San Francisco, California, United States · On-site
ABOUT AARU Aaru operates at the bleeding edge of predictive intelligence, using AI to simulate and predict human behavior at scale. By generating and deploying instances of artificial intelligence that mirror humans, cal…
Skills: Market research, Consumer insights, Research design, Sampling and weighting, Survey methodology
San Francisco, California, United States · On-site
$200k–$350k/yr
About Us Preference Model is building automated ML research engineering. Existing frontier models are brittle when applied to real-world ML tasks. The present bottleneck is the lack of high-quality RL training environmen…
Skills: Machine learning, Reinforcement learning, Large language models, Python, PyTorch
San Francisco, California, United States · Hybrid
$250k–$350k/yr
About Thinking Machines The mission of Thinking Machines is to build AI that extends human will and judgment. We are training frontier models with Inkling, developing Tinker to let people make models their own, and craft…
Skills: Data operations, Vendor management, Project management, Data quality assurance, Process improvement
San Francisco, California, United States · Hybrid
$173k–$234k/yr
We are rebuilding biotech for the AI era. When a breakthrough is delayed, the world waits. Getting a molecule from discovery to patients, or a crop from lab to field, involves thousands of slow, manual, disconnected step…
Skills: Software Engineering, Developer Experience, Platform Engineering, Node.js, Python
San Francisco, California, United States · On-site
$48/hr–$60/hr
Under general supervision of the Clinical Manager and guided by the policiesand procedures of UCSF Medical Center, Ambulatory Services and the Department of Ophthalmology, the Jr. Ophthalmic Photographer is responsible f…
Skills: Ophthalmic photography, Retinal angiography, Ophthalmic testing, Patient care, Clinical technician duties
San Francisco, California, United States · On-site
$87/hr–$122/hr
We are so glad you are interested in joining Sutter Health! Organization: CPMC-California Pacific Med Center Van Ness Position Overview: Delivers pharmaceutical care through the provision of patient-centered clinical ser…
Skills: Pharmaceutical care, Patient assessment, Medication therapy, Clinical pharmacy, Medical terminology
San Francisco, California, United States · On-site
About Us Radical Numerics is an AI research lab building general biological intelligence. Our mission is to master the code of life, and our purpose is to reduce human suffering. Our team created Evo, and started the fie…
Skills: Biodefense, Product Management, Pathogen Genomics, Biosurveillance, Metagenomic Sequencing
San Francisco, California, United States · On-site
About Us Radical Numerics is an AI research lab building general biological intelligence. Our mission is to master the code of life, and our purpose is to reduce human suffering. Our team created Evo, and started the fie…
Skills: Business Development, Strategic Partnerships, Life Sciences, Pharma, Diagnostics
San Francisco, California, United States · On-site
Senior Clinical Research Coordinators independently coordinate and are accountable for the overall administration of one or more clinical studies, typically requiring advanced-level knowledge and skills. They may provide…
Skills: Clinical research coordination, Project management, Regulatory compliance, Financial analysis, Budgeting
San Francisco, California, United States · On-site
$200k–$350k/yr
About Us Preference Model is building automated ML research engineering. Existing frontier models are brittle when applied to real-world ML tasks. The present bottleneck is the lack of high-quality RL training environmen…
Skills: C, C++, CUDA, Python, Reinforcement learning
San Francisco, California, United States · On-site
$106k–$278k/yr
Job Function Summary: Involves developing and utilizing computational tools and systems to analyze and interpret biological or other research data. Utilizes and develops algorithms, computational techniques, and statisti…
Skills: Bioinformatics, Python, SQL, Machine learning, AlphaFold3
San Francisco, California, United States · On-site
$128k–$277k/yr
Involves the establishment and supervision of processes (e.g., performance improvement, clinical documentation, etc.) to achieve the optimal degree of excellence in the services rendered to every patient. Evaluation of p…
Skills: Performance improvement, Clinical documentation, Data collection, Data analysis, Quality improvement
San Francisco, California, United States · Remote OK
$192k–$260k/yr
Employer: Twitch Interactive, Inc. Position: Applied Scientist III - AMZ27946.1 Location: San Francisco, CA Multiple Positions Available: Participate in the design, development, evaluation, deployment and updating of dat…
Skills: Machine learning, Natural language processing, Statistical modeling, Bayesian models, Deep neural networks
San Francisco, California, United States · On-site
$175k–$240k/yr
About us Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biol…
Skills: Python, Full-stack development, Backend engineering, FastAPI, REST APIs
San Francisco, California, United States · Hybrid
The Department of Pharmaceutical Services provides a full range of services for patients cared for by the Medical Center at UCSF and its providers and payors. These services include, but are not limited to: drug procurem…
Skills: Pharmaceutical care, Medication access, Prior authorizations, Medication history, Drug information
San Francisco, California, United States · On-site
$200k–$350k/yr
About Us Preference Model is building automated ML research engineering. Existing frontier models are brittle when applied to real-world ML tasks. The present bottleneck is the lack of high-quality RL training environmen…
Skills: Machine learning, Reinforcement learning, Python, PyTorch, JAX
San Francisco, California, United States · On-site
$90/hr–$121/hr
UCSF Benioff Children's Hospital is recognized throughout the world as a leader in health care, known for innovation, technology and compassionate care. UCSF has one of the top children's hospitals in the nation, accordi…
Skills: Pediatric Critical Care, Patient Care, Clinical Monitoring, Mechanical Ventilation, Tracheostomy Care
San Francisco, California, United States · Hybrid
$280k–$320k/yr
About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of co…
Skills: Applied AI, LLM development, Prompting, Context engineering, Agent architectures
San Francisco, California, United States · On-site
$125k–$250k/yr
About Patronus AI Patronus AI is a frontier lab developing simulation research and infrastructure to accelerate progress toward human-aligned AGI. We are on a mission to simulate all of the world’s intelligence. We are t…
Skills: Reinforcement learning, Simulation design, Task design, Project management, Data analysis
San Francisco, California, United States · Hybrid
$145k–$181k/yr
Welcome to Planet. We believe in using space to help life on Earth. Planet designs, builds, and operates the largest constellation of imaging satellites in history. This constellation delivers an unprecedented dataset of…
Skills: PCB Design, Altium Designer, RF Design, Microwave Design, High-speed Digital Design
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
The Simulation Architect leads the methodological discovery and design of simulations to anchor proofs of concept during the sales process. They serve as the primary authority on accuracy and validation, helping clients understand and defend simulation-based decisions.
