Overview The Scientist IV Pharmacology Contractor will play a key scientific role in designing, executing, and interpreting preclinical pharmacology studies to support the discovery and development of novel anti-infectiv…
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$79/hr–$102/hr
Contract
bachelor degree, postgraduate degree
Posted 8d ago
Apply by Sep 4
~40 hrs/week
Responsibilities
The Scientist IV will design and execute preclinical pharmacology studies to support the development of novel anti-infective therapeutics. They will collaborate with cross-functional teams to analyze PK/PD data and ensure high-quality deliverables for project advancement.
Requirements
Candidates must hold a Ph.D. with 5+ years of industry experience, or an M.S. with 8+ years, or a B.S. with 10+ years. A strong background in preclinical pharmacology and experience with in vitro and in vivo models is required.
Full job description
Overview
The Scientist IV Pharmacology Contractor will play a key scientific role in designing, executing, and interpreting preclinical pharmacology studies to support the discovery and development of novel anti-infective therapeutics. This individual will contribute hands-on scientific expertise across in vitro and in vivo pharmacology, pharmacokinetics, toxicology, PK/PD, efficacy studies, and data interpretation to support compound advancement from early discovery through preclinical development.
The successful candidate will collaborate closely with cross-functional partners in microbiology, medicinal chemistry, and clinical development to generate high-quality pharmacology data that informs project strategy and decision-making.
Detailed Description
Essential Duties and Responsibilities
Design, develop, optimize, and execute in vitro, ex vivo, and in vivo pharmacology studies to evaluate pharmacokinetics, efficacy, safety, and pharmacodynamic response of anti-infective drug candidates.
Analyze and interpret pharmacology, pharmacokinetics, toxicology, efficacy, PK/PD, and biomarker data to guide compound selection, dose rationale, and project progression.
Contribute to study design for pharmacokinetic, toxicology, and efficacy models, including selection of appropriate models, endpoints, dosing regimens, controls, and statistical approaches.
Prepare study protocols, technical reports, data summaries, presentations, and regulatory-supporting documentation as needed.
Work closely with internal project teams and external CROs to coordinate study execution, monitor progress, troubleshoot issues, and ensure high-quality deliverables.
Collaborate with microbiology, medicinal chemistry, and clinical development teams to integrate findings/results into broader drug discovery and development strategies.
Maintain accurate, complete, and timely laboratory records and ensure work is conducted in accordance with applicable SOPs, safety requirements, and scientific best practices.
Review scientific literature and emerging technologies to identify opportunities to improve pharmacology study design, assay performance, and translational relevance.
Present scientific findings and recommendations to project teams, leadership, and external collaborators as appropriate.
May mentor junior scientists or research associates, providing technical guidance, scientific feedback, and support for professional development.
Qualifications
Ph.D. in microbiology, pharmacology, infectious disease biology, pharmaceutical sciences, biomedical sciences, or a related discipline with 5+ years of relevant industry experience; or M.S. with 8+ years of relevant industry experience; or B.S. with 10+ years of relevant industry experience.
Strong background in preclinical pharmacology, preferably within antibacterial, antifungal, or mycobacterial drug discovery and development.
Experience designing and interpreting in vitro and in vivo pharmacology studies, including pharmacokinetics, toxicology, efficacy models, PK/PD studies, dose-response assessments, and biomarker-supported analyses.
Working knowledge of drug discovery and preclinical development workflows, including candidate nomination, IND-enabling study support, and cross-functional project team interactions.
Experience coordinating studies with CROs or external collaborators is preferred.
Strong data analysis, scientific writing, presentation, and communication skills.
Demonstrated ability to work independently, manage multiple priorities, troubleshoot scientific challenges, and deliver high-quality results in a fast-paced environment.
Proficiency with commonly used data analysis and visualization tools; experience with pharmacokinetic and PK/PD modeling software is a plus.
On occasion, may be asked to work overnight shift or weekend.
Additional Information
The hourly rate for this position is $79 - $102. Individual pay is determined by several factors, which include but are not limited to: job-related skills, experience, and relevant education or training.
DISCLAIMER
The job description is not designed to cover or contain a comprehensive listing of requirements, duties or responsibilities that are required of the employee. Other requirements, duties and responsibilities may change or be assigned at any time with or without notice.
EEO
Shionogi Inc. is an equal opportunity employer supporting individuals with disabilities and veterans. All qualified applicants will receive equal consideration for employment opportunities based on valid job requirements without regard to race, color, religion, sex (including pregnancy), marital status, national origin, age, ancestry, citizenship, disability, genetic information, status as a disabled veteran, a recently separated veteran, Active Duty Wartime or Campaign Badge Veterans, and Armed Forces Service Medal Veterans, or any other characteristic protected by applicable law. It is the policy of Shionogi Inc. to undertake affirmative action for protected veterans and individuals with disabilities in compliance with all federal, state, and local requirements to recruit a diverse pool of protected veteran and individuals with disabilities applicants and to ensure that our employment practices are, in fact, non-discriminatory.
If you are qualified individual with a disability or a disabled veteran, you may request a reasonable accommodation if you are unable or limited in your ability to use or access this website to apply for a vacancy as a result of your disability. You can request accommodations by calling 973-307-3550 or by sending an email to [email protected].
Qpex Biopharma, Inc. a Shionogi Group Company, is a resistance-focused infectious disease company on a mission to make both a dramatic and sustainable improvement in patient care. Leveraging a multi-faceted approach and a deep understanding of drug resistance mechanisms, we are creating novel products and development. strategies that overcome multi-drug resistance. We are advancing a robust portfolio of treatments that will bring innovation to antibiotic development and deliver the right treatments to the right patients in the right settings. During the previous decade, our team brought 4 antibiotic products to regulatory approvals, with an extensive record of working with public- private partnerships, including partnerships with the Biomedical Advanced Research and Development Authority (BARDA) that led to the first approved antimicrobial drug product under that program in 2017. San Diego-based Qpex was launched in 2018 with investments from New Enterprise Associates, Adams Street Partners, LYZZ Capital, Hatteras Venture Partners and Stanford University Daper Fund. In July 2023, Qpex was acquired by Shionogi, Inc and is now a Shionogi Group Company.
Offices: 10075 Barnes Canyon Rd, San Diego, California 92121, US
Drug DiscoveryAnti-Infective TherapiesAntibioticsDrug DevelopmentDrug ResistanceMicrobiologyand Boron ChemistryBiotechnologyHealth Care
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