Cambridge, Massachusetts, United States · Hybrid
$212k–$333k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Process Engineering, Small Molecule Process Development, Scale-up, Commercialization, cGMP Operations
Cambridge, Massachusetts, United States · On-site
$149k–$215k/yr
Job Title: MSAT Analytical Specialist, DS and DP Synthetic Grade: L3-2 Hiring Manager: Olivier Schueller Location: Cambridge, MA About the Job The Analytical Technical Leader serves as SME supporting the MSAT Synthetics …
Skills: High-Performance Liquid Chromatography (HPLC), Dissolution Testing, Mass Spectrometry (MS), Method Development, Method Validation
Thousand Oaks, California, United States · On-site
$126k–$171k/yr
Career CategoryProcess DevelopmentJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with…
Skills: Solid Phase Peptide Synthesis, Peptide Purification, Peptide Characterization, cGMP Manufacturing, Technology Transfer
Cambridge, Massachusetts, United States · Remote OK
$252k–$308k/yr
Why Join Intellia? Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four cor…
Skills: Quality Management Systems, Digital Compliance, GxP Regulations, Risk Management, Regulatory Inspections
Cambridge, Massachusetts, United States · Remote OK
$319k–$390k/yr
Why Join Intellia? Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four cor…
Skills: Quality Management Systems, Digital Compliance, eQMS Implementation, Regulatory Compliance, Data Integrity
Thousand Oaks, California, United States · On-site
$126k–$171k/yr
Career CategoryProcess DevelopmentJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with…
Skills: Organic Chemistry, Synthetic Route Invention, Process Development, cGMP Manufacturing, Technology Transfer
Cambridge, Massachusetts, United States · On-site
$101k–$145k/yr
Job title: Senior Analytical Chemist - Solid State Characterization Location: Cambridge, MA About the job Sanofi is seeking a highly motivated individual to join our analytical group as a Senior Scientist for Solid State…
Skills: XRPD, DSC, TGA, Polymorphism Studies, Salt Selection
Cambridge, Massachusetts, United States · On-site
$149k–$215k/yr
Job Title: MSAT Industrialization Leader, Drug Product Synthetics Location: Cambridge, MA About the Job The DP Industrialization Lead ensures that drug product processes developed in late-stage R&D are robust, scalable, …
Skills: Process Manufacturing, Manufacturing Process Improvements, Integrated Planning, Pharmaceutical Development, Process Optimization
Cambridge, Massachusetts, United States · On-site
$137k–$215k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Material Qualification, Sustainability Strategy, Substances of Concern (SoC) Screening, Material Change Management, Quality Risk Management
Cambridge, Massachusetts, United States · On-site
Does it excite you to build something from the ground up, and do you have deep expertise in peptide process chemistry and leading high-performing teams? If this sounds like you, and you are ready to shape the future of p…
Skills: Peptide Process Chemistry, Team Leadership, Synthetic Route Scouting, Solid-Phase Peptide Synthesis, Liquid-Phase Peptide Synthesis
Cambridge, Massachusetts, United States · Hybrid
$154k–$243k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Drug Substance Leadership, Process Validation, Synthetic Small Molecule Development, Quality by Design, cGMP
Cambridge, Massachusetts, United States · On-site
Does it excite you to build something from the ground up, and do you have deep expertise in peptide process chemistry and leading high-performing teams? If this sounds like you, and you are ready to shape the future of p…
Skills: Peptide Process Chemistry, Team Leadership, Synthetic Route Scouting, Solid-Phase Peptide Synthesis, Liquid-Phase Peptide Synthesis
Cambridge, Massachusetts, United States · Hybrid
$146k–$234k/yr
The Role: Moderna is seeking an Operational Technology (OT) Response Engineer to strengthen our enterprise defense and incident response capabilities with a focus on protecting and responding to threats across OT environ…
Skills: Incident Response, OT Cybersecurity, Threat Detection, Threat Hunting, Splunk Enterprise Security
Cambridge, Massachusetts, United States · On-site
$100k–$275k/yr
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Program Management, Production Management, Earned Value Management (EVMS), Integrated Master Schedule (IMS), Risk Management
Cambridge, Massachusetts, United States · On-site
$82k–$220k/yr
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Cadence EDA, Siemens EDA, Gitlab, CI/CD, SOS
Dover, Delaware, United States · On-site
$65k–$87k/yr
Join us in becoming the premier die casting manufacturer and engineering solutions supplier worldwide. Quality Engineer – 1st Shift The Quality Engineer oversees all Quality Assurance functions at the plant level through…
Skills: Quality assurance, APQP, PPAP, PFMEA, Control plans
Dover, Delaware, United States · On-site
$83k–$100k/yr
Join us in becoming the premier die casting manufacturer and engineering solutions supplier worldwide. Assembly Supervisor About Us Orion Castings is North America’s leading full-service aluminum, zinc, and magnesium die…
