Lexington, Massachusetts, United States · Hybrid
$260k–$325k/yr
Company Description About Bicycle Therapeutics Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved b…
Skills: Biostatistics, Clinical Study Design, Oncology Drug Development, Adaptive Designs, Bayesian Trial Design
Lexington, Massachusetts, United States · Hybrid
$260k–$325k/yr
Company Description About Bicycle Therapeutics Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved b…
Skills: Biostatistics, Clinical Study Design, Oncology Drug Development, Adaptive Designs, Bayesian Trial Design
Lexington, Massachusetts, United States · Hybrid
$260k–$325k/yr
Company Description About Bicycle Therapeutics Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved b…
Skills: Biostatistics, Clinical Study Design, Oncology Drug Development, Regulatory Advocacy, Adaptive Designs
Lexington, Massachusetts, United States · Hybrid
$260k–$325k/yr
Company Description About Bicycle Therapeutics Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved b…
Skills: Biostatistics, Clinical Study Design, Oncology Drug Development, Regulatory Advocacy, Adaptive Designs
Lexington, Massachusetts, United States · On-site
Job Summary The Administrative Assistant II provides administrative support to the Associate Vice President and Chief Information Officer (CIO) as well as other unit leaders in the University Information Technology Servi…
Skills: Budget Administration, Project Coordination, Calendar Management, Payroll, Microsoft Office
Lexington, Massachusetts, United States · Hybrid
$80k–$157k/yr
Georgetown University comprises two unique campuses in the nation’s capital. With the Hilltop Campus located in the heart of the historic Georgetown neighborhood, and the Capitol Campus, just minutes from the U.S. Capito…
Skills: Financial Analysis, Budgeting, Forecasting, Business Analytics, Team Management
Lexington, Massachusetts, United States · On-site
The role of the Chair of Department of Pediatric Dentistry is multifaceted and carries significant responsibilities. The Department Chair is responsible for providing the overall vision for the department, clinical, acad…
Skills: Strategic Thinking, Clinical Leadership, Academic Leadership, Research Oversight, Financial Management
Lexington, Massachusetts, United States · On-site
Ranked #1 for Safety, Quality and Patient Satisfaction, Jupiter Medical Center is the leading destination for world-class health care in Palm Beach County and the greater Treasure Coast. Outstanding physicians, state-of-…
Skills: Cardiac Rhythm Interpretation, Cardiac Monitoring, BLS Certification, Patient Observation, Clinical Documentation
Lexington, Massachusetts, United States · On-site
Ranked #1 for Safety, Quality and Patient Satisfaction, Jupiter Medical Center is the leading destination for world-class health care in Palm Beach County and the greater Treasure Coast. Outstanding physicians, state-of-…
Skills: Plant Operations Management, HVAC, Plumbing, Electrical Systems, Emergency Management
Lexington, Massachusetts, United States · Hybrid
$90k–$100k/yr
*The Lexington Symphony, in partnership with Insource Services Inc., is conducting a search for its next Executive Director.* ABOUT THE ORGANIZATION Lexington Symphony is a professional orchestra of accomplished musician…
Skills: Fundraising, Strategic Planning, Nonprofit Management, Grant Writing, Donor Stewardship
Lexington, Massachusetts, United States · On-site
$154k–$243k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Human Factors Engineering, Human Centered Design, User Research, AI-enabled HFE, Risk Management
Lexington, Massachusetts, United States · On-site
Ranked #1 for Safety, Quality and Patient Satisfaction, Jupiter Medical Center is the leading destination for world-class health care in Palm Beach County and the greater Treasure Coast. Outstanding physicians, state-of-…
Skills: Compounding, Medication Dispensing, IV Admixtures, Clinical Pharmacy Services, Pharmacy Technician Supervision
Lexington, Massachusetts, United States · Hybrid
$116k–$182k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: DAM Administration, Content Management, Taxonomy Management, Metadata Configuration, Workflow Optimization
Lexington, Massachusetts, United States · On-site
If you are a current University of Northern Iowa employee and would like to apply for this position, login to UNI Works and type “Find Jobs” in the search bar to view and apply for open positions. Full Consideration Date…
Skills: Academic Advising, Student Success, Staff Management, Course Planning, Interpersonal Communication
Lexington, Massachusetts, United States · On-site
$84k/yr
If you are a current University of Northern Iowa employee and would like to apply for this position, login to UNI Works and type “Find Jobs” in the search bar to view and apply for open positions. Full Consideration Date…
Skills: Clinical Supervision, Crisis Management, Psychological Assessment, Triage Screening, Individual Counseling
Lexington, Massachusetts, United States · On-site
$113k–$257k/yr
FMS Mission Planning Systems Engineer, Lead The Opportunity: Serve as the Lead FMS Systems Engineer supporting Foreign Military Sales (FMS) Mission Planning programs within the Airspace Mission Planning (AMP) enterprise.…
Skills: Systems Engineering, Foreign Military Sales, Mission Planning Systems, Requirements Decomposition, Technical Evaluation
Lexington, Massachusetts, United States · On-site
$200k–$450k/yr
If you are a current University of Northern Iowa employee and would like to apply for this position, login to UNI Works and type “Find Jobs” in the search bar to view and apply for open positions. Full Consideration Date…
Skills: Academic Leadership, Curriculum Development, Research Expertise, Oral Communication, Written Communication
Lexington, Massachusetts, United States · On-site
