Capable LabsSan Francisco, California, United States · On-site
$90k–$180k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Organic chemistry, Synthetic chemistry, Route planning, Reaction setup, Purification
San Francisco, California, United States · On-site
The Department of Pharmaceutical Services provides a full range of services for patients cared for by the UCSF Medical Center and its providers and payors. These services include, but are not limited to: drug procurement…
Skills: Medication preparation, Medication distribution, Inventory management, Sterile compounding, Aseptic IV techniques
Capable LabsSan Francisco, California, United States · On-site
$155k–$260k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Therapeutic discovery, Scientific research, Experimental design, Assay development, Drug development
Capable LabsSan Francisco, California, United States · On-site
$110k–$165k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Hardware engineering, Electromechanical design, Fluidics, Prototyping, Laboratory automation
San Francisco, California, United States · Hybrid
Job Summary Involves developing and utilizing computational tools and systems to analyze and interpret biological or other research data. Utilizes and develops algorithms, computational techniques, and standard statistic…
Skills: Bioinformatics, Biostatistics, Python, R, Machine learning
San Francisco, California, United States · On-site
$40/hr–$50/hr
The Department of Pharmaceutical Services provides a full range of services for patients cared for by the UCSF Medical Center and its providers and payors. These services include, but are not limited to: drug procurement…
Skills: Medication preparation, Medication distribution, Inventory management, Sterile compounding, Aseptic IV techniques
Capable LabsSan Francisco, California, United States · On-site
$160k–$235k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: System architecture, Mechanical design, Electrical systems, Fluidics, Controls
San Francisco, California, United States · On-site
$172k–$222k/yr
The Models, Quantum, and Silicon (MQS) Center for Quantum Computing (CQC) is a multi-disciplinary team of scientists, engineers, and technicians, on a mission to develop a fault-tolerant quantum computer. We are looking …
Skills: Python, Java, C++, Quantum computing, Calibration
Capable LabsSan Francisco, California, United States · On-site
$150k–$240k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Machine learning, Biomolecular modeling, Drug discovery, Active learning, Data analysis
Capable LabsSan Francisco, California, United States · On-site
$90k–$120k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Mouse handling, Animal husbandry, Dosing, IP administration, IV administration
Capable LabsSan Francisco, California, United States · On-site
$90k–$180k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: In vivo pharmacology, Mouse handling, Dosing, Sample collection, EEG studies
San Francisco, California, United States · Hybrid
$140k–$450k/yr
The Role Lucid Computing, in partnership with the Research Institutes of Sweden (RISE), is building and operating an adversarial testbed for developing and red-teaming AI compute verification solutions. The premise of th…
Skills: Physical security, Threat modeling, Data center infrastructure, Hardware security, Access control
San Francisco, California, United States · On-site
$160k–$180k/yr
Our Mission and Vision Unlearn exists to transform clinical development by making every trial smarter. We harness data, AI, and digital twins to enable faster, more robust studies that bring life-saving treatments to pat…
Skills: Machine learning, AI agents, Digital twins, Clinical development, Statistics
Capable LabsSan Francisco, California, United States · On-site
$90k–$180k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Peptide synthesis, Solid-phase peptide synthesis, HPLC, Prep HPLC, LC-MS
Capable LabsSan Francisco, California, United States · On-site
$155k–$260k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Cell biology, GPCR pharmacology, Assay development, Molecular biology, Chemical biology
Capable LabsSan Francisco, California, United States · On-site
$155k–$260k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: In vivo pharmacology, Mouse study design, PK/PD analysis, Efficacy testing, Safety assessment
Capable LabsSan Francisco, California, United States · On-site
$155k–$260k/yr
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
Skills: Synthetic organic chemistry, Medicinal chemistry, Peptide chemistry, Route design, Purification
San Francisco, California, United States · On-site
$48/hr–$60/hr
To act as a liaison between the Clinical Laboratory and all hospital and non-hospital sites submitting laboratory specimens. Performs all duties of a HLT I processor and assists in non- supervisory duties as assigned. Su…
Skills: Clinical laboratory, Specimen handling, Inventory management, Workflow monitoring, Training
San Francisco, California, United States · On-site
$230k–$330k/yr
In 2026, we launched Computer, the defining product for the new era of agentic AI. We’ve scaled beyond the millions of people using Perplexity every day for research, shopping, investing and curiosity into a new paradigm…
Skills: Product management, AI systems, Agentic systems, Workflow orchestration, Data analysis
StravaSan Francisco, California, United States · Hybrid
$240k–$260k/yr
About Strava Strava is the app for active people. With over 200 million athletes in more than 185 countries, it’s more than tracking workouts—it’s where people make progress together, from new habits to new personal best…
Skills: Data Science, Causal Inference, Machine Learning, SQL, Python
Capable Labs
San Francisco, California, United States • On-site
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Execute overnight organic synthesis workflows, including reaction setup, purification, and characterization to prepare compounds for testing. Maintain accurate experimental records and provide clear morning handoffs to the day team regarding results and issues.
