San Diego, California, United States · On-site
$158k–$294k/yr
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more t…
Skills: Nanoparticle Formulation, LNP Delivery Systems, Analytical Characterization, Non-viral Gene Transfer, Data Analysis
San Diego, California, United States · On-site
$60k–$80k/yr
Certified Labs- Outside Sales Representative Territory: San Diego, CA About the Role We are looking for a high-energy, disciplined Sales Representative to own a territory and drive lubrication excellence for industrial p…
Skills: Field Sales, Account Management, Consultative Selling, Technical Presentations, Salesforce
San Diego, California, United States · On-site
$65k–$108k/yr
The Company Dexcom Corporation (NASDAQ DXCM) is a pioneer and global leader in continuous glucose monitoring (CGM). Dexcom began as a small company with a big dream: To forever change how diabetes is managed. To unlock i…
Skills: System Testing, Test Planning, Defect Management, Risk Assessment, Test Script Execution
San Diego, California, United States · Remote OK
$112k–$137k/yr
SOLV Energy is a leading provider of infrastructure services to the power industry, designing, building and maintaining utility scale solar, battery storage and high voltage substation projects nationwide. Job Descriptio…
Skills: Contract Negotiation, Risk Mitigation, EPC Contracts, Renewable Energy Knowledge, Leadership
San Diego, California, United States · On-site
$129k–$194k/yr
RELOCATION ASSISTANCE: Relocation assistance may be available CLEARANCE REQUIRED FOR START: Yes CLEARANCE TYPE: Secret TRAVEL: Yes, 10% of the TimeDescription At Northrop Grumman, our employees have incredible opportunit…
Skills: Network Design, Network Architecture, IPv4/IPv6, BGP, OSPF
San Diego, California, United States · On-site
$161k–$242k/yr
RELOCATION ASSISTANCE: Relocation assistance may be available CLEARANCE REQUIRED FOR START: No CLEARANCE TYPE: None TRAVEL: Yes, 10% of the TimeDescription At Northrop Grumman, our employees have incredible opportunities…
Skills: Program Management, Project Management, Earned Value Management, Risk Management, Budgeting
San Diego, California, United States · On-site
$93k–$148k/yr
RELOCATION ASSISTANCE: Relocation assistance may be available CLEARANCE REQUIRED FOR START: Yes CLEARANCE TYPE: Secret TRAVEL: Yes, 10% of the TimeDescription At Northrop Grumman, our employees have incredible opportunit…
Skills: Requirements Management, Verification and Validation, Interface Control Documents, DOORS, Systems Engineering
San Diego, California, United States · On-site
$70k–$80k/yr
The Team and the Role INDUS is a 100% employee-owned, customer-focused government services provider with expertise in Engineering, Information Technology, Cybersecurity, Program/Financial Management, Logistics, and Data …
Skills: Program Management, Acquisition Management, Data Analysis, MS PowerPoint, MS Excel
San Diego, California, United States · On-site
$43k–$72k/yr
RELOCATION ASSISTANCE: No relocation assistance available CLEARANCE REQUIRED FOR START: No CLEARANCE TYPE: None TRAVEL: NoDescription At Northrop Grumman, our employees have incredible opportunities to work on revolution…
Skills: Composite Layup, Bonding, Tooling Preparation, Blueprint Reading, Shop Arithmetic
San Diego, California, United States · On-site
$193k–$290k/yr
RELOCATION ASSISTANCE: Relocation assistance may be available CLEARANCE REQUIRED FOR START: Yes CLEARANCE TYPE: Secret TRAVEL: Yes, 10% of the TimeDescription At Northrop Grumman, our employees have incredible opportunit…
Skills: People Leadership, Systems Engineering, Workforce Planning, Technical Oversight, MBSE
San Diego, California, United States · On-site
$143k–$179k/yr
Are you passionate about building solutions that will propel Resmed’s Digital Healthcare products into the next decade? Do you want to help shape a platform that is reimagining connected healthcare? Are you experienced i…
Skills: Java, React, Kubernetes, Microservices, Micro-frontends
San Diego, California, United States · On-site
$111k–$151k/yr
Who We Are: Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-chan…
