San Diego, California, United States · Hybrid
$175k–$190k/yr
Senior Staff Scientist, Assay Development (Verification and Validation) Location: San Diego, CA Job Type: Full-Time Salary: $175,000 - $190,000 Position Overview We are seeking a Senior Staff Scientist to provide technic…
Skills: Assay Development, Analytical Verification, Analytical Validation, Design Control, LDT Development
San Diego, California, United States · Hybrid
$110k–$120k/yr
Scientist II, Protein Expression and Purification Location: San Diego, CA Job Type: Full-Time Compensation: $110,000 to $120,000 About Us We are a venture-backed, stealth-stage biotechnology company based in San Diego, f…
Skills: Protein Expression, Protein Purification, Biochemical Assays, Spectroscopic Assays, Fluorescence-based Assays
San Diego, California, United States · On-site
Position summary: The Site Supervisor will be responsible for the day-to-day operations at our project locations. Working closely with project managers, you will manage the day-to-day operation of the job site from launc…
Skills: Site Supervision, Project Coordination, Subcontractor Management, Budget Management, Scheduling
San Diego, California, United States · Hybrid
$110k–$120k/yr
Scientist II, Assay Development Location: San Diego, CA Job Type: Full-Time Salary $110,000 - $120,000 About Us We are a venture-backed, stealth-stage biotechnology company based in San Diego, focused on developing novel…
Skills: Library Preparation, Next-Generation Sequencing, Molecular Biology, Biochemistry, Experimental Design
San Diego, California, United States · Hybrid
At PMAT, we work on mission critical systems that directly support the warfighter, designing, building, and securing modern digital capabilities across cloud, data, and software environments. Our teams tackle complex, re…
Skills: Network Engineering, SD-WAN, RMF, Cybersecurity, Network Topology
San Diego, California, United States · On-site
$66k–$70k/yr
JLL empowers you to shape a brighter way. Our people at JLL are shaping the future of real estate for a better world by combining world class services, advisory and technology for our clients. We are committed to hiring …
Skills: HVAC Maintenance, Electrical Troubleshooting, Backup Power Systems, UPS Systems, Generator Operation
San Diego, California, United States · Hybrid
$156k–$260k/yr
Where Ambition Meets Innovation Build a career that matches all your initiative with an impressive dose of innovation. From cutting-edge resources and a collaborative environment to the freedom to make an impact and more…
Skills: Cloud-Native Architecture, API Design, Data Integration, React, Angular
San Diego, California, United States · On-site
The Aircraft Worker performs pre/post-operational checks, fueling and operation of aircraft & support equipment, to include conditional/scheduled inspections and periodic maintenance. Essential Responsibilities: Performs…
Skills: Aircraft Maintenance, Fueling And Defueling, Ground Support Equipment Operation, Corrosion Control, Hazardous Materials Handling
San Diego, California, United States · On-site
$217k–$325k/yr
Job Description The Vertex Biology team in San Diego seeks a strategic and innovative scientific and people leader to help advance therapies for serious diseases. As an ONSITE leader at our cutting-edge San Diego researc…
Skills: Molecular Biology, Cellular Biology, Pharmacology, Physiology, Translational Research
San Diego, California, United States · Hybrid
$131k–$140k/yr
Senior Process Engineer, Assay Development Location: San Diego, CA Job Type: Full-Time Compensation: $131,000 - $140,000 About Us We are a venture-backed, stealth-stage biotechnology company based in San Diego, focused o…
Skills: NGS Library Preparation, Process Engineering, Automation Protocol Development, Design of Experiments (DOE), Statistical Process Control (SPC)
San Diego, California, United States · On-site
Product and Manufacturing Test Engineering Manager (Accenture LLP; San Diego, CA): Accenture LLP has multiple openings for the position of Product and Manufacturing Test Engineering Manager in San Diego, CA, and the job …
Skills: System-level Validation, Embedded Technology, Consumer Technology Platforms, Regression Testing, Defect Investigation
San Diego, California, United States · On-site
$117k–$175k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > Graphics Software Engineering General Summary: Interested in enabling next generation graphics, games, ray tracing, machine learning, im…
Skills: C++, C, GPU Hardware, Graphics Concepts, Vulkan
San Diego, California, United States · On-site
$180k–$271k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > Packaging Engineering General Summary: The Qualcomm Package Electrical Team has an opening in the areas of signal integrity and power in…
