Business System Engineer – Enterprise Applications
Redwood City, California, United States · On-site
$120k–$160k/yr
Senior$495M raised
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$120k–$160k/yr
Full-time
bachelor degree
Health Insurance, Dental Insurance, Vision Insurance, Disability Insurance, Life Insurance, Long-Term Care Insurance
Posted 8d ago
~40 hrs/week
Responsibilities
The Business Systems Engineer is responsible for the hands-on configuration, implementation, and optimization of enterprise applications across the organization. This role bridges the gap between business stakeholders and IT to ensure systems are deployed effectively while adhering to compliance and validation standards.
Requirements
Candidates must possess a bachelor's degree in Information Technology or a related field and at least 5 years of experience in biotech or pharmaceutical enterprise systems. Proficiency in cloud environments, ERP platforms, and GxP/SOX compliance principles is required.
Full job description
Rezolute is a late-stage rare disease biopharmaceutical company focused on developing transformative therapies for patients living with severe metabolic and endocrine disorders. Our lead investigational therapy, RZ358 (ersodetug), is a fully human monoclonal antibody in late-stage clinical development for the treatment of congenital and acquired forms of hyperinsulinism (HI). Rezolute’s mission is to bring hope and meaningful solutions to patients and families affected by rare diseases through scientific innovation, collaboration, and integrity.
The Business Systems Engineer - Enterprise Applications position is a hands-on technical contributor responsible for executing and supporting the implementation, integration, and optimization of enterprise and business systems across the organization.
This role bridges business stakeholders, vendors, and IT, ensuring systems are deployed effectively, align with operational needs, and adhere to compliance and validation standards. The Business Systems Engineer - Enterprise Applications works directly with technical environments and configurations—not just project coordination—to help bring systems online efficiently and correctly.
This individual collaborates closely with the Director of Quality Assurance- Computer Systems to ensure implementation activities align with validation requirements and reports to the Associate Director of IT, who oversees enterprise architecture, strategic planning, and IT roadmap execution.
The ideal candidate has experience in the biotech or pharmaceutical industry, particularly in organizations moving from clinical to commercial phases, and understands how to deliver systems that meet both business and compliance expectations.
\nKey Responsibilities:
Take a hands-on role in configuring, implementing, and supporting enterprise and business systems across departments.
Work with business stakeholders to capture requirements and translate them into technical and system configurations.
Lead cross-functional and IS/IT-centric projects, ensuring alignment between business stakeholders, vendors, and internal IT resources.
Collaborate with IT staff and external vendors to deploy, integrate, and optimize systems that support operational growth.
Partner with the CSV team to ensure implementation tasks align with validation processes, providing technical assistance (e.g., system setup, environment readiness, data preparation, and issue resolution).
Support and troubleshoot system integrations, user access issues, and environment dependencies within AWS and Azure ecosystems.
Participate in data migration and environment setup activities during system deployment.
Maintain detailed documentation of system configurations, workflows, and change controls.
Identify and escalate project risks, blockers, or dependencies to the Associate Director of IT.
Provide post-implementation support and assist in transitioning systems to steady-state ownership.
Qualifications:
Bachelor’s degree in Information Technology, Computer Science, or a related discipline (or equivalent experience).
Minimum of 5 years of experience implementing or supporting enterprise and business systems in biotech or pharmaceutical organizations.
Hands-on experience with platforms such as Veeva Vault, ERP systems (e.g., NetSuite, SAP, or Oracle), and cloud environments (AWS and Azure).
Familiarity with GxP, SOX, and data integrity principles.
Understanding of both clinical-phase and commercial-phase biotech operations.
Strong troubleshooting, analytical, and documentation skills.
Ability to manage multiple priorities and adapt to evolving business needs.
Excellent communication skills and ability to work cross-functionally across IT, QA/CSV, and business teams.
Core Competencies
Hands-On Executor: Comfortable configuring, testing, and deploying systems directly.
Collaborative Partner: Works effectively with IT, CSV, and business stakeholders to drive compliant implementations.
Analytical Problem-Solver: Identifies technical challenges and implements scalable solutions.
Detail-Oriented: Maintains precision in documentation and configuration management.
Clear Communicator: Provides concise updates and transparent reporting to leadership.
Adaptable: Operates effectively in a fast-paced, evolving biotech environment.
\n
Rezolute (RZLT) currently anticipates the base salary for the Business Systems Engineer - Enterprise Applications role could range from $120,000 to $160,000 and will depend, in part, on the successful candidate’s geographical location and their qualifications for the role, including education and experience. This position will also be eligible for an annual performance bonus in accordance with the terms of the applicable plan (depending, in part, on company and individual performance and at the Company’s discretion on an individual basis). The compensation described above is subject to change and could be higher or lower than the range described based on current market survey data and the qualifications, education, experience and geographical location of the selected candidate. Rezolute offers competitive compensation, stock options and a rich benefits package.
Qualifying employees are eligible to participate in benefit programs such as:
Health Insurance (Medical / Dental / Vision)
Disability, Life & Long-Term Care Insurance
Holiday Pay
Tracking Free Vacation Program
401(k) Plan Match
Educational Assistance Benefit
Fitness Center Reimbursement
We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.
Related keywords
BiopharmaceuticalRare diseaseEnterprise applicationsSystem integrationVeeva VaultERPNetSuiteSAPOracleAWSAzureGxPSOXData integrityComputer Systems ValidationCSV
Rezolute is developing transformative therapeutics for rare and metabolic diseases.
Industry
Biotechnology Research
Company size
51-200 employees
Headquarters
Redwood City, California
LinkedIn followers
12,975
Total funding
$495M
Rezolute is a late-stage rare disease company focused on significantly improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI).
For more information, visit: www.rezolutebio.com.
Offices: 275 Shoreline Dr., Ste. 500, Redwood City, California 94065, US
How much do Software jobs in Redwood City, CA pay?
Based on 204 listings with disclosed salaries, most software jobs in Redwood City, CA pay between $131k–$265k per year. Individual offers vary with seniority, company size, and specialization.
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There are currently 255 open software positions in Redwood City, CA listed on Clera. New openings are added daily as companies post roles.
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Companies currently hiring include Delinea, Luma, Box, C3 AI, Retell, among others. Browse the listings above to see every active employer.
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