Boston, Massachusetts, United States · Hybrid
$188k–$282k/yr
Job Description Vertex is seeking a Senior Principal AI Engineer to design, build, and optimize the shared platform capabilities that power AI-enabled products and intelligent workflows across the enterprise. Working wit…
Skills: AI platform architecture, Generative AI, Large language models, Agentic workflows, Orchestration frameworks
Boston, Massachusetts, United States · Remote OK
Sartorius has a position for a Field Application Specialist, candidates for this remote based position will provide high-level, in-depth technical support and expertise to customers using Sartorius BioAnalytics products …
Skills: Technical support, Live-cell analysis, Product demonstrations, Customer training, Experimental optimization
Boston, Massachusetts, United States · On-site
$18/hr–$25/hr
Thank you for your interest in a career at NeighborHealth, formerly East Boston Neighborhood Health Center! As one of the largest community health centers in the country, NeighborHealth is proud to serve the greater Bost…
Skills: Customer service, Data entry, Insurance verification, Electronic medical record, Epic
Boston, Massachusetts, United States · On-site
$23/hr–$31/hr
When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives. Beth Israel Lahey Health and New England Baptist Hospital are devoted to consistently promoting a culture o…
Skills: Pharmacy operations, Sterile compounding, Aseptic technique, Inventory management, Controlled substances handling
Boston, Massachusetts, United States · On-site
Job Summary At Koala Health, we have our eyes set on an ambitious goal: to make managing your pet’s health simple and delightful. We’ve already launched our pharmacy service that allows people to shop for their pets’ med…
Skills: Pharmacy operations, Medication processing, Attention to detail, Multitasking, Communication skills
Boston, Massachusetts, United States · Remote Solely
LICENSED DOCTOR OF OPTOMETRY - MASSACHUSETTS LICENSED Tele-Optometry provides an exciting opportunity! Teleoptometric Service, P.C. provides a comprehensive eye exam to patients using our patented remote technology. This…
Skills: Optometry, Tele-optometry, Eye examination, Prescription generation, Patient communication
Boston, Massachusetts, United States · On-site
$21/hr–$29/hr
Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As …
Skills: Clinical Research, Biospecimen Collection, Data Acquisition, REDCap, Protocol Compliance
Boston, Massachusetts, United States · On-site
$39/hr–$93/hr
POSITION SUMMARY: The Registered Nurse provides nursing care that has as its ultimate concern supporting the total person and promoting adaptation of the individual. This is accomplished by counseling, teaching, direct c…
Skills: Nursing care, Patient assessment, Counseling, Patient teaching, Medical-surgical nursing
Boston, Massachusetts, United States · On-site
$174k–$262k/yr
The Thought Leader Liaison (TLL) role is a senior field-based position within the US commercial organization that will focus on commercial KOL relationship engagement, promotional speaker training and development, and su…
Skills: KOL engagement, Product marketing, Field sales, Clinical knowledge, Strategic planning
Boston, Massachusetts, United States · Hybrid
$70k–$120k/yr
Join us as we work to create a thriving ecosystem that delivers accessible, high-quality, and sustainable healthcare for all. Role summary: Join our Global Tax Department as a Senior Tax Associate, where you will play a …
Skills: Tax compliance, Tax research, Tax provision preparation, SOX compliance, Data analysis
Boston, Massachusetts, United States · On-site
$41/hr–$105/hr
Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our missio…
Skills: Intensive Care Unit Nursing, Clinical Practice, Patient Care, Critical Care, Nursing
Boston, Massachusetts, United States · On-site
$23/hr–$33/hr
Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As …
Skills: Inventory management, Medical device tracking, Sterile processing, Aseptic technique, Equipment troubleshooting
Boston, Massachusetts, United States · On-site
$127k–$174k/yr
Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our missio…
Skills: Surgical oncology, Clinical assessment, Patient care, Wound care, First-assist
Boston, Massachusetts, United States · On-site
$54k–$81k/yr
Job Description: I. Position Summary: HSL provides enhanced housing with services to seniors living in its four affordable housing locations, and at partner housing sites, with the goal of improving quality of life and s…
Skills: Case Management, Care Coordination, Wellness Assessment, Patient Advocacy, Bilingual Communication
Boston, Massachusetts, United States · On-site
$39/hr–$93/hr
Position: Registered Nurse Location: Float Pool, Schedule: Per Diem POSITION SUMMARY Med/Surge Float RNs provide 24/7 clinical excellence for med/surge areas. Nurses must be flexible and versatile. The Float Pool provide…
Skills: Nursing care, Patient assessment, Clinical excellence, Medical surgical nursing, Patient education
Boston, Massachusetts, United States · On-site
$26/hr
Site: Spaulding Nursing and Therapy Center Brighton, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advan…
Skills: Communication skills, Service delivery, Attention to detail, Computer proficiency, Nutritional assessment
Boston, Massachusetts, United States · On-site
$17/hr–$29/hr
Job Summary: Shields Health Care Group is a leading medical provider in New England, operating in one of the most fascinating business environments today – Healthcare. Our world-class team is made up of innovative thinke…
