Science & Research Jobs in Massachusetts (Now Hiring) — 6,981 open — Page 206
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company
Associate Director, Analytical Development – Small Molecule
Boston, Massachusetts, United States · On-site
$180k–$195k/yr
Senior+
Description of Role Centessa continues to expand its CMC group and currently seeks an Associate Director of Analytical R&D within the CMC group. The successful candidate will have hands-on experience leading the executio…
Skills: Analytical Development, Small Molecule, cGMP, Method Validation, CDMO Management
Statistical Programming Lead, Clinical Development Data Services, R&D, Orion Corporation
Boston, Massachusetts, United States · Hybrid
$130k–$230k/yr
Senior+
Statistical Programming Lead will join a growing oncology-focused Data Sciences function and provide strategic and operational leadership for statistical programming activities supporting oncology drug development progra…
Skills: SAS Programming, CDISC Standards, SDTM, ADaM, R
Senior / Principal Statistical Programmer, Clinical Development Data Services, R&D, Orion Corporation
Boston, Massachusetts, United States · Hybrid
$100k–$180k/yr
Senior
As a Senior Statistical Programmer in a growing Data Sciences function, you are responsible for developing, validating, and delivering clinical trial datasets, statistical outputs, and regulatory submission deliverables …
Overview POSITION SUMMARY: Under the direction of the Principal Investigator (PI) or designee, the Clinical Research Coordinator is responsible for independently performing delegated tasks and procedures involving human …
Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble…
Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes. We built a leading performance-driven network of 100+ sites across the US, Eu…
Skills: EHR Review, Patient Recruitment, Clinical Trial Operations, Data Management, Protocol Interpretation
Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes. We built a leading performance-driven network of 100+ sites across the US, Eu…
Skills: EHR Review, Patient Recruitment, Clinical Trial Operations, Data Management, Protocol Interpretation
Minimum qualifications: Bachelor's degree in Mechanical Engineering, Product Design, Electrical Engineering, a related field, or equivalent practical experience. 2 years of experience working in a robotics technical envi…
Principal Scientist / Associate Director, Agentic AI Research for Materials Science
San Francisco, California, United States · On-site
$288k–$420k/yr
Senior$551M raised
Your Impact at LILA Own the technical direction for agentic AI systems applied to materials science at Lila. You will set and execute the roadmap for autonomous agents that plan, run, and interpret materials experiments,…
You will join a growing oncology-focused Data Sciences function and provide statistical support across Phase I–III oncology studies within our expanding portfolio. The Senior Biostatistician contributes to the design, an…
You will join a growing oncology-focused Data Sciences function and serve as the lead statistician for one or more oncology development programs, providing statistical leadership across Phase I–III clinical trials. This …
Skills: Biostatistics, Oncology Drug Development, Clinical Study Design, Regulatory Submissions, Bayesian Methods
Overview Under the direction of the Principal Investigator (PI) or designee, the Clinical Research Coordinator I is responsible for independently performing delegated tasks and procedures involving human subject research…
Skills: Clinical Research Coordination, Regulatory Compliance, Participant Recruitment, Informed Consent, Data Management
Clinical Study Delivery Lead, Global Clinical Operations, Oncology Therapy Area, R&D, Orion Corporation
Boston, Massachusetts, United States · Hybrid
$140k–$230k/yr
Senior+
The Clinical Study Delivery Lead provides global leadership for the planning, set up, execution, oversight, and delivery of complex oncology clinical trials from First in Human (FIH) through late phase Ph2/3 registration…
Are you a visionary scientist with a passion for oncology and translational research? Do you thrive at the intersection of discovery and clinical development? We are seeking a scientifically and technically rigorous Tran…
Gloucester, Massachusetts, United States · On-site
Mid level
Dermatologist – Gloucester, MA (Opening 2027) Optima Dermatology is seeking a Board Certified / Board Eligible General Dermatologist to join our new practice in Gloucester, MA. This is an exceptional opportunity to pract…
Skills: General Dermatology, Patient Care, Clinical Excellence, EMR Proficiency, Biologics Coordination
North Andover, Massachusetts, United States · On-site
Mid level
Dermatologist – North Andover, MA (Opening 2027) Optima Dermatology is seeking a Board Certified / Board Eligible General Dermatologist to join our new practice in North Andover, MA, opening in 2027. This is an exception…
Skills: General Dermatology, Patient Care, Clinical Excellence, EMR Proficiency
Translational Medicine Lead, Oncology Therapy Area, R&D, Orion Corporation
Boston, Massachusetts, United States · Hybrid
$130k–$300k/yr
Senior
Are you a visionary scientist with a passion for oncology and translational research? Do you thrive at the intersection of discovery and clinical development? We are seeking a strategic and scientifically rigorous Transl…
Skills: Translational Medicine Strategy, Biomarker Development, Oncology Drug Development, Companion Diagnostics, Matrix Leadership
Company Description Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bi…
Skills: Biostatistics, Oncology Clinical Trials, People Management, Clinical Development Strategy, Regulatory Guidelines
The role of QSP Modeling Lead will be responsible for generating and implementing mechanistic pharmacology models to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding…
Skills: QSP Modeling, Model-Informed Drug Development, Python, R, MATLAB
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Administrative Support, Literature Reviews, Data Management, IRB Compliance, REDCap
Associate Director, Analytical Development – Small Molecule
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company
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$180k–$195k/yr
Full-time
postgraduate degree
401(k) Plan, Medical Insurance, Dental Insurance, Vision Insurance, Life Insurance, Paid Time Off
Posted 26d ago
~40 hrs/week
Responsibilities
Oversee small molecule analytical activities and manage external CDMOs to ensure timely delivery of data. Lead method development, validation, and stability studies while contributing to regulatory filings such as INDs and NDAs.
