Bedford, Massachusetts, United States · Remote OK
$225k–$250k/yr
About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augment…
Skills: CMC Leadership, Process Development, Analytical Methods, Tech Transfer, CMC Regulatory Strategy
Woburn, Massachusetts, United States · On-site
$23/hr–$37/hr
Basic Function of the Job: Support wafer and chip production in all areas of the Semiconductor Fab, focusing on chip pick and place. Additional responsibilities include: prepare materials for shipment to customers, assis…
Skills: Chip Pick and Place, Die Handling, Microscope Operation, Hand-Eye Coordination, MS Word
Waltham, Massachusetts, United States · On-site
$97k–$184k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: Experimental Design, Method Development, Biologics Manufacturing, Technology Transfer, Process Validation
Wellesley, Massachusetts, United States · Remote OK
$85k–$110k/yr
About Redpoint Global Redpoint Global helps the world’s most ambitious brands deliver personalized, real-time customer experiences across every channel. We lead by a shared set of values: market-leading innovation, flawl…
Skills: ETL, SQL, Data Hygiene, Identity Resolution, Relational Database Design
Mountain View, California, United States · Hybrid
$149k–$217k/yr
Lightmatter is leading the revolution in AI data center infrastructure, enabling the next giant leaps in human progress. The company invented the world’s first 3D-stacked photonics engine, Passage™, capable of connecting…
Skills: Analog Circuit Design, Mixed-Signal Architecture, Optical Transceivers, Cadence Virtuoso, Cadence Spectre
Boston, Massachusetts, United States · On-site
New Flyer is North America's heavy-duty transit bus leader and offers the most advanced product line under the Xcelsior® and Xcelsior CHARGE® brands. It also offers infrastructure development through NFI Infrastructure S…
Skills: Electrical Troubleshooting, Mechanical Troubleshooting, J1939 Communications, CAN Bus Analysis, Ladder Logic
Boston, Massachusetts, United States · Hybrid
$150k–$200k/yr
Break away from your silo to grow your career while working on high profile Mission Critical Data Centers. Join us to do the best work of your career on our growing team and make a profound environmental impact as a Seni…
Skills: Project Management, MEP/FP, A/E Consulting, Budget Management, Schedule Management
Boston, Massachusetts, United States · Hybrid
About Pelico Every 16 minutes, something disrupts how a factory runs. Supply chains don't fail from bad decisions, they fail from late ones. Pelico's platform already helps leading manufacturers anticipate and respond to…
Skills: Multi-agent Systems, Orchestration Runtimes, AI Observability, Production Coding, Platform Engineering
Boston, Massachusetts, United States · Remote OK
Founded in 2001 and headquartered in Ottawa, Fidus Systems specializes in electronic system design and development, with teams in Ottawa, Waterloo, and San Jose focusing on FPGA design, embedded software, ASIC RTL design…
Skills: Business Development, Hardware Design Cycles, Sales Prospecting, Engineering Services Sales, Account Management
Westborough, Massachusetts, United States · On-site
$28/hr–$31/hr
Benefits: Health insurance Paid time off 401(k) 401(k) matching Competitive salary Job Summary Columbia Tech provides Time to Market Services at WARP SPEED™,including product development, manufacturing, global fulfillmen…
Skills: Electrical Manufacturing, Mechanical Manufacturing, Supervisory Leadership, Blueprint Reading, Microsoft Office
Milford, Massachusetts, United States · Remote OK
$60k–$80k/yr
Overview Tri-Point (SITECH Northeast affiliate/subsidiary) is seeking a 3D Civil Modeler/Designer to join our dedicated team. We are looking for someone with a passion for the construction industry, and knowledge of the …
Skills: 3D Surface Modeling, GPS Machine Control, Construction Layout, Trimble Business Center, Carlson Civil
Burnaby, British Columbia, Canada · On-site
$85k–$115k/yr
The Marketing Communications Specialist develops and manages content that communicates RDH’s expertise, people, projects, and thought leadership across digital and print channels. As a member of the Corporate Marke…
Skills: Content Development, Digital Marketing, WordPress, Adobe InDesign, Adobe Photoshop
Burlington, Massachusetts, United States · On-site
$65k–$75k/yr
Company Description Brainlab revolutionized digital medical technology with the introduction of software for radiosurgery and surgical navigation. Today, Brainlab is an industry leader in digital surgery, radiotherapy an…
Skills: Clinical Consulting, Problem Solving, Technical Support, Clinical Case Coverage, Customer Training
Mansfield, Massachusetts, United States · On-site
$90k–$115k/yr
If you are an Engineering Professional looking for an opportunity to gain experience, Emerson has an exciting opportunity for you! Based in our Mansfield, MA location, you will be part of the team that produces pressure …