Skills: Signal Integrity, Power Integrity, Package Extraction, System Simulation, DDR Analysis
San Diego, California, United States · On-site
$140k–$210k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > ASICS Engineering General Summary: As a leading technology innovator, Qualcomm pushes the boundaries of what's possible to enable next-g…
Skills: ASIC Design, RTL Design, FPGA Design, SoC Architecture, Machine Learning IPs
San Diego, California, United States · On-site
$179k–$269k/yr
Company:Qualcomm Technologies, Inc. Job Area:Operations Group, Operations Group > Product Management General Summary: Key Responsibilities Develop product requirements based on customer feedback, competitive analysis, in…
Skills: Product Management, AI Software Stacks, LLM Optimization, Kubernetes, Cloud-Native Infrastructure
San Diego, California, United States · On-site
$142k–$212k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > Camera Software Engineering General Summary: Took a fantastic photo or video of your favorite subject using your smartphone and wondered…
Skills: C, C++, Python, Camera ISP, Embedded Systems
San Diego, California, United States · On-site
$118k–$176k/yr
RELOCATION ASSISTANCE: No relocation assistance available CLEARANCE REQUIRED FOR START: No CLEARANCE TYPE: Secret TRAVEL: NoDescription At Northrop Grumman, our employees have incredible opportunities to work on revoluti…
Skills: Cost Control Analysis, Earned Value Management, Financial Forecasting, Budget Preparation, Variance Analysis
San Diego, California, United States · On-site
$22/hr–$34/hr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Services Group, Engineering Services Group > Engineering Technician General Summary: As an Engineering Technician, you will frequently collaborate with Engineers a…
Skills: Equipment Configuration, Troubleshooting, Circuit Testing, KPI Documentation, Inventory Tracking
San Diego, California, United States · On-site
$158k–$238k/yr
Company:Qualcomm Technologies, Inc. Job Area:Engineering Group, Engineering Group > Machine Learning Engineering General Summary: As part of the AISW engineering team at Qualcomm, you will be the software system integrat…
Skills: Python, PyTest, C/C++, CI/CD, ML Inference Frameworks
San Diego, California, United States · On-site
$180k–$250k/yr
Overview Director - UG Transmission Engineering – (San Diego, CA) At NV5, we understand the aging electrical grid faces significant challenges. The need for resiliency to withstand harsher weather while meeting increasin…
Skills: Underground Transmission Design, Project Management, Leadership, Technical Proposal Writing, QA/QC
San Diego, California, United States • Hybrid
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
Lead the analytical verification and validation strategy for laboratory-developed tests (LDTs) under design control. This includes designing performance studies, authoring quality documentation, and collaborating cross-functionally from design input through product launch.
Requires a PhD with 10+ years or a BS/MS with 15+ years of industry experience in molecular biology or biotechnology. Must have demonstrated expertise in advancing LDTs through validation in regulated clinical environments like CLIA or CAP.
Location: San Diego, CA
Job Type: Full-Time
Salary: $175,000 - $190,000
We are seeking a Senior Staff Scientist to provide technical leadership for assay development under design control, with primary responsibility for analytical verification and validation of laboratory-developed tests (LDTs). This role will set validation strategy, translate product and clinical requirements into rigorous study plans and acceptance criteria, and ensure high-quality execution and documentation in a regulated environment.
The successful candidate will combine strategic scientific leadership with a willingness to perform hands-on laboratory work. The role partners closely with R&D, Product Management, Clinical, Lab Operations, Bioinformatics, Software, Quality, and Regulatory throughout the product development lifecycle, from design inputs through launch and post-launch improvements.
Own or co-own design verification and analytical validation strategy for assigned assays, including study design, sample and replicate plans, acceptance criteria, statistical approach, execution, data interpretation, and final reports.
Design and lead analytical performance studies, as applicable, including accuracy, precision and reproducibility, analytical sensitivity and specificity, limit of detection, linearity or reportable range, interference, carryover, contamination risk, stability, robustness, and method or instrument equivalency.