Skills: Patient Care, Medical Environment Support, Patient Interviewing, Safety Protocols, Data Entry
Boston, Massachusetts, United States · Hybrid
$124k–$185k/yr
Who We Are Verily Health is a data platform and technology company purpose-built to power AI-enabled precision health solutions that accelerate research and improve care for individuals and communities. Uniquely position…
Skills: UX Design, Interaction Design, Visual Design, Figma, User Research
Boston, Massachusetts, United States · On-site
$18/hr–$27/hr
Under the direction and supervision of the registered nurse and in accordance with hospital policies, procedures, protocols, and standards of practice, the Certified Nursing Assistant (CNA) participates in the delivery o…
Skills: Patient care, Vital signs monitoring, Clinical documentation, Hygiene assistance, Patient ambulation
Boston, Massachusetts, United States · On-site
$31/hr–$50/hr
Site: Massachusetts Eye and Ear Infirmary Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. …
Skills: Surgical Technology, Sterile Processing, Operating Room Assistance, Patient Preparation, Instrument Handling
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The Senior Principal AI Engineer will architect and develop shared platform services to enable the creation, integration, and management of agentic AI solutions across the enterprise. This role involves establishing reusable frameworks, SDKs, and governance controls to accelerate AI adoption while ensuring production-grade reliability and performance.
Candidates must possess significant industry experience in software or AI platform engineering with a proven track record of delivering production-scale systems. A bachelor's degree in a technical field is required, with a deep understanding of distributed systems, generative AI, and enterprise-level software engineering best practices.
Vertex is seeking a Senior Principal AI Engineer to design, build, and optimize the shared platform capabilities that power AI-enabled products and intelligent workflows across the enterprise. Working within the Agentic AI Platform team, this role will focus on delivering production-grade platform services for model integration, prompt and workflow orchestration, evaluation, observability, performance optimization, and agent lifecycle management.
A key focus of this role will be enabling a build/bring-your-own-agents capability within the Agentic AI Platform, allowing teams across Vertex to create, integrate, customize, and operationalize their own agents using shared platform standards, tooling, and governance controls.
The ideal candidate combines strong software engineering fundamentals with deep experience in applied AI systems. This individual will be comfortable operating across rapid experimentation and engineering rigor, translating emerging AI capabilities into scalable, reliable, secure, and reusable platform components. The Senior Principal AI Engineer will play a critical leadership role in accelerating AI adoption across Vertex by enabling product teams to build and deploy AI solutions faster and more effectively.
Key Responsibilities
Build/bring-your-own-agents capability (primary focus): the frameworks, SDKs, templates, interfaces, and guardrails that let teams across Vertex create, integrate, customize, and operationalize their own agents on shared platform standards
Platform services: model integration, prompt and workflow orchestration, tool use, memory patterns, and agentic task coordination that other teams build against
Agent lifecycle and quality: registration, configuration, testing, deployment, versioning, monitoring, and retirement, plus the evaluation and benchmarking frameworks behind them
Developer experience: self-service onboarding, documentation, reference implementations, and enablement resources that shorten the path from idea to production
Standards and technical leadership: platform APIs, service contracts, architecture patterns, and the engineering practices that keep custom agents safe, reliable, and supportable
Architect and develop shared AI/agentic platform services that support enterprise AI products and internal workflows
Design and implement a build/bring-your-own-agents capability that enables teams to create, register, integrate, deploy, and manage their own agents within the enterprise agentic platform
Establish reusable frameworks, SDKs, templates, interfaces, and guardrails that standardize how custom agents are built and onboarded onto the platform
Own the developer experience for the platform, delivering intuitive self-service onboarding, SDKs, CLIs, sandbox environments, reference implementations, and clear documentation that let builders move from idea to production quickly
Define agent lifecycle capabilities including agent registration, configuration, testing, deployment, monitoring, versioning, and retirement
Build and maintain robust integrations with foundation models, model gateways, APIs, enterprise tools, and related AI infrastructure
Design and implement systems for prompt orchestration, workflow execution, tool use, memory patterns, and agentic task coordination
Develop reusable frameworks and services for evaluation, benchmarking, and validation of AI model, agent, and workflow performance
Establish platform capabilities for observability, monitoring, tracing, logging, and alerting across AI workloads and autonomous agent interactions
Optimize platform performance, scalability, latency, reliability, and cost efficiency for production AI and agentic systems