Skills: Team leadership, Program management, Production coordination, Quality control, Process improvement
BiogenCambridge, Massachusetts, United States · Hybrid
$230k–$316k/yr
About This Role: As the Sr Director of Alliance Management, you will play a crucial role in establishing and nurturing relationships with Biogen’s partners. This position offers exposure to a diverse array of cross-funct…
Skills: Alliance Management, Contract Development, Stakeholder Management, Conflict Resolution, Negotiation
Dover, Delaware, United States · On-site
$17/hr–$25/hr
Join us in becoming the premier die casting manufacturer and engineering solutions supplier worldwide. Orion Castings Cambridge Division in North Billerica is looking to add energetic, detail-oriented, and motivated Asse…
Skills: Assembly, Die casting, Microscope operation, Hand tools, Power tools
Dover, Delaware, United States · On-site
$24/hr–$39/hr
Join us in becoming the premier die casting manufacturer and engineering solutions supplier worldwide. 2nd Shift CNC Setup Technician About Us Orion Castings is North America’s leading full-service aluminum, zinc, and ma…
Skills: CNC setup, CNC operation, Vertical mills, Horizontal mills, G-code
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
Lead the global Process Engineering team to develop robust and cost-effective manufacturing processes for synthetic molecule pharmaceuticals. Drive the global functional strategy, oversee technology transfer from pre-IND to commercial stages, and manage external collaboration networks.
Requires a degree in Chemical Engineering with 15 to 25+ years of industry experience depending on the degree level. Must have extensive expertise in small molecule scale-up, cGMP operations, and a proven track record of leading technical teams and regulatory submissions.
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.
OBJECTIVE:
Synthetic Molecule Process Development (SMPD) is responsible for developing robust, sustainable, and cost-effective processes for the manufacture of new synthetic molecule pharmaceuticals, ensuring high standards of quality, safety, and scalability.
The Sr. Director of Process Engineering will be responsible for organizational leadership for global Process Engineering team within SMPD and for driving global functional area strategy. Accountable for the performance and results of global Process Engineering group; strategic influence across Takeda Business Units and/or with external collaborators. Responsible for identification and application of relevant industry trends to inform operational strategy, with an emphasis on enterprise leadership, ensuring success for current and future programs within Process Engineering and SMPD broadly. Represents Takeda externally and drives external collaboration network strategy. Provide strategic and technical leadership for the global process engineering group, driving process design, optimization, and technology transfer for small molecule drug substance unit operations for the full development lifecycle from pre-IND to PPQ and Commercial tech transfer. The successful candidate will be accountable for establishing long-term technical vision, building organizational capability, and ensuring alignment with both pipeline needs and broader organizational objectives.
ACCOUNTABILITIES:
Defines the long-term vision and strategic roadmap for SMPD global process engineering capabilities, ensuring alignment across SMPD departments and Pharm Sci functions, as well as other business units (Quality, Regulatory, GSQ).
Accountable for the performance and results of global team, including performance management, talent development, succession planning, and building organizational capability across global regions.
Accountable for development and manufacturing of full synthetic molecule development in terms of leveraging process engineering expertise either directly or through leadership of team members
Establishes and manages operational processes across global Process Engineering within global SMPD.
Has full accountability for all engineering aspects for small molecule pipeline projects.
Directs team members in process development and optimization for key unit operations, including reaction engineering, crystallization, particle engineering, separations, and drying.
Oversees design, qualification, and operation of laboratory scale-down models to enable robust process scale-up.
Develops and oversees strategies for global Process Engineering infrastructure, resources, projects, etc. and implements relevant technologies and innovations.
Manages performance, personnel issues, and communication effectiveness within global Process Engineering
Accountable for the development of organizational culture and capabilities within global Process Engineering and global SMPD.
Defines and owns sourcing strategy for process engineering development and contributes materially and may own aspects of overall strategy for synthetic molecule development and manufacture.