Requires hands-on synthetic chemistry experience and the ability to work independently on a night-shift schedule. Candidates must demonstrate strong experimental discipline, problem-solving skills, and the ability to maintain rigorous documentation.
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.
We value speed and rigor, coupled with excitement, drive, and a strong work ethic. In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy.
Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better. You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems.
We believe excellent work should be met with meaningful reward, ownership, and trust. Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope.
You will run organic-chemistry workflows on a dedicated night-shift schedule so compounds are ready for characterization, biological testing, or handoff the next day. You will execute solution- and solid-phase chemistry, solve experimental problems independently, maintain complete records, and give the day team a clear account of every result and open issue.
Execute overnight synthesis workflows, including route planning, reaction setup, workup, purification, characterization, and sample preparation.
Run and troubleshoot organic reactions involving functional-group transformations, coupling chemistry, protecting-group strategies, late-stage diversification, and parallel synthesis.
Use solution-phase and solid-phase methods where appropriate, including cleavage, deprotection, crude analysis, purification, and final quality control.
Resolve overnight issues involving low conversion, poor selectivity, side products, decomposition, solubility, purification, recovery, and instrument downtime.
Purify and characterize compounds using analytical HPLC, prep HPLC, LC-MS, NMR, flash chromatography, SFC, and related methods as appropriate.
Prepare compounds for in vitro and in vivo testing and maintain accurate experimental and batch-level quality-control records.
Provide clear morning handoffs covering completed work, results, failures, sample locations, risks, and follow-up actions.
Able and willing to work the designated night-shift schedule reliably and operate independently when needed.
Hands-on synthetic chemistry experience and strong experimental discipline.
Interest in owning overnight chemistry from reaction execution through purification, characterization, documentation, and sample handoff.
A creative, fast, rigorous, and safety-conscious approach to laboratory problem-solving.
Sound judgment when a reaction fails, an instrument is down, data look unusual, or the usual day-team contact is unavailable.
The ability to maintain excellent records and create clean, useful handoffs across night and day teams.
In addition to the posted salary range, we offer generous equity options.
Compensation will depend on the skills, experience, and scope of impact you bring. If your background, experience, or compensation needs fall outside this range, we are still open to a conversation based on the scope and impact you could bring.
$500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.
Healthcare: We offer a broad range of medical, dental, and vision coverage options, with Capable covering 100% of the base policy.
You will also have access to HSA, FSA, and 401K plans.
Healthy dinners with the team are provided daily.
We support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways. Our team is already international, with members from Canada, Pakistan, Germany, Austria, Switzerland, China, India, and the United States.
Our process is fast, transparent, and personal. We care about getting to know the person behind the application.
Initial application
First phone screen
Second phone screen
In-person work trial in San Francisco: designed to give both sides a realistic sense of working together. Get to know the founding team!
Curious but not sure? Apply anyway. It takes 5 minutes, and you do not need to be actively job searching to start a conversation.
Some of the best people do not map perfectly to a job description. If this sounds like a place where you could do important work, we would like to hear from you.
And if someone exceptional comes to mind, send them our way here. We read every referral carefully, and if your referral joins Capable, we’ll send you a thank-you bonus.
Capable is an Equal Opportunity Employer; employment with Capable is governed on the basis of merit, competence and qualifications and will not be influenced in any manner by race, color, religion, gender, national origin/ethnicity, veteran status, disability status, age, sexual orientation, gender identity, marital status, mental or physical disability or any other legally protected status.
Based on 1377 listings with disclosed salaries, most science & research jobs in San Francisco, CA pay between $101k–$305k per year. Individual offers vary with seniority, company size, and specialization.
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