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Provide strategic leadership and oversight for global Biostatistics teams across all therapeutic areas to drive excellence in study design and data analysis. Lead a global organization of 100-125 professionals while integrating AI, digital, and advanced statistical methodologies into late-stage development.
Requires a PhD or advanced degree in Statistics, Biostatistics, or Mathematics with over 15 years of senior-level pharmaceutical or biotech experience. Must possess deep knowledge of GCP, international regulations, and a proven track record of establishing successful internal and external partnerships.
As the Global Head of Biostatistics, you will provide strategic leadership and oversight across all Therapeutic Area (TA)-aligned Biostatistics teams, ensuring a cohesive and high-performing Biostatistics function that drives excellence in service of our strategy through study design, data analysis, and insights generation. You will report to the Global Head, PD Data Sciences & Analytics (PD-DSA), and you will be responsible for shaping the Biostatistics strategy across all therapeutic areas in alignment with broader PD-DSA and company objectives, as well as your organization’s overall performance. Your role will be instrumental in advancing innovative statistical methodologies, fostering collaboration across internal and external stakeholders, and ensuring the highest scientific rigor in all statistical activities.
You will lead a global, high-performing organization of approximately 100-125 Biostatistics professionals focused on late-stage development. Your direct reports will be a team of five therapeutic area-aligned Biostatistics Leaders. Sitting on the PD-DSA leadership team, you will collaborate with senior leaders in PD-DSA and beyond to influence and contribute to the overall strategy and success of late-stage development programs at Roche.
Develop and set a clear PD-DSA strategy and goals that align with Roche’s broader objectives, ensuring that you integrate Roche’s One Pharma strategy, PD goals, and R&D Excellence methods into the strategic direction
Embed and drive the adoption of PD-DSA’s strategic imperatives of Data, Digital/AI, and Design (the 3Ds) across your teams’ workflows, taking ownership of this mindset shift to ensure a seamless integration of these principles into daily operations
Act as a role model for your teams by delivering excellence in all aspects of your work (what you do, how you do it, and the impact you have), fostering a culture of learning, growth, and continuous improvement that empowers team members to reach their potential
Define and create clear accountability across each function in your organization and beyond, ensuring that you work in lock-step with your colleagues and partners to maintain alignment and drive cross-functional collaboration
Leadership and Strategy
Provide strategic leadership and oversight across all five Therapeutic Area-aligned Biostatistics leaders and their teams, ensuring a consistent and high-quality approach to Biostatistics across all therapeutic areas
Develop and implement a comprehensive Biostatistics strategy that aligns with Roche’s research and development objectives
Ensure that biostatistical considerations are integrated early in study designs and development programs, aligning with regulatory and scientific best practices
Partner closely with senior leadership across PD-DSA, clinical development, regulatory affairs, and data science teams to shape the future of statistical contributions within Roche
Represent Biostatistics as a strategic function, influencing high-level decision-making and driving cross-functional collaboration to optimize study designs and data strategies
Evaluate challenges as they arise and develop innovative solutions for teams to execute
Stakeholder Engagement and Partnerships
Act as the primary liaison between the Biostatistics function and key stakeholders across Clinical, Regulatory, and Data Science teams to drive alignment and shape outcomes for shared objectives; connect key stakeholders with therapeutic area Biostatistics Leaders as nuanced questions arise
Ensure seamless collaboration between Biostatistics and external partners, including regulatory agencies, academic institutions, and industry consortia
Represent Roche in industry forums, regulatory discussions, and cross-industry collaborations to influence and stay ahead of emerging biostatistics trends
Align closely with the PD-DSA-led Innovation Council and broader AI strategy to ensure Biostatistics contributes meaningfully to the company’s digital and AI transformation initiatives
Quality Oversight and Scientific Rigor
Ensure the highest scientific rigor and adherence to regulatory standards in all statistical methodologies and study designs across therapeutic areas.
Champion the adoption of AI, digital, and advanced statistical methodologies to enhance study designs and improve efficiency in data analyses.
Oversee the prioritization and implementation of modern digital and AI capabilities in study design and statistical approaches
Maintain and enforce compliance with industry regulations, GCP, and biostatistical best practices across all programs.
Team Development
Lead, inspire, and develop a high-performing global team of biostatistics leaders, ensuring their continued professional growth and ability to drive strategic impact
Establish a strong culture of accountability, innovation, and continuous learning within the Biostatistics function
Define clear performance metrics and success criteria for the Biostatistics function, ensuring alignment with organizational goals
Partner with P&C and leadership to attract, retain, and develop top biostatistical talent to support long-term organizational success
PhD, or other advanced degree in Statistics, Biostatistics, or Mathematics
More than 15 years experience (significant experience working at a senior level) in the pharmaceutical/biotech industry with an emphasis in molecule and molecule-enabling strategy; ability to consult and understand medical issues
In-depth knowledge of Good Clinical Practice (GCP), international and in-country regulations, guidelines and their application, and all other applicable compliance standards related to data and statistical sciences and industry conventions
Thorough understanding of the end-to-end drug development lifecycle, particularly on elements involving data and statistical sciences, advanced analytics methods and data visualization tools and techniques
Experience and understanding the new trends with all relevant data types (e.g., high-dimensional data) and analytics
Track record of establishing successful internal and external partnerships with relevant partner organizations and able to act as an ambassador for Roche
Willingness to adopt new technologies and methodologies, deep interest in AI and digital advancements
Influential and confident communicator
Strong English language skills
International travel as required - estimated at 20%
Relocation: Relocation assistance is being offered for this position
Locations: South San Francisco, Boston, Basel, Welwyn and Mississauga
The expected salary range for this position based on the primary location of South San Francisco, CA is $338,240 - $443,940. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
About Genentech We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours. If you’d like to join our team, view our openings at gene.com/careers. Our patient resource center is dedicated to getting patients and caregivers to the right resources. You can reach them at 1 (877) GENENTECH (436-3683) Monday-Friday, 6am-5pm PST or [email protected]. Community Guidelines: 1. We want to foster positive conversation around the issues we are passionate about. To that end, we remove profanity, content that contains threatening language, content that is aimed at private individuals, personal information, and repeated unwanted messages. 2. Don’t mention any medicines by name — ours or anyone else’s. Because of the fair balance rules governing our industry, we cannot post any comments that reference any pharmaceutical brand, product, or service. Please do not mention any specific medicines by name, or include any links to third party sites in your comments. 3. This isn’t the place to report or discuss side effects. This site is not intended as a forum for reporting side effects experienced while taking a Genentech product. Instead, you should report any side effects to Genentech Drug Safety at 1-888-835-2555. You can also report side effects of any prescription product directly to the FDA at 1-800-FDA-1088 or by visiting www.FDA.gov/medwatch. 4. Don’t pitch your product or service. Please don't use our page as a place to promote your product or pitch your services. Please also avoid posting links to external sites. We reserve the right to remove any posts that are deemed promotional.
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