Contributes to wider cross Business Unit strategy particularly with respect to Commercial (GSQ) development and manufacturing
Engages frequently with leadership of SMPD departments and Pharm sci functions, and other business units (Quality, Regulatory, and GSQ) to ensure investigational synthetic molecule engineering strategies are aligned at the operational workflow, Project, and Portfolio levels, where relevant.
Identifies and elevates awareness of topics for initiatives with impact across R&D/cross-divisional organization.
Leads complex, interdisciplinary initiatives and may sponsor a cross-departmental or cross-functional initiatives
Advises CMC teams on impact of team actions on other projects in their functional area and vice versa.
Utilizes technical expertise to contribute to R&D/cross-Business Unit strategy to solve complex issues.
Accountable for relevant technical content in regulatory filings (IND, NDA, MAA) and health authority queries.
Establishes and enforces best practices in process safety, quality by design (QbD), and risk management.
Builds and sustains strategic relationships with academic partners, consortia, and vendors to access cutting-edge science and capabilities.
Maintains external visibility and thought leadership through publications, invited talks, and representation in industry working groups.
EDUCATION, EXPERIENCE AND SKILLS:
Bachelor’s degree in Chemical Engineering and 25+ years relevant industry experience; Master’s degree in Chemical Engineering and 21+ years relevant industry experience; PhD in Chemical Engineering and 15+ years relevant industry experience.
Extensive experience in small molecule process development, scale-up, and commercialization.
Direct experience working in a manufacturing facility or pilot plant environment, with a strong understanding of cGMP operations, technology transfer, and scale-up.
Demonstrated leadership in facility design, start-up, or expansion projects, including defining user requirements, equipment selection, and commissioning.
Demonstrated success in leading teams and managing technical staff.
Strong track record of contributions to regulatory filings (IND/IMPD, NDA, MAA), including late-stage submissions.
Significant experience in working with external partners (CMOs/CDMOs) and managing complex technology transfers.
Expertise in process analytical technologies (FT-IR, NIR, FBRM, UV-vis, etc.), chemometrics, and modeling (statistical and first principles).
Experience with advanced process control strategies and continuous manufacturing.
Strong background in crystallization, particle engineering, and polymorph control.
Prior success in building new technical platforms and organizational capabilities.
Experience with process safety evaluation, risk assessments, and pilot plant operations.
Experience navigating changing external and internal environment and leading others through change by creating and inspiring and engaging workplace
Experience recommending, influencing and implementing organizational change and continuous innovation
Proven scientific track record through presentations at scientific conferences and publication of peer-reviewed manuscripts.
Knowledge and Skills:
Leadership: Proven ability to lead, mentor, and inspire high-performing technical teams.
Strategic Vision: Ability to define and implement long-term technical and organizational strategies.
Technical Depth: Recognized subject matter expertise in process engineering, with broad knowledge across reaction engineering, particle science, and scale-up.
Communication: Excellent written and verbal communication; able to influence across functions and present effectively to senior leadership and external stakeholders.
Collaboration: Strong cross-functional teamwork; ability to build relationships internally and externally.
Problem-Solving: Strong analytical, risk assessment, and decision-making skills.
External Engagement: Active involvement in professional networks, with a record of publications, presentations, or scientific leadership in the field.
TRAVEL REQUIREMENTS:
May require approximately 5-10% travel.
This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
U.S. Base Salary Range:
$212,000.00 - $333,190.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Better Health, Brighter Future
We strive to transform lives. While the science we advance is constantly evolving, our core purpose is enduring. For more than two centuries, our values have guided us to do what’s right for patients and for society. We know that changing lives requires us to do things differently. We start by listening to and addressing what really matters to patients, the people who love them, and those in the healthcare system who provide care. And that’s what inspires us all to be bold, push boundaries and set new standards that open up greater opportunities. Read our community guidelines: https://takeda.info/communityguidelines
Offices: Tokyo, JP · 1 Takeda Parkway, Deerfield, Illinois 60015, US · 40 Landsdowne St, Cambridge, Massachusetts 02139, US · Avenida das Nações Unidas, 14.401, Torre Jequitibá - 10°, 11° e 12° andares, São Paulo, 04794-000, BR · 43 Old Oak Rd, Bellville, Western Cape 7550, ZA
Based on 178 listings with disclosed salaries, most manufacturing jobs in Cambridge, MA pay between $74k–$225k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 215 open manufacturing positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Draper, Walden Robotics, Thermo Fisher Scientific, Lila Sciences, Amgen, among others. Browse the listings above to see every active employer.
Yes — 45 of the 215 open manufacturing positions offer remote or hybrid work (8 remote, 37 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