Skills: CAD, Mechanical Design, Stress Analysis, Product Sizing, Product Selection
Franklin, Massachusetts, United States · On-site
$17/hr–$19/hr
*This position is eligible for a 22.5% shift differential for employees working on third shift* Build Your Career as an EDM Operator in a High-Precision Manufacturing Environment! Join a team that values quality, teamwor…
Skills: EDM Operation, Blueprint Reading, Precision Measurement, Micrometer, Caliper
Boston, Massachusetts, United States · Hybrid
$55/hr–$75/hr
The Role This is a 6-month contract role, with a potential to convert to full-time on the Platform Engineering team, working closely with global development, operations, and delivery teams. Platform Engineering owns the …
Skills: AWS, Kubernetes, EKS, Terraform, Python
Boston, Massachusetts, United States · Hybrid
$55/hr–$75/hr
Meet the future Akoya is an API-based network backed by major financial institutions that creates a safer and more transparent way for people to safely send their personal financial data to third-party financial apps. If…
Skills: AWS, Kubernetes, EKS, CI/CD, Python
Bedford, Massachusetts, United States · On-site
$140k–$150k/yr
Applied Research Solutions has an exciting new opportunity for a Senior Test Engineer to provide support to the Air Force Life Cycle Management Center Electronic Systems PEO (AFLCMC/ES). The Electronic Systems System (ES…
Skills: Test And Evaluation (T&E), Agile Software Development, CI/CD Pipelines, DevSecOps, DevOps
Boulder, Colorado, United States · Remote OK
$175k–$200k/yr
Join the Market Leader in Electric Power Data and Analytics Solutions The electrical grid is the largest and most complicated machine ever built. Yes Energy’s industry-leading electric power trading analytics software pr…
Skills: Engineering Leadership, Agile Methodologies, Kanban, Software Architecture, DevOps
Dartmouth, Massachusetts, United States · On-site
Company Description Cornerstone Building Brands is the largest manufacturer of exterior building products in North America. Headquartered in Cary, North Carolina, the organization serves residential and commercial custom…
Skills: Operations Leadership, Lean Manufacturing, Cross Functional Leadership, COGS Reduction, TQM
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Lead cross-functional teams accountable for Chemistry, Manufacturing, and Controls (CMC) product lifecycle management from early development through commercial launch. Serve as the primary CMC voice in program governance, overseeing supply strategies, regulatory filings, and drug-device compatibility.
Requires a Bachelor's degree in a scientific field (advanced degree preferred) and 10+ years of industry experience in CMC development. Must have significant experience with drug-device combination products and a proven track record of leading late-stage development through commercial launch.
Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/
The Stoke Therapeutics team is seeking an experienced and driven Director, CMC Lead to lead cross-functional teams that are accountable for chemistry, manufacturing, and controls (CMC) product lifecycle management. This individual will serve as the single point of accountability for all CMC activities, from early development through regulatory approval and commercial lifecycle management. This individual will play a central role in shaping the technical and operational direction of their assigned programs. The CMC Lead role is a highly visible matrix team leader that provides strategic and technical leadership within CMC, while representing CMC on cross-functional Program Teams.
The ideal candidate will possess strong knowledge of CMC leadership with deep understanding of process development, analytical methods, tech transfer, manufacturing, CMC regulatory strategy and health authority interactions. Additionally, this individual should possess strong interpersonal communication skills, high emotional intelligence, and be fluent in the art of negotiation.
This position will report into the Vice President, Commercial Manufacturing.
Stoke is located in Bedford, MA, and will be moving to a new location in Waltham, MA by the end of 2026. This position is eligible for either remote or hybrid work arrangements.
This position will require approximately 10-20% travel.
At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program.
The anticipated salary range for this role is $225,000 - $250,000 The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation.
Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP).
At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.
Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do.
https://www.stoketherapeutics.com/careers/
For more information, visit https://www.stoketherapeutics.com/.
All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status.
Stoke participates in E-Verify.
Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/.
Offices: 45 Wiggins Ave, Bedford, Massachusetts 01730, US
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