Engineering Jobs in Cambridge, MA (Now Hiring) — 786 open — Page 2
Relay Therapeutics
Senior Manager, Analytical Development & QC
Cambridge, Massachusetts, United States · On-site
$140k–$200k/yr
Senior+$1.7B raised
Your Role: You will lead and drive strategy for analytical method development and phase-appropriate method validation/transfer activities supporting full characterization of small molecule NCEs, from early development th…
Company Overview: Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with …
Skills: Flow cytometry, Cell sorting, Assay development, Data analysis, FlowJo
NORTH EAST REGION SITE SECURITY SPECIALIST The Site Security Specialist (Northeast) is a highly proactive, organized, and self-started security professional responsible for bringing corporate sites across Massachusetts (…
Cambridge, Massachusetts, United States · Remote OK
$120k–$215k/yr
Senior+$5.2B raised
Would you like to help define organizations secure the APIs, AI applications, and agentic systems that power modern business? Are you a product marketer who can go deep technically, turn complex security capabilities int…
Skills: API Security, AI Application Security, Technical Content Creation, Product Demonstrations, WAAP
About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead w…
About Kernal Biologics, Inc. Kernal Bio is a venture-backed therapeutics company engineering cells inside the body using AI-designed, selective mRNA and targeted LNP technology. By developing in vivo CAR-T therapies, Ker…
Cambridge, Massachusetts, United States · Remote Solely
Mid level
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Python, Test automation, Playwright, Selenium, Pytest
Consultant at Copenhagen Optimization (Cambridge, MA)
Cambridge, Massachusetts, United States · Hybrid
Mid level
Who are Copenhagen Optimization? At Copenhagen Optimization, we help some of the world’s busiest airports work smarter. Combining deep aviation expertise, data and our proprietary software platform, Better Airport®, we h…
Skills: Data analysis, Aviation industry knowledge, Consulting, Software implementation, Project management
Kensho is S&P Global’s hub for AI innovation and transformation. With expertise in machine learning, natural language processing, and data discovery, we develop and deploy novel solutions to innovate and drive progress a…
Skills: Python, Django, Typescript, Machine learning, Natural language processing
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Integrated circuit design, ASIC design, MATLAB, Simulink, System Verilog
Property Description Join the dynamic team at Hyatt Regency Boston Cambridge, located in the vibrant and innovative city of Cambridge, Massachusetts! As a prestigious hotel in the heart of Kendall Square, we are seeking …
Skills: Refrigeration, Mechanical systems maintenance, Electrical systems maintenance, Preventive maintenance, HVAC
Kensho is S&P Global’s hub for AI innovation and transformation. With expertise in machine learning, natural language processing, and data discovery, we develop and deploy novel solutions to innovate and drive progress a…
Skills: Machine learning, Python, PyTorch, Natural language processing, Generative AI
Here at Humanoid, we believe in a future where robots amplify human potential. That’s why we’ve set out on a mission to build the world’s most capable, commercially-scalable, and safe humanoid robots. We’re bringing that…
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Are you ready to dive into the world of transformative therapies and make a significant impact? At EsoBiotec, now part of AstraZeneca, we are setting new benchmarks for biotechnological research. Our collaboration combin…
Skills: In vivo pharmacology, Oncology models, Flow cytometry, Viral vectors, Molecular analysis
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Solid-state physics, MEMS, Control systems, Inertial instruments, Sensor design
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: Program management, Earned Value Management, Integrated Master Plan, Integrated Master Schedule, Risk management
At Audible, we believe stories have the power to transform lives. It’s why we work with some of the world’s leading creators to produce and share audio storytelling with our millions of global listeners. We are dreamers …
Thousand Oaks, California, United States · On-site
$115k–$156k/yr
Senior$29B raised
Career CategoryEngineeringJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious…
Skills: Process development, Technology transfer, Scale-up, Risk assessment, Process modeling
Machine Learning Engineer (Robotics and AI Institute LLC):
Cambridge, Massachusetts, United States · On-site
$186k–$238k/yr
Mid level
Design, develop, and improve software technology used in robotic applications. Reimagine robot prototypes to solve the most important and fundamental challenges in AI and robotics. Architect scalable infrastructure for m…
Skills: C++, Python, Machine Learning, Deep Learning, Robotics
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$140k–$200k/yr
Full-time
bachelor degree, postgraduate degree
Posted 1d ago
~40 hrs/week
Responsibilities
Lead the analytical strategy for small molecule drug substance programs, overseeing method development, validation, and QC testing at CDMOs. Partner with CMC, Quality Assurance, and Regulatory Affairs to ensure regulatory readiness and scientific rigor for clinical candidates.