Partner with Product Management, Clinical, and Regulatory to translate intended use, product requirements, and clinical needs into clear, testable design inputs and verification or validation methods.
Maintain traceability among user needs, design inputs, design outputs, risk controls, test methods, protocols, results, and design changes.
Perform and/or directly supervise hands-on laboratory work for critical experiments, method troubleshooting, and analytical validation studies.
Author and review high-quality development and quality documentation, including study plans, protocols, reports, SOPs, work instructions, technical assessments, deviations, investigations, and change-control records.
Communicate technical risks, tradeoffs, recommendations, and decisions clearly to cross-functional stakeholders and company leadership.
Mentor junior scientists and establish high standards for experimental design, data integrity, documentation quality, and scientific communication.
Required:
Degree in Molecular Biology, Biochemistry, Biotechnology, or related discipline.
PhD with 10+ years of relevant industry experience or BS/MS with 15+ years of relevant industry experience.
Demonstrated experience advancing LDT products from development through analytical validation, transfer, and launch.
Substantial hands-on experience designing, executing, analyzing, and documenting analytical verification and validation studies for LDTs.
Strong working knowledge of design controls, risk management, cGMP principles, and ISO 13485-aligned quality systems.
Experience working in a regulated clinical laboratory and/or diagnostic product-development environment, such as CLIA, CAP, or New York State-regulated laboratories.
Proven ability to generate and critically review high-quality technical and quality documentation suitable for audits, inspections, and regulatory review.
Demonstrated ability to lead complex cross-functional initiatives and influence scientific, engineering, operational, quality, and regulatory stakeholders without direct authority.
Strong scientific judgment, structured problem-solving skills, and clear written and verbal communication.
Willingness and ability to perform hands-on laboratory work as program needs require.
Demonstrated commitment to mentoring and developing scientists.
Preferred:
Experience with high-complexity NGS assays.
Experience supporting regulatory interactions, submissions, or reimbursement evidence packages, including MolDX, in partnership with Quality and Regulatory.
Experience with automated or high-throughput assay workflows and transfer into regulated clinical laboratory operations.
Familiarity with CLSI guidance and statistical methods used in analytical performance evaluation.
A center for entrepreneurial innovation at the intersection of AI and data science
Foresite Labs creates companies at the intersection of AI/machine learning and science. We believe AI, generative AI, and data science—when applied with scientific rigor—can accelerate discovery and drive innovations that benefit humanity. We provide the foundation for bold ideas to take shape and accelerate, shaping a better future for all. We offer competitive salaries, excellent benefits, and a flexible work environment where employees learn from top thinkers across multiple disciplines. With headquarters in San Francisco and Boston, we’re building a culture where scientific rigor meets entrepreneurial ambition. Foresite Labs Values Truth over progression: We follow the science, pursuing ideas that are grounded in data and abandoning them when not supported by the evidence. Take good risks: Our culture values informed risk-taking: good decisions are celebrated even when they result in bad outcomes. Everyone feels safe to contribute ideas and to learn from failure. Single accountable person: The project team lead is accountable for all decisions and for maintaining transparency and information flow within the team; we trust the project teams. The Review Committee unlocks capital and sets directions. Simplicity and Focus: “Companies die from indigestion, not starvation” (Bill Hewlett) We will focus on a few ideas aggressively and minimize all other distractions. Everyone will have a few key goals that have measurable outcomes. Respect and Community: Our employees are our greatest asset; everyone invests in creating an environment of collaboration and respect. We support their careers and career development whether they stay, go to a Labs company, or end up somewhere else.
Offices: 601 California St, Suite 600, San Francisco, California 94108, US · 625 Massachusetts Ave, 2nd Floor, Cambridge, MA 02139, US
Based on 2578 listings with disclosed salaries, most engineering jobs in San Diego, CA pay between $79k–$210k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 2,986 open engineering positions in San Diego, CA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Qualcomm, Northrop Grumman, Northrop Grumman Mission Systems, Inc., Apple, Solar Turbines, among others. Browse the listings above to see every active employer.
Yes — 565 of the 2986 open engineering positions offer remote or hybrid work (100 remote, 465 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
