Nottingham, England, United Kingdom · On-site
About Sygnature Discovery At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ s…
Skills: Chromatography, Preparative HPLC, LCMS, Purification, Data Analysis
Nottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · Hybrid
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CCH GroupNottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
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CCH GroupNottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
Quotient Sciences: Molecule to Cure. Fast. Quotient Sciences is a leading drug development and manufacturing accelerator, helping biotech and pharma companies bring new medicines to patients faster. With over 35 years of…
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Nottingham, England, United Kingdom · Hybrid
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Nottingham, England, United Kingdom · Hybrid
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Nottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
Join the UK’s number one fitness brand and favourite gym as a Personal Trainer/ Fitness Coach Keep 100% of your PT earnings, your first month is rent free. Why be a self-employed Personal Trainer at PureGym? you wi…
Skills: Personal Training, Fitness Coaching, Class Instruction, Member Experience, Gym Floor Maintenance
Nottingham, England, United Kingdom · On-site
Join the UK’s number one fitness brand and favourite gym as a Personal Trainer/ Fitness Coach Keep 100% of your PT earnings, your first month is rent free. Why be a self-employed Personal Trainer at PureGym? you wi…
Skills: Personal Training, Fitness Coaching, Class Instruction, Member Experience, Gym Maintenance
Nottingham, England, United Kingdom · On-site
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Burton upon Trent, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · On-site
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Nottingham, England, United Kingdom · Hybrid
📍 Job Title: Area Manager – The Hearing Care Partnership (THCP) 📌 Region: East Midlands & Anglia 🕘 Location: Field Based + Remote/Home Based 📣 Reporting To: Chris Powell, Head of Operations Be at the Heart of Transfo…
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Develop new chromatographic methods and perform purification of small molecules using preparative HPLC and LCMS. Maintain and troubleshoot analytical instrumentation while improving workflow efficiency for medicinal chemistry projects.
Requires a BSc or MSc in Chemistry or a related subject with core experience in drug discovery and purification. Candidates must be proficient in developing preparative chromatography methods and interpreting chromatographic data.
At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible.
We’re 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment.
Over the past 20 years, we’ve earned a track record of real impact: 60+ advanced candidates, 250 patents filed, 200+ active projects. Over 90% of our customers choose to stay with us – from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges.
If you are interested in accelerating your career in chromatography and working with state-of-the-art technology and instrumentation, then a role in Separation Science is for you.
Separation Scientists at Sygnature Discovery play an essential role in supporting integrated client projects as well as delivering specialist services. The growing team is looking for talented scientists to push our capabilities even further.
Your main role as a Separation Scientist will be to develop new chromatographic methods and to undertake purification by preparative HPLC alongside maintenance of both analytical and preparative instrumentation.
To solve chromatographic problems on a wide and diverse chemical space using state-of-the-art instrumentation
To carry out semi-automated purification process on milligram to gram scale as well as developing bespoke analytical and preparative methods
To undertake preparative and analytical HPLC and LCMS on a daily basis and to troubleshoot instrument problems
To provide achiral purification support to medicinal chemistry project teams and comply with departmental KPIs
To develop high-throughput purification workflows
To propose and implement new initiatives to improve workflow efficiency and enhance chromatographic capabilities
You will have a BSc/MSc in Chemistry (or related subject) with core drug discovery and purification experience
Experienced in chromatographic data analysis and interpretation
Hands on experience of developing preparative chromatography methods using a range of techniques
Hands on experience in applying these methods to the isolation and purification of small molecules over a range of scales
Knowledge and experience of state-of-the-art preparative and analytical instrumentation with the ability to identify and troubleshoot equipment issues
Understand the influence of structural characteristics / chemistry of compounds on chromatographic behaviour
Ability to multitask across different workflows and efficiently prioritise key tasks and requests
Self-motivated and capable of working independently, with a flexible approach and excellent problem-solving skills
Possesses a collaborative mindset and the ability to communicate in a scientific manner with attention to detail
🌴 25 days annual leave (plus bank holidays)
🏥 Private Medical Insurance
🛡️ Life Insurance
🎯 Employee Assistance Programme
⚖️ Enhanced Family Friendly Policies
💰 Sygnature Group Pension Scheme
💚 1 paid volunteer day per year
Please note: This advert may close early if we receive a high volume of applications. We encourage you to submit your application as soon as possible to avoid missing out on this opportunity.
#BeyondBoundaries
At Sygnature Discovery, a global drug discovery CRO, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment. Over the past 20 years, we’ve earned a track record of real impact: 60+ advanced candidates, 200+ patents filed, 200+ active projects. Over 90% of our customers choose to stay with us – from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges. We go Beyond Boundaries to deliver speed without compromising on quality. Founded in 2004, we have delivered over 40 pre-clinical compounds, 21 clinical compounds, and our scientists are named on over 170 patent applications. We partner with global pharma, biotech, and NFP organizations, providing integrated drug discovery services from target identification through to candidate nomination. Our co-located teams are experts in protein science, chemistry, computational chemistry, in vitro biology, pharmacology, DMPK, form and formulation services, and project management, with a core therapeutic focus on oncology, inflammation and immunology, as well as neuroscience, metabolic diseases, respiratory, infectious diseases and fibrotic diseases.
Offices: BioCity, Pennyfoot Street, Nottingham, NG1 1GR, GB · 245 First Street, Cambridge, Massachusetts 02142, US · 611 Gateway Blvd, Suite 120, South San Francisco, California 94080, US · Alderley Park, Alderley Edge, England SK10 4TG, GB
There are currently 101 open healthcare positions in Nottingham, United Kingdom listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Mercy Medical Center, Baltimore, MD, CCH Group, Quotient Sciences, Ramsay Health Care UK, Sygnature Discovery, among others. Browse the listings above to see every active employer.
Yes — 19 of the 101 open healthcare positions offer remote or hybrid work (2 remote, 17 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