Requirements
Requires a Ph.D. in Analytical Chemistry or related field with 8+ years of industry experience, or equivalent experience with a Master's or Bachelor's degree. Must possess deep technical expertise in small molecule analytical instrumentation and a strong command of global regulatory guidelines.
Full job description
Your Role:
You will lead and drive strategy for analytical method development and phase-appropriate method validation/transfer activities supporting full characterization of small molecule NCEs, from early development through late-stage/commercial readiness.
Own the analytical strategy for drug substance programs at CDMOs, directing method development, validation, and troubleshooting to enable characterization, release, and stability testing of Relay clinical candidates.
Provide senior-level review and approval of method transfer/validation protocols, data sets, and reports, ensuring scientific rigor and regulatory readiness.
Hold accountability for QC testing oversight across analytical testing labs and DS manufacturing sites, including vendor performance and quality of deliverables.
Review and approve method qualification protocols and reports at external laboratories, serving as the final scientific authority on method suitability.
Direct the review and QC of raw data from third parties supporting batch release and stability; lead data trending efforts, proactively flag risks to the team, and drive resolution of issues.
Manage a portfolio of concurrent projects, prioritizing resources and timelines across programs in a fast-paced, evolving environment.
Serve as a cross-functional leader, partnering with CMC, Quality Assurance, and Regulatory Affairs to shape regulatory and development strategy, and representing Analytical Development in cross-functional and external-facing forums.
Your Background:
Ph.D. in Analytical Chemistry, Biotechnology, or a related discipline with a minimum of 4+ years of relevant industry experience (or MS with 6+ years, or BS with 8+ years) in small molecule pharmaceutical analytical development.
Demonstrated expertise leading analytical method development, validation, troubleshooting, and quality control programs, including experience directing work performed at external CMOs/CROs.
Deep, hands-on analytical knowledge and technical authority in small molecule analytical methods for drug substance and solid-state characterization.
Strong working expertise across analytical instrumentation including HPLC, GC, KF titration, XRPD, ICP-MS, UV, and solid-state characterization techniques, with the judgment to guide method selection and troubleshooting strategy.
A confident, articulate communicator and cross-functional influencer, capable of representing Analytical Development with contract laboratories, manufacturing partners, and internal leadership.
Proven ability to lead through ambiguity and shifting priorities in a fast-paced environment, balancing multiple high-visibility programs against firm timelines.
Previous experience filing or working on IND and/or CTA filings is a plus.
Strong command of regulatory and analytical guidelines, including cGMPs, ICH, FDA, USP, and other global regulatory requirements, with experience applying this knowledge to shape submission strategy.
Estimated Salary Range: [$121,000 - $172,000].
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#BP1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
Integrating leading-edge computational and experimental science to transform human health.
Industry
Biotechnology Research
Company size
51-200 employees
Founded
2016
Headquarters
Cambridge, Massachusetts
LinkedIn followers
33,849
Total funding
$1.7B
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, our approach combines unprecedented computational power with leading-edge experimental approaches across the fields of structural biology, biophysics, chemistry and biology. By applying these insights, we believe we have a differentiated approach to drug protein targets based on their motion, enabling us to select and advance unique product candidates that can be developed into novel therapies for patients.
Located in Cambridge, Massachusetts, our world-class team is equal parts bright and bold, with a shared passion for working in intellectually stimulating environments. If you're creative, collaborative and passionate about making a difference in the lives of patients, join us!
Offices: 60 Hampshire St, Cambridge, Massachusetts 02139, US
Protein MotionAllosteric Drug DiscoveryStructural BiologyBiophysicsComputationChemistryCancer BiologyClinical DevelopmentPrecision OncologyBreast Cancer
Frequently asked questions
How much do Engineering jobs in Cambridge, MA pay?
Based on 627 listings with disclosed salaries, most engineering jobs in Cambridge, MA pay between $82k–$240k per year. Individual offers vary with seniority, company size, and specialization.
How many Engineering jobs are open in Cambridge, MA right now?
There are currently 786 open engineering positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Engineering roles in Cambridge, MA?
Companies currently hiring include Draper, Lila Sciences, Akamai Technologies, Flagship Pioneering, Harvard Division of Medical Sciences, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Engineering jobs in Cambridge, MA?
Yes — 236 of the 786 open engineering positions offer remote or hybrid work (58 remote, 178 hybrid).
How do I apply for Engineering jobs in Cambridge, MA?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.