, Analytical HPLC
San Francisco, California, United States · On-site
$90k–$220k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: Medicinal Chemistry, Synthetic Organic Chemistry, Peptide Synthesis, Solid-phase Synthesis, Solution-phase Synthesis
San Francisco, California, United States · On-site
$200k–$260k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: Peptide Chemistry, Solid-phase Peptide Synthesis, Solution-phase Synthesis, Analytical HPLC, Prep HPLC
San Francisco, California, United States · On-site
$130k–$210k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: Hardware Engineering, Electromechanical Systems, Control Systems, Microfluidics, Medical Device Design
San Francisco, California, United States · On-site
$135k–$180k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: RNA Therapeutics, ASO Design, siRNA, Nucleic Acid Chemistry, Pharmacology
San Francisco, California, United States · On-site
$150k–$300k/yr
About the Role We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, dri…
Skills: Machine Learning, Biomolecular Modeling, Protein Modeling, Drug Design, Active Learning
San Francisco, California, United States · Hybrid
$175k–$225k/yr
About Sprinter Health: At Sprinter Health, our mission is reimagining how people access care by bringing it directly to their homes. Nearly 30% of patients in the U.S. skip preventive or chronic care simply because they …
Skills: JavaScript, TypeScript, Python, Backend Engineering, Full-stack Engineering
San Francisco, California, United States · On-site
$250k–$315k/yr
Why Mintlify? We're on a mission to empower builders. Massive reach: Our docs platform serves 100 million+ developers every year and powers documentation for 20,000+ companies, including Anthropic, Microsoft, PayPal, Spo…
Skills: Backend Engineering, Customer-facing Communication, Cloud Infrastructure, Networking, SSO
San Francisco, California, United States · On-site
About Primer Primer is a growing network of K–8 schools restoring the timeless foundations of American education. Inspired by the original teaching primers that shaped a nation of readers, thinkers, and builders, our sch…
Skills: Architectural Project Management, Interior Design, Code Analysis, Zoning Review, Permitting
AffinitySan Francisco, California, United States · Hybrid
$160k–$235k/yr
Affinity stitches together billions of data points from massive datasets to create a powerful, accurate representation of the world's professional relationship graph. Based on this data, we offer our users the insights a…
Skills: Machine Learning, Ranking Systems, Recommendation Systems, Python, PyTorch
San Francisco, California, United States • Remote OK
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Architect and build automated security layers within the SDLC, including AI-enabled secure code scanning and CI/CD tooling integration. Provide code-level remediation guidance to development teams and develop automated security runbooks.
Requires 6+ years of software engineering experience with a strong focus on AppSec and DevSecOps. Proficiency in Python and Java is essential, along with deep expertise in deploying and tuning SAST, DAST, and SCA tools.
We turn ideas into software that people love. Solutions that drive business growth. Dedicated engineering & design teams
AgileEngine is a digital consultancy offering top-1% tech talent across 15+ countries. We’ve helped 300+ clients in 17+ industries — from VC-backed startups to Fortune 500 brands — build software that solves real-world problems and drives measurable impact. Our clients achieve up to 3x higher ROI and 3x faster time-to-hire, with some partnerships spanning 10+ years. Work with AgileEngine your way. Our flexible engagement models include staff augmentation and end-to-end product delivery, depending on your needs — ensuring faster scaling, seamless collaboration, and AI-enhanced productivity. What we offer: • Custom software development – scalable web, mobile, and backend solutions. • AI & data solutions – GenAI, ML, and analytics for faster, smarter decisions. • Design solutions – UX/UI consultancy and product design that wows users. • Quality solutions – QA automation and testing for flawless delivery. Our impact speaks for itself. AgileEngine has been listed on the Inc. 5000 for nine consecutive years, named among the Top 100 Software Development Companies of 2025 by Techreviewer, and recognized by Clutch as a Top Machine Learning Company. Ready to build something exceptional? Schedule a free discovery call with our team!
Offices: Boca Raton, Florida, US · Greater São Paulo, BR · Ciudad de México, 00-16, MX · Kyiv, 01000, UA · Kharkiv, 61000, UA
Based on 2822 listings with disclosed salaries, most engineering jobs in San Francisco, CA pay between $130k–$284k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 3,686 open engineering positions in San Francisco, CA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include OpenAI, Anthropic, San Francisco Department of Public Health, Crusoe, Pinterest, among others. Browse the listings above to see every active employer.
Yes — 1857 of the 3686 open engineering positions offer remote or hybrid work (372 remote, 1485 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
