San Francisco, California, United States · On-site
$150k–$225k/yr
About AfterQuery AfterQuery is an applied research lab curating data solutions for foundation model development. We serve every frontier AI lab with the mission of delivering the best data to power the best models. In do…
Skills: Chemical Engineering, Biomedical Engineering, Biotech, Pharma, Process Design
San Francisco, California, United States · On-site
$155k–$200k/yr
About Sygaldry Sygaldry Technologies is building quantum-accelerated AI servers to exponentially speed up training and inference for AI. By integrating quantum and AI, we're accelerating the path to superintelligence, an…
Skills: Modeling, Simulation, AI hardware, ASTRA-sim, Distributed AI acceleration
BiogenSan Francisco, California, United States · Hybrid
$141k–$188k/yr
About This Role: As a Senior Principal Biostatistician, West Coast Hub (WCH), you will be part of a team working on exciting late-stage nephrology programs or new indications in early development. You will play a key rol…
Skills: Biostatistics, Clinical trial methodology, Statistical analysis, Protocol development, Statistical analysis plan
San Francisco, California, United States · On-site
What We’re Building At Medra, our mission is to use AI, robotics, and biology to accelerate life science research, with the ultimate goal of eradicating disease. We have been quietly building the foundational layers of o…
Skills: Protein purification, Mammalian cell culture, AKTA, FPLC, Analytical UPLC/HPLC
BiogenSan Francisco, California, United States · Hybrid
$209k–$288k/yr
About This Role: As Director of Biostatistics, West Coast Hub (WCH), you will provide statistical leadership and accountability for all biostatistics activities and deliverables for one or more late-stage nephrology clin…
Skills: Biostatistics, Clinical trial methodology, Drug development, Regulatory affairs, Statistical leadership
Epsilon Labs, Inc.San Francisco, California, United States · On-site
About Us We're tackling one of healthcare's most critical challenges in medical imaging and diagnostics. Our company operates at the intersection of cutting-edge AI and clinical practice, building technology that directl…
Skills: Reinforcement Learning, Post-training, Multimodal Machine Learning, PyTorch, JAX
San Francisco, California, United States · Hybrid
$280k–$315k/yr
Location: San Francisco, Thousand Oaks, or Washington, DC Position Summary: The Senior Director, Patient Safety & Pharmacovigilance reports to the Senior Vice President, Global Regulatory Affairs and provides strategic a…
Skills: Pharmacovigilance, Patient safety, Signal detection, Risk management, Benefit-risk assessment
San Francisco, California, United States · On-site
$40/hr–$64/hr
The Clinical Research Coordinator will join the GI Division and responsibilities will include coordination of clinical research studies related liver disease and liver transplantation. The Clinical Research Coordinator w…
Skills: Clinical research coordination, Data management, Protocol management, Regulatory compliance, Database management
San Francisco, California, United States · On-site
$150k–$275k/yr
About AfterQuery AfterQuery is an applied research lab curating data solutions for foundation model development. We serve every frontier AI lab with the mission of delivering the best data to power the best models. In do…
Skills: Quality Control, Data Analysis, Software Engineering, Machine Learning, Data Science
San Francisco, California, United States · On-site
$38/hr–$53/hr
We are so glad you are interested in joining Sutter Health! Organization: CPMC-California Pacific Med Center Davies Position Overview: Integrates knowledge, theory and training to properly execute procedures in assigned …
Skills: Laboratory procedures, Specimen processing, Patient registration, Billing record entry, Automated testing instruments
San Francisco, California, United States · Hybrid
About Roadrunner Venture Studios Roadrunner Venture Studios is the nation's leading platform for founding breakthrough ventures in frontier technology. We partner with scientists, engineers, and entrepreneurs to turn dee…
Skills: Atmospheric Science, Meteorology, Weather Research and Forecasting (WRF), Data Assimilation, Numerical Weather Prediction
Epsilon Labs, Inc.San Francisco, California, United States · On-site
About Us We're tackling one of healthcare's most critical challenges in medical imaging and diagnostics. Our company operates at the intersection of cutting-edge AI and clinical practice, building technology that directl…
Skills: Computer Vision, Machine Learning, Vision Foundation Models, PyTorch, JAX
San Francisco, California, United States · On-site
About Chai Discovery Chai builds the design suite for molecules. We train frontier models that learn the underlying foundations of biochemical structure and interaction, so scientists can move faster and pursue targets t…
Skills: Financial Operations, Financial Modeling, Cash Forecasting, Revenue Recognition, Compliance
San Francisco, California, United States · On-site
$56/hr–$79/hr
We are so glad you are interested in joining Sutter Health! Organization: CPMC-California Pacific Med Center Davies Position Overview: Job Profile Summary Integrates knowledge, theory and practice to properly execute pro…
Skills: Histology procedures, Embedding, Sectioning, Automated staining, Immunohistochemistry
San Francisco, California, United States · On-site
$350k–$475k/yr
About Thinking Machines The mission of Thinking Machines is to build AI that extends human will and judgment. We are training frontier models with Inkling, developing Tinker to let people make models their own, and craft…
Skills: Site reliability engineering, Distributed systems, Cloud infrastructure, Kubernetes, Observability
San Francisco, California, United States · On-site
$350k–$475k/yr
About Thinking Machines The mission of Thinking Machines is to build AI that extends human will and judgment. We are training frontier models with Inkling, developing Tinker to let people make models their own, and craft…
Skills: Site reliability engineering, Python, Go, C++, Linux systems internals
San Francisco, California, United States · Hybrid
$300k–$475k/yr
About Thinking Machines The mission of Thinking Machines is to build AI that extends human will and judgment. We are training frontier models with Inkling, developing Tinker to let people make models their own, and craft…
Skills: Full stack engineering, Software engineering, Frontend development, Backend development, API design
San Francisco, California, United States · On-site
Under the supervision of the UCSF Department of OB/GYN & RS, in collaboration with the Medical Director, and guided by the policies and procedures, rules and regulations, and bylaws of the UCSF Medical Center, some Nursi…
Skills: Obstetrics, Gynecology, Patient Triage, Clinical Care, Chronic Disease Management
San Francisco, California, United States · On-site
Job Summary: The Associate Director provides operational leadership and day-to-day management for the UC Health Data Warehouse (UCHDW), supporting the Director in executing strategies for clinical and research data archi…
Skills: Healthcare data warehousing, Business intelligence, Data architecture, Data governance, Clinical data management
San Francisco, California, United States · Hybrid
$106k–$228k/yr
Applies extensive knowledge of clinical research protocols and processes to design research projects of large scope and high degrees of complexity. Effectively manages multiple projects and makes determinations on feasib…
Skills: Clinical research protocols, Clinical trials, Neuromuscular research, Project management, Regulatory requirements
San Francisco, California, United States • On-site
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Manage client projects and coordinate specialized teams to build high-quality data solutions for frontier AI models. Design dataset specifications and drive high-impact execution from scoping to delivery.