Skills: Analytical Method Development, Antibody Biologics, SEC-UPLC, RP-UPLC, HILIC-UPLC
Los Angeles, California, United States · On-site
$18/hr–$45/hr
Electrician About the Position As Power Design continues to lead the way in innovative energy solutions, we're looking for skilled Electricians to join our growing Energy Team. In this role, you'll work alongside experie…
Skills: Electrical Installation, EV Charging Infrastructure, Solar Energy Systems, Blueprint Reading, NEC Compliance
Los Angeles, California, United States · On-site
$18/hr–$45/hr
Electrician About the Position As Power Design continues to lead the way in innovative energy solutions, we're looking for skilled Electricians to join our growing Energy Team. In this role, you'll work alongside experie…
Skills: Electrical Installation, EV Charging Infrastructure, Solar Energy Systems, Blueprint Reading, NEC Compliance
Mountain View, California, United States · On-site
Logos Space is a Low Earth Orbit (LEO) satellite system purpose-built to serve the connectivity needs of the commercial enterprise users and government users. We will help fill an important gap in the market, providing r…
Skills: Waveform Design, Protocol Stack Design, Modem Engineering, System Integration, Subsystem Testing
San Diego, California, United States · Remote OK
$68k–$113k/yr
Overview Waters Corporation's Field Services Organization is comprised of highly skilled, motivated and customer focused professional that are technical experts on Waters’ product suite. As a Regional Service Manager wor…
Skills: Team Management, Recruiting, Customer Satisfaction, Technical Support, Sales
San Diego, California, United States · On-site
$28/hr–$52/hr
<h1><span style="mso-fareast-font-family: 'Times New Roman';">About Quartus</span></h1><p class="MsoNormal" style="margin-bottom: 7.5pt; background: white;"><span style="mso-fareast-font-family: 'Times New Roman'; mso-bi…
Skills: CNC Machining, Manual Machining, Tooling Development, Fixture Development, 3 Axis CNC Mill
San Diego, California, United States · Remote Solely
$123k–$141k/yr
Senior UX Design Specialist (Virtual) Company: Tapestry - KTN Tapestry Solutions, A Boeing Company, brings over 30 years of industry experience designing, implementing, training, and supporting high-quality, cost-effecti…
Skills: UX Design, Figma, User Research, Interaction Design, Wireframing
San Diego, California, United States · On-site
$28/hr–$30/hr
Supports the testing and basic troubleshooting of computer systems and software. Position also includes writing test procedures and reports, some domestic travel (1-2 weeks per year), occasional 2nd or 3rd shift testing,…
Skills: Software Testing, Hardware Testing, Troubleshooting, Technical Reporting, Windows OS
San Diego, California, United States · On-site
$73k–$94k/yr
JLL empowers you to shape a brighter way. Our people at JLL are shaping the future of real estate for a better world by combining world class services, advisory and technology for our clients. We are committed to hiring …
Skills: Electrical Installation, Electrical Maintenance, Troubleshooting, VFDs, UPS
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Lead research efforts for nanoparticle formulation and analytical characterization to develop novel non-viral drug delivery vehicles. Collaborate across cross-functional teams to advance platform and pipeline programs from concept through clinical validation.
Requires a Ph.D. in chemistry, engineering, or a related field with over 10 years of experience and a proven track record of advancing candidates to IND-enabling studies. Expertise in LNP delivery systems and nanoparticle science is essential.
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech!
The newly formed Genetic Medicine Technology group in gRED (Genentech Research and Early Development) is redefining the future of cell and gene therapies. Our proprietary non-viral gene delivery and gene editing platforms, including lipid nanoparticles (LNPs), piggyBac® and Cas-CLOVER™ technologies, enable the development of next-generation CAR-T therapies with the potential to cure cancer and genetic diseases.
