San Francisco, California, United States · On-site
$175k–$240k/yr
Mid level$66M raised
About us Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biol…
San Francisco, California, United States · On-site
$200k–$400k/yr
Mid level$481M raised
About Decagon Decagon is the leading conversational AI platform empowering every brand to deliver concierge customer experiences. Our technology enables industry-defining enterprises like Avis Budget Group, Block’s Cash …
Skills: AI/ML engineering, AI safety, Language models, Agentic systems, Reinforcement learning
San Francisco, California, United States · On-site
$194k–$265k/yr
Senior+$412M raised
We are rebuilding biotech for the AI era. When a breakthrough is delayed, the world waits. Getting a molecule from discovery to patients, or a crop from lab to field, involves thousands of slow, manual, disconnected step…
Skills: Software Engineering, Python, React, LLM, AI Agents
Biogen
Director, Biotherapeutics Discovery
San Francisco, California, United States · On-site
$204k–$281k/yr
Senior+
On Site - South San Francisco. About This Role At Biogen, we are committed to discovering, developing, and delivering innovative therapies for people living with serious neurological and immunological diseases. In this r…
San Francisco, California, United States · On-site
Entry level$302M raised
Join the Sleep Fitness Movement At Eight Sleep, we’re on a mission to fuel human potential through optimal sleep. As the world’s first sleep fitness company, we’re redefining what it means to be well-rested and building …
Skills: Human factors research, User testing, Data collection, IRB submissions, HIPAA compliance
San Francisco, California, United States · On-site
$120k–$180k/yr
Entry level$9M raised
About Blumen Blumen is building the regulatory intelligence layer for American infrastructure. Our platform combines regulatory information with more than 2,500 geospatial datasets to help energy companies and environmen…
Skills: Regulatory Research, Data Entry, Quality Control, Attention To Detail, Data Structuring
Nunchux AI
Product Engineer
San Francisco, California, United States · Hybrid
$170k–$240k/yr
Mid levelVisa sponsorship
About Nunchux AI Nunchux AI builds infrastructure that makes multimodal generative AI faster and cheaper to serve, and easier to build on. Founded by MIT PhDs Muyang Li, Yujun Lin, and Zhekai Zhang with CMU Professor Jun…
Outset invented a better way to do research: AI-powered user interviews. Global brands like Hubspot, Microsoft, Uber and Nestle use Outset to achieve deeper, qualitative insights about their users at unprecedented speed …
San Francisco, California, United States · Remote OK
$195k–$288k/yr
Senior$4.5B raised
About the RoleDevelop software programs, algorithms, and automated processes that cleanse, integrate, and evaluate large, complex datasets from multiple disparate sources. Manipulate and engineer data across diverse doma…
San Francisco, California, United States · On-site
$216k–$281k/yr
Senior$3M raised
Meet the Team At Foundation AI, we are leading frontier AI research across Cisco. Our mission is to advance the state of artificial intelligence through fundamental research and translate scientific breakthroughs into di…
Skills: Artificial intelligence, Machine learning, Foundation models, Python, PyTorch
San Francisco, California, United States · On-site
$100k–$140k/yr
Senior$395M raised
About Mariana Minerals Mariana Minerals is a software-first, vertically integrated minerals company on a mission to supply the critical minerals powering modern energy, AI, and defense technologies. We’re reimagining the…
Skills: Team Leadership, Pilot Plant Operations, Chemical Process Monitoring, EHS Compliance, Hazard Assessment
Registered Nurse - Adult Internal Medicine (FT, Day)
San Francisco, California, United States · On-site
$93/hr–$121/hr
Mid level
Utilizes the nursing process for assessment, planning, implementation, and evaluation to provide safe, therapeutic care. Functions as a member of the interdisciplinary and nursing teams; carries out established nursing p…
San Francisco, California, United States · On-site
$200k–$400k/yr
Mid level$481M raised
About Decagon Decagon is the leading conversational AI platform empowering every brand to deliver concierge customer experiences. Our technology enables industry-defining enterprises like Avis Budget Group, Block’s Cash …
Skills: AI/ML engineering, AI safety, Language models, Agentic systems, Reinforcement learning
The Division of Gastroenterology at UCSF Health consists of 150 faculty, fellows, and staff whose work is grounded in a deep commitment to the highest standards of clinical care and teaching, as well as research leading …
Skills: Research Administration, Financial Analysis, Budget Management, Grant Management, Contract Administration
About Plasmidsaurus Plasmidsaurus is on a mission to accelerate new cures and promote a healthier planet by unlocking a new level of productivity for scientists. Our sequencing services are used daily by thousands of inn…
Skills: Accounting, Accounts Payable, Inventory Accounting, Month-end Close, US GAAP
To get the best candidate experience, please consider applying for a maximum of 3 roles within 12 months to ensure you are not duplicating efforts. Job Category Software Engineering Job Details About Salesforce Salesforc…
About Gridware Gridware is a San Francisco-based technology company dedicated to protecting and enhancing the electrical grid. We pioneered a groundbreaking new class of grid management called active grid response (AGR),…
San Francisco, California, United States · On-site
$175k–$240k/yr
Mid level$66M raised
About us Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biol…
Business Development Associate / Manager - Medical Communications & Life Sciences
San Francisco, California, United States · Remote OK
$120k–$160k/yr
Senior
About the Opportunity We are looking for an experienced Business Development Associate / Manager to help expand a growing global medical and scientific communications organization in the United States. The organization w…
Skills: Business Development, Medical Communications, Life Sciences, Consultative Selling, Account Management
Description POSITION: Full Time LOCATION: Hybrid (Greater Farallones National Marine Sanctuary/Cordell Bank National Marine Sanctuary, San Francisco, CA) Relocation No relocation offered for this position Pay $30 - $38 p…
Skills: Marine ecological field sampling, Data management, Data analysis, ArcGIS, Science communication
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
$175k–$240k/yr
Full-time
bachelor degree
Competitive salary, Equity, Full healthcare coverage, New parent stipend, Fertility coverage, Mental health support
Posted 7d ago
~40 hrs/week
Responsibilities
You will architect, implement, and maintain AI scientist agents from prototype through production while collaborating with internal science and engineering teams. Additionally, you will spend time with R&D partners to understand workflows and translate those insights into product direction.
