San Diego, California, United States · Hybrid
$175k–$190k/yr
Senior Staff Scientist, Assay Development (Verification and Validation) Location: San Diego, CA Job Type: Full-Time Salary: $175,000 - $190,000 Position Overview We are seeking a Senior Staff Scientist to provide technic…
Skills: Assay Development, Analytical Verification, Analytical Validation, Design Control, LDT Development
San Diego, California, United States · On-site
Position summary: The Site Supervisor will be responsible for the day-to-day operations at our project locations. Working closely with project managers, you will manage the day-to-day operation of the job site from launc…
Skills: Site Supervision, Project Coordination, Subcontractor Management, Budget Management, Scheduling
San Diego, California, United States · Remote OK
$75k/yr
** Security Clearance Required Company Overview Systems Technology Forum LTD (STF) is an established industry partner with a passion for exceptional performance and an unwavering commitment to our clients. As a premier p…
Skills: Integrated Logistics Support, Installation Planning, Training Planning, Configuration Management, Product Support Management
Los Angeles, California, United States · Remote Solely
$60k–$80k/yr
TELUS Health is empowering every person to live their healthiest life. Guided by our vision, we are leveraging the power of our leading edge technology and focusing on the uniqueness of each individual to create the futu…
Skills: Windows Server, IIS Server, SQL Server, PowerShell, Active Directory
San Diego, California, United States · On-site
$83k–$132k/yr
Please Note: 1. If you are a first time user, please create your candidate login account before you apply for a job. (Click Sign In > Create Account) 2. If you already have a Candidate Account, please Sign-In before you …
Skills: C++, Golang, Python, Linux Internals, Kubernetes
San Diego, California, United States · On-site
$144k–$204k/yr
Signal Integrity and Power Integrity (SIPI) Engineers at Meta design, analyze, and validate SIPI aspects of electrical systems for next-generation hardware products and platforms. They collaborate with multidisciplinary …
Skills: Signal Integrity, Power Integrity, EM Simulation, Cadence Sigrity, Ansys HFSS
San Diego, California, United States · On-site
$131k–$237k/yr
Leidos has a new and exciting opportunity for a Sr. RMF Security Engineer in our National Security Sector's (NSS) Cyber & Analytics Business Area (CABA). Our talented team is at the forefront in Security Engineering, Com…
Skills: Risk Management Framework, Cybersecurity, Information Assurance, Security Assessment, Vulnerability Scanning
San Diego, California, United States · On-site
Product and Manufacturing Test Engineering Manager (Accenture LLP; San Diego, CA): Accenture LLP has multiple openings for the position of Product and Manufacturing Test Engineering Manager in San Diego, CA, and the job …
Skills: System-level Validation, Embedded Technology, Consumer Technology Platforms, Regression Testing, Defect Investigation
San Diego, California, United States · On-site
$23/hr–$39/hr
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Skills: CMM Programming, ZEISS Calypso, GD&T, Dimensional Inspection, OMM Operation
San Diego, California, United States · Hybrid
$189k–$246k/yr
Department: 107100 Quality Location: San Diego, USA- Remote Be a part of a global team that is inspired to make a difference in the lives of people living with rare disease. At Travere Therapeutics, we recognize that our…
Skills: Quality Assurance, GMP Compliance, Validation, Contract Service Provider Oversight, Risk Management
San Diego, California, United States · Hybrid
$150k–$195k/yr
Department: 106800 Technical Operations Location: San Diego, USA- Remote Be a part of a global team that is inspired to make a difference in the lives of people living with rare disease. At Travere Therapeutics, we recog…
Skills: Microbial Fermentation, Downstream Processing, CDMO Management, Process Performance Qualification (PPQ), Biologics License Application (BLA)
San Diego, California, United States · On-site
$122k–$195k/yr
Please Note: 1. If you are a first time user, please create your candidate login account before you apply for a job. (Click Sign In > Create Account) 2. If you already have a Candidate Account, please Sign-In before you …
Skills: GoLang, Python, C++, Microservices, gRPC
San Diego, California, United States · On-site
$35/hr–$45/hr
Position Description Directly support the Naval Air Systems Command (NAVAIR), F/A-18 & EA-18G Fleet Support Team (FST) at Fleet Readiness Center Southwest (FRCSW) Naval Air Station (NAS) North Island, California. Duties …
