Jobs in Philadelphia, PA (Now Hiring) — 9,932 open at 1,774 companies — Page 345
RhyGaze AG
(Associate) Director, CMC Analytical Development
Philadelphia, Pennsylvania, United States · Hybrid
Senior+
<p>RhyGaze is a biotech company developing transformative gene therapies to restore vision in patients with blindness. Our programs target patients with blinding retinal diseases, and we are committed to bringing life-ch…
Philadelphia, Pennsylvania, United States · On-site
Mid level
Temple University's College of Education - Institute on Disabilities is searching for a Part Time Health Equity Coordinator. Salary Grade: T24 Position Summary: At the Institute on Disabilities’ Health Equity Program in …
Skills: Disability And Health Equity, Written Communication, Verbal Communication, Project Management, Community Engagement
Philadelphia, Pennsylvania, United States · On-site
Mid level
About Shamrock Trading Corporation RTS is part of Shamrock Trading Corporation, a family of brands that has been serving the transportation and logistics industries since 1986. Shamrock offers factoring solutions, export…
Skills: Sales, Business development, Client retention, Relationship building, Cold calling
Philadelphia, Pennsylvania, United States · Hybrid
Mid level$100M raised
Overview Being good neighbors – helping people, investing in our communities, and making the world a better place – is who we are at State Farm. It is at the core of how we operate and the reason for our succ…
Skills: Auto collision repair, Auto damage estimating, Customer service, Critical thinking, Decision-making
Philadelphia, Pennsylvania, United States · On-site
$60k–$65k/yr
Mid level$250M raised
Job Title: Warehouse Manager Location: PHL Airport Compensation: $60,000 - $65,000 Reports to: Senior Management Who We Are On the Go has elevated the dining and retail experience for travelers by bringing together world…
Skills: Inventory Management, Purchasing, Logistics, Product Receiving, Cost Control
Philadelphia, Pennsylvania, United States · On-site
$18/hr–$20/hr
Mid level$20K raised
Greater Philadelphia YMCA Employment Opportunity! Do you love connecting with people and sharing your passion with others? We are looking for our Aquatic Supervisor to join our team at the Y! We spend our days positively…
Skills: Leadership, Staff Supervision, Member Service, Pool Maintenance, Water Quality Testing
Philadelphia, Pennsylvania, United States · On-site
Mid level$12M raised
AdvanSix plays a critical role in global supply chains, innovating and delivering essential products for our customers in a wide variety of end markets and applications that touch people’s lives, such as building a…
Remote Customer Support Representative / Live Chat Agent
Philadelphia, Pennsylvania, United States · Remote OK
$27/hr–$40/hr
Mid level$8M raised
Remote Customer Support Representative / Live Chat Agent Job Overview Audacy, a leading digital media company specialising in audio entertainment, is seeking a dedicated and professional Remote Customer Support Represent…
Skills: Live Chat Support, Customer Relationship Management (CRM), Written Communication, Technical Troubleshooting, Problem Solving
Philadelphia, Pennsylvania, United States · On-site
Entry level$134M raised
Description Backed by Callaway Golf and Danny Meyer’s Enlightened Hospitality Investments, Five Iron blends world-class technology with hospitality-driven service across its sports bars, restaurants, and entertainment ve…
Philadelphia, Pennsylvania, United States · Remote OK
Entry level
Description The GREAT STATE TEAM is seeking Remote Health Care Customer Service Representatives to join our fast-growing teams! As a Health Care Customer Service Representative, you will be handling inbound and outbound …
Philadelphia, Pennsylvania, United States · On-site
Senior
Description Pennbrook Apartments is seeking experienced Lead Maintenance Supervisors to oversee maintenance operations at our apartment communities in Philadelphia, PA. The ideal candidates will have strong troubleshooti…
Skills: HVAC Troubleshooting, Plumbing, Electrical Systems, Unit Turns, Team Leadership
Philadelphia, Pennsylvania, United States · On-site
Mid level
Description Pennbrook Apartments is seeking an experienced and motivated Property Manager to oversee and lead the daily operations of our apartment community in the Philadelphia area. The ideal candidate is a strong lead…
Philadelphia, Pennsylvania, United States · On-site
$20/hr
Entry level
About Us: At Body + Beauty Lab, we pride ourselves on creating a warm and welcoming environment for both our clients and our team. We believe that a positive and supportive culture is essential to providing exceptional c…
Skills: Appointment Scheduling, Customer Service, Point of Sale Transactions, Client Education, Sales Performance
Philadelphia, Pennsylvania, United States · Hybrid
Entry level
Overview Opportunity: Human Resources Coordinator We are seeking a detail-oriented, team player who will perform administrative tasks to support various aspects of compensation, HRIS programs, onboarding, and hotel acqui…
Skills: HRIS, Microsoft Excel, Data Reporting, Compensation Analysis, Onboarding
Philadelphia, Pennsylvania, United States · On-site
$15/hr–$19/hr
Entry level$4.0B raised
We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate…
Skills: Customer Service, Cashier Duties, Inventory Management, Teamwork, Communication
Philadelphia, Pennsylvania, United States · Remote OK
Entry level
Join Our Team at Duncan Solutions, LLC Duncan Solutions, LLC, is a full-service transportation management company that focuses on connecting people, technology, and data to make cities more livable and efficient. As a le…
Patient Care Technician Emergency Dept FT 40hrs Days Flex 7a-3:30p
Philadelphia, Pennsylvania, United States · On-site
Entry level
Provides direct and indirect patient care duties under the guidance and direction of the registered nurse. Responsible for implementing components of the plan of care through the initiation/completion of procedures relat…
Skills: Patient Care, Vital Signs Measurement, ECG Performance, Venipuncture, IV Placement
Philadelphia, Pennsylvania, United States · On-site
Mid level