Candidates must have 7 or more years of experience in consumer insights or market research with deep quantitative expertise. Strong statistical fluency and the ability to defend complex research methodologies to senior stakeholders are essential.
Aaru operates at the bleeding edge of predictive intelligence, using AI to simulate and predict human behavior at scale. By generating and deploying instances of artificial intelligence that mirror humans, called agents, Aaru simulates entire populations with unprecedented accuracy. Our partners use Aaru to refine strategic positioning, identify and understand high-value audiences, validate concepts and messaging before launch, optimize pricing decisions, and build a continuously richer understanding of their customers through simulation. We provide organizations with invaluable foresight, empowering them to anticipate outcomes and proactively make the right decisions at the right time, every time.
We're a small, dedicated, mission-driven team and we intend to stay that way. We believe the best work happens when exceptionally talented people are given ownership, trust and the space to operate without bureaucratic friction. We work with urgency and intellectual honesty and expect new team members to match our velocity. We seek individuals who thrive at the frontier, who push beyond conventional limits, who bring curiosity and conviction in equal measure, and who want their work to have demonstrable impact in the world. If you're energized by the idea of a small team doing things that feel impossible, let’s build together.
Simulation Architects are the methodological authority in Aaru's sales process. Where a traditional Solutions Engineer proves that software runs, you prove that a simulation is right, and you do it in front of the hardest audience in our market: senior insights and research leaders who have spent careers mastering the methods we are asking them to move beyond.
Your room is not a CTO asking about scalability. It is a Head of Insights asking why a simulated audience should beat the tracker they have run for nine years. You win that room because you have run that tracker. You have designed the sampling frames, built the weighting schemes, defended the confidence intervals, and lived through the quiet degradation of panel quality that the industry rarely says out loud. You can prosecute the case for simulation with the credibility of someone who mastered what came before it, and you can state its limits with the honesty that makes senior buyers trust the rest.
You will lead methodological discovery, design the simulations that anchor our proofs of concept, and stand behind the accuracy and validation frameworks that our customers use to defend their decisions internally. You are the person our buyer points to when their CMO asks how we know this is right.
Own the methodological conversation in the sales process: audience construction, representativeness, response synthesis, calibration, and what confidence in a simulated distribution actually means
Translate ambiguous business questions into well-specified simulation designs, including audience definition, stimulus design, and the evaluation standard a result must meet
Design and interpret proof of concept evaluations, including validation against a prospect's own historical research where available
Prosecute the comparison to traditional methods credibly and fairly: where simulation outperforms trackers, surveys, and panels, where it does not yet, and why
Equip champions to defend simulation-based decisions internally, producing the methodological narratives, validation records, and boundary statements they carry into their own rooms
Partner with Account Executives through the full cycle as the interpretive counterpart to their commercial lead, and with Deployment through handoff so the standard set in the sale is the standard met in delivery
Serve as a structured feedback channel into product and research, translating methodological objections from the field into platform priorities
Contribute to Aaru's public methodological voice: accuracy frameworks, validation publications, and industry conversations
You have 7 or more years in consumer insights or market research with genuine quantitative depth: research design, sampling and weighting, tracker and survey methodology, segmentation, or advanced analytics, at an agency, panel provider, or in-house insights function
You have personally designed and defended research methodology to senior, skeptical stakeholders, and have owned the consequences when a study informed a consequential decision
You are statistically fluent. You can reason about distributions, confidence, bias, and validity in plain language, and you know the difference between directional accuracy and predictive validity without looking it up
You can argue against the methods you built your career on, without flinching and without overclaiming. You have watched response rates fall and panels condition, and you have a view on it
You are energized rather than threatened by AI's arrival in your field, and you would rather define how simulation is judged than defend how research used to be done
You are comfortable representing Aaru in senior client settings, including CMO and C-suite conversations, and can hold credibility against a trained methodologist motivated to find the hole
You are prepared to work fully in person in San Francisco
A computer science degree or professional engineering experience. Technical depth on simulation configuration sits alongside you, not inside you. Your job is judgment, not deployment
Prior sales or solutions engineering experience. We will teach you the deal. We cannot teach a decade of research practice
This role is based in San Francisco. Aaru is an in-person company, working 5 days a week in office. Candidates are expected to be located within the San Francisco metro area or open to relocation.
At Aaru, we take care of our people. In addition to a competitive base salary and equity participation, we offer comprehensive medical, vision, and dental coverage, visa sponsorship and relocation support, and various other benefits and perks.
Rethinking the science of prediction.
Rethinking the science of prediction.
Offices: New York, NY 10013, US
Based on 1377 listings with disclosed salaries, most science & research jobs in San Francisco, CA pay between $101k–$305k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 1,946 open science & research positions in San Francisco, CA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include UCSF Department of Anesthesia and Perioperative Care, OpenAI, Anthropic, Sutter Health, Astranis Space Technologies, among others. Browse the listings above to see every active employer.
Yes — 769 of the 1946 open science & research positions offer remote or hybrid work (129 remote, 640 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
