Research Associate, Microfluidics & Platform Operations
Boston, Massachusetts, United States · On-site
$65k–$107k/yr
Mid level$115M raised
The Role Ampersand is actively seeking a talented Microfluidics Microfabrication Engineer with specialization in droplet microfluidic-based single cell assay development in the field of Antibody Discovery. The role will …
Senior Director, Drug Substance and Process Development
Waltham, Massachusetts, United States · On-site
$245k–$270k/yr
Senior+
Company Overview: Innoviva Specialty Therapeutics, Inc., a subsidiary of Innoviva, Inc., is a biopharmaceutical company focused on developing innovative solutions for patients and healthcare providers in the fields of Cr…
Skills: Drug substance process development, CMC, Small molecule API development, cGMP manufacturing, Technology transfer
Company Description The work we do at Eurofins Professional Scientific Services matters, and so do our employees. At Eurofins PSS, we put a focus on your professional growth. We provide our employees the ability to break…
Skills: LC-MS/MS, Peptide Characterization, Method Development, Workflow Optimization, Data Interpretation
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Springfield, Massachusetts, United States · On-site
$50/hr–$55/hr
Mid level$348M raised
Science 37’s Nursing Solutions Group brings together expert nurses who share a passion for organizing, planning and implementing mobile clinical nurse services to participants in clinical trials. Science 37’s extraordina…
Skills: Clinical Research Nursing, Patient Care, Good Clinical Practice, Mobile Health Delivery, Case Management
Director, Insights and Analytics - US Location: Hybrid schedule (3 days onsite and 2 days remote) for local candidates, remote for candidates outside of MA. COMPANY Thea Pharma Inc. is the newly established US commercial…
About the role You'll be the founding ML engineer who owns our matching algorithms from exploration through production and the data platform that feeds them. You'll design and ship the models that rank OOH inventory agai…
Skills: Machine Learning, Ranking and Matching Models, Python, SQL, BigQuery
The Director, Medical Writing provides strategic and operational leadership for medical writing activities across one or more clinical development programs. This role combines hands-on writing expertise with responsibili…
Skills: Medical Writing, Strategic Leadership, Resource Planning, Regulatory Filings, Clinical Development
Practices according to entity mandatory requirements. Practices according to department expectations. Practices with a Customer Service approach to all activities. Utilizes internal and external resources appropriately. …
Skills: Polysomnography, Medical Equipment Operation, Patient Care, Time Management, Customer Service
Practices according to entity mandatory requirements. Practices according to department expectations. Practices with a Customer Service approach to all activities. Utilizes internal and external resources appropriately. …
Skills: Polysomnography, Medical Equipment Operation, Patient Care, Time Management, Customer Service
Veterinary Technician or Assistant - Avian/Exotics at Angell West - Temporary Position
Waltham, Massachusetts, United States · On-site
$25/hr–$30/hr
Mid level
This is a temporary, full-time position, 10am-8:30pm, 40hrs a week rotating weekends and holidays. This a temporary position with the potential to transition into a regular full-time role. We are looking for an experienc…
Skills: Venipuncture, Iv Catheter Placement, Anesthesia, Gavage Feeding, Medication Administration
Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nerv…
Skills: Global Forecasting, Market Research, Competitive Intelligence, Data Analytics, Strategic Planning
Marlborough, Massachusetts, United States · On-site
$24/hr–$28/hr
Mid level$8.0B raised
Bring more to life. Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Cytiva, one of Danaher’s 15+ operating companies, our work saves lives—and…
Postdoctoral Research Fellow - Molecular Cardiology Research Institute Good Lab
Boston, Massachusetts, United States · On-site
$56k–$70k/yr
Mid level
Postdoctoral Research Fellow in Vascular Physiology Molecular Cardiology Research Institute | Tufts Medical Center The Molecular Cardiology Research Institute at Tufts Medical Center in Boston, invites post-doctoral appl…
Skills: Research Design, Data Collection, Statistical Analysis, Scientific Writing, SPSS
Principal Applied Scientist, Agentic Automated Reasoning Group
Santa Clara, California, United States · On-site
$199k–$309k/yr
Senior+$25B raised
The Agentic Automated Reasoning Group is building the next generation of software verification tools combining advances in artificial intelligence, the computational capacity of the cloud, and our deep expertise in the d…
Position Title: Body Imager Location: Tufts Medical Center, Boston, MA Department: Department of Radiology Position Type: Full-time Academic Rank: Assistant, Associate, or Full Professor (commensurate with experience) Jo…
Position Title: Breast Imaging Radiologist – Diagnostic Radiology Location: Tufts Medical Center, Boston, MA Department: Department of Radiology Position Type: Full-time or Part-Time Academic Rank: Assistant, Associate, …
Skills: Mammography, Breast Ultrasound, Breast MRI, Image-guided Biopsies, Diagnostic Radiology
Overview The Principal Business Intelligence Analyst serves as a strategic analytics partner responsible for transforming complex data into actionable insights that drive commercial performance, operational excellence, a…
Skills: Power BI, SQL, Data Modeling, Stakeholder Management, Business Intelligence
Position Title: Musculoskeletal Radiologist Location: Tufts Medical Center, Boston, MA Department: Department of Radiology Position Type: Full-time Academic Rank: Assistant, Associate, or Full Professor (commensurate wit…
About the Opportunity About the College of Arts, Media and Design We are a vibrant community of creators, designers, technologists, and communicators applying creativity across disciplines and harnessing emerging technol…
Skills: Equipment Management, Customer Service, Media Production, Inventory Management, Collaboration
Research Associate, Microfluidics & Platform Operations
Design, fabricate, and optimize novel microfluidic devices to support ultrahigh-throughput antibody discovery. This includes performing cleanroom manufacturing, conducting experiments on microfluidic platforms, and collaborating with R&D teams to translate requirements into system specifications.