Requires 3+ years of experience in chemical, biomedical, or life-sciences engineering with strong quantitative reasoning skills. Candidates should possess a background in process design or drug development and demonstrate leadership excellence.
AfterQuery is an applied research lab curating data solutions for foundation model development. We serve every frontier AI lab with the mission of delivering the best data to power the best models. In doing so, we can make expertise that once took a lifetime to build available to anyone who needs it.
Our customers are the ones building the foundation models themselves and our work sits directly in the loop of how those systems improve. This is a rare opportunity to join a company at a defining moment in AI. Since raising our $30M Series A at a $300M valuation, AfterQuery has grown well over a $100M revenue run rate. We're based in San Francisco and backed by leading investors including Altos Ventures, BoxGroup, and Y Combinator and angels from Google DeepMind, OpenAI, Anthropic, Meta Superintelligence Labs, and Microsoft AI.
Massive Opportunity: We are one of the fastest-growing YC companies in our batch, and we believe we can become one of the fastest-growing YC companies of all time.
Founding Impact: You will own and architect core infrastructure systems that power our platform from the ground up.
Equity & Growth: Competitive salary and meaningful equity. As we scale, you’ll have the opportunity to shape the engineering organization and lead major technical initiatives.
Strong Team: Our founding team has experience from Citadel Securities, Meta, Google, Silver Lake, and Morgan Stanley — work alongside world-class engineers and researchers.
Project and client management: Work with the world’s leading AI organizations to build next-generation data solutions that push the limits of model capability, while directly driving revenue.
Manage expert teams across domains: Lead and coordinate highly specialized contributors across fields like finance, software engineering, law, and more to create high-quality outputs at scale.
Shape how AI systems are trained: Design dataset specifications that directly influence how frontier models are evaluated and improved. Your taste and judgement will shape what foundation models become.
Drive high-impact execution end-to-end: Own critical projects from idea to delivery. From scoping, executing, iterating, and shipping in a fast-moving, high-stakes environment, you will touch it all.
Gain top tier operational experience: Support the team across a range of operational initiatives that will directly contribute to the future of AfterQuery. You will work across multiple parts of the business in the same week, ranging from building, analyzing, coordinating, and executing where needed most.
3+ years of experience in chemical engineering, biomedical engineering, biotech, pharma, or related process/life-sciences engineering roles at top companies, research labs, or clinical/hospital settings
Background in chemical process design, biomedical devices, drug development, or related life-sciences engineering
Deep understanding of chemistry and biology fundamentals along with quantitative process- and systems-level reasoning
High agency and strong work ethic; comfort defining problems and thriving with minimal direction in ambiguous situations
Demonstrated leadership excellence and strong communication abilities
Genuine passion for AI and an entrepreneurial inclination
Demonstrated competitive success (e.g., patents, publications, board/licensing exams, or top-tier academic/professional achievement)
Python proficiency or experience with simulation and analysis tools (e.g., Aspen Plus, MATLAB, COMSOL, bioinformatics pipelines)
Advanced degree (MS/PhD/MD) in chemical engineering, biomedical engineering, chemistry, or a related field
Experience in the pharma, biotech, or medical-device industry
Familiarity with Claude Code or similar AI-assisted workflows
Experience across multiple engineering or life-sciences domain
Health Insurance: Medical, Vision, Dental
401(k) with Employer Match
Daily Meals: Daily UberEats Stipend
Monthly Wellness Stipend
Commute Covered
We are an equal opportunity employer committed to providing a workplace free from discrimination and harassment. Employment decisions are made without regard to legally protected characteristics under applicable federal, state, or local law.
We comply with applicable pay transparency requirements and provide compensation ranges based on the position, qualifications, experience, and other relevant factors. Reasonable accommodations are available to qualified individuals with disabilities and for sincerely held religious beliefs, as required by law. This job description is intended to describe the general nature and level of work performed and is not an exhaustive list of all duties, responsibilities, qualifications, or working conditions associated with the position. We reserve the right to modify this job description as business needs change.
Applied research lab curating data solutions to accelerate foundation model development. Serving every frontier AI lab.
AfterQuery is an applied research lab curating data solutions to accelerate foundation model development.
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