Requirements
Candidates should have 4+ years of professional software engineering experience with a strong foundation in computer science or related technical fields. Proficiency in Python or TypeScript and experience building LLM-powered tools or agent architectures are required.
Full job description
About us
Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biology, physics, chemistry, and AI.
The Role
We're looking for an Agent Engineer to join the team responsible for building Edison's AI agents. This team owns the development and design of our AI scientist agent, Kosmos.
You'll own the development and maintenance of production agents, prototype new capabilities with our internal science and engineering teams, and shape how our platform evolves. You'll spend some time with customers to understand real workflows and validate what you're building, but your primary focus is on the agents themselves – making them more capable, more reliable, and more useful across the life sciences.
Responsibilities
Architect, implement, and maintain the AI agents that power Edison's platform, from prototype through production.
Work with our internal science and engineering teams to explore new agent architectures, prompting strategies, tool integrations, and evaluation frameworks.
Develop reusable infrastructure – agent skills, tool-use pipelines, benchmarks – that improves every agent on the platform.
Spend time with R&D partners (~30%) to understand their workflows, test what you've built in real environments, and bring insights back to the team.
Translate field insights and internal research into product direction – help the team prioritize what to build next.
Qualifications
Typically, 4+ years of professional software engineering experience, with production experience shipping systems that real users depend on.
Experience building LLM-powered tools or applications: prompting, context engineering, agent architectures, evaluation frameworks.
Strong engineering foundation in Computer Science, Software Engineering, Mathematics, Physics, Data Science, or a related technical field.
Proficiency in Python and/or TypeScript, with comfort picking up new tools and frameworks quickly.
Able to work across engineering, science, and product teams.
Comfortable building from scratch, driving clarity in ambiguous situations, and wearing multiple hats.
Bonus points for
Experience in life sciences, biomedical research, scientific computing, or technical R&D workflows.
Experience building agent systems, tool-use pipelines, or evaluation/benchmarking frameworks for AI applications.
Contributions to open-source scientific or AI tooling.
Why join us?
We're a fast-moving, mission-driven culture where smart people do their best work and actually enjoy doing it. We also offer full-time employees the following:
Competitive salary and equity
Full healthcare coverage; we pay 100% of premiums for you and your dependents
Support for growing families, including a yearly new parent stipend and fertility coverage through Carrot
Mental health support through Rula, our in-network therapist and psychiatrist network with fast availability
12 weeks of paid parental leave for maternity, paternity, and adoption
Pet care support with a yearly employer-funded stipend for your animal companions
Commuter benefits so you can pay for transit and parking with pre-tax dollars
401(k) company matching
$300 health and wellness benefit quarterly
Lunch is on us every day you're in the office, and dinner is on us when you're working late
Regular team off-sites and company events
Edison Scientific is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected characteristic under applicable law.
Edison Scientific is building the AI platform for scientific research and development. Kosmos, our AI scientist, collaborates with teams across the full R&D lifecycle, leveraging proprietary data and organizational context to help navigate complex scientific decisions and accelerate timelines from discovery to FDA approval.
We believe the full gains from AI in science will only be realized when AI systems are integrated across the entire research and development stack, continuously learning from the evolving scientific context inside an organization. With Edison Scientific, scientists and researchers remain at the center of scientific progress, using AI to amplify their expertise and accelerate discovery at unprecedented speed.
Edison is a scientist-led company that was spun out of the nonprofit research lab FutureHouse in 2025, backed by $70M from Spark Capital, Triatomic Capital, Susa Ventures, Pillar Ventures, among other investors.
How much do Science & Research jobs in San Francisco, CA pay?
Based on 1377 listings with disclosed salaries, most science & research jobs in San Francisco, CA pay between $101k–$305k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in San Francisco, CA right now?
There are currently 1,946 open science & research positions in San Francisco, CA listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in San Francisco, CA?
Companies currently hiring include UCSF Department of Anesthesia and Perioperative Care, OpenAI, Anthropic, Sutter Health, Astranis Space Technologies, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in San Francisco, CA?
Yes — 764 of the 1946 open science & research positions offer remote or hybrid work (128 remote, 636 hybrid).
How do I apply for Science & Research jobs in San Francisco, CA?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.