Partner with product, data, engineering, security, and architecture teams to enable enterprise-ready AI solutions
Translate prototypes and experimental concepts into hardened, maintainable, production-grade services
Define engineering standards, best practices, and design patterns for AI platform development and deployment
Support governance, risk management, and responsible AI practices through measurable controls, policy enforcement, and technical safeguards for agent behavior
Drive platform adoption by creating reusable components, documentation, onboarding patterns, and developer enablement resources
Mentor engineers and provide technical leadership across AI platform initiatives
Evaluate emerging tools, frameworks, and architectural patterns in generative AI and agentic systems to inform platform strategy
Required Qualifications
Bachelor’s degree in Computer Science, Software Engineering, Machine Learning, Data Engineering, or a related technical field; advanced degree preferred
Significant industry experience in software engineering, machine learning engineering, or AI platform development, including experience in senior or principal-level technical roles
Proven track record designing and delivering production-scale AI or ML platforms
Strong experience building distributed systems, APIs, microservices, and cloud-native applications
Demonstrated experience operationalizing machine learning, generative AI, or agent-based solutions in enterprise environments
Experience designing extensible platform capabilities that enable internal teams to build or integrate custom applications, tools, or services
Deep understanding of software engineering best practices including testing, CI/CD, version control, code review, and system reliability
Deep understanding of AI-native software engineering practices and experience establishing standards, governance, and best practices for the responsible use of AI coding assistants and software engineering agents across engineering teams
Experience defining architecture, standards, and reusable services for large-scale enterprise environments
Experience leading complex technical initiatives and influencing architecture across cross-functional teams
Strong communication skills with the ability to explain complex technical concepts to varied audiences
Experience balancing experimentation speed with production engineering discipline, security, and maintainability
Technical Skills Required
AI/ML platform architecture
Generative AI systems and large language model integration
Agentic workflows and orchestration frameworks
Multi-agent or autonomous agent system design
Prompt engineering and prompt management
Workflow orchestration and automation
Agent lifecycle management
Model evaluation, benchmarking, and performance measurement
AI observability, tracing, monitoring, and logging
API design and service integration
Distributed systems and scalable backend engineering
Cloud platforms and cloud-native deployment patterns
Productionization of AI/ML services
Reliability, latency, throughput, and cost optimization
CI/CD pipelines and DevOps/MLOps practices
Secure software development and enterprise platform controls
Preferred Skills
Advanced degree in Computer Science, Artificial Intelligence, Machine Learning, or a related discipline
Experience with enterprise AI platforms, developer platforms, or internal tooling ecosystems
Experience building frameworks or platforms that support bring-your-own-component or extensible developer patterns
Demonstrated focus on developer experience, including designing self-service onboarding, SDKs, CLIs, sandboxes, templates, and documentation that reduce friction and accelerate time-to-first-deployment for internal builders
Familiarity with model gateways, retrieval-augmented generation, and evaluation frameworks
Experience implementing AI governance, responsible AI controls, and compliance-oriented technical solutions
Knowledge of vector databases, knowledge retrieval systems, and orchestration layers for intelligent applications
Experience in regulated industries such as biotechnology, pharmaceuticals, healthcare, or life sciences
Strong mentoring and technical leadership experience in highly collaborative environments
Ability to assess emerging AI technologies and translate them into practical platform capabilities
#LI-HYBRID
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
When it has to be right, you Vertex™.
Vertex is the Decision-to-Defense™ global indirect tax and compliance company. We help enterprises control indirect tax and compliance across the transaction lifecycle-so outcomes can be proved and improved with confidence. Our purpose is to ensure businesses and communities thrive through trusted transactions. Global compliance now lives inside the transaction. So does Vertex-helping enterprises prove outcomes from determination to defense.
Offices: 2301 Renaissance Blvd, King of Prussia, PA 19406, US · 40 Shuman Blvd., Suite 218, Naperville, IL 60540, US · 1 Furzeground Way, Stockley Park, Stockley Park, Uxbridge UB11 1EZ, GB · 101 Arthur Andersen Parkway, Suite 300, Sarasota, FL 34232, US · Gustav Mahlerplein, Amsterdam, North Holland 1082, NL
There are currently 4,574 open healthcare positions in Boston, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Mass General Brigham, BOSTON MEDICAL CENTER, BOSTON, Anna Jaques Hospital, Vertex Inc., CVS Health, among others. Browse the listings above to see every active employer.
Yes — 1351 of the 4574 open healthcare positions offer remote or hybrid work (328 remote, 1023 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