Ranked #1 for Safety, Quality and Patient Satisfaction, Jupiter Medical Center is the leading destination for world-class health care in Palm Beach County and the greater Treasure Coast. Outstanding physicians, state-of-…
Skills: Clinical Management, Staffing Coordination, Performance Reviews, Patient Care Planning, Evidence-Based Practice
Lexington, Massachusetts, United States · On-site
Job Description: Who We Are Seattle Pacific University is a Christian university fully committed to engaging the culture and changing the world by graduating people of competence and character, becoming people of wisdom,…
Skills: Executive Administrative Support, Calendar Management, Donor Relationship Management, Event Planning, Budget Administration
Lexington, Massachusetts, United States · On-site
Welcome to Furman University's Career Site! IMPORTANT: Load all documents in the My Experience area under Resume/CV. This may include your resume/C.V., cover letter, unofficial transcript, teaching philosophy, etc. Plea…
Skills: Marketing Strategy, Event Planning, Social Media Management, Content Creation, Project Management
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The VP of Biometrics is responsible for building and overseeing the biometrics organization, ensuring the integrity of clinical study designs and statistical methodologies. This role involves leading interactions with global health authorities and managing the statistical strategy for oncology and radiopharmaceutical pipelines.
Requires a PhD or Master's degree with extensive experience leading biometrics functions in oncology drug development from Phase I to III. Candidates must possess deep expertise in advanced statistics, regulatory guidelines, and proficiency in SAS, R, and Python.
About Bicycle Therapeutics
Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle® molecules attractive candidates for drug development. The company is evaluating nuzafatide pevedotin (formerly BT5528), a Bicycle® Drug Conjugate (BDC®) targeting EphA2, a historically undruggable target; a pipeline of Bicycle® Radioconjugates (BRCs) and imaging agents;; zelenectide pevedotin (formerly BT8009), a BDC® targeting Nectin-4, a well-validated tumor antigen; and, through various partnerships, the use of Bicycle® technology to develop therapies to treat diseases in a range of therapeutic areas.
Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Lexington, Massachusetts, USA. For more information, visit bicycletherapeutics.com
Culture is key and all Bicycle employees actively embrace and role model our company values:
The Vice President, Biometrics will build, resource, oversee, and play a hands on role for the Biometrics organization. This leader holds ultimate accountability for clinical study designs, statistical methodologies, data analysis, and interpretation of results in close collaboration with partner functions across Clinical Development, Operations, and Regulatory Affairs.
As a key member of the Development Leadership Team, the VP provides strategic statistical input into Bicycle's drug development portfolio, representing the company in interactions with global Health Authorities (FDA, EMA, MHRA, RoW agencies) and contributing to the advancement of our oncology and radiopharmaceutical clinical pipelines. Additionally, this role supports early-stage research and translational sciences as required.
The ideal candidate possesses deep global clinical development expertise in oncology, combined with an outstanding track record of managing complex portfolios, driving innovation in applied statistical methodologies (including adaptive designs), and leading teams in a high-growth, agile biotechnology environment. Experience in Bayesian Trial design and radiopharmacology experience is preferred.
KEY RESPONSIBILITIES
We have shared the expected recruitment base pay range for this full-time position based on the anticipated location. The actual base pay will depend on several factors unique to each candidate, including skills, qualifications, experience, and the actual location of the role. At Bicycle, base pay is just one component of the total reward package. This role is also eligible for Bicycle’s discretionary annual bonus program (or sales incentive program), its comprehensive health and retirement benefit programs, and equity grants. During the hiring process, your Bicycle recruiter can share more about the Company’s total reward package.
Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.
Precision-Guided Therapeutics
Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company that is harnessing the power of bicyclic peptides and leveraging Nobel Prize-winning science to develop a new and differentiated class of medicines to treat cancer and other diseases. Bicycle® molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin, previously BT8009, a Bicycle® Toxin Conjugate (BTC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radio Conjugates (BRC™) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology. Bicycle is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Lexington, MA.
Offices: Granta Park, Cambridge, England CB21 6GP, GB · 4 Hartwell Place, Lexington, Massachusetts 02421, US
Based on 126 listings with disclosed salaries, most management & leadership jobs in Lexington, MA pay between $72k–$243k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 215 open management & leadership positions in Lexington, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Kiniksa Pharmaceuticals, Takeda, Georgetown University Center on Education and the Workforce, FGCU Daveler & Kauanui School of Entrepreneurship, MIT Lincoln Laboratory, among others. Browse the listings above to see every active employer.
Yes — 38 of the 215 open management & leadership positions offer remote or hybrid work (2 remote, 36 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