Skills: Logistics Coordination, Inventory Control, Procurement, Kitting Operations, Technical Analysis
San Diego, California, United States · On-site
$33/hr–$39/hr
Join Our Team! Sunbelt Rentals strives to be the customer's first choice in the equipment rental industry. From pumps to scaffolding to general construction tools, we aim to be the only call needed to outfit a job site w…
Skills: Diesel Equipment Repair, Heavy Construction Equipment Repair, Hydraulic Systems Troubleshooting, Electrical Systems Troubleshooting, Preventive Maintenance
San Diego, California, United States · On-site
$97k–$131k/yr
Type of Requisition: Pipeline Clearance Level Must Currently Possess: Secret Clearance Level Must Be Able to Obtain: Secret Public Trust/Other Required: None Job Family: Logistics Job Qualifications: Skills: Leadership, …
Skills: Leadership, Maintenance Management, Maintenance Processes, Preventative Maintenance Programs, Technical Training
San Diego, California, United States · Hybrid
$156k–$260k/yr
Where Ambition Meets Innovation Build a career that matches all your initiative with an impressive dose of innovation. From cutting-edge resources and a collaborative environment to the freedom to make an impact and more…
Skills: Cloud-Native Architecture, API Design, Data Integration, React, Angular
San Diego, California, United States · On-site
$41/hr–$68/hr
Where Ambition Meets Innovation Build a career that matches all your initiative with an impressive dose of innovation. From cutting-edge resources and a collaborative environment to the freedom to make an impact and more…
Skills: Network Engineering, Cisco Routing, Cisco Switching, Wireless Networking, MPLS
San Diego, California, United States · On-site
$193k–$289k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > Software Engineering General Summary: As a leading technology innovator, Qualcomm pushes the boundaries of what's possible to enable nex…
Skills: C, C++, Linux Kernel, Board Support Packages, Embedded Linux
San Diego, California, United States · On-site
$117k–$175k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > Graphics Software Engineering General Summary: Interested in enabling next generation graphics, games, ray tracing, machine learning, im…
Skills: C++, C, GPU Hardware, Graphics Concepts, Vulkan
San Diego, California, United States · On-site
$180k–$271k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > Packaging Engineering General Summary: The Qualcomm Package Electrical Team has an opening in the areas of signal integrity and power in…
Skills: Signal Integrity, Power Integrity, Package Extraction, System Simulation, DDR Analysis
San Diego, California, United States • Hybrid
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Lead the analytical verification and validation strategy for laboratory-developed tests (LDTs) under design control. This includes designing performance studies, authoring quality documentation, and collaborating cross-functionally from design input through product launch.
Requires a PhD with 10+ years or a BS/MS with 15+ years of industry experience in molecular biology or biotechnology. Must have demonstrated expertise in advancing LDTs through validation in regulated clinical environments like CLIA or CAP.
Location: San Diego, CA
Job Type: Full-Time
Salary: $175,000 - $190,000
We are seeking a Senior Staff Scientist to provide technical leadership for assay development under design control, with primary responsibility for analytical verification and validation of laboratory-developed tests (LDTs). This role will set validation strategy, translate product and clinical requirements into rigorous study plans and acceptance criteria, and ensure high-quality execution and documentation in a regulated environment.
The successful candidate will combine strategic scientific leadership with a willingness to perform hands-on laboratory work. The role partners closely with R&D, Product Management, Clinical, Lab Operations, Bioinformatics, Software, Quality, and Regulatory throughout the product development lifecycle, from design inputs through launch and post-launch improvements.
Own or co-own design verification and analytical validation strategy for assigned assays, including study design, sample and replicate plans, acceptance criteria, statistical approach, execution, data interpretation, and final reports.
Design and lead analytical performance studies, as applicable, including accuracy, precision and reproducibility, analytical sensitivity and specificity, limit of detection, linearity or reportable range, interference, carryover, contamination risk, stability, robustness, and method or instrument equivalency.
