San Francisco, California, United States · Hybrid
$266k–$468k/yr
About the Team OpenAI develops models that can reason through complex problems and hardware designed for the demands of advanced AI. AI for Chips connects these efforts: applying increasingly capable AI systems to the wo…
Skills: Software engineering, Reinforcement learning, Chip design, RTL generation, Verification
San Francisco, California, United States · Hybrid
$40/hr–$64/hr
Job Summary: The Helen Diller Family Comprehensive Cancer Center (HDFCCC) is seeking a Clinical Research Coordinator (CRC) to join the Cancer Immunotherapy Research & Clinical Translation (CIRCT) Program within the Divis…
Skills: Clinical research, Oncology, Data management, Regulatory compliance, Patient recruitment
SolveaSan Francisco, California, United States · On-site
$150k–$300k/yr
About Solvea Solvea is building simulations for high-stakes decisions. In our rapidly changing world, leaders are forced to act with imperfect information. Solvea helps them move with conviction by simulating these high-…
Skills: Data platform, AI product development, Simulation, Data gathering, Voice agents
SolveaSan Francisco, California, United States · On-site
$150k–$300k/yr
About Solvea Solvea is building simulations for high-stakes decisions. In our rapidly changing world, leaders are forced to act with imperfect information. Solvea helps them move with conviction by simulating these high-…
Skills: Artificial intelligence, Product design, Software development, Research, Simulation modeling
San Francisco, California, United States · Hybrid
$150k–$190k/yr
Job Title: Manager/Senior Manager Accounting Location: San Francisco, CA (hybrid) Position Type: Full Time Reports to: VP, Corporate Controller Position Summary Latigo Biotherapeutics is seeking a hands-on Accounting Man…
Skills: Accounting, Financial Reporting, GAAP, Month-end Close, Reconciliations
San Francisco, California, United States · On-site
$143k–$271k/yr
The Opportunity The Speech AI Lab at Adobe Research is seeking a Senior Audio Research Scientist to join our speech generative AI and multimodal research efforts, based in San Francisco. This role is ideal for researcher…
Skills: Speech AI, Generative AI, Audio modeling, Multimodal learning, Machine learning
San Francisco, California, United States · Hybrid
$40/hr–$64/hr
Job Summary: The Clinical Research Coordinator will perform independently or with general direction at the fully operational journey level of the series to execute, manage, and coordinate research protocols, as directed …
Skills: Clinical research coordination, Data collection, Participant recruitment, Informed consent, Regulatory compliance
San Francisco, California, United States · On-site
Research Engineer At XDOF, we’re at an inflection point. Frontier labs are racing to build general-purpose robots, and high-quality training data is the bottleneck. We’re building the foundation behind the foundation mod…
Skills: C++, CUDA, Python, Machine Learning, Performance Optimization
Domera LabsSan Francisco, California, United States · On-site
$110k–$200k/yr
Technology that speaks your language Domera Labs builds Ami, the first AI companion for seniors. Ami brings the power of a smartphone into a more human form: voice-first and deeply personalized We at Domera Labs are reth…
Skills: Python, Deep learning, LLMs, Speech models, ASR
San Francisco, California, United States · On-site
$40/hr–$64/hr
This 50% position (20 hours per week) will involve conducting on-site study visits at UCSF Benioff Children’s Hospitals in San Francisco (Mission Bay) and Oakland. Flexibility is required, since the needs of the study wi…
Skills: Clinical research coordination, Participant recruitment, Data entry, Regulatory maintenance, IRB submissions
San Francisco, California, United States · On-site
$380k–$460k/yr
About the Team Our Robotics team is focused on unlocking general-purpose robotics and pushing towards AGI-level intelligence in dynamic, real-world settings. Working across the entire model stack, we integrate cutting-ed…
Skills: Robotics, Control systems, C++, Rust, Motion control
San Francisco, California, United States · Hybrid
$300k–$330k/yr
Medical Director, Early Phase Clinical Development Location: Thousand Oaks, CA or San Francisco, CA Reports To: Executive Director, Clinical Development The Medical Director will support the planning, execution, oversigh…
