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The Scientist will execute and optimize sample preparation workflows for a single-molecule protein sequencing platform and complementary multi-omic technologies. They will also analyze experimental data to support performance benchmarking and collaborate with multidisciplinary teams to advance research objectives.
Candidates must hold a degree in biochemistry, chemical biology, molecular biology, or a related field with relevant hands-on experience in sample preparation. Proficiency in NGS library preparation, protein/nucleic acid extraction, and analytical troubleshooting is required.
At Glyphic Biotechnologies, we plan to create the protein revolution for which scientists and researchers have been waiting. We are developing a massively parallel, single-molecule proteome sequencing platform that will transform life science discovery and usher in a new era of insights into human biology and disease. To date, we have raised >$80M from venture partners and non-dilutive grant funding to achieve our vision of next generation proteome sequencing.
We are seeking a technically driven, detail-oriented, and collaborative Scientist to apply and optimize sample preparation workflows across Glyphic’s single-molecule protein sequencing platform (ProSE), as well as complementary DNA sequencing, RNA sequencing, and mass spectrometry-based proteomics workflows. Reporting to the Director of Assay Integration, you will execute and refine established sample preparation protocols across a broad range of biological inputs and generate high-quality data that supports ProSE performance benchmarking and Glyphic’s broader multi-omic strategy, combining ProSE, RNA-seq, DNA-seq, Ribo-seq, and mass spectrometry to identify neoantigens, biomarkers, and drug targets
The ideal candidate is comfortable executing and troubleshooting multi-step protocols across both nucleic acid- and protein-based workflows, rapidly adapting established methods to new sample types, and communicating results clearly across multidisciplinary teams. A track record of hands-on sample prep execution across proteomics and NGS platforms, and comfort operating in high-throughput environments, will be key to making an immediate impact.
This is a full-time, exempt, in-person position with work conducted at our Berkeley, CA location.
Sample Preparation & Assay Execution
Assay Optimization & Data Analysis
Required:
Nice to have:
We’re looking for a teammate that:
Work environment:
Professional growth:
Compensation
Estimated Base Salary $90,200 - $129,500
This is the pay range for this position that we reasonably expect to pay. Individual compensation is based on various factors including, experience, education, skillset, and geographic location. This range is for the SF Bay Area, California location and may be adjusted to the labor market in other geographic areas.
We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Individuals seeking employment at Glyphic Biotechnologies are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation.
Next Generation Proteome Sequencing.
We sequence proteins. Glyphic Biotechnologies is decoding the human proteome through full coverage, de novo protein sequencing at single molecule resolution to enable the development of novel therapeutics and diagnostics and, ultimately, a deeper understanding of life itself.
Offices: Berkeley, CA, US
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