Requirements
Requires a Bachelor's or Master's degree in Physics, Mechanical Engineering, Biomedical Engineering, or a related field. Candidates must have demonstrable expertise in cleanroom microfabrication, CAD design, and experience running droplet microfluidic experiments.
Full job description
The Role
Ampersand is actively seeking a talented Microfluidics Microfabrication Engineer with specialization in droplet microfluidic-based single cell assay development in the field of Antibody Discovery. The role will focus on the development of a variety of novel microfluidic devices to facilitate the discovery of rare antibodies at Ultrahigh-throughput using our proprietary microfluidic instrumentation. Level and title will be matched to the candidate’s depth of experience.
As a vital member of our team, you will be primarily responsible for the design, fabrication, and optimization of microfluidic devices that will drive our microfluidics-based antibody discovery platform. This role offers an exciting opportunity to work in a dynamic, fast-paced, entrepreneurial environment, where you will have the chance to work independently and collaboratively within a highly integrated team. This role will be primarily based on-site, though occasional visits to an external cleanroom facility will be required to microfabricate device masters.
Key Responsibilities
Support the creation, iteration and establishment of novel microfluidic device designs for antibody discovery applications.
Perform cleanroom-based manufacture of multi-layer device masters via mask alignment and UV photolithography.
Develop and optimize PDMS soft lithography device manufacturing methods to improve device yield
Fabricate microfluidic devices, maintain and document device stock levels, and perform device quality control characterizations, providing detailed reports which inform decision making and continuous improvement.
Conduct experiments by operating microfluidic platforms and analyze data to inform iterative process development.
Troubleshoot device and/or system issues and identify ways to optimize processes.
Analyze, interpret, document, and communicate results to cross-functional teams.
Collaborate with our internal R&D teams to translate project requirements into system specifications.
Maintain meticulous documentation of designs, cleanroom fabrication protocols, device master quality control (QC) characterizations, and experimental results to ensure traceability and facilitate knowledge transfer.
Support assay development workflows through reagent preparation, sample preparation, fluorescence-based readouts, and cell- or bead-based assay setup for antibody discovery applications.
Maintain an understanding of the latest research and advancements in the field, fostering innovation within our team.
Required Professional Experience & Qualifications
Bachelor or Master of Physics, Mechanical Engineering, Biomedical Engineering, or a related field.
Experience in 2D and 3D CAD design for custom device designs, e.g., AutoCAD, SolidWorks, and/or SolidEdge.
Demonstrable expertise in cleanroom-based microfabrication of microfluidics and/or MEMS devices, including mask alignment, UV photolithography, and PDMS soft lithography.
Experience with fabricating and quality checking PDMS devices, plus maintaining device and consumable inventories.
Experience with running and troubleshooting microfluidic experiments, particularly in droplet microfluidics.
Exposure to surface modification techniques to tailor microchannel properties for biological applications.
Proficiency in data processing and analysis to enable interpretation of results.
Excellent written and verbal communication skills to effectively present results and scientific data to team leaders, cross-functional teams, academic collaborators, or partners.
Preferred Professional Experience & Qualifications
Exposure to any combination of mask alignment, UV photolithography, imprint lithography, injection molding, metal deposition, wafer dicing, laser ablation, and/or thermal bonding in a cleanroom setting is advantageous.
Experience with supporting biological assay workflows, including reagent preparation, sample preparation, fluorescence-based readouts, cell-based screening workflows, or droplet-based antibody discovery assays, is advantageous.
Exposure to library screening or cell line development workflows, including vector cloning, transfection, selection, and expansion.
Ampersand Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Ampersand Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Ampersand and/or Flagship Pioneering or its employees is strictly prohibited unless contacted directly by Ampersand or Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Ampersand and FSP, and Ampersand/FSP will not owe any referral or other fees with respect thereto.
The salary range for this role is $65,000 - $107,300. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Ampersand currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Ampersand’s good faith estimate as of the date of publication and may be modified in the future.
Ampersand Biomedicines enables a new way of designing programmable medicines that work precisely where needed in the body and nowhere else. The company’s state-of-the-art computationally powered Address, Navigate, Design (AND)™ Platform continually learns the rules for identifying optimal localizer targets and refines its ability to design across the complex space of localizers and actuators. The result is increasingly sophisticated AND-Body™ therapeutics that are engineered across the physical constraints of molecules and the biological characteristics of the targets to effectively target the site of disease without affecting healthy tissue or cells. Ampersand Biomedicines was founded in 2020 at Flagship Labs, a unit of Flagship Pioneering.
How much do Science & Research jobs in Massachusetts pay?
Based on 4344 listings with disclosed salaries, most science & research jobs in Massachusetts pay between $90k–$240k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in Massachusetts right now?
There are currently 7,058 open science & research positions in Massachusetts listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Massachusetts?
Companies currently hiring include Mass General Brigham, Harvard Division of Medical Sciences, Takeda, Sanofi, Thermo Fisher Scientific, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Massachusetts?
Yes — 2160 of the 7058 open science & research positions offer remote or hybrid work (464 remote, 1696 hybrid).
How do I apply for Science & Research jobs in Massachusetts?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.