Skills: Clinical Development, Medical Monitoring, Clinical Pharmacology, Pharmacovigilance, Protocol Development
San Francisco, California, United States · On-site
$140k–$210k/yr
Wanna join the adventure? Loft Orbital flies other people's payloads and software on standardized satellites, and we are building the first marketplace for space-based AI applications: the store where partners publish, d…
Skills: Full stack development, TypeScript, React, Python, Go
San Francisco, California, United States · Hybrid
Midjourney is seeking physicists to develop revolutionary quantum hardware technologies. Minimum qualifications: Multiple years of experience working in experimental quantum physics (Ph.D.-level or similar) Proficiency i…
Skills: Experimental quantum physics, Laser-based optical measurements, Optics, Optoelectronics, Photodetectors
San Francisco, California, United States · On-site
About Us At moss.ag, we build robots to go where humans won't, digitizing the physical outdoor world to make it machine-readable. Starting with tree farms — where a single field holds millions of plants no human has ever…
Skills: Machine Learning, Computer Vision, Robotics, Python, C++
San Francisco, California, United States · On-site
$150k–$250k/yr
The Mission GRAM is a self replication company creating populations of insectoids for the physical economy. Our first research frontier is self-preservation: the base case of physical self-replication. Our machines will …
Skills: C++, Python, ROS 2, Robotics, Control systems
San Francisco, California, United States · On-site
$160k–$200k/yr
The Mission GRAM is a self replication company creating populations of insectoids for the physical economy. Our first research frontier is self-preservation: the base case of physical self-replication. Our machines will …
Skills: Magnetic circuit design, Finite-element analysis, Ansys Maxwell, COMSOL, JMAG
San Francisco, California, United States · On-site
$130k–$170k/yr
Thornton Tomasetti applies engineering and scientific principles to solve the world’s challenges. An independent organization of creative thinkers and innovative doers collaborating from offices worldwide, our mission is…
Skills: Geotechnical Engineering, Forensic Investigation, Litigation Support, Risk Loss Consulting, Repair Design
San Francisco, California, United States · On-site
Founding AI Research Lead - Agentic AI Lab San Francisco Bay Area | Full time Backed by 8VC, we are building a world-class team to tackle one of industry's most critical problems: trusted AI for enterprise operations. Ab…
Skills: Machine Learning, PyTorch, Reinforcement Learning, Sequence Modeling, Data Engineering
San Francisco, California, United States · On-site
We’re building the scientific intelligence platform for the physical world, to accelerate breakthroughs in semiconductors, batteries, advanced materials, aerospace, and beyond. These industries represent trillions in spe…
Skills: Technical troubleshooting, Data analysis, Product configuration, Prototyping, Scientific fluency
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You will build and maintain research infrastructure for reinforcement learning environments and integrate EDA tools into chip-design workflows. Additionally, you will collaborate with researchers to develop model harnesses and improve the reliability and performance of experiment systems.
The role requires strong software engineering fundamentals with experience in designing and debugging reliable systems. Candidates should be comfortable working with researchers on evolving requirements and possess experience or interest in chip-design tools and reinforcement learning.
OpenAI develops models that can reason through complex problems and hardware designed for the demands of advanced AI. AI for Chips connects these efforts: applying increasingly capable AI systems to the work of semiconductor engineering.
Our goal is to help engineers develop better chips and shorten design cycles. This work brings research, model training, and hardware expertise together to build tools that engineers can use on real designs, with correctness and measurable performance at the center.
We’re hiring a Software Engineer to build the research infrastructure and tooling that help OpenAI models design silicon. You’ll turn chip-design workflows into reliable environments for reinforcement learning and evaluation, and make it easier for researchers to run experiments and iterate on new ideas.
