Executive Director, Commercial Drug Product Manufacturing Operations
Redwood City, California, United States · On-site
$265k–$331k/yr
Senior+
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Skills: Commercial drug product manufacturing, Primary packaging, CMO management, Technology transfer, Process validation
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Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
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Sequoia Hospital - Dignity Health
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Redwood City, California, United States · On-site
$37/hr–$46/hr
Entry level
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Research Associate II, Clinical Biomarker Development
Redwood City, California, United States · Hybrid
$91k–$110k/yr
Entry level
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Skills: Cancer biology, Molecular biology, Cell biology, Quality control, Data analysis
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Redwood City, California, United States · Hybrid
$214k–$268k/yr
Senior+
Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, …
Skills: Technical program management, Imaging science, AI research, Cross-functional leadership, Project planning
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
The Chan Zuckerberg Initiative was founded in 2015 by Priscilla Chan and Mark Zuckerberg to harness the power of technology to pursue some of society’s most ambitious goals — from curing or preventing all disease to tran…
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For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases. Our commercial portfolio includes treatments…
Senior Manager, Commercial Manufacturing, Drug Substance
Redwood City, California, United States · Hybrid
$164k–$205k/yr
Senior+
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Skills: Drug substance manufacturing, Commercial manufacturing, Technology transfer, Process validation, GMP manufacturing
For more than 25 years, Corcept has been singularly focused on the science of cortisol, a powerful hormone that when unregulated, can play a role in a broad range of diseases. Our commercial portfolio includes treatments…
Skills: Strategic planning, Drug development, Market planning, Oncology, Competitive intelligence
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Where You’ll Work Founded in 1950, Dignity Health - Sequoia Hospital is a 208-bed, acute care, nonprofit hospital located in Redwood City, California. Serving over 50,000 patients annually, the hospital offers a full com…
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Computational Clinical Scientist II, Clinical Bioinformatics
Redwood City, California, United States · Hybrid
$132k–$166k/yr
Mid level
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Skills: Clinical Data Management, EDC Systems, UAT, Database Lock, CDISC
Executive Director, Commercial Drug Product Manufacturing Operations
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$265k–$331k/yr
Full-time
bachelor degree, postgraduate degree
Competitive cash compensation, Equity awards, Health benefits, Learning and development opportunities
Posted 4h ago
~40 hrs/week
Responsibilities
The Executive Director will lead commercial drug product manufacturing and primary packaging operations across external partners to ensure reliable supply. Responsibilities include overseeing technology transfer, process validation, continued process verification, and driving operational excellence initiatives.
Requirements
Candidates must possess a BS, MS, or PhD in a scientific or engineering discipline with at least 17 years of experience in pharmaceutical or biotechnology manufacturing. Strong expertise in managing CMOs, commercial manufacturing operations, and validation lifecycle activities is required.
Full job description
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
The Executive Director, Commercial Drug Product Manufacturing Operations will lead commercial drug product manufacturing and primary packaging activities within the Drug Product Development & Manufacturing organization.
The role will oversee execution of commercial manufacturing operations across external manufacturing and packaging partners to support reliable commercial supply and lifecycle management.
Responsibilities include commercial readiness activities, site qualification, technology transfer, process validation, PPQ execution, post-approval changes, troubleshooting, continued process verification (CPV), and operational excellence initiatives.
The role will also support execution of commercial process monitoring activities to ensure sustained process performance and product quality.
Responsibilities:
Develop and execute commercial manufacturing and primary packaging strategies supporting commercialization readiness, life cycle management, marketed products and future portfolio expansion.
Lead execution of commercial manufacturing and primary packaging operations across CMOs and packaging partners.
Lead implementation of post-approval manufacturing and packaging changes.
Lead execution of continued process verification (CPV) activities across commercial manufacturing operations.
Manage monitoring and trending of critical process parameters, process performance attributes, and product quality data.
Support qualification and onboarding of manufacturing and primary packaging sites.
Support commercial readiness activities including technology transfer, validation, and PPQ.
Provide leadership for investigations, troubleshooting, and deviation management activities.
Drive operational excellence initiatives focused on manufacturing performance and supply reliability.
Partner cross-functionally with Pharmaceutical Development, MSAT, Quality, Regulatory Affairs, and Supply Chain organizations.
Support commercialization and lifecycle management activities for marketed products.
Required Skills, Experience and Education:
BS/MS/PhD in Chemical Engineering, Pharmaceutical Sciences, Chemistry, or related scientific/engineering discipline.
17+ years of experience in pharmaceutical or biotechnology manufacturing, technical operations, or commercial operations with a strong track record of technical expertise and leadership.
Strong experience supporting commercial drug product manufacturing and primary packaging operations.
Demonstrated strong operational and cross-functional team leadership, as well as people management skills.
Experience managing CMOs and external manufacturing partners.
Experience supporting manufacturing process validation, packaging validation, PPQ execution, and validation lifecycle activities.
Experience supporting continued process verification (CPV) and commercial process monitoring programs.
Preferred Skills:
BS or MS degree in Chemical Engineering, Pharmaceutical Sciences, Chemistry, Biochemistry, or related engineering/scientific discipline; advanced degrees are valued but not required.
Demonstrated leadership responsibility for commercial drug product manufacturing operations supporting approved and marketed products.
Direct experience managing commercial supply, manufacturing performance, and lifecycle management for one or more commercial pharmaceutical products.
Proven track record of owning commercial manufacturing execution, including routine production, supply reliability, process monitoring, deviation management, and post-approval changes.
Experience leading external manufacturing networks and CMO relationships for commercial products from launch through lifecycle management.
Hands-on operational leadership experience within commercial manufacturing, technical operations, plant operations, or commercial MSAT organizations.
Experience making risk-based operational decisions impacting commercial product supply, compliance, and business performance.
Demonstrated success driving manufacturing performance improvements, capacity optimization, and operational excellence initiatives in a commercial environment.
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].
Base Pay Salary Range
$265,000—$331,000 USD
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.
Revolution Medicine enables physicians to integrate personalized medicine into their practices in order to more effectively treat patients.
Our genes play an important role in determining how we respond to about 75% of prescription drugs. Scientific research has demonstrated which genes predict these responses. According to the American Medical Association (AMA), 98% of physicians agree that knowing a patient’s genetic profile would help in prescribing medications. Yet, 90% of physicians do not feel they are adequately informed about how to apply genetic testing to treatment decisions.
Our mission is to improve the quality of patient care by helping doctors determine optimal treatment strategies and more accurately predict treatment responses. Revolution Medicine has developed ScriptMatch, an analytical process that enables physicians to easily incorporate genetic testing into their practices.
Our company solves a major issue in the clinical market and addresses an emerging trend in patient-driven healthcare: having clinical results that become part of the medical record and applicable to future treatments.
How much do Science & Research jobs in Redwood City, CA pay?
Based on 205 listings with disclosed salaries, most science & research jobs in Redwood City, CA pay between $109k–$265k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in Redwood City, CA right now?
There are currently 244 open science & research positions in Redwood City, CA listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Redwood City, CA?
Companies currently hiring include Revolution Medicine, Corcept Therapeutics, Luma, Abbott, Altos Labs, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Redwood City, CA?
Yes — 148 of the 244 open science & research positions offer remote or hybrid work (15 remote, 133 hybrid).
How do I apply for Science & Research jobs in Redwood City, CA?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.