We are seeking a highly motivated leader with a strong technical background in nanoparticle and LNP-mediated nucleic acids drug delivery. This person will join a dynamic and talented research team advancing non-viral therapies. This individual will direct efforts in developing novel non-viral drug delivery vehicles by overseeing the nanoparticle/nanotechnology function, working closely with the head of GMT. This individual will collaborate directly with gene editing, genomics, and molecular biology functions at Genentech San Diego to advance both platform and pipeline programs. This individual will also collaborate broadly with Genentech San Francisco and Roche research and innovation sites, including oncology and immunology therapeutic disease areas. The ideal candidate will have deep technical expertise with LNPs and chemistry, with additional expertise in pre-clinical models, xenographs, and immune cell biology/manipulation.
Lead all research efforts for nanoparticle formulation, analytical characterization, and primary functional evaluation in the Genetic Medicines Technology group.
Discover and optimize applications of novel lipids from diverse structural families for LNP-mediated delivery of nucleic acid payloads.
Co-lead screening efforts, in vitro and in vivo, working closely with molecular and in vivo pharmacology groups, to identify novel LNP formulations for optimal tissue/cell delivery.
Collaborate with diverse groups across the organization, including those representing cell therapy, vector engineering, pharmacology, translational biology, immuno-oncology, CMC, process development, and small molecule subject matter experts.
Study fundamental mechanisms of action including LNP circulation, cellular uptake, endosomal escape, and specific behaviors unique to a particular payload class.
Lead efforts to advance platform development for an in vivo therapeutic application of an LNP modality from concept through clinical validation.
Analyze and interpret complex datasets, prepare clear reports, and present findings in internal program meetings, cross-functional reviews, and governance forums.
Lead and contribute to external publications, conference abstracts, and patent filings relevant to LNP development for autoimmune, neurology, and oncology indications.
Ph.D. in chemistry, engineering, bioengineering, nanotechnology, material science or a related field with 10+ years of relevant industry and academic experience.
Experience successfully advancing a candidate to IND-enabling studies is required.
Proven expertise in nanoparticle science, especially LNP delivery systems and non-viral gene transfer/delivery.
Strong data analysis skills and familiarity with design of experiments statistical analyses for process optimization, using software such as JMP statistical tools.
Excellent communication, organizational, and leadership skills.
Preferred, but not required background:
A strong background in DNA delivery is a plus.
Familiarity with nucleic acids chemistry and molecular biology is highly desirable.
A background working with targeted siRNAs, liposomes, or ADCs is valued.
Experience working in the immunology space and with T cells is a plus, though not required.
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of San Diego, CA is $158,200 to $293,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology & Life Sciences Industry ten years in a row by the Dow Jones Sustainability Indices (DJSI). For more information, please visit https://careers.roche.com Read our community guidelines here: https://www.roche.com/some-guidelines.htm #Roche #Biotechnology #Pharmaceuticals #Diagnostics #Healthcare #PersonalisedHealthcare #GreatPlaceToWork #Innovation
Offices: Grenzacherstrasse, Switzerland 🇨🇭 , 4070, CH · 4414 Lake Boone Trail, Raleigh, NC 27607, US · 7070 Mississauga Rd, Mississauga, ON L5N 5M8, CA · Calle Dionisio Derteano 144, San Isidro, Lima 15047, PE · 333 Buckhead Ave NE, Atlanta, GA 30305, US
Based on 2631 listings with disclosed salaries, most engineering jobs in San Diego, CA pay between $79k–$211k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 3,048 open engineering positions in San Diego, CA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Qualcomm, Northrop Grumman, Northrop Grumman Mission Systems, Inc., Apple, Solar Turbines, among others. Browse the listings above to see every active employer.
Yes — 584 of the 3048 open engineering positions offer remote or hybrid work (105 remote, 479 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