You’ll move between software engineering, tool integration, and open research problems. We value strong coding fundamentals, clear technical judgment, and independent execution. Prior chip-design experience is helpful, but you can learn the domain alongside the team’s hardware specialists.
Build and maintain infrastructure for reinforcement learning environments, evaluations, and long-running experiments.
Integrate electronic design automation (EDA) tools into workflows for RTL generation, verification, and physical design optimization.
Improve experiment reliability, reproducibility, observability, and performance; debug failures across tools, services, and infrastructure.
Develop tooling and model harnesses that let researchers test ideas quickly and measure correctness and power, performance, and area (PPA).
Collaborate with researchers and engineers to turn successful experiments into reusable systems and training workflows.
Own ambiguous projects end to end, communicate progress, and use results to guide the next iteration.
Have strong software engineering fundamentals, with experience designing, implementing, and debugging reliable systems.
Can work across a stack, investigate unfamiliar failures, and make practical tradeoffs between speed, correctness, and maintainability.
Have independently delivered substantial software projects and can explain your technical decisions and their impact.
Are comfortable working with researchers on evolving requirements and turning open-ended problems into working software.
Are interested in learning how reinforcement learning and chip-design tools fit together.
Care about developing safe, beneficial AI.
Experience with research infrastructure, distributed systems, experiment orchestration, or ML tooling.
Familiarity with reinforcement learning, model evaluations, or training workflows.
Experience with Python, containerized tools, and reproducible development environments.
Experience with RTL, Verilog/SystemVerilog, EDA tools, formal verification, or chip-design automation.
To comply with U.S. export control laws and regulations, candidates for this role may need to meet certain legal status requirements as provided in those laws and regulations.
OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity.
We are an equal opportunity employer, and we do not discriminate on the basis of race, religion, color, national origin, sex, sexual orientation, age, veteran status, disability, genetic information, or other applicable legally protected characteristic.
For additional information, please see OpenAI’s Affirmative Action and Equal Employment Opportunity Policy Statement.
Background checks for applicants will be administered in accordance with applicable law, and qualified applicants with arrest or conviction records will be considered for employment consistent with those laws, including the San Francisco Fair Chance Ordinance, the Los Angeles County Fair Chance Ordinance for Employers, and the California Fair Chance Act, for US-based candidates. For unincorporated Los Angeles County workers: we reasonably believe that criminal history may have a direct, adverse and negative relationship with the following job duties, potentially resulting in the withdrawal of a conditional offer of employment: protect computer hardware entrusted to you from theft, loss or damage; return all computer hardware in your possession (including the data contained therein) upon termination of employment or end of assignment; and maintain the confidentiality of proprietary, confidential, and non-public information. In addition, job duties require access to secure and protected information technology systems and related data security obligations.
To notify OpenAI that you believe this job posting is non-compliant, please submit a report through this form. No response will be provided to inquiries unrelated to job posting compliance.
We are committed to providing reasonable accommodations to applicants with disabilities, and requests can be made via this link.
OpenAI Global Applicant Privacy Policy
At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.
OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. AI is an extremely powerful tool that must be created with safety and human needs at its core. OpenAI is dedicated to putting that alignment of interests first — ahead of profit. To achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity. Our investment in diversity, equity, and inclusion is ongoing, executed through a wide range of initiatives, and championed and supported by leadership. At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.
Offices: San Francisco, CA 94110, US
Based on 1377 listings with disclosed salaries, most science & research jobs in San Francisco, CA pay between $101k–$305k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 1,946 open science & research positions in San Francisco, CA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include UCSF Department of Anesthesia and Perioperative Care, OpenAI, Anthropic, Sutter Health, Astranis Space Technologies, among others. Browse the listings above to see every active employer.
Yes — 765 of the 1946 open science & research positions offer remote or hybrid work (128 remote, 637 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