Under the direction of Registered Nurses completes portion of the patient assessment. Provides patient care, assesses units for safety and maintains complete and accurate documentation. Leads and co-leads therapeutic act…
Skills: Patient Care, Assessment, Documentation, Therapeutic Activities, Safety
Research Postdoctoral Fellow - Bhagwat Laboratory - Acute Myeloid Leukemia
Philadelphia, Pennsylvania, United States · On-site
$21k–$110k/yr
Mid level
SHIFT: Day (United States of America) Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspi…
Skills: Independent Scholarly Research, Project Planning, Data Interpretation, Grant Writing, Manuscript Writing
Philadelphia, Pennsylvania, United States · On-site
$18/hr–$18/hr
Mid level
Job DetailsJob Location: 1007WLEHIG - Philadelphia, PA 19133Salary Range: $18.00 - $18.00 HourlySummary of Position: Assists the clinical staff with the daily tasks to include ensuring the safety and welfare of all consu…
Skills: Empathy, Clinical Documentation, Time Management, Organizational Skills, Oral Communication
(Associate) Director, CMC Analytical Development
RhyGaze AG
Philadelphia, Pennsylvania, United States • Hybrid
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Full-time
postgraduate degree
Opportunity To Develop Breakthrough Therapies, Collaborative And Entrepreneurial Culture
Posted 32d ago
~40 hrs/week
Responsibilities
Oversee outsourced analytical activities and manage CDMOs to ensure scientific rigor and regulatory compliance for gene therapy programs. Lead the development, validation, and transfer of analytical methods while supporting regulatory filings such as INDs and BLAs.
Requirements
Requires an advanced degree in a scientific field and at least 10 years of direct experience in gene therapy product development. Must have a proven track record of managing external laboratories and authoring regulatory documents for clinical phases.
Full job description
RhyGaze is a biotech company developing transformative gene therapies to restore vision in patients with blindness. Our programs target patients with blinding retinal diseases, and we are committed to bringing life-changing treatments to those in need.
We are seeking an experienced and highly motivated Associate Director/Director of Analytical Development to join our Chemistry, Manufacturing and Controls (CMC) organization. This role will be responsible for overseeing outsourced analytical activities performed by external Contract Development and Manufacturing Organizations (CDMOs) and analytical partners across early-stage development programs.
The ideal candidate brings strong expertise in analytical method qualification, validation, transfer, and lifecycle management for gene therapy products, including gene editing-, adeno-associated virus (AAV)-, and/or lipid nanoparticle (LNP)-based modalities. This individual will serve as the analytical CMC lead across external networks, ensuring scientific rigor, operational excellence, and regulatory compliance while acting as a key crossfunctional partner internally and externally. The successful candidate will thrive in a fastpaced biotech environment and demonstrate a collaborative, committed, and pragmatic
mindset.
Tasks
Lead and oversee external analytical development within the CMC organization for gene therapy programs.
Manage analytical activities performed at CDMOs and external testing laboratories, ensuring timelines, quality, and scientific standards are achieved.
Provide scientific oversight for analytical method development, qualification, validation, transfer, and troubleshooting activities.
Support analytical strategies for drug substance and drug product development from early clinical stages through late-phase development.
Create and approve Certificate and Analysis for sponsor owned Drug Substance, Drug Product, and Starting Materials.
Author, review and approve analytical protocols, reports, specifications, method validation packages, and stability data generated by external partners.
Drive analytical readiness for regulatory submissions including IND, IMPD, BLA, and MAA filings.
Collaborate closely with Manufacturing, Quality, Regulatory Affairs, and external partners to ensure alignment of CMC objectives.
Support analytical investigations, deviations, OOS/OOT assessments, comparability studies, and change controls.
Contribute to selection, onboarding, governance, and performance management of CDMOs and analytical service providers.
Ensure all outsourced analytical activities comply with GMP and applicable regulatory expectations.
Act as the internal analytical SME for modalities including AAV, DNA, RNA and LNPs
Requirements
Education & Experience
Advanced degree in Analytical Chemistry, Biochemistry, Biotechnology, Molecular Biology, Pharmaceutical Sciences, or related field (MS/PhD preferred).
At least 10 years of direct hands-on experience with gene therapy product development is required.
Experience managing outsourced analytical activities through CDMOs and external laboratories.
Experience supporting drug product development across early and late clinical phases.
Direct experience authoring relevant sections of regulatory documents, including briefing packages, INDs, IMPDs and BLAs, is required.
Knowledge & Skills
Strong expertise in analytical method qualification and validation within regulated GMP environments.
Deep understanding of analytical requirements for gene therapy/gene editing products, including one or more of the following: AAV, DNA, RNA or LNP.
Hands-on scientific mindset with strong attention to detail.
Committed, proactive, and accountable.
Strong communication and stakeholder management skills.
Ability to operate effectively in a fast-paced and evolving biotech environment.
Benefits
Why Join Us
Opportunity to help develop breakthrough therapies for patients with serious vision-threatening diseases.
Work alongside a passionate, highly experienced team at the forefront of ophthalmology innovation.
Meaningful impact in a growing biotech company.
Collaborative, entrepreneurial culture where science and innovation drive decision-making.
We are seeking candidates located in the Philadelphia region, as well as candidates who are willing to travel to and work in Philadelphia for one week each month.
Candidates needs legally able to work in the US (US citizen or US work permit).