San Francisco, California, United States · On-site
$180k–$256k/yr
Senior$551M raised
Your Impact at LILA Lila Sciences is building the infrastructure for autonomous science - AI systems that design experiments, run them in physical labs, and close the loop across life sciences, chemistry, and materials s…
Senior Director, Software Development, Test Automation
San Francisco, California, United States · On-site
$260k–$390k/yr
Senior+$551M raised
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Principal Engineer, Software (Enterprise Platform)
San Francisco, California, United States · On-site
$204k–$310k/yr
Senior+$551M raised
Your Impact at LILA Lila Sciences is building the infrastructure for autonomous science — AI systems that design experiments, run them in physical labs, and close the loop across life sciences, chemistry, and materials s…
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Mid levelVisa sponsorship
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San Francisco, California, United States · Remote OK
Entry level
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San Francisco, California, United States · On-site
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Senior
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San Francisco, California, United States · On-site
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If you have a Candidate Login already, but have forgotten your password please use the steps to reset your password. If you have forgotten your email login, please contact [email protected] subject Workday Candi…
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Capable Labs
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San Francisco, California, United States · On-site
$155k–$260k/yr
SeniorVisa sponsorship
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San Francisco, California, United States · On-site
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Capable Labs
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San Francisco, California, United States · On-site
Senior
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Spring 2027 Science Externship – International Program
San Francisco, California, United States · Hybrid
Entry level
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San Francisco, California, United States · On-site
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Capable Labs
In Vivo Research Technician
San Francisco, California, United States · On-site
$90k–$120k/yr
Mid levelVisa sponsorship
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Staff Pharmacist II - Investigational Drug Service Pharmacist
San Francisco, California, United States · On-site
Mid level
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San Francisco, California, United States · On-site
$155k–$260k/yr
SeniorVisa sponsorship
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San Francisco, California, United States · On-site
$155k–$260k/yr
SeniorVisa sponsorship
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a stron…
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$180k–$256k/yr
Full-time
Medical Insurance, Dental Insurance, Vision Insurance, Employer-paid Life Insurance, Disability Insurance, Flexible Time Off
Posted 10d ago
~40 hrs/week
Responsibilities
Own and develop critical enterprise platform systems focusing on multi-tenancy, authorization, and the developer ecosystem. Build public APIs, SDKs, and integration paths for autonomous agents and internal scientists.
Requirements
Requires 7+ years of backend software engineering experience with strong expertise in API design, multi-tenancy, and cloud infrastructure. Proficiency in Python, FastAPI, Kubernetes, and AWS is essential.
Full job description
Your Impact at LILA
Lila Sciences is building the infrastructure for autonomous science - AI systems that design experiments, run them in physical labs, and close the loop across life sciences, chemistry, and materials science. Our platform enables this to operate reliably at scale for external customers who require security, auditability, and operational rigor.
We're hiring a Senior Software Engineer II, Enterprise Platform to own critical systems across two areas: the enterprise lifecycle (multi-tenancy, auth, auditability) and the developer ecosystem (public APIs, SDKs, MCP so customers and autonomous agents can interact with Lila's platform) that let customers and developers build on Lila. Our internal scientists across both physical and life sciences are first-class customers of this platform, so you'll build for them as directly as for external developers.
We move fast, ship weekly, and expect engineers who thrive in ambiguity, not ones who wait for requirements to be handed to them. You will own outcomes.
What You'll Be Building
Enterprise infrastructure is foundational to making autonomous science deployable in the real world. The systems built in this role will determine how large organizations safely adopt, govern, and scale AI-driven scientific workflows across teams, data domains, and regulatory environments. You'll help build the platform primitives that make that possible.
Multi-Tenancy & Authorization. Build secure tenant isolation, authentication, authorization, and audit across customer organizations. Implement the access boundaries and isolation guarantees that enterprise and regulated (e.g. GxP, FedRAMP) deployments require. Build resilient backend services in Python/FastAPI. Own schema design for multi-tenant data, tenant-aware query patterns, and operational correctness in a regulated environment.
Tenant Self-Serve & Lifecycle. Build the services behind tenant provisioning, self-serve administration, and the customer onboarding lifecycle. Support billing, pricing, and metering surfaces for enterprise customers.
Public & Agent-Facing APIs. Own and evolve Lila's public APIs (REST, streaming, async) designed for both human developers and autonomous agents as first-class consumers. Ship SDKs and define the tool/function interfaces agents call.
MCP & Agent Integration. Build the integration paths that connect MCPs, agents, and data into the platform.
What You'll Need to Succeed
7+ years of backend software engineering, with meaningful experience in APIs, backend services, or platform infrastructure.
Strong expertise in one or more of: API design and versioning, multi-tenancy, authentication/authorization, or backend services at scale.
Solid in Python (e.g. FastAPI), Kubernetes, AWS, databases.
You care about developer experience — you know what makes APIs easy or painful. You write clear errors and think about backward compatibility.
Ship working code regularly. Debug production issues. Own systems end-to-end.
Work well across teams. You'll have real overlap with infra, data, apps, and science teams. Communicate tradeoffs clearly and make decisions under ambiguity.
Bonus Points For
Built or maintained multi-tenant SaaS platforms with audit, compliance, or isolation requirements (SOC 2, HIPAA, GxP, FedRAMP).
You've worked on platforms serving scientific or laboratory data such as LIMS, ELN, bioinformatics, or related systems, and understand the provenance and traceability requirements associated with scientific workflows.
Shipped public developer platforms, APIs, or SDKs and understand what makes integrations sticky.
Familiarity with MCP, OpenAPI, or OIDC/OAuth 2.0.
Worked on tenant isolation patterns (row-level security, schema per tenant, search-path isolation).
Experience with policy-based authorization (OPA) or externalized authz.
Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
Expected Base Salary Range
$180,000—$256,000 USD
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We’re All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science. We are building the foundation to apply AI to every aspect of the scientific method, enabling scientists to bring forth solutions in human health and sustainability at a pace and scale never experienced before.
How much do Science & Research jobs in San Francisco, CA pay?
Based on 1377 listings with disclosed salaries, most science & research jobs in San Francisco, CA pay between $101k–$305k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in San Francisco, CA right now?
There are currently 1,946 open science & research positions in San Francisco, CA listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in San Francisco, CA?
Companies currently hiring include UCSF Department of Anesthesia and Perioperative Care, OpenAI, Anthropic, Sutter Health, Astranis Space Technologies, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in San Francisco, CA?
Yes — 770 of the 1946 open science & research positions offer remote or hybrid work (129 remote, 641 hybrid).
How do I apply for Science & Research jobs in San Francisco, CA?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.