Partner with Product Management, Clinical, and Regulatory to translate intended use, product requirements, and clinical needs into clear, testable design inputs and verification or validation methods.
Maintain traceability among user needs, design inputs, design outputs, risk controls, test methods, protocols, results, and design changes.
Perform and/or directly supervise hands-on laboratory work for critical experiments, method troubleshooting, and analytical validation studies.
Author and review high-quality development and quality documentation, including study plans, protocols, reports, SOPs, work instructions, technical assessments, deviations, investigations, and change-control records.
Communicate technical risks, tradeoffs, recommendations, and decisions clearly to cross-functional stakeholders and company leadership.
Mentor junior scientists and establish high standards for experimental design, data integrity, documentation quality, and scientific communication.
Required:
Degree in Molecular Biology, Biochemistry, Biotechnology, or related discipline.
PhD with 10+ years of relevant industry experience or BS/MS with 15+ years of relevant industry experience.
Demonstrated experience advancing LDT products from development through analytical validation, transfer, and launch.
Substantial hands-on experience designing, executing, analyzing, and documenting analytical verification and validation studies for LDTs.
Strong working knowledge of design controls, risk management, cGMP principles, and ISO 13485-aligned quality systems.
Experience working in a regulated clinical laboratory and/or diagnostic product-development environment, such as CLIA, CAP, or New York State-regulated laboratories.
Proven ability to generate and critically review high-quality technical and quality documentation suitable for audits, inspections, and regulatory review.
Demonstrated ability to lead complex cross-functional initiatives and influence scientific, engineering, operational, quality, and regulatory stakeholders without direct authority.
Strong scientific judgment, structured problem-solving skills, and clear written and verbal communication.
Willingness and ability to perform hands-on laboratory work as program needs require.
Demonstrated commitment to mentoring and developing scientists.
Preferred:
Experience with high-complexity NGS assays.
Experience supporting regulatory interactions, submissions, or reimbursement evidence packages, including MolDX, in partnership with Quality and Regulatory.
Experience with automated or high-throughput assay workflows and transfer into regulated clinical laboratory operations.
Familiarity with CLSI guidance and statistical methods used in analytical performance evaluation.
A center for entrepreneurial innovation at the intersection of AI and data science
Foresite Labs creates companies at the intersection of AI/machine learning and science. We believe AI, generative AI, and data science—when applied with scientific rigor—can accelerate discovery and drive innovations that benefit humanity. We provide the foundation for bold ideas to take shape and accelerate, shaping a better future for all. We offer competitive salaries, excellent benefits, and a flexible work environment where employees learn from top thinkers across multiple disciplines. With headquarters in San Francisco and Boston, we’re building a culture where scientific rigor meets entrepreneurial ambition. Foresite Labs Values Truth over progression: We follow the science, pursuing ideas that are grounded in data and abandoning them when not supported by the evidence. Take good risks: Our culture values informed risk-taking: good decisions are celebrated even when they result in bad outcomes. Everyone feels safe to contribute ideas and to learn from failure. Single accountable person: The project team lead is accountable for all decisions and for maintaining transparency and information flow within the team; we trust the project teams. The Review Committee unlocks capital and sets directions. Simplicity and Focus: “Companies die from indigestion, not starvation” (Bill Hewlett) We will focus on a few ideas aggressively and minimize all other distractions. Everyone will have a few key goals that have measurable outcomes. Respect and Community: Our employees are our greatest asset; everyone invests in creating an environment of collaboration and respect. We support their careers and career development whether they stay, go to a Labs company, or end up somewhere else.
Offices: 601 California St, Suite 600, San Francisco, California 94108, US · 625 Massachusetts Ave, 2nd Floor, Cambridge, MA 02139, US
Based on 2554 listings with disclosed salaries, most engineering jobs in San Diego, CA pay between $79k–$211k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 2,943 open engineering positions in San Diego, CA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Qualcomm, Northrop Grumman, Northrop Grumman Mission Systems, Inc., Apple, Solar Turbines, among others. Browse the listings above to see every active employer.
Yes — 566 of the 2943 open engineering positions offer remote or hybrid work (100 remote, 466 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