Requirements
Requires a PhD in Chemistry or Pharmaceutical Sciences (or MS with extensive experience) and over 10 years of biotech/pharmaceutical industry experience. Must possess deep technical knowledge of analytical assays, cGMP, and ICH stability guidelines.
Full job description
Description of Role
Centessa continues to expand its CMC group and currently seeks anAssociate Director of Analytical R&D within the CMCgroup. The successful candidate will have hands-on experience leading the execution of small molecule analytical activities across early to late-stage development. This position will oversee work with various vendors and oversee analytical functions across programs. Comprehensive working knowledge of cGMP and regulatory guidance as they relate to development, testing, characterization, and shelf-life management of biologics is paramount. This position will be accountable for design, execution, and reporting of analytical data at external CDMOs to meet company deliverables and timelines. Travel to vendors both domestically and internationally will be required.
Key Responsibilities
Support analytical development activities related to method development and qualification/validation, product characterization, and comparability assessment for multiple programs
Work in a team environment to manage drug substance and drug product analytical development activities primarily at third-party vendors including analytical method implementation, qualification/validation, and transfer for drug substance and drug product projects
Review method validation protocols, reports, and transfer activities
Review test data for release, stability, and characterization plans for projects
Save and store documentation, generate stability result tables, file stability data and results data
Monitor stability due dates and coordinate data transfer from vendors
Review analytical documents including but not limited to protocols, reports, and procedures
Act as the CMC team analytical representative member in cross functional developmental teams
Contribute to CMC analytical aspects of regulatory filings; review and assemble information for analytical sections in regulatory submission documents (e.g. IND, IMPD, NDA, etc)
Coordinate and execute domestic and international shipments
Serve as a technical expert and aid in analytical investigations and troubleshooting
Assist with batch record review and deviation investigations
Qualifications
PhD in Chemistry, Pharmaceutical Sciences, or a related discipline or MS with extensive relevant biotech/pharmaceutical industry experience
10+ years of experience in biotech/pharmaceutical industry in small molecules, working in early to late-development (pre-clinical to phase 3)
Strong analytical planning and resource management skills in a dynamic environment located across multiple geographies
In depth knowledge of assay and related substances development, forced degradation, HPLC/UPLC, GC, KF, XRPD, residual solvents, elemental impurities, microbial testing, dissolution, compendial methods.
Hands-on experience in carrying out stability studies for drug substance and drug product in development and/or QC settings
Experience managing DS/DP stability, and knowledge of ICH stability guidelines
Knowledge of compendial (USP, EP, etc) requirements and standards
Detailed knowledge and understanding of current Good Manufacturing Practices (cGMP) related to the QC laboratory and ability to identify/remediate gaps in processes or systems
Strong organizational skills and attention to detail
Good interpersonal and communication skills to collaborate effectively with internal and external business partners
Requires a good understanding of managing groups, CMOs, CDMOs and other vendors
Work Location
The Associate Director, Analytical Development role is based in the US, with occasional travel.
Compensation
The annual base salary range for this position is $170,000.00 to $195,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge.
In addition to base pay, this role is eligible for a discretionary annual bonus. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.
POSITION: Full-Time, Exempt
EEOC Statement: Centessa Pharmaceuticals, a wholly owned subdisary of Eli Lilly and Company believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.
Related keywords
Small MoleculeAnalytical R&DCMCcGMPCDMOMethod ValidationStability StudiesHPLCUPLCGCXRPDICH GuidelinesUSPEPINDIMPD
Frequently asked questions
How much do Science & Research jobs in Massachusetts pay?
Based on 4280 listings with disclosed salaries, most science & research jobs in Massachusetts pay between $90k–$237k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in Massachusetts right now?
There are currently 6,981 open science & research positions in Massachusetts listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Massachusetts?
Companies currently hiring include Mass General Brigham, Harvard Division of Medical Sciences, Takeda, Sanofi, Thermo Fisher Scientific, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Massachusetts?
Yes — 2166 of the 6981 open science & research positions offer remote or hybrid work (476 remote, 1690 hybrid).
How do I apply for Science & Research jobs in Massachusetts?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
